Gallic acid (hydrate)_NCI-H460 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in NCI-H460 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ASPH aspartate beta-hydroxylase 0.110274
RPL26 ribosomal protein L26 0.0982814
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0937002
RPL23 ribosomal protein L23 0.0910017
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0901782
TPT1 tumor protein, translationally-controlled 1 0.0877061
RPS12 ribosomal protein S12 0.0864038
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0792112
MT2A metallothionein 2A 0.0765552
NAP1L1 nucleosome assembly protein 1-like 1 0.0763451
PDE4D phosphodiesterase 4D, cAMP-specific 0.0739687
RPL37A ribosomal protein L37a 0.0690968
RPS3 ribosomal protein S3 0.0686214
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0667996
BZW1 basic leucine zipper and W2 domains 1 0.066456
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0629352
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0597362
RGS2 regulator of G-protein signaling 2 0.0585349
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0545468
CXCL8 chemokine (C-X-C motif) ligand 8 0.0543695
RPS27A ribosomal protein S27a 0.0542202
RPS8 ribosomal protein S8 0.0502421
GRAMD1B GRAM domain containing 1B 0.0489841
RPLP1 ribosomal protein, large, P1 0.0484407
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0477309
PRKN parkin RBR E3 ubiquitin protein ligase 0.0476757
PCBP3 poly(rC) binding protein 3 0.0470972
CANX calnexin 0.0465041
ENO1 enolase 1, (alpha) 0.0460129
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0453495
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0448672
PDE10A phosphodiesterase 10A 0.0425379
MYOF myoferlin 0.0420244
RPL31 ribosomal protein L31 0.0415031
NAMPT nicotinamide phosphoribosyltransferase 0.0408839
RPH3AL rabphilin 3A-like (without C2 domains) 0.0402529
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0395243
PGK1 phosphoglycerate kinase 1 0.0389724
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0385598
RAB3B RAB3B, member RAS oncogene family 0.0375884
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0365154
SET SET nuclear proto-oncogene 0.0360455
DGKD diacylglycerol kinase, delta 130kDa 0.0358519
RPS27 ribosomal protein S27 0.0356274
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0348231
RPL36 ribosomal protein L36 0.0343432
RPL9 ribosomal protein L9 0.0340477
YBX3 Y box binding protein 3 0.0330947
EZR ezrin 0.0329724
CENPF centromere protein F, 350/400kDa 0.0317436
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0314951
KTN1 kinectin 1 (kinesin receptor) 0.0314921
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.0305453
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0302685
PYGL phosphorylase, glycogen, liver 0.0302036
PSD3 pleckstrin and Sec7 domain containing 3 0.029669
RPL36A ribosomal protein L36a 0.029422
RPS7 ribosomal protein S7 0.0285106
COL5A2 collagen, type V, alpha 2 0.0277397
RPS2 ribosomal protein S2 0.0276959
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0276326
RPL4 ribosomal protein L4 0.0273065
PRELID2 PRELI domain containing 2 0.027128
RPS17 ribosomal protein S17 0.0267896
RPL27 ribosomal protein L27 0.0262025
HSPA8 heat shock 70kDa protein 8 0.0257867
RPL19 ribosomal protein L19 0.0256138
RPLP0 ribosomal protein, large, P0 0.0255892
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0253922
RPL12 ribosomal protein L12 0.0253279
RPS19 ribosomal protein S19 0.0251087
PDE7B phosphodiesterase 7B 0.0249195
EPHA4 EPH receptor A4 0.0248124
ELL2 elongation factor, RNA polymerase II, 2 0.0247088
RPL10A ribosomal protein L10a 0.0245847
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.0241696
CDK6 cyclin-dependent kinase 6 0.024163
ERRFI1 ERBB receptor feedback inhibitor 1 0.0241553
SH3KBP1 SH3-domain kinase binding protein 1 0.0239522
RPL7 ribosomal protein L7 0.0236854
RPS6 ribosomal protein S6 0.0236443
EIF5B eukaryotic translation initiation factor 5B 0.0231664
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0230282
TPR translocated promoter region, nuclear basket protein 0.0229197
RPL35 ribosomal protein L35 0.0228869
RIGI RNA sensor RIG-I 0.0228008
RACK1 receptor for activated C kinase 1 0.0224673
CAVIN1 caveolae associated protein 1 0.0222672
TGFBR1 transforming growth factor, beta receptor 1 0.0222369
RPL17-C18ORF32 RPL17-C18orf32 readthrough 0.0221818
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0221584
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0221459
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0221286
TNPO1 transportin 1 0.0219041
INHBA inhibin, beta A 0.0218963
TRIO trio Rho guanine nucleotide exchange factor 0.0218297
RPL37 ribosomal protein L37 0.0216215
RPLP2 ribosomal protein, large, P2 0.0215945
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0213933
NT5C2 5'-nucleotidase, cytosolic II 0.0211626

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.310838
FN1 fibronectin 1 -0.0966837
POTEF POTE ankyrin domain family, member F -0.0788784
