Gallic acid (hydrate)_NCI-H1792 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
NAMPT nicotinamide phosphoribosyltransferase 0.0889913
PDE4D phosphodiesterase 4D, cAMP-specific 0.0644947
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0465606
HMGA2 high mobility group AT-hook 2 0.0459418
GRB10 growth factor receptor-bound protein 10 0.0427863
PRELID2 PRELI domain containing 2 0.0418623
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0383061
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0360551
IFI44L interferon-induced protein 44-like 0.0352395
RAD51B RAD51 paralog B 0.0340435
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0334459
EFNA5 ephrin-A5 0.0320648
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0310783
PARD3 par-3 family cell polarity regulator 0.0296262
SIK3 SIK family kinase 3 0.0290334
GPC6 glypican 6 0.02844
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.028128
PSD3 pleckstrin and Sec7 domain containing 3 0.0276382
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.0272079
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0271633
SMAD3 SMAD family member 3 0.0270622
FNDC3B fibronectin type III domain containing 3B 0.0254848
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0249703
HAS2 hyaluronan synthase 2 0.0247672
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0242746
EXOC6B exocyst complex component 6B 0.0242329
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0234981
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0234516
RB1CC1 RB1-inducible coiled-coil 1 0.0233476
RARB retinoic acid receptor, beta 0.0231447
UMAD1 UBAP1-MVB12-associated (UMA) domain containing 1 0.0229535
LRMDA leucine rich melanocyte differentiation associated 0.0229244
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0224264
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.021868
STK38L serine/threonine kinase 38 like 0.0218088
LHFPL2 lipoma HMGIC fusion partner-like 2 0.021718
OSBPL3 oxysterol binding protein-like 3 0.0214515
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0214265
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0212676
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0211701
ARHGAP5 Rho GTPase activating protein 5 0.0208575
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0208294
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0207991
ELL2 elongation factor, RNA polymerase II, 2 0.0201929
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0201363
PARP8 poly (ADP-ribose) polymerase family, member 8 0.0198851
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0197878
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.019758
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0195285
ANGPTL4 angiopoietin-like 4 0.019488
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.0194833
MSI2 musashi RNA-binding protein 2 0.0194381
TOP1 topoisomerase (DNA) I 0.0193719
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.0192563
NEK7 NIMA-related kinase 7 0.0183756
ASPH aspartate beta-hydroxylase 0.0183677
CDK6 cyclin-dependent kinase 6 0.018236
PRKCE protein kinase C, epsilon 0.0180179
ZEB1 zinc finger E-box binding homeobox 1 0.0180164
SYT1 synaptotagmin I 0.0175357
MT2A metallothionein 2A 0.0173071
NAP1L1 nucleosome assembly protein 1-like 1 0.0169288
GPAT3 glycerol-3-phosphate acyltransferase 3 0.0168679
FAM13A family with sequence similarity 13, member A 0.0167861
FBXO32 F-box protein 32 0.0165113
FBXL17 F-box and leucine-rich repeat protein 17 0.0162239
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0161853
EREG epiregulin 0.0161414
PDGFC platelet derived growth factor C 0.015811
TXNRD1 thioredoxin reductase 1 0.0156628
MEIS2 Meis homeobox 2 0.0154934
KCTD16 potassium channel tetramerization domain containing 16 0.0154249
APP amyloid beta (A4) precursor protein 0.0154106
TAS2R14 taste receptor, type 2, member 14 0.0153794
ANXA1 annexin A1 0.0153563
BMP2 bone morphogenetic protein 2 0.0153515
JARID2 jumonji, AT rich interactive domain 2 0.0152116
APLP2 amyloid beta (A4) precursor-like protein 2 0.0150393
SS18 synovial sarcoma translocation, chromosome 18 0.0149815
GLS2 glutaminase 2 (liver, mitochondrial) 0.0149371
RUNX1 runt-related transcription factor 1 0.0149036
FAM107B family with sequence similarity 107, member B 0.0147342
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.0147037
SKAP2 src kinase associated phosphoprotein 2 0.0146753
PLSCR1 phospholipid scramblase 1 0.0146414
SPRED2 sprouty-related, EVH1 domain containing 2 0.0145337
AKAP12 A kinase (PRKA) anchor protein 12 0.0144143
USP3 ubiquitin specific peptidase 3 0.0144132
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.0142586
SOX4 SRY (sex determining region Y)-box 4 0.0142276
TRIO trio Rho guanine nucleotide exchange factor 0.0141999
PTPRM protein tyrosine phosphatase, receptor type, M 0.0141609
SUMF1 sulfatase modifying factor 1 0.0140499
CDK14 cyclin-dependent kinase 14 0.0140075
