Gallic acid (hydrate)_LOX-IMVI Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0223926
FTL ferritin, light polypeptide 0.0210164
MT2A metallothionein 2A 0.0180372
RPL21 ribosomal protein L21 0.0166025
RPL23 ribosomal protein L23 0.0162176
MT1X metallothionein 1X 0.0141187
HAS2 hyaluronan synthase 2 0.0137423
KLF6 Kruppel-like factor 6 0.0131919
YBX3 Y box binding protein 3 0.0127525
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0124426
CENPF centromere protein F, 350/400kDa 0.0119607
RPL18 ribosomal protein L18 0.0115528
PLK2 polo-like kinase 2 0.011236
PFN1 profilin 1 0.0106418
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0104819
MYL12B myosin, light chain 12B, regulatory 0.0100046
ARRDC3 arrestin domain containing 3 0.00965328
CAV1 caveolin 1, caveolae protein, 22kDa 0.00959731
MT1E metallothionein 1E 0.00923725
MAP1B microtubule-associated protein 1B 0.00922325
TPI1 triosephosphate isomerase 1 0.00909068
CCNL1 cyclin L1 0.0089618
CSDE1 cold shock domain containing E1, RNA-binding 0.00890803
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.00879875
ZFP36L1 ZFP36 ring finger protein-like 1 0.00821596
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00791495
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.00763521
ELL2 elongation factor, RNA polymerase II, 2 0.00740578
HILPDA hypoxia inducible lipid droplet-associated 0.00713759
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0070726
TMEM87A transmembrane protein 87A 0.00706942
BSG basigin (Ok blood group) 0.00704492
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00704042
SYAP1 synapse associated protein 1 0.00702506
JUN jun proto-oncogene 0.00701645
SREK1IP1 SREK1-interacting protein 1 0.00653538
CD109 CD109 molecule 0.00652215
TUBB tubulin, beta class I 0.00649331
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00640583
BLZF1 basic leucine zipper nuclear factor 1 0.00621094
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.00617609
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00610778
HMGN5 high mobility group nucleosome binding domain 5 0.00610571
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00601085
KIF2C kinesin family member 2C 0.00595691
NOCT nocturnin 0.00592691
CBX3 chromobox homolog 3 0.00589319
TNNC1 troponin C type 1 (slow) 0.00589257
SUGCT succinyl-CoA:glutarate-CoA transferase 0.00587021
NKD1 naked cuticle homolog 1 (Drosophila) 0.00583549
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 0.0058119
CDK17 cyclin-dependent kinase 17 0.00572322
PLIN2 perilipin 2 0.00564929
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00562973
KIF18A kinesin family member 18A 0.00561927
TAFA2 TAFA chemokine like family member 2 0.00560888
TBK1 TANK-binding kinase 1 0.00556506
SS18 synovial sarcoma translocation, chromosome 18 0.00553147
SGO2 shugoshin 2 0.00552989
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00548688
ATP5F1E ATP synthase F1 subunit epsilon 0.00547071
ARF4 ADP-ribosylation factor 4 0.00544216
DENND1B DENN/MADD domain containing 1B 0.00542214
IFITM3 interferon induced transmembrane protein 3 0.00537376
SMIM44 small integral membrane protein 44 0.00534137
GLIPR1 GLI pathogenesis-related 1 0.00533825
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0052001
PCCA propionyl CoA carboxylase, alpha polypeptide 0.00517743
RARB retinoic acid receptor, beta 0.00515019
RPS4X ribosomal protein S4, X-linked 0.00514194
SPRED2 sprouty-related, EVH1 domain containing 2 0.00513081
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.00508093
TPX2 TPX2, microtubule-associated 0.00505096
NUSAP1 nucleolar and spindle associated protein 1 0.00501671
PMP22 peripheral myelin protein 22 0.00494586
KISS1 KiSS-1 metastasis-suppressor 0.00493843
TET3 tet methylcytosine dioxygenase 3 0.00492614
NRG1 neuregulin 1 0.0049254
SPAG16 sperm associated antigen 16 0.0048884
WEE1 WEE1 G2 checkpoint kinase 0.00486429
AKAP13 A kinase (PRKA) anchor protein 13 0.00480095
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.00478633
TSC22D1 TSC22 domain family, member 1 0.00474613
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00471737
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.00471197
TBC1D23 TBC1 domain family, member 23 0.0046831
ERGIC2 ERGIC and golgi 2 0.00465423
USF2 upstream transcription factor 2, c-fos interacting 0.00464877
CCDC34 coiled-coil domain containing 34 0.00458512
CCNK cyclin K 0.00458298
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.00456555
TXNIP thioredoxin interacting protein 0.00454746
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.00453292
SKAP2 src kinase associated phosphoprotein 2 0.00453095
NME7 NME/NM23 family member 7 0.00452476
CEP290 centrosomal protein 290kDa 0.00449804
OSER1 oxidative stress responsive serine-rich 1 0.00448921
ECT2 epithelial cell transforming 2 0.00447134
BCL2L14 BCL2-like 14 (apoptosis facilitator) 0.00447051
