Gallic acid (hydrate)_HEC-1-A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FTL ferritin, light polypeptide 0.0824886
RPL23 ribosomal protein L23 0.0797516
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0782733
TPT1 tumor protein, translationally-controlled 1 0.0605448
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0531924
RPL12 ribosomal protein L12 0.0530157
RPS19 ribosomal protein S19 0.0524096
RPS8 ribosomal protein S8 0.0482113
RPS12 ribosomal protein S12 0.0434701
RPL31 ribosomal protein L31 0.0431183
RPL35A ribosomal protein L35a 0.0429583
B2M beta-2-microglobulin 0.0392367
RPL19 ribosomal protein L19 0.0348371
RPLP1 ribosomal protein, large, P1 0.0338519
RPL26 ribosomal protein L26 0.0332213
RPL34 ribosomal protein L34 0.0315114
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0313586
RPLP2 ribosomal protein, large, P2 0.0310356
RPS14 ribosomal protein S14 0.0307582
RPL35 ribosomal protein L35 0.0295564
RPS6 ribosomal protein S6 0.0289124
RPS3 ribosomal protein S3 0.0286742
NAP1L1 nucleosome assembly protein 1-like 1 0.0275167
RPL36 ribosomal protein L36 0.0272641
ZNF292 zinc finger protein 292 0.0260984
EIF1 eukaryotic translation initiation factor 1 0.0260319
RPL18 ribosomal protein L18 0.0258325
RPL11 ribosomal protein L11 0.0257021
GOLGA4 golgin A4 0.0254411
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0253967
RACK1 receptor for activated C kinase 1 0.0253564
MT2A metallothionein 2A 0.0245762
RPS4X ribosomal protein S4, X-linked 0.0245204
TRA2A transformer 2 alpha homolog (Drosophila) 0.024437
RPS27A ribosomal protein S27a 0.0242144
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0239699
BHLHE40 basic helix-loop-helix family, member e40 0.0234812
RPS27 ribosomal protein S27 0.0227997
RPS17 ribosomal protein S17 0.022427
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0222564
KDM3A lysine (K)-specific demethylase 3A 0.0222077
RPL28 ribosomal protein L28 0.0218418
RPS2 ribosomal protein S2 0.0217586
APP amyloid beta (A4) precursor protein 0.0216896
RPL37A ribosomal protein L37a 0.0213788
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0211103
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0207724
RPL32 ribosomal protein L32 0.0205883
MATR3 matrin 3 0.0205417
RLF rearranged L-myc fusion 0.0196292
RPLP0 ribosomal protein, large, P0 0.0195399
SQSTM1 sequestosome 1 0.019411
RPL9 ribosomal protein L9 0.01931
HELZ helicase with zinc finger 0.0191346
RPS5 ribosomal protein S5 0.0189449
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0188209
RPS16 ribosomal protein S16 0.0185586
RPS20 ribosomal protein S20 0.0182371
OGA O-GlcNAcase 0.0180434
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0176665
RPS29 ribosomal protein S29 0.0175538
RPL13A ribosomal protein L13a 0.0172346
SKP1 S-phase kinase-associated protein 1 0.0172076
DDIT4 DNA-damage-inducible transcript 4 0.0171755
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0169769
RPL7 ribosomal protein L7 0.0166372
S100A9 S100 calcium binding protein A9 0.0166188
SPAG9 sperm associated antigen 9 0.0164648
HMGB2 high mobility group box 2 0.0159161
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0153176
NAMPT nicotinamide phosphoribosyltransferase 0.0152722
RPS24 ribosomal protein S24 0.0147092
FXR1 fragile X mental retardation, autosomal homolog 1 0.0146131
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 0.0145826
RPL27 ribosomal protein L27 0.0144722
RPS25 ribosomal protein S25 0.0144244
KIF5B kinesin family member 5B 0.0142129
NRIP1 nuclear receptor interacting protein 1 0.0139024
TMSB10 thymosin beta 10 0.0138744
RYBP RING1 and YY1 binding protein 0.013859
SERINC1 serine incorporator 1 0.0138556
CANX calnexin 0.0136834
RPL14 ribosomal protein L14 0.0135996
RPL38 ribosomal protein L38 0.0135018
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.0134735
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0134648
RPL21 ribosomal protein L21 0.0133905
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0133397
UQCRB ubiquinol-cytochrome c reductase binding protein 0.0133084
LCORL ligand dependent nuclear receptor corepressor-like 0.0132987
SMAD3 SMAD family member 3 0.0132114
CALR calreticulin 0.0131275
PUM1 pumilio RNA-binding family member 1 0.0129829
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0129756
ANKRD33B ankyrin repeat domain 33B 0.0127297
SET SET nuclear proto-oncogene 0.012704
GPX4 glutathione peroxidase 4 0.0126609
RYK receptor-like tyrosine kinase 0.0124996
UGCG UDP-glucose ceramide glucosyltransferase 0.0124855
TOP2B topoisomerase (DNA) II beta 180kDa 0.0124734

decreased expression

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 -0.076745
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0733312
ASPH aspartate beta-hydroxylase -0.0599651
