Gallic acid (hydrate)_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LAMC2 laminin, gamma 2 0.0766068
TPT1 tumor protein, translationally-controlled 1 0.0654006
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0578888
AHNAK AHNAK nucleoprotein 0.0576638
CAVIN1 caveolae associated protein 1 0.0537039
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0526318
ANXA2 annexin A2 0.0502028
RAI14 retinoic acid induced 14 0.0491025
MACF1 microtubule-actin crosslinking factor 1 0.0481582
BZW1 basic leucine zipper and W2 domains 1 0.0468592
PGK1 phosphoglycerate kinase 1 0.0454418
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0452978
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0442853
RIGI RNA sensor RIG-I 0.043476
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0414557
TMSB4X thymosin beta 4, X-linked 0.0414324
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0410161
ENO1 enolase 1, (alpha) 0.0404661
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0401908
EMP1 epithelial membrane protein 1 0.0396397
HLA-E major histocompatibility complex, class I, E 0.0392896
MEF2A myocyte enhancer factor 2A 0.0345132
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0337455
TIMP3 TIMP metallopeptidase inhibitor 3 0.0336608
ASPH aspartate beta-hydroxylase 0.0320533
SAMD9 sterile alpha motif domain containing 9 0.0305855
DUSP6 dual specificity phosphatase 6 0.0303841
KDM3A lysine (K)-specific demethylase 3A 0.0302
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0284691
BHLHE40 basic helix-loop-helix family, member e40 0.0273564
CANX calnexin 0.0272931
AHNAK2 AHNAK nucleoprotein 2 0.0265598
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0265445
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.0258706
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0256221
OGA O-GlcNAcase 0.0249374
ARHGAP5 Rho GTPase activating protein 5 0.0245345
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.024416
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0237058
IFI16 interferon, gamma-inducible protein 16 0.0230361
STK4 serine/threonine kinase 4 0.0226621
RSL1D1 ribosomal L1 domain containing 1 0.0219629
TPM3 tropomyosin 3 0.0219049
IFIH1 interferon induced with helicase C domain 1 0.0212383
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0209283
CALU calumenin 0.0209182
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0207801
EZR ezrin 0.0207305
CD9 CD9 molecule 0.0205647
CAPN2 calpain 2, (m/II) large subunit 0.0203482
TPR translocated promoter region, nuclear basket protein 0.0200976
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0200735
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0200714
RIOK3 RIO kinase 3 0.0200186
SLK STE20-like kinase 0.0198588
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.0198303
CSTB cystatin B (stefin B) 0.0198066
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.0197574
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0197563
CEP170 centrosomal protein 170kDa 0.0194645
CALB1 calbindin 1, 28kDa 0.0191763
MTSS1 metastasis suppressor 1 0.0189485
ANXA1 annexin A1 0.018721
HSPA8 heat shock 70kDa protein 8 0.0186932
RRBP1 ribosome binding protein 1 0.0183846
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.01833
ZFC3H1 zinc finger, C3H1-type containing 0.0180742
SDCBP syndecan binding protein (syntenin) 0.0179672
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0178968
PAIP2 poly(A) binding protein interacting protein 2 0.0178789
IER3 immediate early response 3 0.0178597
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0176286
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.0175443
SDCCAG8 serologically defined colon cancer antigen 8 0.0174678
SULF1 sulfatase 1 0.0172693
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0172568
RASA3 RAS p21 protein activator 3 0.0170011
ZNFX1 zinc finger, NFX1-type containing 1 0.0169906
FAM114A1 family with sequence similarity 114, member A1 0.0169784
SQSTM1 sequestosome 1 0.0169311
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0167168
EHF ets homologous factor 0.0167134
CEP350 centrosomal protein 350kDa 0.0166097
WARS1 tryptophanyl-tRNA synthetase 1 0.0166
SEPTIN10 septin 10 0.0165228
MYH9 myosin, heavy chain 9, non-muscle 0.0165049
DSCAM Down syndrome cell adhesion molecule 0.0162978
ENOSF1 enolase superfamily member 1 0.0162908
EIF5B eukaryotic translation initiation factor 5B 0.0160843
CCDC47 coiled-coil domain containing 47 0.0160794
SET SET nuclear proto-oncogene 0.0159673
DSPP dentin sialophosphoprotein 0.015776
CEP250 centrosomal protein 250kDa 0.0157619
GOLGB1 golgin B1 0.0154356
IQGAP1 IQ motif containing GTPase activating protein 1 0.0153203
STAT1 signal transducer and activator of transcription 1, 91kDa 0.015316
SPAG9 sperm associated antigen 9 0.015286
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0151825
AKAP12 A kinase (PRKA) anchor protein 12 0.0148063
