Gallic acid (hydrate)_PANC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.10614
RPS16 ribosomal protein S16 0.0918377
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0907395
NAP1L1 nucleosome assembly protein 1-like 1 0.0864247
MT2A metallothionein 2A 0.0775676
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0737601
TXNRD1 thioredoxin reductase 1 0.0632095
ERRFI1 ERBB receptor feedback inhibitor 1 0.0623715
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0609678
ASPH aspartate beta-hydroxylase 0.057086
ENO1 enolase 1, (alpha) 0.0564335
OGA O-GlcNAcase 0.0543264
ANXA2 annexin A2 0.0534299
BIRC2 baculoviral IAP repeat containing 2 0.0531207
RPS3 ribosomal protein S3 0.0524649
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0507965
KTN1 kinectin 1 (kinesin receptor) 0.0502852
RPS12 ribosomal protein S12 0.0502793
CANX calnexin 0.0490599
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0478119
SPAG9 sperm associated antigen 9 0.0475417
ZNF292 zinc finger protein 292 0.0473761
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0456429
RPL23 ribosomal protein L23 0.0434845
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0433928
RPLP2 ribosomal protein, large, P2 0.0431968
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0420777
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0412761
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0406082
RPS8 ribosomal protein S8 0.0377356
ANLN anillin, actin binding protein 0.0374286
IPO7 importin 7 0.0369954
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0369603
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.036852
B2M beta-2-microglobulin 0.0367587
RPL26 ribosomal protein L26 0.036646
RPL37A ribosomal protein L37a 0.0361668
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0360558
RPLP0 ribosomal protein, large, P0 0.0358118
CENPF centromere protein F, 350/400kDa 0.0358039
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0355844
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0353732
RPLP1 ribosomal protein, large, P1 0.0347997
PRRC2C proline-rich coiled-coil 2C 0.0347749
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.034709
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0345685
SMAD3 SMAD family member 3 0.0345222
YBX1 Y box binding protein 1 0.0330728
PTMA prothymosin, alpha 0.0327268
AKAP12 A kinase (PRKA) anchor protein 12 0.032595
ARRDC3 arrestin domain containing 3 0.0322249
TRA2A transformer 2 alpha homolog (Drosophila) 0.0322047
NFE2L2 nuclear factor, erythroid 2-like 2 0.0321412
NAMPT nicotinamide phosphoribosyltransferase 0.0321257
SNX14 sorting nexin 14 0.032014
KIF5B kinesin family member 5B 0.0316843
GOLGA4 golgin A4 0.0312471
MATR3 matrin 3 0.0306805
TPT1 tumor protein, translationally-controlled 1 0.0301528
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.030003
JMJD1C jumonji domain containing 1C 0.0297722
SET SET nuclear proto-oncogene 0.0292553
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0292044
RPL12 ribosomal protein L12 0.029123
KDM3A lysine (K)-specific demethylase 3A 0.028482
NIPBL Nipped-B homolog (Drosophila) 0.028434
MKI67 marker of proliferation Ki-67 0.0283638
SERINC1 serine incorporator 1 0.0282805
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0282796
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0281891
TPX2 TPX2, microtubule-associated 0.0279962
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0277987
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0277772
PRELID2 PRELI domain containing 2 0.0275917
RPS25 ribosomal protein S25 0.0275896
TNPO1 transportin 1 0.02737
TPR translocated promoter region, nuclear basket protein 0.0273654
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0269663
SEPTIN7 septin 7 0.0269648
CAVIN1 caveolae associated protein 1 0.0269442
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0266068
PNISR PNN-interacting serine/arginine-rich protein 0.0264879
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.0264538
XPO1 exportin 1 0.0262393
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0260886
MYOF myoferlin 0.0259639
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0258912
HMGB2 high mobility group box 2 0.0258035
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0254709
MYH9 myosin, heavy chain 9, non-muscle 0.0252048
RPL35A ribosomal protein L35a 0.025167
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.024905
CSDE1 cold shock domain containing E1, RNA-binding 0.0248517
PGK1 phosphoglycerate kinase 1 0.024645
CKAP5 cytoskeleton associated protein 5 0.0243921
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0243099
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0240322
RPL36A ribosomal protein L36a 0.0239819
TMEM41B transmembrane protein 41B 0.0239601
