Gallic acid (hydrate)_Panc 03.27 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 0.113955
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0960999
RNF213 ring finger protein 213 0.078791
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0748548
RPL23 ribosomal protein L23 0.073145
ASPH aspartate beta-hydroxylase 0.0726047
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0717223
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0715042
TMSB4X thymosin beta 4, X-linked 0.0695265
SVIL supervillin 0.0685011
MACF1 microtubule-actin crosslinking factor 1 0.0682329
MAML2 mastermind-like 2 (Drosophila) 0.0681877
CD44 CD44 molecule (Indian blood group) 0.066873
TPM4 tropomyosin 4 0.0634733
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0628772
ARHGAP5 Rho GTPase activating protein 5 0.061818
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0616455
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.0548954
FN1 fibronectin 1 0.0538254
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0536916
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0518425
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0512588
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0502665
SYT14 synaptotagmin XIV 0.0501415
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0495037
MX1 MX dynamin-like GTPase 1 0.0491085
ZBTB20 zinc finger and BTB domain containing 20 0.0489964
PTMA prothymosin, alpha 0.0488854
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0474963
LMO7 LIM domain 7 0.0474219
RPS8 ribosomal protein S8 0.0469725
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0465928
RIGI RNA sensor RIG-I 0.046515
SQSTM1 sequestosome 1 0.0463013
RPL37A ribosomal protein L37a 0.0457476
JARID2 jumonji, AT rich interactive domain 2 0.0450105
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.0449309
SP100 SP100 nuclear antigen 0.0448535
RPS3 ribosomal protein S3 0.0448512
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.044693
TXNIP thioredoxin interacting protein 0.0441248
RPS6 ribosomal protein S6 0.0440829
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0433135
INTS6 integrator complex subunit 6 0.0430424
RAD51B RAD51 paralog B 0.0421355
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0420949
LAMA4 laminin, alpha 4 0.0420831
HMGA2 high mobility group AT-hook 2 0.0419452
LPP LIM domain containing preferred translocation partner in lipoma 0.0417284
NAV2 neuron navigator 2 0.0409195
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0406074
IFI27 interferon, alpha-inducible protein 27 0.0402656
FMNL2 formin-like 2 0.0401276
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0397939
RPL35A ribosomal protein L35a 0.0393719
MX2 MX dynamin-like GTPase 2 0.0388766
HDAC9 histone deacetylase 9 0.0385189
MEF2A myocyte enhancer factor 2A 0.0383466
RICTOR RPTOR independent companion of MTOR, complex 2 0.0382578
RPS12 ribosomal protein S12 0.0373399
PLAUR plasminogen activator, urokinase receptor 0.0373194
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0372172
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0371637
RPS19 ribosomal protein S19 0.0368529
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0368255
MAML3 mastermind-like 3 (Drosophila) 0.0362144
SAMD4A sterile alpha motif domain containing 4A 0.0361718
RUNX1 runt-related transcription factor 1 0.0361317
PRELID2 PRELI domain containing 2 0.0359333
BBX bobby sox homolog (Drosophila) 0.0358348
ENO1 enolase 1, (alpha) 0.0356764
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.0355638
SYNE2 spectrin repeat containing, nuclear envelope 2 0.035206
MT2A metallothionein 2A 0.0351313
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0347394
AFDN afadin, adherens junction formation factor 0.0346508
KTN1 kinectin 1 (kinesin receptor) 0.0344319
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0344064
IFI44L interferon-induced protein 44-like 0.0343099
IFIH1 interferon induced with helicase C domain 1 0.034046
BACE2 beta-site APP-cleaving enzyme 2 0.0338077
PLSCR1 phospholipid scramblase 1 0.0337883
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0336317
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0335184
SOX4 SRY (sex determining region Y)-box 4 0.0335039
ATXN1 ataxin 1 0.0333771
IFI44 interferon-induced protein 44 0.0333174
FTL ferritin, light polypeptide 0.0329279
SULF2 sulfatase 2 0.0328838
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0325122
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0325036
ITGA6 integrin, alpha 6 0.0323672
SH3KBP1 SH3-domain kinase binding protein 1 0.032108
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0320188
RPL31 ribosomal protein L31 0.0318638
LAMC2 laminin, gamma 2 0.0317813
ACTG1 actin gamma 1 0.031194
DST dystonin 0.0310146
EPSTI1 epithelial stromal interaction 1 (breast) 0.0309635
DSPP dentin sialophosphoprotein 0.0308742

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.220823
MUC4 mucin 4, cell surface associated -0.0810374
