Gallic acid (hydrate)_NCI-H2347 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
IGFBP3 insulin-like growth factor binding protein 3 0.10029
TSC22D2 TSC22 domain family, member 2 0.0854263
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.083159
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0545131
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0518139
RNF145 ring finger protein 145 0.0457199
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0400518
FAM13A family with sequence similarity 13, member A 0.034107
UBA6 ubiquitin-like modifier activating enzyme 6 0.0336079
ERRFI1 ERBB receptor feedback inhibitor 1 0.032701
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.0316086
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0312139
USP3 ubiquitin specific peptidase 3 0.028617
MSN moesin 0.0270248
FTH1 ferritin, heavy polypeptide 1 0.0253156
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0252973
CCNL1 cyclin L1 0.0229466
FXR1 fragile X mental retardation, autosomal homolog 1 0.022904
SSBP2 single-stranded DNA binding protein 2 0.0228467
VEGFA vascular endothelial growth factor A 0.0219386
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0219139
ANXA5 annexin A5 0.0210538
UGCG UDP-glucose ceramide glucosyltransferase 0.0199426
DSPP dentin sialophosphoprotein 0.019198
KTN1 kinectin 1 (kinesin receptor) 0.0186298
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0183176
FNBP1L formin binding protein 1-like 0.0181878
ADAM9 ADAM metallopeptidase domain 9 0.0175609
BHLHE40 basic helix-loop-helix family, member e40 0.017219
FOSL1 FOS-like antigen 1 0.0170432
RIOK3 RIO kinase 3 0.0166722
RPS6 ribosomal protein S6 0.0150847
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.0149587
MATR3 matrin 3 0.014837
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0148045
MIER1 mesoderm induction early response 1, transcriptional regulator 0.0144743
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0144554
PDIA3 protein disulfide isomerase family A, member 3 0.0137819
ARRDC3 arrestin domain containing 3 0.0136292
RAD23B RAD23 homolog B (S. cerevisiae) 0.0133845
QKI QKI, KH domain containing, RNA binding 0.0131779
RIPK2 receptor-interacting serine-threonine kinase 2 0.0127425
NUP58 nucleoporin 58 0.012605
KMT2E lysine (K)-specific methyltransferase 2E 0.0120936
HILPDA hypoxia inducible lipid droplet-associated 0.0118
CDK17 cyclin-dependent kinase 17 0.0117979
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0114818
TBC1D12 TBC1 domain family, member 12 0.0112429
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0112374
LRRC58 leucine rich repeat containing 58 0.0110965
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.010999
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0109901
CBX1 chromobox homolog 1 0.0109609
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0108091
KDM1A lysine (K)-specific demethylase 1A 0.0107355
SPAG9 sperm associated antigen 9 0.0107326
MYO1B myosin IB 0.0106637
ZNF292 zinc finger protein 292 0.010603
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0105846
MXI1 MAX interactor 1, dimerization protein 0.0105478
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.0101114
PDIA6 protein disulfide isomerase family A, member 6 0.00992263
RAB18 RAB18, member RAS oncogene family 0.00991679
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.00984796
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 0.0098367
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.00981643
ATG3 autophagy related 3 0.00978469
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0097553
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.00967156
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.0096236
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.00958993
AKAP12 A kinase (PRKA) anchor protein 12 0.00958722
FBXL3 F-box and leucine-rich repeat protein 3 0.00934513
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.00925671
MLF1 myeloid leukemia factor 1 0.00919513
CDC73 cell division cycle 73 0.00918468
FAM162A family with sequence similarity 162, member A 0.00915632
RYBP RING1 and YY1 binding protein 0.00912483
NPEPPS aminopeptidase puromycin sensitive 0.00911714
DST dystonin 0.00903509
CCL28 chemokine (C-C motif) ligand 28 0.00896101
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00890638
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 0.00886422
IPO7 importin 7 0.00884009
RLF rearranged L-myc fusion 0.00880765
FEM1C fem-1 homolog c (C. elegans) 0.00872645
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.00871481
MXD1 MAX dimerization protein 1 0.00868991
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.00867163
TFG TRK-fused gene 0.00862277
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.0085375
LNPK lunapark, ER junction formation factor 0.00850503
PLIN2 perilipin 2 0.0083761
FERMT2 fermitin family member 2 0.00836679