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0558965
PSD3 pleckstrin and Sec7 domain containing 3 -0.0518675
TPM4 tropomyosin 4 -0.0467417
NDRG1 N-myc downstream regulated 1 -0.0444859
DLC1 DLC1 Rho GTPase activating protein -0.0443028
EGFR epidermal growth factor receptor -0.0439315
LIMCH1 LIM and calponin homology domains 1 -0.0436949
CD44 CD44 molecule (Indian blood group) -0.0435223
BICD1 bicaudal D homolog 1 (Drosophila) -0.0427796
ZBTB20 zinc finger and BTB domain containing 20 -0.0416993
HMGA1 high mobility group AT-hook 1 -0.0401445
CCND1 cyclin D1 -0.0401021
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0388076
POTEF POTE ankyrin domain family, member F -0.0384033
SVIL supervillin -0.0367887
HMGA2 high mobility group AT-hook 2 -0.0356095
VCL vinculin -0.035607
ALCAM activated leukocyte cell adhesion molecule -0.0328766
LPP LIM domain containing preferred translocation partner in lipoma -0.0328408
DSCAML1 Down syndrome cell adhesion molecule like 1 -0.0312118
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0302449
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0298978
RHEX regulator of hemoglobinization and erythroid cell expansion -0.0294593
VCAN versican -0.0294017
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.029245
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0291169
ACTG1 actin gamma 1 -0.0288397
BPTF bromodomain PHD finger transcription factor -0.0287263
FLNB filamin B, beta -0.0285864
EGR1 early growth response 1 -0.0285621
DIAPH3 diaphanous-related formin 3 -0.0281135
TBC1D5 TBC1 domain family, member 5 -0.027807
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0273518
ITGA6 integrin, alpha 6 -0.0271025
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0270253
SEPTIN9 septin 9 -0.0268198
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0267087
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0264145
PAX8 paired box 8 -0.0258905
RAD51B RAD51 paralog B -0.025567
LAMA4 laminin, alpha 4 -0.0251614
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0243969
CAPN2 calpain 2, (m/II) large subunit -0.0241817
MKI67 marker of proliferation Ki-67 -0.0235225
ITGB8 integrin, beta 8 -0.0231266
KRT7 keratin 7, type II -0.0230781
NF1 neurofibromin 1 -0.0228489
PKM pyruvate kinase, muscle -0.0226906
MAML2 mastermind-like 2 (Drosophila) -0.0225333
PCED1B PC-esterase domain containing 1B -0.022481
ATG7 autophagy related 7 -0.0220224
LDHA lactate dehydrogenase A -0.0218083
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0217472
LAMC2 laminin, gamma 2 -0.0216973
PATJ PATJ crumbs cell polarity complex component -0.0216725
PTPRK protein tyrosine phosphatase, receptor type, K -0.0213553
SMYD3 SET and MYND domain containing 3 -0.0212309
SH3KBP1 SH3-domain kinase binding protein 1 -0.0210318
CDCP1 CUB domain containing protein 1 -0.0206859
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.0205097
FHIT fragile histidine triad -0.0202138
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.019997
FLNA filamin A, alpha -0.019547
DOCK4 dedicator of cytokinesis 4 -0.0193048
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0191336
EHBP1 EH domain binding protein 1 -0.0189777
GPR39 G protein-coupled receptor 39 -0.0187012
ZMYND8 zinc finger, MYND-type containing 8 -0.0186755
WASF2 WAS protein family, member 2 -0.0186743
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0185915
F3 coagulation factor III (thromboplastin, tissue factor) -0.0185124
PTK2 protein tyrosine kinase 2 -0.0183814
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -0.0183147
ACTN4 actinin, alpha 4 -0.0182388
CREB5 cAMP responsive element binding protein 5 -0.0182247
OSBPL10 oxysterol binding protein-like 10 -0.0180828
ZFHX3 zinc finger homeobox 3 -0.0177624
N4BP2L2 NEDD4 binding protein 2-like 2 -0.017703
GLIS3 GLIS family zinc finger 3 -0.0174926
ANXA3 annexin A3 -0.0171628
FNDC3B fibronectin type III domain containing 3B -0.0171239
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats -0.0169372
FNIP1 folliculin interacting protein 1 -0.0169079
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -0.0168067
MAP4 microtubule-associated protein 4 -0.0165767
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -0.0164317
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0162825
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.016029
TNIK TRAF2 and NCK interacting kinase -0.0159689
AXL AXL receptor tyrosine kinase -0.0155982
ZNF609 zinc finger protein 609 -0.0155933
AHNAK AHNAK nucleoprotein -0.0155177
PDGFC platelet derived growth factor C -0.0153872
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0152982
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0151479
THSD4 thrombospondin, type I, domain containing 4 -0.0150486
TCF12 transcription factor 12 -0.014608