Gallic acid (hydrate)_LS 180 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in LS 180 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
RPS12 ribosomal protein S12 0.146925
RPS2 ribosomal protein S2 0.126535
RPL26 ribosomal protein L26 0.112654
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0996313
RPS3 ribosomal protein S3 0.0920809
RPS19 ribosomal protein S19 0.0876717
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0846782
RPL23 ribosomal protein L23 0.0775093
RPS8 ribosomal protein S8 0.0754459
RPL37A ribosomal protein L37a 0.0721956
FTL ferritin, light polypeptide 0.0720307
RPL31 ribosomal protein L31 0.0661972
RPS6 ribosomal protein S6 0.0625962
RPL36 ribosomal protein L36 0.0622177
RPL12 ribosomal protein L12 0.0585859
PTMA prothymosin, alpha 0.0584821
B2M beta-2-microglobulin 0.0583772
RPL9 ribosomal protein L9 0.0571942
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0559553
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0540687
RPL7 ribosomal protein L7 0.0537436
RPLP2 ribosomal protein, large, P2 0.0536468
RPL18 ribosomal protein L18 0.05254
RPS27 ribosomal protein S27 0.0505968
DSPP dentin sialophosphoprotein 0.0495176
AREG amphiregulin 0.0492637
RPL21 ribosomal protein L21 0.0491115
RPS17 ribosomal protein S17 0.0481226
RPS27A ribosomal protein S27a 0.0479163
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0457409
RPL19 ribosomal protein L19 0.0454383
UQCRB ubiquinol-cytochrome c reductase binding protein 0.0446174
EREG epiregulin 0.0444724
EIF1 eukaryotic translation initiation factor 1 0.0443643
RPL11 ribosomal protein L11 0.0425935
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0415973
TPT1 tumor protein, translationally-controlled 1 0.0411486
RBM39 RNA binding motif protein 39 0.0386801
PRRC2C proline-rich coiled-coil 2C 0.0385059
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.0381691
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0354757
RPL36A ribosomal protein L36a 0.035098
UBE2B ubiquitin-conjugating enzyme E2B 0.0346823
SET SET nuclear proto-oncogene 0.034635
S100P S100 calcium binding protein P 0.0337121
EZR ezrin 0.033245
ARHGAP5 Rho GTPase activating protein 5 0.0331333
MT2A metallothionein 2A 0.0329464
RPS26 ribosomal protein S26 0.0329076
ZFAND3 zinc finger, AN1-type domain 3 0.0321712
NAP1L1 nucleosome assembly protein 1-like 1 0.0319563
PDZD8 PDZ domain containing 8 0.031043
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0309818
APP amyloid beta (A4) precursor protein 0.0308333
RPS14 ribosomal protein S14 0.0308017
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0307125
CSNK1A1 casein kinase 1, alpha 1 0.0306179
NKD1 naked cuticle homolog 1 (Drosophila) 0.0305006
RPS29 ribosomal protein S29 0.0303221
KTN1 kinectin 1 (kinesin receptor) 0.0302089
CEMIP cell migration inducing protein, hyaluronan binding 0.0300313
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0298599
TXNIP thioredoxin interacting protein 0.0295475
ARL15 ADP-ribosylation factor-like 15 0.0292535
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0286551
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0283808
PUM1 pumilio RNA-binding family member 1 0.027524
SPTBN1 spectrin, beta, non-erythrocytic 1 0.02717
PNISR PNN-interacting serine/arginine-rich protein 0.0271433
ERRFI1 ERBB receptor feedback inhibitor 1 0.0268572
RPS7 ribosomal protein S7 0.0263235
ATF4 activating transcription factor 4 0.0263227
RPL7A ribosomal protein L7a 0.0261523
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.0259395
PDIA4 protein disulfide isomerase family A, member 4 0.0258356
EIF4A2 eukaryotic translation initiation factor 4A2 0.0255824
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0255656
SRRM2 serine/arginine repetitive matrix 2 0.0255242
PNN pinin, desmosome associated protein 0.0253985
NDRG1 N-myc downstream regulated 1 0.0253964
RPS25 ribosomal protein S25 0.0247106
GOLGA4 golgin A4 0.0246537
TOP1 topoisomerase (DNA) I 0.0245836
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0243542
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0243455
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0242059
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0241167
KIF5B kinesin family member 5B 0.0239927
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.0239491
KMT2C lysine (K)-specific methyltransferase 2C 0.0239318
TGFBR3 transforming growth factor, beta receptor III 0.0238289
RPS16 ribosomal protein S16 0.0237267
UBE2H ubiquitin-conjugating enzyme E2H 0.0236442
RPS18 ribosomal protein S18 0.0235489
TMF1 TATA element modulatory factor 1 0.0233829
AFDN afadin, adherens junction formation factor 0.0233405
CHD1 chromodomain helicase DNA binding protein 1 0.0229971
LMO7 LIM domain 7 0.0229844
RPS13 ribosomal protein S13 0.0228247
MUC13 mucin 13, cell surface associated 0.0227879

decreased expression

Symbol Name Standardized Value
NPSR1 neuropeptide S receptor 1 -0.160996
