Gallic acid (hydrate)_SK-MEL-2 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.163613
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.144326
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.141815
RPL23 ribosomal protein L23 0.0912292
PTMA prothymosin, alpha 0.0878227
RPS3 ribosomal protein S3 0.0874399
VIM vimentin 0.0799437
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.077842
TPT1 tumor protein, translationally-controlled 1 0.0765905
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0703802
DST dystonin 0.068823
NLGN1 neuroligin 1 0.0680647
TMSB10 thymosin beta 10 0.0678039
ASPH aspartate beta-hydroxylase 0.0650969
FMN1 formin 1 0.0642327
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0639221
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0636703
RPL35A ribosomal protein L35a 0.0630189
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0625117
NAP1L1 nucleosome assembly protein 1-like 1 0.0620305
ARHGAP5 Rho GTPase activating protein 5 0.0566258
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0538477
RPS6 ribosomal protein S6 0.0524031
PGK1 phosphoglycerate kinase 1 0.0519467
CANX calnexin 0.0500745
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0477696
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0459557
CENPF centromere protein F, 350/400kDa 0.0459366
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0448307
RPLP1 ribosomal protein, large, P1 0.0443286
RPL12 ribosomal protein L12 0.0421606
FTL ferritin, light polypeptide 0.0420709
RPL37A ribosomal protein L37a 0.0409834
PRRC2C proline-rich coiled-coil 2C 0.0409427
RPL34 ribosomal protein L34 0.0408575
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.0408485
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0400984
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0391556
RPS24 ribosomal protein S24 0.0390178
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.03879
RPS12 ribosomal protein S12 0.0387196
PDE4D phosphodiesterase 4D, cAMP-specific 0.0386336
MT2A metallothionein 2A 0.0376666
B2M beta-2-microglobulin 0.0373123
RPL11 ribosomal protein L11 0.0365803
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0365538
TM4SF1 transmembrane 4 L six family member 1 0.0360628
RAD21 RAD21 homolog (S. pombe) 0.0360019
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0356044
RPL31 ribosomal protein L31 0.0344996
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0341605
CTTN cortactin 0.0339756
IFI16 interferon, gamma-inducible protein 16 0.0337926
RPL26 ribosomal protein L26 0.0331263
GARS1 glycyl-tRNA synthetase 1 0.0326673
LAMP2 lysosomal-associated membrane protein 2 0.0324624
EHBP1 EH domain binding protein 1 0.0318908
RPL36 ribosomal protein L36 0.0315483
RPL32 ribosomal protein L32 0.0313463
RPS19 ribosomal protein S19 0.0311927
ALCAM activated leukocyte cell adhesion molecule 0.0311557
RPS13 ribosomal protein S13 0.0307987
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0307242
DSCAM Down syndrome cell adhesion molecule 0.0307084
RPS21 ribosomal protein S21 0.0305965
AHNAK AHNAK nucleoprotein 0.0305907
RPL36A ribosomal protein L36a 0.0304346
RPS8 ribosomal protein S8 0.0303104
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0296218
CBX3 chromobox homolog 3 0.0294276
RRBP1 ribosome binding protein 1 0.029216
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.0289125
LSAMP limbic system-associated membrane protein 0.0287565
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0281816
ENO1 enolase 1, (alpha) 0.0278264
PTPRM protein tyrosine phosphatase, receptor type, M 0.0276584
KDM3A lysine (K)-specific demethylase 3A 0.0273685
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0273673
EIF1 eukaryotic translation initiation factor 1 0.026799
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0265687
RPS27A ribosomal protein S27a 0.0265555
NF1 neurofibromin 1 0.026141
ZFAND3 zinc finger, AN1-type domain 3 0.0259272
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0254971
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0254582
LRMDA leucine rich melanocyte differentiation associated 0.0253486
NRG3 neuregulin 3 0.0252615
NAMPT nicotinamide phosphoribosyltransferase 0.0250875
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0249148
RPS14 ribosomal protein S14 0.0246864
SERINC1 serine incorporator 1 0.0246265
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.0245998
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0245198
SLC39A11 solute carrier family 39, member 11 0.0244359
CD63 CD63 molecule 0.0242329
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0241322
TPI1 triosephosphate isomerase 1 0.0240588
RPL38 ribosomal protein L38 0.0240541
RACK1 receptor for activated C kinase 1 0.0239369
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0238587

