Gallic acid (hydrate)_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.167187
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.113799
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.10039
TMSB4X thymosin beta 4, X-linked 0.0981342
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0807605
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0712972
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0705265
ZNF292 zinc finger protein 292 0.0665894
KDM3A lysine (K)-specific demethylase 3A 0.0653112
ADAM10 ADAM metallopeptidase domain 10 0.059553
NAMPT nicotinamide phosphoribosyltransferase 0.0540785
GOLGA4 golgin A4 0.0534299
RTN4 reticulon 4 0.0511902
QKI QKI, KH domain containing, RNA binding 0.0506984
PGK1 phosphoglycerate kinase 1 0.0492734
RBM39 RNA binding motif protein 39 0.048226
KMT2E lysine (K)-specific methyltransferase 2E 0.0461874
DSCAM Down syndrome cell adhesion molecule 0.0460172
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.045022
ZFAND3 zinc finger, AN1-type domain 3 0.0445989
RNF145 ring finger protein 145 0.0428312
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.042095
EZR ezrin 0.041994
CDC73 cell division cycle 73 0.0416322
RLF rearranged L-myc fusion 0.0391949
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0385158
GARS1 glycyl-tRNA synthetase 1 0.0378926
AHNAK AHNAK nucleoprotein 0.0371153
S100A6 S100 calcium binding protein A6 0.0369395
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.035791
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0356945
TXNIP thioredoxin interacting protein 0.0347245
EIF4A2 eukaryotic translation initiation factor 4A2 0.0347189
NCKAP1 NCK-associated protein 1 0.033946
TFG TRK-fused gene 0.0337494
LOC112694756 uncharaterized LOC112694756 0.0333162
EXT1 exostosin glycosyltransferase 1 0.0327398
LDHA lactate dehydrogenase A 0.0317225
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0315855
PNISR PNN-interacting serine/arginine-rich protein 0.0309378
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0306086
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0304728
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0296859
SSBP2 single-stranded DNA binding protein 2 0.0296082
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.0293267
FBXO11 F-box protein 11 0.0290896
TMEM41B transmembrane protein 41B 0.0290274
NBAS neuroblastoma amplified sequence 0.0288132
OGA O-GlcNAcase 0.0288126
TOP2B topoisomerase (DNA) II beta 180kDa 0.0285678
USP3 ubiquitin specific peptidase 3 0.0284946
ECT2 epithelial cell transforming 2 0.0283943
NCOR1 nuclear receptor corepressor 1 0.0280033
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0276546
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0272986
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0272944
ADAM9 ADAM metallopeptidase domain 9 0.0272455
MATR3 matrin 3 0.0272086
TRA2A transformer 2 alpha homolog (Drosophila) 0.027109
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0266807
NUP58 nucleoporin 58 0.0265653
PTBP2 polypyrimidine tract binding protein 2 0.0265118
RAD21 RAD21 homolog (S. pombe) 0.0262169
PUM2 pumilio RNA-binding family member 2 0.0259863
COG5 component of oligomeric golgi complex 5 0.0258702
MARCHF6 membrane associated ring-CH-type finger 6 0.0252618
SMNDC1 survival motor neuron domain containing 1 0.0250236
ANK2 ankyrin 2, neuronal 0.0249517
EML4 echinoderm microtubule associated protein like 4 0.0247573
WAC WW domain containing adaptor with coiled-coil 0.0247444
XPO1 exportin 1 0.0244605
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0243239
RAB1A RAB1A, member RAS oncogene family 0.0243077
SPAG9 sperm associated antigen 9 0.0242535
TOP1 topoisomerase (DNA) I 0.0241758
RSRC2 arginine/serine-rich coiled-coil 2 0.024167
KMT2C lysine (K)-specific methyltransferase 2C 0.0241612
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0238816
SQSTM1 sequestosome 1 0.0238786
B2M beta-2-microglobulin 0.0238747
YTHDC1 YTH domain containing 1 0.0238429
PICALM phosphatidylinositol binding clathrin assembly protein 0.0237856
HELZ helicase with zinc finger 0.0232067
ZCCHC7 zinc finger, CCHC domain containing 7 0.0231808
SLMAP sarcolemma associated protein 0.0231069
FXR1 fragile X mental retardation, autosomal homolog 1 0.0231033
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0230654
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0227227
EIF1 eukaryotic translation initiation factor 1 0.022563
ELOVL5 ELOVL fatty acid elongase 5 0.0225527
CCNL1 cyclin L1 0.0223852
WSB1 WD repeat and SOCS box containing 1 0.0223545
MORF4L2 mortality factor 4 like 2 0.0223516
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0222371
NIPBL Nipped-B homolog (Drosophila) 0.0221185
YME1L1 YME1-like 1 ATPase 0.0218357
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0217203
DDIT4 DNA-damage-inducible transcript 4 0.0216659
TXNRD1 thioredoxin reductase 1 0.0216138
