Gallic acid (hydrate)_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.106684
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.079942
MT2A metallothionein 2A 0.0794437
ERRFI1 ERBB receptor feedback inhibitor 1 0.0783283
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0711671
VIM vimentin 0.0613035
FAM13A family with sequence similarity 13, member A 0.0592018
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 0.0563243
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0518776
ATP13A3 ATPase type 13A3 0.0503886
TMEM165 transmembrane protein 165 0.0476788
AKAP12 A kinase (PRKA) anchor protein 12 0.0472058
EGFR epidermal growth factor receptor 0.0437841
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0421279
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0418494
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0414065
INSIG2 insulin induced gene 2 0.0410012
COPB1 coatomer protein complex, subunit beta 1 0.0399334
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0393974
AKAP9 A kinase (PRKA) anchor protein 9 0.0385603
SEC24A SEC24 family member A 0.0383899
RPL37A ribosomal protein L37a 0.0361564
VMP1 vacuole membrane protein 1 0.0359067
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0358081
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0349246
CALD1 caldesmon 1 0.0343332
FNDC3A fibronectin type III domain containing 3A 0.034301
SND1 staphylococcal nuclease and tudor domain containing 1 0.0342945
PDIA3 protein disulfide isomerase family A, member 3 0.0336331
ZSWIM6 zinc finger, SWIM-type containing 6 0.0325373
UBA6 ubiquitin-like modifier activating enzyme 6 0.0324699
CDH13 cadherin 13 0.0324025
STC1 stanniocalcin 1 0.0311499
UGCG UDP-glucose ceramide glucosyltransferase 0.0304703
LIMS1 LIM and senescent cell antigen-like domains 1 0.0302577
SAMD4A sterile alpha motif domain containing 4A 0.0299167
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0297609
RPS8 ribosomal protein S8 0.0296533
ZFAND3 zinc finger, AN1-type domain 3 0.0294594
SEC24D SEC24 family member D 0.0291068
NAMPT nicotinamide phosphoribosyltransferase 0.0289747
NRXN3 neurexin 3 0.028585
HILPDA hypoxia inducible lipid droplet-associated 0.0280735
EHBP1 EH domain binding protein 1 0.0280451
HELZ helicase with zinc finger 0.0279842
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.027864
ANKRD11 ankyrin repeat domain 11 0.0278332
PDLIM5 PDZ and LIM domain 5 0.0277333
RAB8B RAB8B, member RAS oncogene family 0.027705
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0276726
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0275013
INTS6 integrator complex subunit 6 0.0273324
PGM3 phosphoglucomutase 3 0.0271887
HIP1 huntingtin interacting protein 1 0.0271783
CXCL8 chemokine (C-X-C motif) ligand 8 0.0264771
MBNL2 muscleblind-like splicing regulator 2 0.0257483
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.0257449
RND3 Rho family GTPase 3 0.0255581
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0251508
BACE2 beta-site APP-cleaving enzyme 2 0.0247277
SOCS5 suppressor of cytokine signaling 5 0.0245327
TENT2 terminal nucleotidyltransferase 2 0.0244704
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0244389
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 0.0243142
PTPRM protein tyrosine phosphatase, receptor type, M 0.0243071
CA12 carbonic anhydrase XII 0.0242359
ZNF207 zinc finger protein 207 0.024114
NAP1L1 nucleosome assembly protein 1-like 1 0.0237544
UBN2 ubinuclein 2 0.0237498
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0234789
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 0.0233043
ARHGAP24 Rho GTPase activating protein 24 0.0233041
ASPH aspartate beta-hydroxylase 0.0233007
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0232504
CNOT8 CCR4-NOT transcription complex, subunit 8 0.0232262
NCOR1 nuclear receptor corepressor 1 0.0230733
HDAC9 histone deacetylase 9 0.0229625
BHLHE40 basic helix-loop-helix family, member e40 0.0229353
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0226311
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0225652
SPAG9 sperm associated antigen 9 0.0223566
YEATS2 YEATS domain containing 2 0.0223183
NUDCD3 NudC domain containing 3 0.0223076
RPS27 ribosomal protein S27 0.022236
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.0222021
UBE2H ubiquitin-conjugating enzyme E2H 0.022179
RAB10 RAB10, member RAS oncogene family 0.022126
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0220332
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.0219784
VEGFC vascular endothelial growth factor C 0.0218607
GLG1 golgi glycoprotein 1 0.0218375
USP47 ubiquitin specific peptidase 47 0.0217915
RAP1A RAP1A, member of RAS oncogene family 0.0217867
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0216928
GARS1 glycyl-tRNA synthetase 1 0.0216493
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0215673
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0215501
GOLGA4 golgin A4 0.0215351
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0214636
AGO3 argonaute RISC catalytic component 3 0.021335

