Gallic acid (hydrate)_RPMI-7951 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
VIM vimentin 0.0894188
PSD3 pleckstrin and Sec7 domain containing 3 0.061359
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0525161
FAM13A family with sequence similarity 13, member A 0.0483638
CD109 CD109 molecule 0.0422254
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.040372
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0383256
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0383086
KTN1 kinectin 1 (kinesin receptor) 0.0381946
PDIA3 protein disulfide isomerase family A, member 3 0.036342
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0337457
VEGFA vascular endothelial growth factor A 0.0329474
ENO1 enolase 1, (alpha) 0.0327678
AKAP12 A kinase (PRKA) anchor protein 12 0.0319117
CAVIN1 caveolae associated protein 1 0.0317075
RNF24 ring finger protein 24 0.0297725
KMT2E lysine (K)-specific methyltransferase 2E 0.0297545
IGFBP3 insulin-like growth factor binding protein 3 0.029416
CANX calnexin 0.0280393
MSN moesin 0.0278434
MYO1B myosin IB 0.0275822
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0274963
RTN4 reticulon 4 0.0272815
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0272756
CLIP4 CAP-GLY domain containing linker protein family, member 4 0.0267711
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.026156
ANGPTL4 angiopoietin-like 4 0.0252526
TTC3 tetratricopeptide repeat domain 3 0.0252254
HILPDA hypoxia inducible lipid droplet-associated 0.025078
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0245304
ZNF148 zinc finger protein 148 0.0243108
UBA6 ubiquitin-like modifier activating enzyme 6 0.0240625
XPO1 exportin 1 0.0239948
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0237064
FXR1 fragile X mental retardation, autosomal homolog 1 0.0233161
COL1A2 collagen, type I, alpha 2 0.0229019
RPS6 ribosomal protein S6 0.0227939
FOS FBJ murine osteosarcoma viral oncogene homolog 0.0226082
GOLGA4 golgin A4 0.0222982
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0221902
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0221192
GOLGB1 golgin B1 0.021871
TMF1 TATA element modulatory factor 1 0.0216787
SMC4 structural maintenance of chromosomes 4 0.0208078
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0207854
SEC24A SEC24 family member A 0.020692
MYADM myeloid-associated differentiation marker 0.0205223
HELZ helicase with zinc finger 0.0202771
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0200975
MYOF myoferlin 0.0199242
ZNF146 zinc finger protein 146 0.0198963
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.0197602
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 0.0196215
FBXO42 F-box protein 42 0.01957
ARRDC3 arrestin domain containing 3 0.0195486
FBXO32 F-box protein 32 0.0195294
NFE2L1 nuclear factor, erythroid 2-like 1 0.0195047
RAI14 retinoic acid induced 14 0.0194872
PDCD6IP programmed cell death 6 interacting protein 0.0194536
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0194271
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.019389
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0191875
SRP54 signal recognition particle 54kDa 0.0191199
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 0.0189187
ANXA1 annexin A1 0.0188325
DDIT4 DNA-damage-inducible transcript 4 0.0188166
RPS12 ribosomal protein S12 0.0187769
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0186195
ESYT2 extended synaptotagmin-like protein 2 0.0185544
NPEPPS aminopeptidase puromycin sensitive 0.0181656
RAB8B RAB8B, member RAS oncogene family 0.0180654
YEATS2 YEATS domain containing 2 0.018016
MTDH metadherin 0.0179288
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0177916
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0177837
GARS1 glycyl-tRNA synthetase 1 0.0177377
TPM4 tropomyosin 4 0.0175451
ARHGAP12 Rho GTPase activating protein 12 0.0175085
HMGA2 high mobility group AT-hook 2 0.0173823
PKM pyruvate kinase, muscle 0.0173779
SLK STE20-like kinase 0.0173746
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0172992
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0172681
RAB6A RAB6A, member RAS oncogene family 0.0172427
ZEB2 zinc finger E-box binding homeobox 2 0.0171812
LMAN1 lectin, mannose-binding, 1 0.0170066
LARS1 leucyl-tRNA synthetase 1 0.0169311
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0168569
KMT2C lysine (K)-specific methyltransferase 2C 0.0165932
INSIG2 insulin induced gene 2 0.0165255
FNBP4 formin binding protein 4 0.0164266
TPR translocated promoter region, nuclear basket protein 0.0164194
MAP2K1 mitogen-activated protein kinase kinase 1 0.0163828
CENPF centromere protein F, 350/400kDa 0.0161299
FAM162A family with sequence similarity 162, member A 0.0161273
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0160945
TCEA1 transcription elongation factor A (SII), 1 0.0160002
ITCH itchy E3 ubiquitin protein ligase 0.0159723
