Gallic acid (hydrate)_HS-578T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in HS-578T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.140116
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.127426
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0859152
ENO1 enolase 1, (alpha) 0.0751364
ERRFI1 ERBB receptor feedback inhibitor 1 0.0602653
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0596608
CAVIN1 caveolae associated protein 1 0.0523113
CXCL8 chemokine (C-X-C motif) ligand 8 0.044584
ASPH aspartate beta-hydroxylase 0.0393249
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0385914
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0385602
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0370919
LDHA lactate dehydrogenase A 0.0369705
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0358912
CANX calnexin 0.0356229
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0305732
DST dystonin 0.0305169
ALCAM activated leukocyte cell adhesion molecule 0.0294864
BZW1 basic leucine zipper and W2 domains 1 0.0285505
MYH9 myosin, heavy chain 9, non-muscle 0.0278366
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0275888
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.026535
VCAN versican 0.0264166
AKAP12 A kinase (PRKA) anchor protein 12 0.0243642
IGFBP7 insulin-like growth factor binding protein 7 0.0225056
ECE1 endothelin converting enzyme 1 0.0223582
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0222283
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0219788
DSPP dentin sialophosphoprotein 0.0207482
ANXA2 annexin A2 0.0205151
RAD21 RAD21 homolog (S. pombe) 0.0196651
LARS1 leucyl-tRNA synthetase 1 0.0193025
IER3 immediate early response 3 0.0192239
NFE2L1 nuclear factor, erythroid 2-like 1 0.0192059
HSPA8 heat shock 70kDa protein 8 0.0185727
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0184561
NAP1L1 nucleosome assembly protein 1-like 1 0.0182753
FAM107B family with sequence similarity 107, member B 0.0180713
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0177992
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0174976
ARHGAP29 Rho GTPase activating protein 29 0.0174407
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0173903
KTN1 kinectin 1 (kinesin receptor) 0.0172063
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0171796
PDIA3 protein disulfide isomerase family A, member 3 0.0170477
HILPDA hypoxia inducible lipid droplet-associated 0.0165895
TMSB4X thymosin beta 4, X-linked 0.0158665
SQSTM1 sequestosome 1 0.0158622
PGK1 phosphoglycerate kinase 1 0.0156475
CCDC47 coiled-coil domain containing 47 0.0155776
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.0155717
RPS2 ribosomal protein S2 0.0154064
BIRC3 baculoviral IAP repeat containing 3 0.0151511
BHLHE40 basic helix-loop-helix family, member e40 0.0151341
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0151238
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0150665
MYO10 myosin X 0.0148678
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0146086
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0144359
RSL1D1 ribosomal L1 domain containing 1 0.013995
TMED2 transmembrane emp24 domain trafficking protein 2 0.0139789
CAPN2 calpain 2, (m/II) large subunit 0.0136776
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.013585
CENPF centromere protein F, 350/400kDa 0.0135835
TPR translocated promoter region, nuclear basket protein 0.0135758
TMF1 TATA element modulatory factor 1 0.0132102
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0131746
MXI1 MAX interactor 1, dimerization protein 0.0130783
TPM3 tropomyosin 3 0.0130683
MCFD2 multiple coagulation factor deficiency 2 0.0130516
PHF3 PHD finger protein 3 0.0129758
ADD3 adducin 3 (gamma) 0.0129669
CCPG1 cell cycle progression 1 0.012899
SERINC1 serine incorporator 1 0.0127538
RBBP7 retinoblastoma binding protein 7 0.0127468
PEAK1 pseudopodium-enriched atypical kinase 1 0.0125618
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0124918
AKAP9 A kinase (PRKA) anchor protein 9 0.0124465
AHCYL1 adenosylhomocysteinase-like 1 0.0124157
COPB1 coatomer protein complex, subunit beta 1 0.0123261
MACF1 microtubule-actin crosslinking factor 1 0.0122993
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0122627
SET SET nuclear proto-oncogene 0.0122566
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0122043
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0121875
SLK STE20-like kinase 0.0120658
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0120477
KDM3A lysine (K)-specific demethylase 3A 0.0120306
TBX3 T-box 3 0.0120022
BTG1 B-cell translocation gene 1, anti-proliferative 0.0119545
LAMC2 laminin, gamma 2 0.0118719
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0118271
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0118226
RSRC2 arginine/serine-rich coiled-coil 2 0.0118053
MYOF myoferlin 0.0117989
SDF4 stromal cell derived factor 4 0.0116858
MKI67 marker of proliferation Ki-67 0.0115902
