Gallic acid (hydrate)_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0928605
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0513923
MYH9 myosin, heavy chain 9, non-muscle 0.0376397
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0375703
NAV2 neuron navigator 2 0.0369679
RPS6 ribosomal protein S6 0.0347593
EEF2 eukaryotic translation elongation factor 2 0.033754
ARRDC3 arrestin domain containing 3 0.0274873
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0262894
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0262537
RPL23 ribosomal protein L23 0.0251623
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.024742
APLP2 amyloid beta (A4) precursor-like protein 2 0.0223431
ZNF292 zinc finger protein 292 0.0222438
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0213631
CENPF centromere protein F, 350/400kDa 0.0198909
OPTN optineurin 0.018789
OGA O-GlcNAcase 0.0186468
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0185512
TNIP1 TNFAIP3 interacting protein 1 0.0185357
MSN moesin 0.0184011
MKI67 marker of proliferation Ki-67 0.0177339
RPS12 ribosomal protein S12 0.0173907
ERRFI1 ERBB receptor feedback inhibitor 1 0.017181
AKAP12 A kinase (PRKA) anchor protein 12 0.0166668
YBX1 Y box binding protein 1 0.0165979
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0162422
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0159578
MATR3 matrin 3 0.0157232
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0144514
RPS8 ribosomal protein S8 0.0144379
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.014329
TPM3 tropomyosin 3 0.0141971
VEGFA vascular endothelial growth factor A 0.0141192
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0135148
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0134709
EIF4B eukaryotic translation initiation factor 4B 0.01339
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0133517
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0133234
CEP250 centrosomal protein 250kDa 0.0131618
PDIA3 protein disulfide isomerase family A, member 3 0.0130778
UBA6 ubiquitin-like modifier activating enzyme 6 0.0128901
KTN1 kinectin 1 (kinesin receptor) 0.0124755
SPAG9 sperm associated antigen 9 0.0118566
HDAC9 histone deacetylase 9 0.0118385
ANLN anillin, actin binding protein 0.0117934
SERINC1 serine incorporator 1 0.0115972
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0115582
SLK STE20-like kinase 0.0115224
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0114258
ANKRD36 ankyrin repeat domain 36 0.01121
MBNL2 muscleblind-like splicing regulator 2 0.0111901
SET SET nuclear proto-oncogene 0.0109692
CANX calnexin 0.0108002
XPO1 exportin 1 0.0106388
NONO non-POU domain containing, octamer-binding 0.0106344
ESYT2 extended synaptotagmin-like protein 2 0.0105927
ELL2 elongation factor, RNA polymerase II, 2 0.0105657
RPS2 ribosomal protein S2 0.010451
RPL3 ribosomal protein L3 0.010241
SMC3 structural maintenance of chromosomes 3 0.0102132
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0101814
RPL10A ribosomal protein L10a 0.0101182
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0100713
PPP1R12B protein phosphatase 1, regulatory subunit 12B 0.0100659
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.00998956
ZNF608 zinc finger protein 608 0.00997511
TMF1 TATA element modulatory factor 1 0.00988276
TPX2 TPX2, microtubule-associated 0.00979394
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.00974279
GOLGA4 golgin A4 0.00968877
PDCD6IP programmed cell death 6 interacting protein 0.0096139
FAM13A family with sequence similarity 13, member A 0.00959003
HSPA8 heat shock 70kDa protein 8 0.00951691
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.00942433
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.00925187
EZR ezrin 0.00923727
NFE2L1 nuclear factor, erythroid 2-like 1 0.0090845
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0090218
ANXA1 annexin A1 0.00902163
BHLHE40 basic helix-loop-helix family, member e40 0.00895682
EGLN1 egl-9 family hypoxia-inducible factor 1 0.00885142
ENO1 enolase 1, (alpha) 0.00883458
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00876654
PDIA6 protein disulfide isomerase family A, member 6 0.00867973
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 0.0085979
USP47 ubiquitin specific peptidase 47 0.0085687
DSPP dentin sialophosphoprotein 0.00856051
MYOF myoferlin 0.00847868
DHFR dihydrofolate reductase 0.00847802
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00845117
AKAP13 A kinase (PRKA) anchor protein 13 0.0083423
RPL4 ribosomal protein L4 0.0083349
MYO1B myosin IB 0.00823603
PAIP2 poly(A) binding protein interacting protein 2 0.00807084
PABPC1 poly(A) binding protein, cytoplasmic 1 0.00804367
KMT2E lysine (K)-specific methyltransferase 2E 0.00791351
MTDH metadherin 0.00790642
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.00790175
CKAP5 cytoskeleton associated protein 5 0.00786324

decreased expression

