Gallic acid (hydrate)_HOP62 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in HOP62 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0652324
TRIO trio Rho guanine nucleotide exchange factor 0.0551694
NAV1 neuron navigator 1 0.046754
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0463093
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0420856
RPS6 ribosomal protein S6 0.0400838
MYO10 myosin X 0.0381913
HMGA2 high mobility group AT-hook 2 0.0355447
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0345883
AKAP12 A kinase (PRKA) anchor protein 12 0.0327906
RFX8 RFX family member 8, lacking RFX DNA binding domain 0.031555
TPT1 tumor protein, translationally-controlled 1 0.0309508
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0304873
NALF1 NALCN channel auxiliary factor 1 0.0281179
RPL35A ribosomal protein L35a 0.02762
WWOX WW domain containing oxidoreductase 0.0271047
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0239051
DTNA dystrobrevin, alpha 0.0226669
AFF3 AF4/FMR2 family, member 3 0.0212284
RPLP1 ribosomal protein, large, P1 0.0212071
RPL23 ribosomal protein L23 0.0207795
DIAPH2 diaphanous-related formin 2 0.0205268
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0200103
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0195798
RPS8 ribosomal protein S8 0.0187734
ARHGAP22 Rho GTPase activating protein 22 0.0186488
ZSWIM6 zinc finger, SWIM-type containing 6 0.0177666
EFNA5 ephrin-A5 0.0175674
EXT1 exostosin glycosyltransferase 1 0.0175096
MPRIP myosin phosphatase Rho interacting protein 0.0174883
PTPRM protein tyrosine phosphatase, receptor type, M 0.017427
KIAA1549L KIAA1549-like 0.0164972
RAD51B RAD51 paralog B 0.0152143
INTS6 integrator complex subunit 6 0.0150674
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0148685
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0146621
COL6A3 collagen, type VI, alpha 3 0.0143771
FRMD4A FERM domain containing 4A 0.0142802
EGFR epidermal growth factor receptor 0.0142799
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0141051
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0140029
MTSS1 metastasis suppressor 1 0.013594
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.013521
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0134964
MAML3 mastermind-like 3 (Drosophila) 0.0134437
LRMDA leucine rich melanocyte differentiation associated 0.0134081
RRM2 ribonucleotide reductase M2 0.0132462
PRSS23 protease, serine, 23 0.0132018
RPS19 ribosomal protein S19 0.0131666
PTK2 protein tyrosine kinase 2 0.012835
RPL12 ribosomal protein L12 0.0127645
ATXN1 ataxin 1 0.0126687
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0122311
ZBTB38 zinc finger and BTB domain containing 38 0.0121681
VEGFA vascular endothelial growth factor A 0.0119217
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0118879
PPARD peroxisome proliferator-activated receptor delta 0.0117644
ANKRD11 ankyrin repeat domain 11 0.0115739
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.0115115
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 0.0114303
MT1E metallothionein 1E 0.0112276
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.011118
PRKCA protein kinase C, alpha 0.0110842
RPL37A ribosomal protein L37a 0.0110478
CLMP CXADR-like membrane protein 0.011012
MAP1B microtubule-associated protein 1B 0.0109672
DIAPH3 diaphanous-related formin 3 0.0109609
RPL37 ribosomal protein L37 0.0109077
FBXL7 F-box and leucine-rich repeat protein 7 0.0107793
PODXL podocalyxin-like 0.0107037
LHFPL2 lipoma HMGIC fusion partner-like 2 0.0107026
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0105759
GPC5 glypican 5 0.0104914
RPS20 ribosomal protein S20 0.0103531
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0103469
ABTB3 ankyrin repeat and BTB domain containing 3 0.0102726
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0102704
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 0.0100147
BICD1 bicaudal D homolog 1 (Drosophila) 0.00981863
RPS2 ribosomal protein S2 0.00977549
MSN moesin 0.0096052
RPL11 ribosomal protein L11 0.00958328
SH3RF3 SH3 domain containing ring finger 3 0.00949042
RPL9 ribosomal protein L9 0.00945497
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.00938959
SQSTM1 sequestosome 1 0.00926399
RPL34 ribosomal protein L34 0.00921221
RPL26 ribosomal protein L26 0.0091208
AHRR aryl-hydrocarbon receptor repressor 0.00899675
CEP112 centrosomal protein 112kDa 0.00891043
RPLP0 ribosomal protein, large, P0 0.00884555
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.00873655
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.00861633
PRH1 proline-rich protein HaeIII subfamily 1 0.00855598
RPL31 ribosomal protein L31 0.00854089
ANTXR1 anthrax toxin receptor 1 0.00847014
CFAP20DC CFAP20 domain containing 0.00834308
CEP128 centrosomal protein 128kDa 0.00831238