KRT17 keratin 17, type I -0.0612333
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0594949
EGR1 early growth response 1 -0.0451779
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0423352
WWC1 WW and C2 domain containing 1 -0.0407142
LOC112694756 uncharaterized LOC112694756 -0.0393924
ARHGAP29 Rho GTPase activating protein 29 -0.0379125
DIAPH3 diaphanous-related formin 3 -0.0367815
TGM2 transglutaminase 2 -0.0353526
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0349402
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.0324425
ECT2 epithelial cell transforming 2 -0.0323474
FTH1 ferritin, heavy polypeptide 1 -0.0313936
RASAL2 RAS protein activator like 2 -0.0307839
CCNL1 cyclin L1 -0.0306348
POTEF POTE ankyrin domain family, member F -0.0298536
THBS1 thrombospondin 1 -0.0295998
LATS2 large tumor suppressor kinase 2 -0.0276981
TSC22D2 TSC22 domain family, member 2 -0.0272446
NCEH1 neutral cholesterol ester hydrolase 1 -0.0271923
SPAG9 sperm associated antigen 9 -0.0269845
SHROOM3 shroom family member 3 -0.0264524
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0257012
COPA coatomer protein complex, subunit alpha -0.023942
FAM3C family with sequence similarity 3, member C -0.0238714
DLC1 DLC1 Rho GTPase activating protein -0.0236378
UGCG UDP-glucose ceramide glucosyltransferase -0.0228363
TAPBP TAP binding protein (tapasin) -0.0226989
SMC4 structural maintenance of chromosomes 4 -0.0224979
IL1RAP interleukin 1 receptor accessory protein -0.0224247
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0223524
BHLHE40 basic helix-loop-helix family, member e40 -0.0218227
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0214731
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.0209197
TXNRD1 thioredoxin reductase 1 -0.0204951
ATP11B ATPase, class VI, type 11B -0.0204109
MIS18BP1 MIS18 binding protein 1 -0.0203545
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0202825
ATP5F1B ATP synthase F1 subunit beta -0.01997
GOLGA4 golgin A4 -0.0197673
NRIP1 nuclear receptor interacting protein 1 -0.019544
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.0193056
BCAR3 breast cancer anti-estrogen resistance 3 -0.0188307
BRD2 bromodomain containing 2 -0.018768
ANLN anillin, actin binding protein -0.0187075
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0185429
DSCAM Down syndrome cell adhesion molecule -0.0182285
MUC16 mucin 16, cell surface associated -0.0180004
COPB1 coatomer protein complex, subunit beta 1 -0.0178763
ITGB4 integrin, beta 4 -0.0176964
C3 complement component 3 -0.0176601
TFG TRK-fused gene -0.0176564
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0173663
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0173617
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.0172778
OSMR oncostatin M receptor -0.0170133
COBL cordon-bleu WH2 repeat protein -0.0167823
TRA2B transformer 2 beta homolog (Drosophila) -0.0165759
LY6E lymphocyte antigen 6 complex, locus E -0.0164558
DLG1 discs, large homolog 1 (Drosophila) -0.0163507
MATR3 matrin 3 -0.0160873
BCL2L1 BCL2-like 1 -0.0160795
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.016026
CLINT1 clathrin interactor 1 -0.0159962
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) -0.0159801
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -0.015926
PDLIM5 PDZ and LIM domain 5 -0.0157783
RTN4 reticulon 4 -0.0154793
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.015473
MKI67 marker of proliferation Ki-67 -0.015155
ANKRD33B ankyrin repeat domain 33B -0.0147458
FOSL1 FOS-like antigen 1 -0.0146308
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.014626
DENND4A DENN/MADD domain containing 4A -0.014565
RBM33 RNA binding motif protein 33 -0.014471
MAP2K4 mitogen-activated protein kinase kinase 4 -0.0143134
ADGRG6 adhesion G protein-coupled receptor G6 -0.0142558
SEC31A SEC31 homolog A (S. cerevisiae) -0.0142332
IL6ST interleukin 6 signal transducer -0.0140457
ADAM9 ADAM metallopeptidase domain 9 -0.0139089
RBMS2 RNA binding motif, single stranded interacting protein 2 -0.0138771
NDFIP2 Nedd4 family interacting protein 2 -0.0138588
CLTC clathrin, heavy chain (Hc) -0.0138267
FAR1 fatty acyl CoA reductase 1 -0.0138154
NEK7 NIMA-related kinase 7 -0.0135253
KIF18A kinesin family member 18A -0.0135095
ETNK1 ethanolamine kinase 1 -0.013478
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -0.0134648
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0134297
ACTN4 actinin, alpha 4 -0.0132617
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.0131801
FHIP1A FHF complex subunit HOOK interacting protein 1A -0.0130772
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0129671
MARCHF6 membrane associated ring-CH-type finger 6 -0.0129039
STK24 serine/threonine kinase 24 -0.0128973
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.0128956
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0125374
TGFB2 transforming growth factor, beta 2 -0.0124909