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.327228
FN1 fibronectin 1 -0.169534
COL1A1 collagen, type I, alpha 1 -0.12092
TGFBI transforming growth factor, beta-induced, 68kDa -0.108755
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.102517
COL6A3 collagen, type VI, alpha 3 -0.100152
IGFBP3 insulin-like growth factor binding protein 3 -0.093926
ACTG1 actin gamma 1 -0.0645999
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0632379
COL6A1 collagen, type VI, alpha 1 -0.0568344
LDHA lactate dehydrogenase A -0.0510825
CCNI cyclin I -0.0507305
EGR1 early growth response 1 -0.0488724
POTEF POTE ankyrin domain family, member F -0.0479354
AHNAK AHNAK nucleoprotein -0.0472014
TNS3 tensin 3 -0.0471012
CALR calreticulin -0.0468634
COL1A2 collagen, type I, alpha 2 -0.0445924
PSD3 pleckstrin and Sec7 domain containing 3 -0.0442137
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0440446
PKM pyruvate kinase, muscle -0.0439104
MAP1B microtubule-associated protein 1B -0.041488
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0401241
TUBB tubulin, beta class I -0.0395235
TANK TRAF family member-associated NFKB activator -0.0378089
FTH1 ferritin, heavy polypeptide 1 -0.0363848
HMGB1 high mobility group box 1 -0.036283
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.0352086
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0346571
EFNA5 ephrin-A5 -0.0345163
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -0.0343167
LOX lysyl oxidase -0.0340786
SMAD3 SMAD family member 3 -0.0339138
TNNC1 troponin C type 1 (slow) -0.0330773
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0328648
HMGA2 high mobility group AT-hook 2 -0.0321889
PDE4D phosphodiesterase 4D, cAMP-specific -0.0315495
COL5A1 collagen, type V, alpha 1 -0.0313468
RPL34 ribosomal protein L34 -0.0311042
H3-3B H3.3 histone B -0.0310729
SREBF2 sterol regulatory element binding transcription factor 2 -0.0310495
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0310487
RPL28 ribosomal protein L28 -0.0305106
MMP2 matrix metallopeptidase 2 -0.0303812
LPP LIM domain containing preferred translocation partner in lipoma -0.029829
MAML2 mastermind-like 2 (Drosophila) -0.0297433
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -0.0294435
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -0.0292171
VDAC1 voltage-dependent anion channel 1 -0.0289123
ESYT2 extended synaptotagmin-like protein 2 -0.0287919
HLA-B major histocompatibility complex, class I, B -0.0286672
CST3 cystatin C -0.0282849
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0281511
COL5A2 collagen, type V, alpha 2 -0.0279634
NCOA7 nuclear receptor coactivator 7 -0.0275311
NCOR2 nuclear receptor corepressor 2 -0.0274905
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0274641
LOXL2 lysyl oxidase-like 2 -0.0270881
TNRC6B trinucleotide repeat containing 6B -0.0270403
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0270115
PIAS1 protein inhibitor of activated STAT, 1 -0.026993
ELP4 elongator acetyltransferase complex subunit 4 -0.0268662
EFHD2 EF-hand domain family, member D2 -0.0267433
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0265879
FTL ferritin, light polypeptide -0.0262692
AFF3 AF4/FMR2 family, member 3 -0.0261462
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0261371
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.025996
AK1 adenylate kinase 1 -0.0258822
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0254573
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0254014
AFAP1 actin filament associated protein 1 -0.0253757
ANO6 anoctamin 6 -0.0251618
UBAC2 UBA domain containing 2 -0.0249469
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0248281
RPS14 ribosomal protein S14 -0.0247876
RPLP1 ribosomal protein, large, P1 -0.0246513
RRBP1 ribosome binding protein 1 -0.0245687
ZNF395 zinc finger protein 395 -0.0243105
VGLL4 vestigial-like family member 4 -0.0242819
MARCHF6 membrane associated ring-CH-type finger 6 -0.0240954
RAB7A RAB7A, member RAS oncogene family -0.0239525
NSD1 nuclear receptor binding SET domain protein 1 -0.0237092
GNAS GNAS complex locus -0.0236252
NACA nascent polypeptide-associated complex alpha subunit -0.0233877
MIER1 mesoderm induction early response 1, transcriptional regulator -0.0233506
ELL2 elongation factor, RNA polymerase II, 2 -0.0232327
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0232326
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 -0.0232222
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0230316
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0230259
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.0229054
GSK3B glycogen synthase kinase 3 beta -0.0228477
EIF3D eukaryotic translation initiation factor 3, subunit D -0.0228036
C2CD2 C2 calcium-dependent domain containing 2 -0.0227819
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0225073
F3 coagulation factor III (thromboplastin, tissue factor) -0.0224601
FRS2 fibroblast growth factor receptor substrate 2 -0.0224398
CD109 CD109 molecule -0.0222593
LMAN2 lectin, mannose-binding 2 -0.022232