RPS27 ribosomal protein S27 0.00826421
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.00825484

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.322514
FN1 fibronectin 1 -0.240916
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.166282
VIM vimentin -0.134005
UBC ubiquitin C -0.0661401
ENO1 enolase 1, (alpha) -0.0586955
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0558701
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0550881
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0546427
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0520146
PTMA prothymosin, alpha -0.0509165
IGF2 insulin-like growth factor 2 -0.0502401
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0488529
CANX calnexin -0.0473421
LOX lysyl oxidase -0.0470807
CALU calumenin -0.0441099
AHNAK AHNAK nucleoprotein -0.040877
P4HB prolyl 4-hydroxylase, beta polypeptide -0.040673
NGLY1 N-glycanase 1 -0.0373292
TENM2 teneurin transmembrane protein 2 -0.0362143
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0357293
PKM pyruvate kinase, muscle -0.0333088
HDLBP high density lipoprotein binding protein -0.0321846
ANKRD28 ankyrin repeat domain 28 -0.0316186
CD44 CD44 molecule (Indian blood group) -0.0311542
TMSB10 thymosin beta 10 -0.0307904
RPS27A ribosomal protein S27a -0.0303743
PGK1 phosphoglycerate kinase 1 -0.0297131
NDRG1 N-myc downstream regulated 1 -0.0295406
ELL2 elongation factor, RNA polymerase II, 2 -0.0290014
LDHA lactate dehydrogenase A -0.0287627
CCND1 cyclin D1 -0.0280223
CD109 CD109 molecule -0.0280058
PDIA4 protein disulfide isomerase family A, member 4 -0.0270248
GOLGA4 golgin A4 -0.0257204
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0255294
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0254883
GLG1 golgi glycoprotein 1 -0.0254846
PDIA6 protein disulfide isomerase family A, member 6 -0.0254119
CDCP1 CUB domain containing protein 1 -0.0251867
SPAG9 sperm associated antigen 9 -0.0247302
RTN4 reticulon 4 -0.0244904
COL1A1 collagen, type I, alpha 1 -0.0242678
ZMYND8 zinc finger, MYND-type containing 8 -0.0237333
LOC112694756 uncharaterized LOC112694756 -0.0234764
PDE10A phosphodiesterase 10A -0.0233544
FLNB filamin B, beta -0.0233488
SETD5 SET domain containing 5 -0.0229838
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0229191
NAMPT nicotinamide phosphoribosyltransferase -0.0222743
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0222593
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0220607
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.022007
TXNIP thioredoxin interacting protein -0.021954
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0218031
OGA O-GlcNAcase -0.0215009
JUN jun proto-oncogene -0.0213922
NF1 neurofibromin 1 -0.0208766
EGR1 early growth response 1 -0.0204295
THBS1 thrombospondin 1 -0.0202893
PCBP2 poly(rC) binding protein 2 -0.0199888
RNMT RNA (guanine-7-) methyltransferase -0.0197449
TGFBI transforming growth factor, beta-induced, 68kDa -0.0196428
IL1B interleukin 1, beta -0.0195639
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0192571
FNDC3B fibronectin type III domain containing 3B -0.0192423
ASPH aspartate beta-hydroxylase -0.0192338
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.019072
WDR45B WD repeat domain 45B -0.0189551
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.0187683
TNNC1 troponin C type 1 (slow) -0.018735
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0185375
PDIA3 protein disulfide isomerase family A, member 3 -0.0181002
TM4SF1 transmembrane 4 L six family member 1 -0.0180693
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0179988
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0177886
WASF2 WAS protein family, member 2 -0.0176533
LCORL ligand dependent nuclear receptor corepressor-like -0.0176497
INHBA inhibin, beta A -0.0175694
NECTIN2 nectin cell adhesion molecule 2 -0.0175524
NIPBL Nipped-B homolog (Drosophila) -0.0174118
KDM3A lysine (K)-specific demethylase 3A -0.0170611
CXCL8 chemokine (C-X-C motif) ligand 8 -0.017002
SBF2 SET binding factor 2 -0.0168521
BIRC6 baculoviral IAP repeat containing 6 -0.0167987
USP34 ubiquitin specific peptidase 34 -0.0166657
TUBB6 tubulin, beta 6 class V -0.0163038
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0161916
CALR calreticulin -0.0160546
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.0158206
EIF1 eukaryotic translation initiation factor 1 -0.0157505
RB1CC1 RB1-inducible coiled-coil 1 -0.0156912
FLNA filamin A, alpha -0.0156624
ANTXR2 anthrax toxin receptor 2 -0.0155782
AFF4 AF4/FMR2 family, member 4 -0.0155758
PCBP3 poly(rC) binding protein 3 -0.0152034
RRBP1 ribosome binding protein 1 -0.0150458
IGFBP4 insulin-like growth factor binding protein 4 -0.0149476
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0148099
ZFAND3 zinc finger, AN1-type domain 3 -0.014771