Symbol Name Standardized Value
GLIS3 GLIS family zinc finger 3 -0.141402
FN1 fibronectin 1 -0.11591
VIM vimentin -0.0891122
FRMD4A FERM domain containing 4A -0.0869811
EXT1 exostosin glycosyltransferase 1 -0.081287
SOD2 superoxide dismutase 2, mitochondrial -0.0778615
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0744707
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0699648
IER3 immediate early response 3 -0.0673253
COL6A3 collagen, type VI, alpha 3 -0.0631396
ZMYND8 zinc finger, MYND-type containing 8 -0.0612299
HMGA2 high mobility group AT-hook 2 -0.0589098
BICC1 BicC family RNA binding protein 1 -0.0583045
HLA-B major histocompatibility complex, class I, B -0.0566373
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0538992
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0536993
VCL vinculin -0.0532014
IGFBP3 insulin-like growth factor binding protein 3 -0.0520453
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.0517682
TMSB10 thymosin beta 10 -0.0496933
NDRG1 N-myc downstream regulated 1 -0.0486872
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0459473
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.0435487
NAMPT nicotinamide phosphoribosyltransferase -0.0427172
CTSD cathepsin D -0.0425743
RAI14 retinoic acid induced 14 -0.0424422
TPT1 tumor protein, translationally-controlled 1 -0.0403407
C3 complement component 3 -0.0400993
EGR1 early growth response 1 -0.0399065
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0386425
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0378343
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.036958
CDH13 cadherin 13 -0.0359333
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -0.0358977
COL1A1 collagen, type I, alpha 1 -0.0353087
EDIL3 EGF-like repeats and discoidin I-like domains 3 -0.0352827
CD44 CD44 molecule (Indian blood group) -0.0348561
TGFBI transforming growth factor, beta-induced, 68kDa -0.0327201
ADAM12 ADAM metallopeptidase domain 12 -0.0326822
DIAPH2 diaphanous-related formin 2 -0.0316497
FTL ferritin, light polypeptide -0.0315434
COL5A1 collagen, type V, alpha 1 -0.0312264
AHNAK AHNAK nucleoprotein -0.0303375
NAV1 neuron navigator 1 -0.0301449
SFRP1 secreted frizzled-related protein 1 -0.0300622
ZBTB20 zinc finger and BTB domain containing 20 -0.0296041
MAML2 mastermind-like 2 (Drosophila) -0.0293867
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0291801
FNDC3B fibronectin type III domain containing 3B -0.0287449
HLA-A major histocompatibility complex, class I, A -0.0286163
PDE10A phosphodiesterase 10A -0.0284591
BASP1 brain abundant, membrane attached signal protein 1 -0.0283189
SLC38A2 solute carrier family 38, member 2 -0.0282223
LOX lysyl oxidase -0.0272446
SFTPA2 surfactant protein A2 -0.0271742
CLMP CXADR-like membrane protein -0.0270666
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0268134
DST dystonin -0.0267012
NABP1 nucleic acid binding protein 1 -0.0265118
TNS3 tensin 3 -0.0265016
THBS1 thrombospondin 1 -0.0263977
RNF213 ring finger protein 213 -0.0260413
SOX5 SRY (sex determining region Y)-box 5 -0.0253577
PTPRK protein tyrosine phosphatase, receptor type, K -0.0250529
CTSB cathepsin B -0.0248815
IFI6 interferon, alpha-inducible protein 6 -0.0244984
TUBB tubulin, beta class I -0.023756
CADM1 cell adhesion molecule 1 -0.0236285
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0235125
SLC38A1 solute carrier family 38, member 1 -0.023377
EGFR epidermal growth factor receptor -0.0233526
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0231199
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.023088
LPP LIM domain containing preferred translocation partner in lipoma -0.0227233
BNC2 basonuclin 2 -0.022626
FAM20C family with sequence similarity 20, member C -0.0225704
TMEM132D transmembrane protein 132D -0.0222381
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0219194
TPM1 tropomyosin 1 (alpha) -0.0218268
GNAS GNAS complex locus -0.0216379
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0216031
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0214364
HMGA1 high mobility group AT-hook 1 -0.0213891
SMAD3 SMAD family member 3 -0.0213317
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0213177
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0212303
PHF21A PHD finger protein 21A -0.0210455
SAMD3 sterile alpha motif domain containing 3 -0.020538
DPYD dihydropyrimidine dehydrogenase -0.0204363
KLF12 Kruppel-like factor 12 -0.0203751
SDK1 sidekick cell adhesion molecule 1 -0.0203725
NRP1 neuropilin 1 -0.0203451
TENM2 teneurin transmembrane protein 2 -0.0199914
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0197891
KRT19 keratin 19, type I -0.0196942
THBS2 thrombospondin 2 -0.019672
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0196164
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0193298
ZFAND3 zinc finger, AN1-type domain 3 -0.0192328
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -0.0191302