FGFR1 fibroblast growth factor receptor 1 0.0159399
XRN1 5'-3' exoribonuclease 1 0.0158941

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.229432
COL1A1 collagen, type I, alpha 1 -0.158363
HLA-B major histocompatibility complex, class I, B -0.126848
FN1 fibronectin 1 -0.116553
TMSB10 thymosin beta 10 -0.106421
CDH13 cadherin 13 -0.0925478
FRMD4A FERM domain containing 4A -0.0882198
COL6A2 collagen, type VI, alpha 2 -0.0785057
EXT1 exostosin glycosyltransferase 1 -0.0735808
STC1 stanniocalcin 1 -0.07234
RAB7A RAB7A, member RAS oncogene family -0.0719275
COL6A1 collagen, type VI, alpha 1 -0.0679116
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0614566
HLA-C major histocompatibility complex, class I, C -0.0575356
FNDC3B fibronectin type III domain containing 3B -0.057002
NAV1 neuron navigator 1 -0.0553672
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0550169
CD44 CD44 molecule (Indian blood group) -0.0528275
VCL vinculin -0.0522097
GLIS3 GLIS family zinc finger 3 -0.0498905
POTEF POTE ankyrin domain family, member F -0.049576
TNS3 tensin 3 -0.0469685
HPCAL1 hippocalcin-like 1 -0.0467436
B2M beta-2-microglobulin -0.0450616
INHBA inhibin, beta A -0.0440558
IFI6 interferon, alpha-inducible protein 6 -0.0439568
LPP LIM domain containing preferred translocation partner in lipoma -0.0419718
FAM20C family with sequence similarity 20, member C -0.0417171
PCBP3 poly(rC) binding protein 3 -0.041064
TGFBI transforming growth factor, beta-induced, 68kDa -0.039101
ZNFX1 zinc finger, NFX1-type containing 1 -0.0390934
ACTG1 actin gamma 1 -0.0385094
FTL ferritin, light polypeptide -0.038385
ZEB1 zinc finger E-box binding homeobox 1 -0.0380146
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0372273
H1-0 H1.0 linker histone -0.0367267
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0367008
COL5A3 collagen, type V, alpha 3 -0.0365357
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0363928
COL7A1 collagen, type VII, alpha 1 -0.036348
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.036319
IL1B interleukin 1, beta -0.0363094
APCDD1L adenomatosis polyposis coli down-regulated 1-like -0.0356955
NDRG1 N-myc downstream regulated 1 -0.0350956
PTPRG protein tyrosine phosphatase, receptor type, G -0.0349158
COL4A2 collagen, type IV, alpha 2 -0.0347607
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -0.0337756
TNNC1 troponin C type 1 (slow) -0.0335684
ACTN1 actinin, alpha 1 -0.0334126
CAPZB capping protein (actin filament) muscle Z-line, beta -0.0327204
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0325371
NRP1 neuropilin 1 -0.0325166
FTH1 ferritin, heavy polypeptide 1 -0.0319699
PDLIM5 PDZ and LIM domain 5 -0.0318863
RPS21 ribosomal protein S21 -0.031592
LOC102724023 ES1 protein homolog, mitochondrial -0.0313458
ITGA11 integrin, alpha 11 -0.0310624
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0309314
HLA-A major histocompatibility complex, class I, A -0.0305559
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0303657
SH3RF3 SH3 domain containing ring finger 3 -0.0298097
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0294958
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0293827
TCF12 transcription factor 12 -0.0292348
SP100 SP100 nuclear antigen -0.0289821
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0289221
LOC112694756 uncharaterized LOC112694756 -0.0287614
RRBP1 ribosome binding protein 1 -0.0285108
LARP4B La ribonucleoprotein domain family, member 4B -0.0282163
MMP14 matrix metallopeptidase 14 (membrane-inserted) -0.0278943
PXDN peroxidasin -0.0274162
AHNAK AHNAK nucleoprotein -0.0273793
CEMIP cell migration inducing protein, hyaluronan binding -0.0272617
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -0.0267699
BSG basigin (Ok blood group) -0.0267261
BIRC6 baculoviral IAP repeat containing 6 -0.0267121
TRIP12 thyroid hormone receptor interactor 12 -0.0262185
UBC ubiquitin C -0.0259509
CST3 cystatin C -0.0256138
RIGI RNA sensor RIG-I -0.0253744
EGR1 early growth response 1 -0.0248037
RSU1 Ras suppressor protein 1 -0.0246298
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0245952
GNAS GNAS complex locus -0.0245577
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0245096
ERBIN erbb2 interacting protein -0.0244882
TUBB6 tubulin, beta 6 class V -0.0242934
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0242073
LOXL2 lysyl oxidase-like 2 -0.0241603
RPS19 ribosomal protein S19 -0.0238846
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0238501
TFPI2 tissue factor pathway inhibitor 2 -0.0238379
FBXO11 F-box protein 11 -0.0234214
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0233085
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0232338
KYNU kynureninase -0.023103
FHL2 four and a half LIM domains 2 -0.0230943
ADAM12 ADAM metallopeptidase domain 12 -0.0230347
ATXN1 ataxin 1 -0.0229047
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0227125