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0146942

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.121127
FLNB filamin B, beta -0.0968433
POTEF POTE ankyrin domain family, member F -0.0947399
RPS21 ribosomal protein S21 -0.093359
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0872999
ALCAM activated leukocyte cell adhesion molecule -0.0837437
TMSB10 thymosin beta 10 -0.0806692
B2M beta-2-microglobulin -0.0691284
HSPG2 heparan sulfate proteoglycan 2 -0.0688334
PALLD palladin, cytoskeletal associated protein -0.0600272
DOCK5 dedicator of cytokinesis 5 -0.0591471
FNDC3B fibronectin type III domain containing 3B -0.057457
DPYD dihydropyrimidine dehydrogenase -0.0573955
NDRG1 N-myc downstream regulated 1 -0.0570349
CYB5R3 cytochrome b5 reductase 3 -0.0556004
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0551264
CD44 CD44 molecule (Indian blood group) -0.054621
RPS6 ribosomal protein S6 -0.0539231
TGM2 transglutaminase 2 -0.0532097
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0503052
RPLP2 ribosomal protein, large, P2 -0.0499988
LAMA5 laminin, alpha 5 -0.0498315
TRIO trio Rho guanine nucleotide exchange factor -0.0487011
FOXO1 forkhead box O1 -0.0483371
IFI27 interferon, alpha-inducible protein 27 -0.0478271
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0475651
CLU clusterin -0.0475433
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0470374
CEMIP cell migration inducing protein, hyaluronan binding -0.0466127
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0454657
PDLIM5 PDZ and LIM domain 5 -0.0439843
RPS8 ribosomal protein S8 -0.0427976
SLC38A2 solute carrier family 38, member 2 -0.0411444
RPS19 ribosomal protein S19 -0.0405586
RPS13 ribosomal protein S13 -0.0400095
PCDH1 protocadherin 1 -0.0398719
PTK2 protein tyrosine kinase 2 -0.0398302
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.038279
IGF2 insulin-like growth factor 2 -0.0378757
TINAGL1 tubulointerstitial nephritis antigen-like 1 -0.0377548
LY6E lymphocyte antigen 6 complex, locus E -0.0374845
S100A9 S100 calcium binding protein A9 -0.0374092
EFHD2 EF-hand domain family, member D2 -0.0368784
AOPEP aminopeptidase O (putative) -0.0364684
ANKRD33B ankyrin repeat domain 33B -0.0362465
TSC22D1 TSC22 domain family, member 1 -0.0357244
PDE4D phosphodiesterase 4D, cAMP-specific -0.035705
ITCH itchy E3 ubiquitin protein ligase -0.0350254
MDK midkine (neurite growth-promoting factor 2) -0.0346926
RPS23 ribosomal protein S23 -0.0345395
FOXP1 forkhead box P1 -0.0345204
MYO10 myosin X -0.0337464
MBNL1 muscleblind-like splicing regulator 1 -0.0337316
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0333643
RPS14 ribosomal protein S14 -0.0332119
HDAC9 histone deacetylase 9 -0.0323176
NCOR2 nuclear receptor corepressor 2 -0.0322329
BCL2L1 BCL2-like 1 -0.032113
PTMA prothymosin, alpha -0.0321064
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0309966
RPL11 ribosomal protein L11 -0.0308317
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0308236
IFITM3 interferon induced transmembrane protein 3 -0.0305441
TAPBP TAP binding protein (tapasin) -0.0304829
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0304207
DYNLRB1 dynein, light chain, roadblock-type 1 -0.0304099
MRPS6 mitochondrial ribosomal protein S6 -0.029784
FTL ferritin, light polypeptide -0.0293718
FTH1 ferritin, heavy polypeptide 1 -0.0292855
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0292852
HMGA1 high mobility group AT-hook 1 -0.0292798
CDKN2A cyclin-dependent kinase inhibitor 2A -0.0291553
HMGA2 high mobility group AT-hook 2 -0.0291297
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0290346
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0286753
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0281477
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0280197
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0279245
BSG basigin (Ok blood group) -0.0276714
TAGLN2 transgelin 2 -0.0276376
CMIP c-Maf inducing protein -0.0275287
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0273057
ASTN2 astrotactin 2 -0.0272621
PKM pyruvate kinase, muscle -0.027126
RASAL2 RAS protein activator like 2 -0.0270202
RBM39 RNA binding motif protein 39 -0.0268063
SERTAD2 SERTA domain containing 2 -0.0265442
MBNL2 muscleblind-like splicing regulator 2 -0.0264686
NECTIN1 nectin cell adhesion molecule 1 -0.0264577
IFI6 interferon, alpha-inducible protein 6 -0.0260535
RPL28 ribosomal protein L28 -0.0258962
RPS25 ribosomal protein S25 -0.0256756
RAB6A RAB6A, member RAS oncogene family -0.0256388
CNRIP1 cannabinoid receptor interacting protein 1 -0.0256196
RPL21 ribosomal protein L21 -0.0254491
PFN1 profilin 1 -0.0254106
WASF2 WAS protein family, member 2 -0.0252931
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0252299
TNS4 tensin 4 -0.0251604
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0250339