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.0214881

decreased expression

Symbol Name Standardized Value
PDE4B phosphodiesterase 4B, cAMP-specific -0.137538
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.13445
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.10271
FOXP1 forkhead box P1 -0.0741475
BMP10 bone morphogenetic protein 10 -0.0732625
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0659268
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.060877
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0458734
GLI3 GLI family zinc finger 3 -0.0394824
EGFR epidermal growth factor receptor -0.0382389
DIAPH3 diaphanous-related formin 3 -0.0340993
POTEF POTE ankyrin domain family, member F -0.0338488
CCND1 cyclin D1 -0.0330941
NBEA neurobeachin -0.0330284
VCL vinculin -0.032038
GSE1 Gse1 coiled-coil protein -0.0308561
DLG1 discs, large homolog 1 (Drosophila) -0.0306607
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0300963
TTC28 tetratricopeptide repeat domain 28 -0.0300418
DPYD dihydropyrimidine dehydrogenase -0.0298935
EBNA1BP2 EBNA1 binding protein 2 -0.029822
RPS8 ribosomal protein S8 -0.0297004
MKI67 marker of proliferation Ki-67 -0.029588
NPAS2 neuronal PAS domain protein 2 -0.0294057
RFC3 replication factor C (activator 1) 3, 38kDa -0.028919
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0280473
SOX6 SRY (sex determining region Y)-box 6 -0.0275544
SMC4 structural maintenance of chromosomes 4 -0.0273682
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0273069
RPL9 ribosomal protein L9 -0.0273065
TOP2A topoisomerase (DNA) II alpha 170kDa -0.027064
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.0262358
UNC13A unc-13 homolog A (C. elegans) -0.0252589
PDE7B phosphodiesterase 7B -0.0248686
TPT1 tumor protein, translationally-controlled 1 -0.024608
IGF2 insulin-like growth factor 2 -0.024345
TUBA1B tubulin, alpha 1b -0.0242278
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0240858
CAMKMT calmodulin-lysine N-methyltransferase -0.024083
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0235658
ZMYND8 zinc finger, MYND-type containing 8 -0.0231497
ENO2 enolase 2 (gamma, neuronal) -0.0230899
GLI2 GLI family zinc finger 2 -0.0230348
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0230305
RPL35A ribosomal protein L35a -0.0221151
TUBB4B tubulin, beta 4B class IVb -0.022015
LOC102724023 ES1 protein homolog, mitochondrial -0.0217998
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.0216671
CENPF centromere protein F, 350/400kDa -0.0214537
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0214261
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0205553
PATJ PATJ crumbs cell polarity complex component -0.0203456
FER1L6 fer-1-like family member 6 -0.019768
AEBP2 AE binding protein 2 -0.0193191
ASPH aspartate beta-hydroxylase -0.0193089
CUX1 cut-like homeobox 1 -0.0192988
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0184415
RPL31 ribosomal protein L31 -0.0177647
TSC22D1 TSC22 domain family, member 1 -0.0177581
INTS6 integrator complex subunit 6 -0.0176893
TJP1 tight junction protein 1 -0.0176842
MYL12B myosin, light chain 12B, regulatory -0.0174522
RPL37A ribosomal protein L37a -0.0170092
KLF3 Kruppel-like factor 3 (basic) -0.0168987
HSPB1 heat shock 27kDa protein 1 -0.0168854
HEG1 heart development protein with EGF-like domains 1 -0.0168428
S100A4 S100 calcium binding protein A4 -0.0168412
TBCA tubulin folding cofactor A -0.0167291
PRUNE2 prune homolog 2 (Drosophila) -0.0165183
SEPTIN9 septin 9 -0.0156606
TOB1 transducer of ERBB2, 1 -0.0154861
ARHGAP25 Rho GTPase activating protein 25 -0.0154304
PKP4 plakophilin 4 -0.0154289
TAS2R14 taste receptor, type 2, member 14 -0.0152932
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0151769
PCNX4 pecanex 4 -0.0151549
ZNF438 zinc finger protein 438 -0.0148142
COMMD10 COMM domain containing 10 -0.0147753
FHIT fragile histidine triad -0.0147229
MLIP muscular LMNA-interacting protein -0.0147044
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0140733
ATAD2 ATPase family, AAA domain containing 2 -0.013995
ONECUT2 one cut homeobox 2 -0.0139425
TPI1 triosephosphate isomerase 1 -0.0137368
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0136762
SLC38A2 solute carrier family 38, member 2 -0.0136373
RAD51B RAD51 paralog B -0.0135609
TUBB tubulin, beta class I -0.0134736
ITGA10 integrin, alpha 10 -0.0134125
VIM vimentin -0.0133808
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0133702
NAV2 neuron navigator 2 -0.0133079
PLXNA2 plexin A2 -0.0131547
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -0.0131516
SMIM44 small integral membrane protein 44 -0.0131207
PTPRF protein tyrosine phosphatase, receptor type, F -0.0130368
RRM2 ribonucleotide reductase M2 -0.0128622
ARL4C ADP-ribosylation factor-like 4C -0.012834
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0127456
RPS3 ribosomal protein S3 -0.0127192