NIPBL Nipped-B homolog (Drosophila) 0.0115684
FN1 fibronectin 1 0.0114415
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0114331

decreased expression

Symbol Name Standardized Value
COL1A1 collagen, type I, alpha 1 -0.310817
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.228686
TMSB10 thymosin beta 10 -0.189091
NDRG1 N-myc downstream regulated 1 -0.172955
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.168589
COL6A3 collagen, type VI, alpha 3 -0.135637
NKAIN3 Na+/K+ transporting ATPase interacting 3 -0.0977561
PSD3 pleckstrin and Sec7 domain containing 3 -0.0964983
MT2A metallothionein 2A -0.0873371
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0863729
DPYD dihydropyrimidine dehydrogenase -0.0828656
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0813216
EXT1 exostosin glycosyltransferase 1 -0.0724923
FTL ferritin, light polypeptide -0.0681867
ZBTB20 zinc finger and BTB domain containing 20 -0.0660516
COL1A2 collagen, type I, alpha 2 -0.0612455
FNDC3B fibronectin type III domain containing 3B -0.0599784
S100A9 S100 calcium binding protein A9 -0.0536928
CD44 CD44 molecule (Indian blood group) -0.0532768
FTH1 ferritin, heavy polypeptide 1 -0.0532626
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0484052
COL5A1 collagen, type V, alpha 1 -0.0480365
COL7A1 collagen, type VII, alpha 1 -0.0474538
MT1X metallothionein 1X -0.0470933
TGFBI transforming growth factor, beta-induced, 68kDa -0.0463201
FBN1 fibrillin 1 -0.0455922
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0450198
CDH13 cadherin 13 -0.0442187
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0441845
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0439259
VEGFA vascular endothelial growth factor A -0.043772
RPS19 ribosomal protein S19 -0.0435521
RPS6 ribosomal protein S6 -0.0433876
GRB10 growth factor receptor-bound protein 10 -0.0425348
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0421179
RPL28 ribosomal protein L28 -0.0417992
RPL8 ribosomal protein L8 -0.0407941
TRPS1 trichorhinophalangeal syndrome I -0.0387336
CYB5R3 cytochrome b5 reductase 3 -0.0386938
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0386667
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.0383538
TMEM165 transmembrane protein 165 -0.0369222
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.035956
SMYD3 SET and MYND domain containing 3 -0.035817
LY6E lymphocyte antigen 6 complex, locus E -0.0357572
COL6A2 collagen, type VI, alpha 2 -0.035292
CADM1 cell adhesion molecule 1 -0.0350964
JARID2 jumonji, AT rich interactive domain 2 -0.0344128
HLA-A major histocompatibility complex, class I, A -0.0328546
PFN1 profilin 1 -0.0328421
F3 coagulation factor III (thromboplastin, tissue factor) -0.0320107
PDE4D phosphodiesterase 4D, cAMP-specific -0.031525
RICTOR RPTOR independent companion of MTOR, complex 2 -0.031498
RPS11 ribosomal protein S11 -0.0313576
NALF1 NALCN channel auxiliary factor 1 -0.0311741
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0303651
RPL36 ribosomal protein L36 -0.0302924
WASF2 WAS protein family, member 2 -0.0301692
DPYSL3 dihydropyrimidinase-like 3 -0.0297653
PTK2 protein tyrosine kinase 2 -0.0296915
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0296557
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0295512
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0290728
SRPK2 SRSF protein kinase 2 -0.0286953
ANKRD11 ankyrin repeat domain 11 -0.0285205
TRAM1 translocation associated membrane protein 1 -0.0282127
ACTG1 actin gamma 1 -0.0281026
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0280833
TAPBP TAP binding protein (tapasin) -0.0274888
TPM1 tropomyosin 1 (alpha) -0.0271825
MAP4 microtubule-associated protein 4 -0.0270977
VIM vimentin -0.0269367
BSG basigin (Ok blood group) -0.0259482
CD99 CD99 molecule -0.0259174
PDE10A phosphodiesterase 10A -0.0259129
CLIC4 chloride intracellular channel 4 -0.0259114
RRBP1 ribosome binding protein 1 -0.0258703
LOC112694756 uncharaterized LOC112694756 -0.0257889
RPS8 ribosomal protein S8 -0.0256834
HLA-B major histocompatibility complex, class I, B -0.0254661
TPM2 tropomyosin 2 (beta) -0.0254031
ZFAND3 zinc finger, AN1-type domain 3 -0.0249636
CAMTA1 calmodulin binding transcription activator 1 -0.0247524
AHNAK AHNAK nucleoprotein -0.0245726
RPS21 ribosomal protein S21 -0.0245301
GSK3B glycogen synthase kinase 3 beta -0.0243143
OSMR oncostatin M receptor -0.0242948
UQCRB ubiquinol-cytochrome c reductase binding protein -0.024284
RPLP1 ribosomal protein, large, P1 -0.0240848
SBF2 SET binding factor 2 -0.0239084
TUBB tubulin, beta class I -0.023895
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -0.0238917
RPL35A ribosomal protein L35a -0.0238391
RAB6A RAB6A, member RAS oncogene family -0.023605
RAB7A RAB7A, member RAS oncogene family -0.0235019
VCL vinculin -0.0232798
SMIM44 small integral membrane protein 44 -0.0232653
TENM3 teneurin transmembrane protein 3 -0.0231451
MAML2 mastermind-like 2 (Drosophila) -0.0229876
RPL32 ribosomal protein L32 -0.0227892