Gallic acid (hydrate)_NCI-H596 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.153081
VIM vimentin 0.128081
ASPH aspartate beta-hydroxylase 0.122132
PDE4D phosphodiesterase 4D, cAMP-specific 0.121869
NRG3 neuregulin 3 0.0842686
TMSB10 thymosin beta 10 0.0785494
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0664791
TAS2R14 taste receptor, type 2, member 14 0.0660965
RPL11 ribosomal protein L11 0.0627682
RACK1 receptor for activated C kinase 1 0.0624044
SYT1 synaptotagmin I 0.0582739
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.0574885
COL5A2 collagen, type V, alpha 2 0.0568136
SPTBN1 spectrin, beta, non-erythrocytic 1 0.056183
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0536504
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.0518031
THSD4 thrombospondin, type I, domain containing 4 0.0515326
PDE10A phosphodiesterase 10A 0.0508188
RPL30 ribosomal protein L30 0.0488417
FRMD4A FERM domain containing 4A 0.0484375
TM9SF3 transmembrane 9 superfamily member 3 0.0478083
BPTF bromodomain PHD finger transcription factor 0.0475267
SRRM2 serine/arginine repetitive matrix 2 0.0463273
IFI16 interferon, gamma-inducible protein 16 0.0448653
RPS24 ribosomal protein S24 0.04437
PRELID2 PRELI domain containing 2 0.0443384
NAV1 neuron navigator 1 0.0440684
MAML3 mastermind-like 3 (Drosophila) 0.0439806
MAP1B microtubule-associated protein 1B 0.0433413
NAP1L1 nucleosome assembly protein 1-like 1 0.0432686
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.0426065
RPS19 ribosomal protein S19 0.0406187
RNF213 ring finger protein 213 0.0405419
FAM13A family with sequence similarity 13, member A 0.0405129
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0403883
TPT1 tumor protein, translationally-controlled 1 0.0401798
LMNA lamin A/C 0.0398603
GRB10 growth factor receptor-bound protein 10 0.0388371
EEF2 eukaryotic translation elongation factor 2 0.0388134
VEGFA vascular endothelial growth factor A 0.0385715
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0383608
ANKRD28 ankyrin repeat domain 28 0.0382701
PNISR PNN-interacting serine/arginine-rich protein 0.0381798
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0381372
RSL24D1 ribosomal L24 domain containing 1 0.0376463
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0375625
NALF1 NALCN channel auxiliary factor 1 0.0375252
UBE2K ubiquitin-conjugating enzyme E2K 0.0370786
MON2 MON2 homolog (S. cerevisiae) 0.0368968
ATXN1 ataxin 1 0.0368662
PRSS23 protease, serine, 23 0.0368202
CDH13 cadherin 13 0.0362431
ZCCHC7 zinc finger, CCHC domain containing 7 0.0357413
RPS25 ribosomal protein S25 0.0355278
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0354498
NCOA2 nuclear receptor coactivator 2 0.0352404
SOS1 son of sevenless homolog 1 (Drosophila) 0.0350362
FOXP1 forkhead box P1 0.034867
CALD1 caldesmon 1 0.0346252
DST dystonin 0.0343397
TBC1D22A TBC1 domain family, member 22A 0.0337518
ANKRD11 ankyrin repeat domain 11 0.0337054
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0334476
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0332183
RAB1A RAB1A, member RAS oncogene family 0.0328603
DOCK5 dedicator of cytokinesis 5 0.032786
NSD2 nuclear receptor binding SET domain protein 2 0.0327258
CREBBP CREB binding protein 0.0326924
FBXL7 F-box and leucine-rich repeat protein 7 0.0323902
BRD4 bromodomain containing 4 0.0323135
ATF6 activating transcription factor 6 0.0322934
XPO1 exportin 1 0.0316794
CCSER1 coiled-coil serine-rich protein 1 0.031364
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 0.0311786
S100A6 S100 calcium binding protein A6 0.0311259
DHRSX dehydrogenase/reductase (SDR family) X-linked 0.0308936
TTC17 tetratricopeptide repeat domain 17 0.030623
MEIS2 Meis homeobox 2 0.0305995
RPL37A ribosomal protein L37a 0.0305013
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0303925
TXNRD1 thioredoxin reductase 1 0.0302478
TTC3 tetratricopeptide repeat domain 3 0.0302306
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0299431
GLG1 golgi glycoprotein 1 0.029929
FN1 fibronectin 1 0.0296138
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.0292405
HMGA2 high mobility group AT-hook 2 0.0291726
AHR aryl hydrocarbon receptor 0.029054
ZSWIM6 zinc finger, SWIM-type containing 6 0.0288202
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0287907
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0287704
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0283777
RPS5 ribosomal protein S5 0.0282795
PRRC2C proline-rich coiled-coil 2C 0.0281387
OSMR oncostatin M receptor 0.0277936
NF1 neurofibromin 1 0.0277915
FTH1 ferritin, heavy polypeptide 1 0.0277228
PTPRM protein tyrosine phosphatase, receptor type, M 0.0275191
SPAG9 sperm associated antigen 9 0.0273247
FRMD5 FERM domain containing 5 0.0267898

decreased expression

Symbol Name Standardized Value
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.128105
EGFR epidermal growth factor receptor -0.119018
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0827748
