Gallic acid (hydrate)_HT-29 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in HT-29 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
INTS6 integrator complex subunit 6 0.0416314
ERRFI1 ERBB receptor feedback inhibitor 1 0.0279586
ZSWIM6 zinc finger, SWIM-type containing 6 0.0177814
RPL35A ribosomal protein L35a 0.0166599
NCEH1 neutral cholesterol ester hydrolase 1 0.0165746
VEGFA vascular endothelial growth factor A 0.0158815
NTN4 netrin 4 0.0155019
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0139952
NUCB2 nucleobindin 2 0.013994
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.013676
FTH1 ferritin, heavy polypeptide 1 0.0133356
CCNYL1 cyclin Y-like 1 0.0132965
VIM vimentin 0.0121482
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.0114225
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0113032
IGFBP3 insulin-like growth factor binding protein 3 0.0111824
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0110269
MARCHF3 membrane associated ring-CH-type finger 3 0.0110233
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.010799
EGR1 early growth response 1 0.0104806
MT2A metallothionein 2A 0.0101114
GLCCI1 glucocorticoid induced 1 0.00990949
HOMER1 homer scaffolding protein 1 0.00978924
AGR2 anterior gradient 2 0.00974027
AREG amphiregulin 0.00957221
FAM13A family with sequence similarity 13, member A 0.00945222
FN1 fibronectin 1 0.00922561
LRRC23 leucine rich repeat containing 23 0.00917071
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 0.0089651
TLE4 transducin-like enhancer of split 4 0.00893906
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00861408
SERTAD2 SERTA domain containing 2 0.00855746
AKAP12 A kinase (PRKA) anchor protein 12 0.008475
HILPDA hypoxia inducible lipid droplet-associated 0.00838276
LURAP1L leucine rich adaptor protein 1-like 0.00837656
LARP1B La ribonucleoprotein domain family, member 1B 0.00822384
WLS wntless Wnt ligand secretion mediator 0.00789796
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.00782439
HLA-B major histocompatibility complex, class I, B 0.00778577
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00777636
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.00772764
NALF1 NALCN channel auxiliary factor 1 0.00772183
EGFR epidermal growth factor receptor 0.00760106
NABP1 nucleic acid binding protein 1 0.00753705
SPIRE1 spire-type actin nucleation factor 1 0.0074969
AHRR aryl-hydrocarbon receptor repressor 0.00729093
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.00702297
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.00699798
UBAP2 ubiquitin associated protein 2 0.00699473
PRR5L proline rich 5 like 0.00681353
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00680829
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.00677914
C19ORF38 chromosome 19 open reading frame 38 0.00674374
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 0.00662924
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00662073
ENO2 enolase 2 (gamma, neuronal) 0.00656369
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.00641084
ISG15 ISG15 ubiquitin-like modifier 0.00635102
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00634366
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 0.00634267
STC1 stanniocalcin 1 0.00623376
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.00623039
NMUR2 neuromedin U receptor 2 0.006226
CDH13 cadherin 13 0.00613595
ERN1 endoplasmic reticulum to nucleus signaling 1 0.00610239
LOXL2 lysyl oxidase-like 2 0.00601503
C5AR1 complement component 5a receptor 1 0.00598705
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00597211
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00594872
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00594186
CYB5R3 cytochrome b5 reductase 3 0.00590901
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.00587346
HAP1 huntingtin-associated protein 1 0.00580413
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00578904
RBMS3 RNA binding motif, single stranded interacting protein 3 0.00578386
RIGI RNA sensor RIG-I 0.00575334
FLACC1 flagellum associated containing coiled-coil domains 1 0.00572169
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00565065
RPS26 ribosomal protein S26 0.00561517
HDAC9 histone deacetylase 9 0.00558289
ERO1B endoplasmic reticulum oxidoreductase 1 beta 0.00557956
CSTB cystatin B (stefin B) 0.00555492
TNS1 tensin 1 0.00550085
OSMR oncostatin M receptor 0.00548762
NAV2 neuron navigator 2 0.00546645
COL5A2 collagen, type V, alpha 2 0.00539982
ADM adrenomedullin 0.00538512
SHISA5 shisa family member 5 0.00532033
AUTS2 autism susceptibility candidate 2 0.00528135
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.00527775
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.00523622
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.00516592
GPC6 glypican 6 0.00516348
AVIL advillin 0.00514651
DNHD1 dynein heavy chain domain 1 0.00511758
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.00508884
HKDC1 hexokinase domain containing 1 0.00507124