WTAP Wilms tumor 1 associated protein 0.008355
CPNE8 copine VIII 0.00831255
NUB1 negative regulator of ubiquitin-like proteins 1 0.00829445
SCAF4 SR-related CTD-associated factor 4 0.0082577
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.00825596
ARF6 ADP-ribosylation factor 6 0.00821683

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.227572
UBC ubiquitin C -0.167749
FTL ferritin, light polypeptide -0.127925
PTMA prothymosin, alpha -0.112532
TPT1 tumor protein, translationally-controlled 1 -0.10874
EXT1 exostosin glycosyltransferase 1 -0.0947754
POTEF POTE ankyrin domain family, member F -0.0908907
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0840172
ACTG1 actin gamma 1 -0.077705
RPS27A ribosomal protein S27a -0.0768148
S100A6 S100 calcium binding protein A6 -0.0746332
RPL23 ribosomal protein L23 -0.0743675
RPS3 ribosomal protein S3 -0.0742101
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0720693
LPP LIM domain containing preferred translocation partner in lipoma -0.0708066
KRT7 keratin 7, type II -0.0694787
TM4SF1 transmembrane 4 L six family member 1 -0.0650312
SAMD4A sterile alpha motif domain containing 4A -0.0618425
AHNAK AHNAK nucleoprotein -0.0611428
RPL34 ribosomal protein L34 -0.0611142
ERBIN erbb2 interacting protein -0.0590369
IFI6 interferon, alpha-inducible protein 6 -0.0580902
IFI27 interferon, alpha-inducible protein 27 -0.0571871
RPL9 ribosomal protein L9 -0.0570557
RPLP2 ribosomal protein, large, P2 -0.0553661
ASPH aspartate beta-hydroxylase -0.0550206
LAMC2 laminin, gamma 2 -0.0532128
FBXO32 F-box protein 32 -0.0521322
RPL37A ribosomal protein L37a -0.0514939
RPL37 ribosomal protein L37 -0.0500406
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0496281
CALR calreticulin -0.0470329
SEC31A SEC31 homolog A (S. cerevisiae) -0.046538
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0464056
RPS8 ribosomal protein S8 -0.0458903
RACK1 receptor for activated C kinase 1 -0.0452842
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0448455
CCND1 cyclin D1 -0.0434545
HLA-B major histocompatibility complex, class I, B -0.0431716
VCL vinculin -0.0420736
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0418155
RPL19 ribosomal protein L19 -0.0415585
RPS17 ribosomal protein S17 -0.0413976
EIF1 eukaryotic translation initiation factor 1 -0.0413554
RPS19 ribosomal protein S19 -0.0412308
TRIO trio Rho guanine nucleotide exchange factor -0.0410658
HLA-A major histocompatibility complex, class I, A -0.0410151
RAB7A RAB7A, member RAS oncogene family -0.0401206
RPS29 ribosomal protein S29 -0.0399587
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0399397
ALCAM activated leukocyte cell adhesion molecule -0.0396853
LMO7 LIM domain 7 -0.0393894
FLNB filamin B, beta -0.0392578
ENO1 enolase 1, (alpha) -0.039004
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0389771
RPL31 ribosomal protein L31 -0.0386555
LDHA lactate dehydrogenase A -0.0382286
RPS21 ribosomal protein S21 -0.0379935
RPL35A ribosomal protein L35a -0.0375798
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0375406
RPL12 ribosomal protein L12 -0.0374157
RPS24 ribosomal protein S24 -0.0372635
LMNA lamin A/C -0.0370132
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0369177
RPS13 ribosomal protein S13 -0.0365092
ARHGAP5 Rho GTPase activating protein 5 -0.0361592
LAMB3 laminin, beta 3 -0.036098
TPI1 triosephosphate isomerase 1 -0.0360644
SLC38A1 solute carrier family 38, member 1 -0.035953
GOLGA4 golgin A4 -0.0358885
MYO1E myosin IE -0.0358867
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0350144
EPCAM epithelial cell adhesion molecule -0.0349739
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.0347247
BASP1 brain abundant, membrane attached signal protein 1 -0.0346714
WSB1 WD repeat and SOCS box containing 1 -0.034638
UQCRB ubiquinol-cytochrome c reductase binding protein -0.034299
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0339532
DTNA dystrobrevin, alpha -0.0337691
DSCAM Down syndrome cell adhesion molecule -0.0337331
NIPBL Nipped-B homolog (Drosophila) -0.0333978
LOC112694756 uncharaterized LOC112694756 -0.0332891
CALU calumenin -0.0331948
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0328808
RPL15 ribosomal protein L15 -0.0325687
FNIP1 folliculin interacting protein 1 -0.0324468
PLSCR1 phospholipid scramblase 1 -0.0314474
ENO2 enolase 2 (gamma, neuronal) -0.0313706
RCOR1 REST corepressor 1 -0.0309422
ACTN4 actinin, alpha 4 -0.0308076
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0306982
GOLGB1 golgin B1 -0.0306761
SDC4 syndecan 4 -0.0306736
PKM pyruvate kinase, muscle -0.0305642
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.030402
MYO6 myosin VI -0.0303872
SH3KBP1 SH3-domain kinase binding protein 1 -0.0301671
IFITM1 interferon induced transmembrane protein 1 -0.029981
CSNK1A1 casein kinase 1, alpha 1 -0.0294429
BLZF1 basic leucine zipper nuclear factor 1 -0.0293308