MYO6 myosin VI -0.0812479
CD2AP CD2-associated protein -0.0710092
MYO1D myosin ID -0.0682905
NCOA1 nuclear receptor coactivator 1 -0.0661833
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 -0.0659561
GPC6 glypican 6 -0.0615217
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0576168
TRIO trio Rho guanine nucleotide exchange factor -0.0574857
DLG1 discs, large homolog 1 (Drosophila) -0.0565538
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0556185
TRPS1 trichorhinophalangeal syndrome I -0.0536346
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0526422
PDE8A phosphodiesterase 8A -0.0523735
VMP1 vacuole membrane protein 1 -0.0517533
FHIP1A FHF complex subunit HOOK interacting protein 1A -0.0513623
MARCHF6 membrane associated ring-CH-type finger 6 -0.0511603
PNN pinin, desmosome associated protein -0.0503005
ARHGAP29 Rho GTPase activating protein 29 -0.0500665
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0494548
FOXO3 forkhead box O3 -0.0494355
HDAC9 histone deacetylase 9 -0.0485237
PFN1 profilin 1 -0.0483273
TSC22D2 TSC22 domain family, member 2 -0.0480662
RTN4 reticulon 4 -0.0478452
SLMAP sarcolemma associated protein -0.0471025
KDM3A lysine (K)-specific demethylase 3A -0.0461075
ZNF148 zinc finger protein 148 -0.0459685
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0455286
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0448259
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0444506
MAP4 microtubule-associated protein 4 -0.0440778
COL1A2 collagen, type I, alpha 2 -0.0436229
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0435713
ZFAND3 zinc finger, AN1-type domain 3 -0.0434346
RPL4 ribosomal protein L4 -0.0431748
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0425707
FAT1 FAT atypical cadherin 1 -0.0423362
BCAR3 breast cancer anti-estrogen resistance 3 -0.0420407
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0419685
SNX9 sorting nexin 9 -0.0419037
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0413649
RAB7A RAB7A, member RAS oncogene family -0.0405934
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0405699
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0401879
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0390397
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.039001
PIAS1 protein inhibitor of activated STAT, 1 -0.0384077
ARHGAP32 Rho GTPase activating protein 32 -0.0383044
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -0.0381593
KDM6A lysine (K)-specific demethylase 6A -0.0379044
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0376034
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -0.0372267
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0368371
USP34 ubiquitin specific peptidase 34 -0.0366584
RPL32 ribosomal protein L32 -0.0362568
SYNGAP1 synaptic Ras GTPase activating protein 1 -0.0357714
YBX3 Y box binding protein 3 -0.035616
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0354336
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -0.0350449
KDM4C lysine (K)-specific demethylase 4C -0.0345636
CDC27 cell division cycle 27 -0.0345256
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.0342971
SBF2 SET binding factor 2 -0.0341527
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -0.0341231
ZMYM2 zinc finger, MYM-type 2 -0.0339787
NIPBL Nipped-B homolog (Drosophila) -0.0335579
MYO1E myosin IE -0.0335357
RNF149 ring finger protein 149 -0.0328753
TRA2A transformer 2 alpha homolog (Drosophila) -0.0326726
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.032441
NRIP1 nuclear receptor interacting protein 1 -0.0321633
PATJ PATJ crumbs cell polarity complex component -0.032098
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0318123
PEG10 paternally expressed 10 -0.0317239
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.0316345
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -0.0315833
USP53 ubiquitin specific peptidase 53 -0.0308249
RB1CC1 RB1-inducible coiled-coil 1 -0.0306029
ARID4B AT rich interactive domain 4B (RBP1-like) -0.030584
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0297056
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0296799
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0296347
SLTM SAFB-like, transcription modulator -0.029211
KMT2E lysine (K)-specific methyltransferase 2E -0.029174
SMYD3 SET and MYND domain containing 3 -0.0289855
IQGAP1 IQ motif containing GTPase activating protein 1 -0.0288737
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0278685
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0278434
TPM4 tropomyosin 4 -0.0275746
KCMF1 potassium channel modulatory factor 1 -0.0274894
ARRDC3 arrestin domain containing 3 -0.0273623
RPL8 ribosomal protein L8 -0.0273479
PCBP2 poly(rC) binding protein 2 -0.0267575
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0266096
GOLGA4 golgin A4 -0.026255
NDRG1 N-myc downstream regulated 1 -0.025923
ITPRID2 ITPR interacting domain containing 2 -0.0258013