INPP1 inositol polyphosphate-1-phosphatase 0.00504416
PLSCR2 phospholipid scramblase 2 0.00502245
HBEGF heparin-binding EGF-like growth factor 0.00498319

decreased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein -0.14898
ACTN4 actinin, alpha 4 -0.110133
TXNRD1 thioredoxin reductase 1 -0.0994145
RAD21 RAD21 homolog (S. pombe) -0.090655
PTMA prothymosin, alpha -0.0895208
UBC ubiquitin C -0.085175
EZR ezrin -0.0764417
PTK2 protein tyrosine kinase 2 -0.076344
KRT8 keratin 8, type II -0.0754657
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0729148
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0682667
NECTIN2 nectin cell adhesion molecule 2 -0.0640619
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0639387
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0603482
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0594865
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.058141
RPS27A ribosomal protein S27a -0.0545546
PDIA4 protein disulfide isomerase family A, member 4 -0.054415
LYZ lysozyme -0.054359
ANXA2 annexin A2 -0.0541852
NF1 neurofibromin 1 -0.0536731
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0534553
ITPKC inositol-trisphosphate 3-kinase C -0.0520141
TMSB10 thymosin beta 10 -0.051619
SLC45A4 solute carrier family 45, member 4 -0.0508686
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0498359
SAMD12 sterile alpha motif domain containing 12 -0.0497832
JUN jun proto-oncogene -0.048489
STK24 serine/threonine kinase 24 -0.0474252
GARS1 glycyl-tRNA synthetase 1 -0.0473053
KRT18 keratin 18, type I -0.0469899
EEF2 eukaryotic translation elongation factor 2 -0.0460949
NAMPT nicotinamide phosphoribosyltransferase -0.0455956
PLAUR plasminogen activator, urokinase receptor -0.0454152
PARP4 poly (ADP-ribose) polymerase family, member 4 -0.0453236
OGA O-GlcNAcase -0.0444874
CANX calnexin -0.0444723
HDLBP high density lipoprotein binding protein -0.0442299
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0438805
RPL23 ribosomal protein L23 -0.0438721
RBM39 RNA binding motif protein 39 -0.0429256
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0427804
KMT2C lysine (K)-specific methyltransferase 2C -0.0424287
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.041925
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0417779
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0406264
ACTG1 actin gamma 1 -0.040297
FAT1 FAT atypical cadherin 1 -0.040033
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0384002
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -0.0381872
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0381676
CD2AP CD2-associated protein -0.0381354
PGK1 phosphoglycerate kinase 1 -0.0379659
ZMYM2 zinc finger, MYM-type 2 -0.0378901
RPS3 ribosomal protein S3 -0.0376977
ANKRD12 ankyrin repeat domain 12 -0.0374544
PRRC2C proline-rich coiled-coil 2C -0.0354009
TPT1 tumor protein, translationally-controlled 1 -0.0352775
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.034856
MKI67 marker of proliferation Ki-67 -0.0343658
ANKRD11 ankyrin repeat domain 11 -0.0342663
PCBP2 poly(rC) binding protein 2 -0.0339786
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0339679
SBF2 SET binding factor 2 -0.0338726
ETV6 ets variant 6 -0.0338182
LOC112694756 uncharaterized LOC112694756 -0.0338153
ENO1 enolase 1, (alpha) -0.0337645
PDZD8 PDZ domain containing 8 -0.0337208
MBNL1 muscleblind-like splicing regulator 1 -0.0335677
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0335552
WWC1 WW and C2 domain containing 1 -0.0335375
TM9SF3 transmembrane 9 superfamily member 3 -0.0334919
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0331668
MYH9 myosin, heavy chain 9, non-muscle -0.033148
SQSTM1 sequestosome 1 -0.0329847
PATJ PATJ crumbs cell polarity complex component -0.032581
RPLP1 ribosomal protein, large, P1 -0.0325142
PTPRF protein tyrosine phosphatase, receptor type, F -0.0323247
EPCAM epithelial cell adhesion molecule -0.0320174
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.031838
KDM3A lysine (K)-specific demethylase 3A -0.0315788
WASF2 WAS protein family, member 2 -0.0314964
DSCAM Down syndrome cell adhesion molecule -0.0314205
ATAD2 ATPase family, AAA domain containing 2 -0.031298
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.0311031
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -0.0310906
TRAPPC9 trafficking protein particle complex 9 -0.0310462
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0310427
RRBP1 ribosome binding protein 1 -0.0309137
RPL4 ribosomal protein L4 -0.0306265
RHEB Ras homolog enriched in brain -0.0304527
GMDS GDP-mannose 4,6-dehydratase -0.0304232
JMJD1C jumonji domain containing 1C -0.0303669
GSK3B glycogen synthase kinase 3 beta -0.0300065
MARCHF6 membrane associated ring-CH-type finger 6 -0.0298987
CYRIB CYFIP related Rac1 interactor B -0.0297998
S100A6 S100 calcium binding protein A6 -0.029786
TOP1 topoisomerase (DNA) I -0.0297515
COG5 component of oligomeric golgi complex 5 -0.0297498
AKAP13 A kinase (PRKA) anchor protein 13 -0.0294931