BASP1 brain abundant, membrane attached signal protein 1 0.0139644
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0138938
VEGFC vascular endothelial growth factor C 0.0138681
MAML2 mastermind-like 2 (Drosophila) 0.0137308
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0136174
TRA2A transformer 2 alpha homolog (Drosophila) 0.0134148

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.264321
VIM vimentin -0.14204
IGFBP3 insulin-like growth factor binding protein 3 -0.126035
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.108472
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0992375
LOX lysyl oxidase -0.0867645
FN1 fibronectin 1 -0.086388
FTH1 ferritin, heavy polypeptide 1 -0.0766954
GOLGA4 golgin A4 -0.0703944
CD44 CD44 molecule (Indian blood group) -0.0677896
FTL ferritin, light polypeptide -0.0636947
EIF1 eukaryotic translation initiation factor 1 -0.0566047
RPL35A ribosomal protein L35a -0.0545571
OSMR oncostatin M receptor -0.0493701
RPL31 ribosomal protein L31 -0.0489532
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0473817
RPS6 ribosomal protein S6 -0.0445986
RPS23 ribosomal protein S23 -0.0399742
STC1 stanniocalcin 1 -0.0399687
PTMA prothymosin, alpha -0.0391962
RPS13 ribosomal protein S13 -0.0389236
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0386519
RPS29 ribosomal protein S29 -0.0365032
LMAN1 lectin, mannose-binding, 1 -0.0355578
SEC31A SEC31 homolog A (S. cerevisiae) -0.035001
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0337611
RPS25 ribosomal protein S25 -0.0335028
RAB1A RAB1A, member RAS oncogene family -0.033401
RPLP1 ribosomal protein, large, P1 -0.0332552
S100A10 S100 calcium binding protein A10 -0.0332362
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0325099
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0324515
HM13 histocompatibility (minor) 13 -0.0320439
TMEM165 transmembrane protein 165 -0.0308679
NDRG1 N-myc downstream regulated 1 -0.0307692
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0297094
GLCCI1 glucocorticoid induced 1 -0.0296208
ANKRD28 ankyrin repeat domain 28 -0.0291185
ENO2 enolase 2 (gamma, neuronal) -0.0290718
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0284953
RPL28 ribosomal protein L28 -0.027991
SEPTIN9 septin 9 -0.027976
CDCP1 CUB domain containing protein 1 -0.0278349
RPS11 ribosomal protein S11 -0.0277362
RPS8 ribosomal protein S8 -0.0275574
VDAC1 voltage-dependent anion channel 1 -0.0273404
UBC ubiquitin C -0.0271923
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0271566
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0270571
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0267846
SETD5 SET domain containing 5 -0.0263121
TTC3 tetratricopeptide repeat domain 3 -0.0263081
HIP1 huntingtin interacting protein 1 -0.0262429
RSU1 Ras suppressor protein 1 -0.026134
OPTN optineurin -0.0259942
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.025853
CLIC4 chloride intracellular channel 4 -0.0255092
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0250772
BTG1 B-cell translocation gene 1, anti-proliferative -0.0250485
BPTF bromodomain PHD finger transcription factor -0.025027
S100A6 S100 calcium binding protein A6 -0.0244835
COPB1 coatomer protein complex, subunit beta 1 -0.0243608
RPL7A ribosomal protein L7a -0.0242122
PKM pyruvate kinase, muscle -0.024146
RPL19 ribosomal protein L19 -0.0240036
CALU calumenin -0.0239714
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0235848
PDIA3 protein disulfide isomerase family A, member 3 -0.0235675
CA12 carbonic anhydrase XII -0.0232343
MON2 MON2 homolog (S. cerevisiae) -0.0232196
EGFR epidermal growth factor receptor -0.0231531
RPS27 ribosomal protein S27 -0.023112
PYGL phosphorylase, glycogen, liver -0.0230826
HDLBP high density lipoprotein binding protein -0.0230275
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.0228101
TMSB10 thymosin beta 10 -0.0227373
ATF7 activating transcription factor 7 -0.0225765
RPL37A ribosomal protein L37a -0.0225726
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0224516
RPL11 ribosomal protein L11 -0.0223645
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0221829
RPL32 ribosomal protein L32 -0.0217867
ITCH itchy E3 ubiquitin protein ligase -0.0217747
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0214622
RPS16 ribosomal protein S16 -0.0214549
ENO1 enolase 1, (alpha) -0.0212974
RPL5 ribosomal protein L5 -0.021151
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0210501
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0206435
LOC102724023 ES1 protein homolog, mitochondrial -0.0205567
SEPTIN2 septin 2 -0.0204293
WASF2 WAS protein family, member 2 -0.0204026
CANX calnexin -0.0203464
ARL4C ADP-ribosylation factor-like 4C -0.0203279
EGR1 early growth response 1 -0.0199264
RPL37 ribosomal protein L37 -0.0198148
PCNX4 pecanex 4 -0.0197938
AHI1 Abelson helper integration site 1 -0.0196914
RPS5 ribosomal protein S5 -0.0196606
EEF2 eukaryotic translation elongation factor 2 -0.0196193