Gallic acid (hydrate)_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in J82 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0776686
UGCG UDP-glucose ceramide glucosyltransferase 0.0566135
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0536027
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.049685
FTL ferritin, light polypeptide 0.0453639
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0451394
MT2A metallothionein 2A 0.0307228
PDIA3 protein disulfide isomerase family A, member 3 0.0301849
SET SET nuclear proto-oncogene 0.028212
UBA6 ubiquitin-like modifier activating enzyme 6 0.0281049
KTN1 kinectin 1 (kinesin receptor) 0.0277215
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0251177
ZNF841 zinc finger protein 841 0.0227272
KMT2E lysine (K)-specific methyltransferase 2E 0.0209479
TPM3 tropomyosin 3 0.0191567
TSC22D2 TSC22 domain family, member 2 0.0187437
ANXA1 annexin A1 0.0183919
NUP58 nucleoporin 58 0.0180178
ZNF292 zinc finger protein 292 0.0179875
ENO1 enolase 1, (alpha) 0.0179303
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0175752
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0175376
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.017343
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0167148
JUN jun proto-oncogene 0.0166982
AKAP12 A kinase (PRKA) anchor protein 12 0.0162853
CCNL1 cyclin L1 0.0161955
HILPDA hypoxia inducible lipid droplet-associated 0.0159718
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0158331
ADM adrenomedullin 0.0156044
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0152771
ADAM9 ADAM metallopeptidase domain 9 0.015252
BHLHE40 basic helix-loop-helix family, member e40 0.0148536
FXR1 fragile X mental retardation, autosomal homolog 1 0.0144615
SPAG9 sperm associated antigen 9 0.0144512
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0144399
APLP2 amyloid beta (A4) precursor-like protein 2 0.0141333
MSN moesin 0.0140647
RPL23 ribosomal protein L23 0.0138336
MYH9 myosin, heavy chain 9, non-muscle 0.0136492
ATP13A3 ATPase type 13A3 0.0133274
NAP1L1 nucleosome assembly protein 1-like 1 0.0132616
RIOK3 RIO kinase 3 0.0131688
BRD2 bromodomain containing 2 0.0130379
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0130294
B2M beta-2-microglobulin 0.0127525
DTNA dystrobrevin, alpha 0.0127451
CENPF centromere protein F, 350/400kDa 0.0124859
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0124528
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0124519
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0123588
USP3 ubiquitin specific peptidase 3 0.0123486
ZFP36L1 ZFP36 ring finger protein-like 1 0.0122778
PLIN2 perilipin 2 0.0121629
QKI QKI, KH domain containing, RNA binding 0.0121486
RYBP RING1 and YY1 binding protein 0.0120286
FTH1 ferritin, heavy polypeptide 1 0.0119955
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0118549
PDS5B PDS5 cohesin associated factor B 0.0118414
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0118267
WSB1 WD repeat and SOCS box containing 1 0.0117719
TPD52 tumor protein D52 0.0116989
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0116788
KIF5B kinesin family member 5B 0.0116161
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0115489
RND3 Rho family GTPase 3 0.0115292
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0114725
RPS6 ribosomal protein S6 0.0111848
MATR3 matrin 3 0.0111523
PLK2 polo-like kinase 2 0.0110099
DENND4C DENN/MADD domain containing 4C 0.0108791
EZR ezrin 0.0108634
CANX calnexin 0.0108321
YBX1 Y box binding protein 1 0.0108319
GOLGA4 golgin A4 0.0107969
TPR translocated promoter region, nuclear basket protein 0.0107336
PCBP2 poly(rC) binding protein 2 0.0105352
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.0105128
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0105027
RNF145 ring finger protein 145 0.0104691
LIMA1 LIM domain and actin binding 1 0.010445
ELL2 elongation factor, RNA polymerase II, 2 0.0101542
RSRC2 arginine/serine-rich coiled-coil 2 0.0101027
KIF13A kinesin family member 13A 0.00989913
ARRDC3 arrestin domain containing 3 0.00987949
WAC WW domain containing adaptor with coiled-coil 0.00974819
RLF rearranged L-myc fusion 0.0096919
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00965288
HMGB2 high mobility group box 2 0.00959255
FOSL1 FOS-like antigen 1 0.00955139
DSTN destrin (actin depolymerizing factor) 0.00951467
PTPRJ protein tyrosine phosphatase, receptor type, J 0.00926739
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00925985
RPS12 ribosomal protein S12 0.00922358
ESYT2 extended synaptotagmin-like protein 2 0.00911964
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.00911167
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.00905238
EGLN1 egl-9 family hypoxia-inducible factor 1 0.00904372
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.00903121
USP12 ubiquitin specific peptidase 12 0.00900601

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.117813