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.152773
MUC6 mucin 6, oligomeric mucus/gel-forming -0.148496
FTH1 ferritin, heavy polypeptide 1 -0.111727
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.104077
ACTG1 actin gamma 1 -0.0897971
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.087427
KRT8 keratin 8, type II -0.0847735
VCL vinculin -0.0755735
ANXA2 annexin A2 -0.0673527
KRT18 keratin 18, type I -0.0638874
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0625951
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0608436
ACTN4 actinin, alpha 4 -0.0528739
NALF1 NALCN channel auxiliary factor 1 -0.0518949
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0487185
S100A6 S100 calcium binding protein A6 -0.0483544
POTEF POTE ankyrin domain family, member F -0.0475245
HMGA1 high mobility group AT-hook 1 -0.0473252
GMDS GDP-mannose 4,6-dehydratase -0.0447217
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0432247
LAMA4 laminin, alpha 4 -0.0417577
CCND1 cyclin D1 -0.0416679
MUC17 mucin 17, cell surface associated -0.0412363
HMGB1 high mobility group box 1 -0.0388123
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0378565
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0366281
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.0355964
TFF1 trefoil factor 1 -0.034774
ANTXR2 anthrax toxin receptor 2 -0.0347248
GPHN gephyrin -0.0338913
DEK DEK proto-oncogene -0.0335933
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0327801
CALB1 calbindin 1, 28kDa -0.0323309
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -0.0320743
SLC35F3 solute carrier family 35, member F3 -0.0318
ITGA6 integrin, alpha 6 -0.0314284
DENND1A DENN/MADD domain containing 1A -0.0310104
GREB1L growth regulation by estrogen in breast cancer-like -0.0288606
LOC112694756 uncharaterized LOC112694756 -0.028234
EGR1 early growth response 1 -0.0281939
PDLIM5 PDZ and LIM domain 5 -0.0277601
MUC2 mucin 2, oligomeric mucus/gel-forming -0.027659
AGR2 anterior gradient 2 -0.0275218
KLK10 kallikrein-related peptidase 10 -0.027216
GRB10 growth factor receptor-bound protein 10 -0.0269866
ESYT2 extended synaptotagmin-like protein 2 -0.0268592
GCC2 GRIP and coiled-coil domain containing 2 -0.0264776
EXT1 exostosin glycosyltransferase 1 -0.025857
KPNB1 karyopherin (importin) beta 1 -0.0255899
TUBA1B tubulin, alpha 1b -0.0255059
KRT19 keratin 19, type I -0.0254887
TUBB tubulin, beta class I -0.02529
S100A10 S100 calcium binding protein A10 -0.0251574
SNX9 sorting nexin 9 -0.0250181
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0248811
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0246823
IER3 immediate early response 3 -0.0245961
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0243396
PERP PERP, TP53 apoptosis effector -0.023697
ITGB4 integrin, beta 4 -0.0231937
ARHGAP6 Rho GTPase activating protein 6 -0.0231535
KDM4C lysine (K)-specific demethylase 4C -0.0228856
FLNB filamin B, beta -0.0228169
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -0.0227845
MAML2 mastermind-like 2 (Drosophila) -0.0224775
TFF3 trefoil factor 3 (intestinal) -0.0222095
PIGR polymeric immunoglobulin receptor -0.0221906
MSI2 musashi RNA-binding protein 2 -0.0221139
TAS2R14 taste receptor, type 2, member 14 -0.0221052
RPL8 ribosomal protein L8 -0.0218055
ATP5F1B ATP synthase F1 subunit beta -0.021767
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0214887
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.0212287
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0212014
RAP1B RAP1B, member of RAS oncogene family -0.0209216
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0207429
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -0.0206098
MYH14 myosin, heavy chain 14, non-muscle -0.0204568
ECT2 epithelial cell transforming 2 -0.0203377
LSAMP limbic system-associated membrane protein -0.0202566
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0198258
NBAS neuroblastoma amplified sequence -0.0197407
FOSL1 FOS-like antigen 1 -0.0197263
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase -0.0196028
ARHGAP32 Rho GTPase activating protein 32 -0.0193599
PTPRB protein tyrosine phosphatase, receptor type, B -0.0193326
ABLIM1 actin binding LIM protein 1 -0.0193161
SH3D19 SH3 domain containing 19 -0.0192988
DLG1 discs, large homolog 1 (Drosophila) -0.0192028
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.019107
SORBS2 sorbin and SH3 domain containing 2 -0.018986
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.018967
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.018874
PTPRR protein tyrosine phosphatase, receptor type, R -0.018836
PALLD palladin, cytoskeletal associated protein -0.0188315
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0186066
ALCAM activated leukocyte cell adhesion molecule -0.0186038
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.0182652
FERMT1 fermitin family member 1 -0.0181785