GDA guanine deaminase -0.0754797
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.074873
FTH1 ferritin, heavy polypeptide 1 -0.0670685
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0613619
FNDC3B fibronectin type III domain containing 3B -0.059031
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0553226
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.0551406
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0549447
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0523578
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0483023
UBC ubiquitin C -0.0455728
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0454774
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0452448
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0445128
PTEN phosphatase and tensin homolog -0.0434524
ATP5F1B ATP synthase F1 subunit beta -0.042355
MCL1 myeloid cell leukemia 1 -0.0417906
CDH13 cadherin 13 -0.0400554
RPS23 ribosomal protein S23 -0.0392906
SMYD3 SET and MYND domain containing 3 -0.0378603
AKAP13 A kinase (PRKA) anchor protein 13 -0.0376982
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0364987
LAMA5 laminin, alpha 5 -0.0351853
FNDC3A fibronectin type III domain containing 3A -0.0345567
PDLIM5 PDZ and LIM domain 5 -0.0339102
AUTS2 autism susceptibility candidate 2 -0.0338081
SMAD2 SMAD family member 2 -0.0327102
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0315017
NALF1 NALCN channel auxiliary factor 1 -0.0314811
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0310226
SPAG9 sperm associated antigen 9 -0.0305062
ACTG1 actin gamma 1 -0.0300442
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0295691
IGFBP3 insulin-like growth factor binding protein 3 -0.0293869
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0289046
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0283544
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0281413
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0277433
PCBP2 poly(rC) binding protein 2 -0.0276543
SLC38A2 solute carrier family 38, member 2 -0.0274065
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.0271772
RAB7A RAB7A, member RAS oncogene family -0.0269636
EGR1 early growth response 1 -0.0263056
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0260473
ASTN2 astrotactin 2 -0.0258984
PKM pyruvate kinase, muscle -0.025771
TBXT T-box transcription factor T -0.0253375
ENO2 enolase 2 (gamma, neuronal) -0.0251449
PFN1 profilin 1 -0.0249751
MAP3K20 mitogen-activated protein kinase kinase kinase 20 -0.0249256
NCOR2 nuclear receptor corepressor 2 -0.0240412
HLA-A major histocompatibility complex, class I, A -0.0240369
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0237721
EXT1 exostosin glycosyltransferase 1 -0.0237156
BSG basigin (Ok blood group) -0.0236811
CREB5 cAMP responsive element binding protein 5 -0.0236221
USP34 ubiquitin specific peptidase 34 -0.0230066
FNIP1 folliculin interacting protein 1 -0.022905
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0228507
WARS1 tryptophanyl-tRNA synthetase 1 -0.0225572
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0220379
MGST1 microsomal glutathione S-transferase 1 -0.0216906
TUBA1B tubulin, alpha 1b -0.0215998
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0213736
RTN4 reticulon 4 -0.0212621
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0212256
ZEB2 zinc finger E-box binding homeobox 2 -0.0211917
HLA-B major histocompatibility complex, class I, B -0.021143
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0210974
VCL vinculin -0.0209295
SMOC1 SPARC related modular calcium binding 1 -0.0209262
UNC5D unc-5 homolog D (C. elegans) -0.0208562
DOCK4 dedicator of cytokinesis 4 -0.0206335
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0206043
SAMD4A sterile alpha motif domain containing 4A -0.0205883
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0204007
ATAD1 ATPase family, AAA domain containing 1 -0.0202867
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0201699
CD44 CD44 molecule (Indian blood group) -0.0201617
JMJD1C jumonji domain containing 1C -0.0201354
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0200694
GSK3B glycogen synthase kinase 3 beta -0.0197993
TMEM165 transmembrane protein 165 -0.0195873
NPAS2 neuronal PAS domain protein 2 -0.0195706
COL4A6 collagen, type IV, alpha 6 -0.0195462
CXXC1 CXXC finger protein 1 -0.0195004
CSRP1 cysteine and glycine-rich protein 1 -0.0194895
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.019276
SETD5 SET domain containing 5 -0.0192133
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -0.0191806
COPA coatomer protein complex, subunit alpha -0.0190349
RBMX RNA binding motif protein, X-linked -0.0190335
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0188748
WASF2 WAS protein family, member 2 -0.0186475
SBF2 SET binding factor 2 -0.0186074
GRB10 growth factor receptor-bound protein 10 -0.0182434
THSD4 thrombospondin, type I, domain containing 4 -0.0181399