NALF1 NALCN channel auxiliary factor 1 -0.0802856
HLA-B major histocompatibility complex, class I, B -0.0640234
EXT1 exostosin glycosyltransferase 1 -0.0611223
ABI3BP ABI family, member 3 (NESH) binding protein -0.0494208
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0451188
CD44 CD44 molecule (Indian blood group) -0.0413223
GLIS3 GLIS family zinc finger 3 -0.0363182
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0362434
AHNAK AHNAK nucleoprotein -0.0326089
PHACTR1 phosphatase and actin regulator 1 -0.0324259
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0314537
OSMR oncostatin M receptor -0.0296045
ACTG1 actin gamma 1 -0.0259267
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0243113
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0232777
F3 coagulation factor III (thromboplastin, tissue factor) -0.0231197
COL5A1 collagen, type V, alpha 1 -0.0220325
ZBTB20 zinc finger and BTB domain containing 20 -0.0204657
HLA-C major histocompatibility complex, class I, C -0.0195101
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0192715
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.0188192
TUBB tubulin, beta class I -0.0184319
POSTN periostin, osteoblast specific factor -0.0182747
TMSB10 thymosin beta 10 -0.0179289
NAMPT nicotinamide phosphoribosyltransferase -0.0178119
FLNB filamin B, beta -0.0178091
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0177649
STARD13 StAR-related lipid transfer (START) domain containing 13 -0.0168
FSTL1 follistatin-like 1 -0.0163835
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0163787
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0158181
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.015505
SLC12A8 solute carrier family 12, member 8 -0.0154485
FLNA filamin A, alpha -0.015417
RAB7A RAB7A, member RAS oncogene family -0.015224
ZNF804A zinc finger protein 804A -0.0150764
PRRC2B proline-rich coiled-coil 2B -0.0149506
SLIT2 slit homolog 2 (Drosophila) -0.0147921
PLCB4 phospholipase C, beta 4 -0.0146769
PODXL podocalyxin-like -0.0146039
PTPRF protein tyrosine phosphatase, receptor type, F -0.014342
IARS1 isoleucyl-tRNA synthetase 1 -0.0142651
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0140183
ZXDC ZXD family zinc finger C -0.0137526
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.0137174
SAMD12 sterile alpha motif domain containing 12 -0.0135674
FOXP1 forkhead box P1 -0.0132627
SENP5 SUMO1/sentrin specific peptidase 5 -0.013202
GOLGA3 golgin A3 -0.0130549
CLTC clathrin, heavy chain (Hc) -0.0130151
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0122384
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0122213
SCFD2 sec1 family domain containing 2 -0.0121477
SBF2 SET binding factor 2 -0.01177
CCND1 cyclin D1 -0.0117456
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0117401
STAU1 staufen double-stranded RNA binding protein 1 -0.0117171
VCL vinculin -0.0115278
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0114714
ZMYND8 zinc finger, MYND-type containing 8 -0.0113725
DPYD dihydropyrimidine dehydrogenase -0.0113225
SLC38A2 solute carrier family 38, member 2 -0.0112941
CTSD cathepsin D -0.0111048
SDK1 sidekick cell adhesion molecule 1 -0.0110367
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) -0.0108937
DLG1 discs, large homolog 1 (Drosophila) -0.0107696
LARP4B La ribonucleoprotein domain family, member 4B -0.0107523
MON2 MON2 homolog (S. cerevisiae) -0.0106257
LOC112694756 uncharaterized LOC112694756 -0.0106019
HM13 histocompatibility (minor) 13 -0.0105785
MAP4 microtubule-associated protein 4 -0.0105267
ZNFX1 zinc finger, NFX1-type containing 1 -0.0104721
TMEM263 transmembrane protein 263 -0.0103759
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0103012
CCBE1 collagen and calcium binding EGF domains 1 -0.0102936
CDK13 cyclin-dependent kinase 13 -0.0102419
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0101605
TENM3 teneurin transmembrane protein 3 -0.0101523
ATG7 autophagy related 7 -0.00997536
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.00992922
FUS FUS RNA binding protein -0.00985378
FNIP1 folliculin interacting protein 1 -0.0098012
TLN1 talin 1 -0.00978074
LOXL2 lysyl oxidase-like 2 -0.00977143
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.00972749
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -0.00972184
TPM1 tropomyosin 1 (alpha) -0.00967003
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.00964327
NUP214 nucleoporin 214kDa -0.00949033
DIAPH3 diaphanous-related formin 3 -0.00947165
PARD3B par-3 family cell polarity regulator beta -0.00945058
CALU calumenin -0.00936687
HEG1 heart development protein with EGF-like domains 1 -0.0092633
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00918605
TAS2R14 taste receptor, type 2, member 14 -0.00914255
BLZF1 basic leucine zipper nuclear factor 1 -0.00914131
ZNF432 zinc finger protein 432 -0.00912171
MAML2 mastermind-like 2 (Drosophila) -0.00907404
PTPRG protein tyrosine phosphatase, receptor type, G -0.00898759