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0760728
POTEF POTE ankyrin domain family, member F -0.0601698
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0515148
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0483622
FN1 fibronectin 1 -0.0469838
NOTCH2 notch 2 -0.0469173
FLNA filamin A, alpha -0.0468772
SREBF2 sterol regulatory element binding transcription factor 2 -0.0466553
CLIP4 CAP-GLY domain containing linker protein family, member 4 -0.040864
LOC112694756 uncharaterized LOC112694756 -0.0386813
NDRG1 N-myc downstream regulated 1 -0.0366443
TENM1 teneurin transmembrane protein 1 -0.0359778
ICAM1 intercellular adhesion molecule 1 -0.035886
MSN moesin -0.0345685
PCBP2 poly(rC) binding protein 2 -0.0343763
PKM pyruvate kinase, muscle -0.0308817
FRMD4A FERM domain containing 4A -0.0306366
EEF2 eukaryotic translation elongation factor 2 -0.0298531
SOX10 SRY (sex determining region Y)-box 10 -0.0296981
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0268912
TAPBP TAP binding protein (tapasin) -0.0251143
HMGA1 high mobility group AT-hook 1 -0.0220637
IGFBP3 insulin-like growth factor binding protein 3 -0.0217839
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0210281
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0196909
KIF5C kinesin family member 5C -0.0195423
CYB5R3 cytochrome b5 reductase 3 -0.0194476
CLEC2D C-type lectin domain family 2, member D -0.0193694
FHIT fragile histidine triad -0.0191388
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0191071
VEGFA vascular endothelial growth factor A -0.0190512
WASF2 WAS protein family, member 2 -0.0190408
MEF2D myocyte enhancer factor 2D -0.0183042
ADAM17 ADAM metallopeptidase domain 17 -0.0174037
GLS2 glutaminase 2 (liver, mitochondrial) -0.0167006
CCNL1 cyclin L1 -0.0159873
TBK1 TANK-binding kinase 1 -0.0155495
MIDEAS mitotic deacetylase associated SANT domain protein -0.0154539
WWOX WW domain containing oxidoreductase -0.0151379
ZMIZ2 zinc finger, MIZ-type containing 2 -0.0150776
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0149581
FOSL1 FOS-like antigen 1 -0.014902
ITGB5 integrin, beta 5 -0.0148549
KMT2D lysine (K)-specific methyltransferase 2D -0.0148219
RHOBTB3 Rho-related BTB domain containing 3 -0.0147809
PEA15 phosphoprotein enriched in astrocytes 15 -0.0146351
VAT1 vesicle amine transport 1 -0.014455
FNDC3B fibronectin type III domain containing 3B -0.014302
AKAP9 A kinase (PRKA) anchor protein 9 -0.014178
EP400 E1A binding protein p400 -0.0139281
ATXN2L ataxin 2-like -0.0138592
KMT2E lysine (K)-specific methyltransferase 2E -0.0138022
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -0.0136697
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0136581
PXDN peroxidasin -0.0133431
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0131171
HELZ helicase with zinc finger -0.0131101
PNPLA8 patatin-like phospholipase domain containing 8 -0.0129889
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0128961
TOB2 transducer of ERBB2, 2 -0.0128628
TP63 tumor protein p63 -0.012801
BRD2 bromodomain containing 2 -0.0127985
GRN granulin -0.012785
INTS1 integrator complex subunit 1 -0.0126026
COPA coatomer protein complex, subunit alpha -0.0125032
CABIN1 calcineurin binding protein 1 -0.0125012
WBP2 WW domain binding protein 2 -0.0124602
SQSTM1 sequestosome 1 -0.0123642
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -0.0123278
KLHL13 kelch-like family member 13 -0.0122517
RARA retinoic acid receptor, alpha -0.0122234
EGR1 early growth response 1 -0.0122161
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -0.0120472
CALD1 caldesmon 1 -0.0119702
TSC22D2 TSC22 domain family, member 2 -0.0119023
GTPBP1 GTP binding protein 1 -0.0116064
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0114072
BAG6 BCL2-associated athanogene 6 -0.0113414
RNPS1 RNA binding protein S1, serine-rich domain -0.0112293
TMEM67 transmembrane protein 67 -0.0111552
RNF145 ring finger protein 145 -0.0111231
GPR137B G protein-coupled receptor 137B -0.0111148
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.0109468
UBA1 ubiquitin-like modifier activating enzyme 1 -0.0109266
NRDC nardilysin convertase -0.0108656
SPRY4 sprouty homolog 4 (Drosophila) -0.0107692
CD68 CD68 molecule -0.0107634
RBM28 RNA binding motif protein 28 -0.0107589
ZNF292 zinc finger protein 292 -0.0106747
NSUN6 NOP2/Sun domain family, member 6 -0.0106158
GGNBP2 gametogenetin binding protein 2 -0.0105576
ATN1 atrophin 1 -0.0104009
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.0102811
ESYT2 extended synaptotagmin-like protein 2 -0.0102708
POM121C POM121 transmembrane nucleoporin C -0.0102463
TLN1 talin 1 -0.0102082
TUBA1A tubulin, alpha 1a -0.0101954
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.0101878
SHISA5 shisa family member 5 -0.0100611
PHF14 PHD finger protein 14 -0.00998838