CALCOCO2 calcium binding and coiled-coil domain 2 0.0238128

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.174251
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.121553
VCL vinculin -0.112089
EGR1 early growth response 1 -0.0677632
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0653719
THSD4 thrombospondin, type I, domain containing 4 -0.0579666
ACTG1 actin gamma 1 -0.057715
AKT2 v-akt murine thymoma viral oncogene homolog 2 -0.0553126
HSPG2 heparan sulfate proteoglycan 2 -0.0535691
VIM vimentin -0.0529178
EGFR epidermal growth factor receptor -0.049622
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0474162
CTSD cathepsin D -0.0465705
SLC35F3 solute carrier family 35, member F3 -0.0419157
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 -0.0407858
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0396372
MAP1B microtubule-associated protein 1B -0.0363935
ATG7 autophagy related 7 -0.0357474
ACTN4 actinin, alpha 4 -0.0354179
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 -0.0336911
TPM1 tropomyosin 1 (alpha) -0.0332928
POTEF POTE ankyrin domain family, member F -0.0330476
ATP5F1B ATP synthase F1 subunit beta -0.0303331
MCL1 myeloid cell leukemia 1 -0.0299861
ZFP36 ZFP36 ring finger protein -0.0299051
RAB7A RAB7A, member RAS oncogene family -0.0298817
TM4SF1 transmembrane 4 L six family member 1 -0.0293868
HMGA1 high mobility group AT-hook 1 -0.0291237
L1CAM L1 cell adhesion molecule -0.0288129
TNS3 tensin 3 -0.0276489
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0274993
HMGA2 high mobility group AT-hook 2 -0.0268305
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0257608
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0250695
NPAS2 neuronal PAS domain protein 2 -0.0250675
PKM pyruvate kinase, muscle -0.0249915
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0243211
NHSL1 NHS-like 1 -0.024095
FOSL1 FOS-like antigen 1 -0.0238835
SDK1 sidekick cell adhesion molecule 1 -0.0233125
MACF1 microtubule-actin crosslinking factor 1 -0.0232719
UBASH3B ubiquitin associated and SH3 domain containing B -0.0228925
EXT1 exostosin glycosyltransferase 1 -0.0227396
PFN1 profilin 1 -0.0226074
MYO1E myosin IE -0.0219939
FTH1 ferritin, heavy polypeptide 1 -0.0212842
RNF220 ring finger protein 220 -0.0206855
FLNA filamin A, alpha -0.0200784
MSRB3 methionine sulfoxide reductase B3 -0.0194786
EHBP1 EH domain binding protein 1 -0.018933
NCOR2 nuclear receptor corepressor 2 -0.0188185
TRIO trio Rho guanine nucleotide exchange factor -0.0178401
ZNF407 zinc finger protein 407 -0.0174947
VEGFA vascular endothelial growth factor A -0.0174713
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0173
WASF2 WAS protein family, member 2 -0.0172957
CARD18 caspase recruitment domain family, member 18 -0.017242
TAPBP TAP binding protein (tapasin) -0.0171215
MSN moesin -0.0167114
PDLIM5 PDZ and LIM domain 5 -0.0165267
RSU1 Ras suppressor protein 1 -0.0160404
ZMYND8 zinc finger, MYND-type containing 8 -0.0159395
IGF2 insulin-like growth factor 2 -0.0156674
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0155126
LAMA5 laminin, alpha 5 -0.0154649
SYNPO synaptopodin -0.0152465
RASAL2 RAS protein activator like 2 -0.0151706
NUP98 nucleoporin 98kDa -0.0150254
LOC112694756 uncharaterized LOC112694756 -0.0149806
RBMX RNA binding motif protein, X-linked -0.0149388
ASTN2 astrotactin 2 -0.0149323
MYO10 myosin X -0.0148562
SEPTIN9 septin 9 -0.0147712
CMIP c-Maf inducing protein -0.0146728
FBXO27 F-box protein 27 -0.0145211
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0143387
MTCL1 microtubule crosslinking factor 1 -0.0135783
BMAL2 basic helix-loop-helix ARNT like 2 -0.0133411
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.0129192
IARS1 isoleucyl-tRNA synthetase 1 -0.0128544
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0127468
EPC2 enhancer of polycomb homolog 2 (Drosophila) -0.0127438
ANPEP alanyl (membrane) aminopeptidase -0.0127357
MCTP1 multiple C2 domains, transmembrane 1 -0.0125876
KIAA1549L KIAA1549-like -0.0125298
GSE1 Gse1 coiled-coil protein -0.012513
ZDHHC14 zinc finger, DHHC-type containing 14 -0.0125118
FBL fibrillarin -0.0124955
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0123467
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.0122918
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0122331
UBAP2 ubiquitin associated protein 2 -0.0119208
ACTN1 actinin, alpha 1 -0.0118953
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.011803
BRD4 bromodomain containing 4 -0.0117517
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -0.0115338
AGO2 argonaute RISC catalytic component 2 -0.0115098
MDK midkine (neurite growth-promoting factor 2) -0.0114908
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0114495
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0113436