Gallic acid (hydrate)_NCI-H1573 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.129258
LMO7 LIM domain 7 0.0977048
FAM13A family with sequence similarity 13, member A 0.0775869
SLTM SAFB-like, transcription modulator 0.0606411
TES testin LIM domain protein 0.060485
SPAG9 sperm associated antigen 9 0.0585097
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0574708
MYOF myoferlin 0.0569761
RICTOR RPTOR independent companion of MTOR, complex 2 0.0552148
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0523145
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0515064
TOP1 topoisomerase (DNA) I 0.048884
CAV1 caveolin 1, caveolae protein, 22kDa 0.0468745
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0460575
ANXA1 annexin A1 0.0457151
H1-0 H1.0 linker histone 0.0450938
SCEL sciellin 0.0448735
DSCAM Down syndrome cell adhesion molecule 0.0416528
TMCO3 transmembrane and coiled-coil domains 3 0.0406132
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0394212
MT2A metallothionein 2A 0.0382642
HBP1 HMG-box transcription factor 1 0.037341
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0371381
NSUN6 NOP2/Sun domain family, member 6 0.0370559
BRWD1 bromodomain and WD repeat domain containing 1 0.0360075
HOMER1 homer scaffolding protein 1 0.0349541
MORF4L2 mortality factor 4 like 2 0.0345206
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0343568
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0334911
MT1X metallothionein 1X 0.0328272
OGA O-GlcNAcase 0.0320437
GOLGB1 golgin B1 0.0318479
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0318084
RBM39 RNA binding motif protein 39 0.0316985
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.0316936
CXCL8 chemokine (C-X-C motif) ligand 8 0.0315544
NBEAL1 neurobeachin-like 1 0.0310179
ASPH aspartate beta-hydroxylase 0.0309307
ERRFI1 ERBB receptor feedback inhibitor 1 0.0300447
EMP1 epithelial membrane protein 1 0.0299295
BIRC6 baculoviral IAP repeat containing 6 0.0282298
RAB7A RAB7A, member RAS oncogene family 0.0273504
CSTB cystatin B (stefin B) 0.0268806
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0266268
HDLBP high density lipoprotein binding protein 0.0266058
VMP1 vacuole membrane protein 1 0.0265993
SMYD3 SET and MYND domain containing 3 0.0263468
SEC24A SEC24 family member A 0.0263313
RASAL2 RAS protein activator like 2 0.0263288
PDLIM5 PDZ and LIM domain 5 0.0262754
RNMT RNA (guanine-7-) methyltransferase 0.0260931
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0260037
NDRG1 N-myc downstream regulated 1 0.0255454
MACC1 metastasis associated in colon cancer 1 0.0254304
INTS6 integrator complex subunit 6 0.0249211
SON SON DNA binding protein 0.0246913
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.024655
DSPP dentin sialophosphoprotein 0.0246363
EZR ezrin 0.0245815
TPD52 tumor protein D52 0.0244158
SEPTIN2 septin 2 0.0243533
PAPOLA poly(A) polymerase alpha 0.023949
CD163L1 CD163 molecule-like 1 0.0239356
TMSB10 thymosin beta 10 0.0236767
MXI1 MAX interactor 1, dimerization protein 0.0235979
PUM2 pumilio RNA-binding family member 2 0.0234282
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.0234134
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0231959
HELZ helicase with zinc finger 0.0231892
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 0.0231787
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0231128
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0231058
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0229906
FTL ferritin, light polypeptide 0.0229698
SUCO SUN domain containing ossification factor 0.0228335
RNF145 ring finger protein 145 0.0224583
VEGFC vascular endothelial growth factor C 0.0221106
ANKRD37 ankyrin repeat domain 37 0.0217391
JMJD1C jumonji domain containing 1C 0.0214486
YTHDC1 YTH domain containing 1 0.0213522
ZMYM2 zinc finger, MYM-type 2 0.0213369
ZC3H11A zinc finger CCCH-type containing 11A 0.021231
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0211175
RPS3 ribosomal protein S3 0.0210897
ATF6 activating transcription factor 6 0.0210256
ATOSA atos homolog A 0.0209695
RPLP0 ribosomal protein, large, P0 0.0209693
PIBF1 progesterone immunomodulatory binding factor 1 0.0208742
LIMCH1 LIM and calponin homology domains 1 0.0206654
CANX calnexin 0.0203833
TSC22D2 TSC22 domain family, member 2 0.0203605
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0203582
OFD1 oral-facial-digital syndrome 1 0.0203311
GOLGA4 golgin A4 0.0202852
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0202186
RPS4X ribosomal protein S4, X-linked 0.0200352
KDM2A lysine (K)-specific demethylase 2A 0.0198681
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.0198642
TMF1 TATA element modulatory factor 1 0.0197432
LYST lysosomal trafficking regulator 0.0195568

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.17855