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.00446872

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.20154
DTNA dystrobrevin, alpha -0.136601
AKAP12 A kinase (PRKA) anchor protein 12 -0.116106
VIM vimentin -0.112086
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0917654
EXT1 exostosin glycosyltransferase 1 -0.087176
RPS6 ribosomal protein S6 -0.086333
ACTG1 actin gamma 1 -0.0765318
EFNA5 ephrin-A5 -0.0708463
PRKG1 protein kinase, cGMP-dependent, type I -0.0665567
PTMA prothymosin, alpha -0.0624591
PHACTR1 phosphatase and actin regulator 1 -0.0536986
KIAA1217 KIAA1217 -0.0511658
LSAMP limbic system-associated membrane protein -0.0496098
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0492967
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.04798
PTPRG protein tyrosine phosphatase, receptor type, G -0.0479575
TPT1 tumor protein, translationally-controlled 1 -0.0477891
USP34 ubiquitin specific peptidase 34 -0.0464979
PTK2 protein tyrosine kinase 2 -0.0450812
ASPH aspartate beta-hydroxylase -0.0449198
PKM pyruvate kinase, muscle -0.0437573
RUNX1 runt-related transcription factor 1 -0.0435173
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 -0.0423955
EIF1 eukaryotic translation initiation factor 1 -0.0421397
CDH13 cadherin 13 -0.0404855
RPL38 ribosomal protein L38 -0.0403014
MYO10 myosin X -0.0402924
RPLP1 ribosomal protein, large, P1 -0.0395777
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -0.0391345
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0389154
RPL35A ribosomal protein L35a -0.0384231
SAMD4A sterile alpha motif domain containing 4A -0.0379867
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0379637
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0374654
DSCAM Down syndrome cell adhesion molecule -0.0371573
AHNAK AHNAK nucleoprotein -0.0365817
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0358626
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0358086
RPS23 ribosomal protein S23 -0.0356198
KIAA1549L KIAA1549-like -0.0355079
TPM4 tropomyosin 4 -0.0351129
SAMD3 sterile alpha motif domain containing 3 -0.0346161
RPL37A ribosomal protein L37a -0.0346048
TM4SF1 transmembrane 4 L six family member 1 -0.0343893
RPS2 ribosomal protein S2 -0.0341855
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0339917
MACF1 microtubule-actin crosslinking factor 1 -0.0330696
PGK1 phosphoglycerate kinase 1 -0.0329075
KDM3A lysine (K)-specific demethylase 3A -0.0327146
LIMCH1 LIM and calponin homology domains 1 -0.0323344
ERRFI1 ERBB receptor feedback inhibitor 1 -0.032209
CALD1 caldesmon 1 -0.0318382
RPL31 ribosomal protein L31 -0.0314947
EEF2 eukaryotic translation elongation factor 2 -0.0313646
RPS13 ribosomal protein S13 -0.0312289
RPS29 ribosomal protein S29 -0.0312177
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0310257
APP amyloid beta (A4) precursor protein -0.0310221
RPS20 ribosomal protein S20 -0.0301257
NAV1 neuron navigator 1 -0.029836
RPL11 ribosomal protein L11 -0.0298136
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0297925
RPL8 ribosomal protein L8 -0.0292722
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0291143
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0289889
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0289762
RPL7A ribosomal protein L7a -0.0285829
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0285298
ENKUR enkurin, TRPC channel interacting protein -0.0284838
NALF1 NALCN channel auxiliary factor 1 -0.0284362
RPS10 ribosomal protein S10 -0.0280602
LDHA lactate dehydrogenase A -0.0280205
DST dystonin -0.0278938
HSPA8 heat shock 70kDa protein 8 -0.0278764
PRKCE protein kinase C, epsilon -0.0277738
MYH9 myosin, heavy chain 9, non-muscle -0.0274118
RPL4 ribosomal protein L4 -0.02717
RPL5 ribosomal protein L5 -0.0269546
PICALM phosphatidylinositol binding clathrin assembly protein -0.0268828
KPNB1 karyopherin (importin) beta 1 -0.0268285
RPS27A ribosomal protein S27a -0.0266677
GPC6 glypican 6 -0.0266535
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0264406
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0264376
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0264039
SPAG9 sperm associated antigen 9 -0.0263087
RPL13A ribosomal protein L13a -0.026292
RPS25 ribosomal protein S25 -0.026178
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0261019
CDK6 cyclin-dependent kinase 6 -0.0258648
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0257553
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0255736
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.025511
TLE4 transducin-like enhancer of split 4 -0.0254995
BRD2 bromodomain containing 2 -0.0250238
RPS11 ribosomal protein S11 -0.0249876
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.0249835
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0249362
ANTXR2 anthrax toxin receptor 2 -0.0247244