EGFR epidermal growth factor receptor -0.132729
ACTG1 actin gamma 1 -0.0931723
LRP1B low density lipoprotein receptor-related protein 1B -0.0897025
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.0895937
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.0875043
EFNA5 ephrin-A5 -0.0643441
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0629074
HLA-B major histocompatibility complex, class I, B -0.0574464
RNF213 ring finger protein 213 -0.0542965
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0503757
CES1 carboxylesterase 1 -0.0484267
MCL1 myeloid cell leukemia 1 -0.0481766
PTMA prothymosin, alpha -0.0458157
TBC1D22A TBC1 domain family, member 22A -0.0444607
ZMYND8 zinc finger, MYND-type containing 8 -0.0440285
S100A10 S100 calcium binding protein A10 -0.0435267
STC1 stanniocalcin 1 -0.0425085
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0400515
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0399693
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0398494
AREG amphiregulin -0.039165
PKM pyruvate kinase, muscle -0.0380996
IFI6 interferon, alpha-inducible protein 6 -0.0379564
SP100 SP100 nuclear antigen -0.0377733
EGR1 early growth response 1 -0.0370834
IGFBP3 insulin-like growth factor binding protein 3 -0.0365492
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0363727
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0358508
FTH1 ferritin, heavy polypeptide 1 -0.0355189
CDCP1 CUB domain containing protein 1 -0.0351614
TRIM56 tripartite motif containing 56 -0.0350388
RAD51B RAD51 paralog B -0.0346969
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.034317
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 -0.0340006
CST3 cystatin C -0.0338243
NAMPT nicotinamide phosphoribosyltransferase -0.0330907
RIGI RNA sensor RIG-I -0.0316402
LAMA4 laminin, alpha 4 -0.0312563
RPS6 ribosomal protein S6 -0.0310702
SMAD3 SMAD family member 3 -0.0306693
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.030492
AKR1C1 aldo-keto reductase family 1, member C1 -0.0301027
CCND1 cyclin D1 -0.0294094
KIAA1217 KIAA1217 -0.0293625
MYO1D myosin ID -0.0292087
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.0288757
OSMR oncostatin M receptor -0.0288543
TXNRD1 thioredoxin reductase 1 -0.0282124
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0280462
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0280359
TPM4 tropomyosin 4 -0.0273831
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.027285
PMP22 peripheral myelin protein 22 -0.0271919
EPAS1 endothelial PAS domain protein 1 -0.0260239
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -0.0260223
RPS29 ribosomal protein S29 -0.025437
RPL37 ribosomal protein L37 -0.0251429
CTSL cathepsin L -0.0250629
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0249433
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0245763
RPL35A ribosomal protein L35a -0.0241894
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0240708
FUS FUS RNA binding protein -0.0240565
MKI67 marker of proliferation Ki-67 -0.0235899
B2M beta-2-microglobulin -0.0231829
CP ceruloplasmin (ferroxidase) -0.0230701
TAPBP TAP binding protein (tapasin) -0.0228397
SLC38A1 solute carrier family 38, member 1 -0.0228186
KPNB1 karyopherin (importin) beta 1 -0.0226493
IGFBP5 insulin-like growth factor binding protein 5 -0.0224307
ANKRD10 ankyrin repeat domain 10 -0.0221656
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.022119
RPL38 ribosomal protein L38 -0.0218505
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0217133
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0216115
GRAMD1B GRAM domain containing 1B -0.0215217
MX1 MX dynamin-like GTPase 1 -0.0213837
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0213582
CEMIP cell migration inducing protein, hyaluronan binding -0.0212533
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.021162
RTN4 reticulon 4 -0.021079
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.0210485
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0209134
LAMC2 laminin, gamma 2 -0.020732
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0207201
NTSR1 neurotensin receptor 1 (high affinity) -0.0204357
TRAF3 TNF receptor-associated factor 3 -0.0203684
RPS25 ribosomal protein S25 -0.0202243
KRT7 keratin 7, type II -0.0201839
PTPRM protein tyrosine phosphatase, receptor type, M -0.0201004
EBF1 early B-cell factor 1 -0.0200486
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.0199977
RPS23 ribosomal protein S23 -0.019757
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0195183
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0192742
MAGEA4 melanoma antigen family A4 -0.0192093
RAN RAN, member RAS oncogene family -0.0191839
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.0191793
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0191549