Gallic acid (hydrate)_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.0693262
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0578328
ERBIN erbb2 interacting protein 0.0566681
DERA deoxyribose-phosphate aldolase (putative) 0.0545563
RPL23 ribosomal protein L23 0.0473169
NAP1L1 nucleosome assembly protein 1-like 1 0.041881
CEP250 centrosomal protein 250kDa 0.0414792
TRIO trio Rho guanine nucleotide exchange factor 0.041309
HOOK2 hook microtubule-tethering protein 2 0.0410479
RBM39 RNA binding motif protein 39 0.0407531
SMAD3 SMAD family member 3 0.0405253
XPO1 exportin 1 0.040249
CAPRIN2 caprin family member 2 0.0401452
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0392249
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0380961
SPAG9 sperm associated antigen 9 0.037971
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0379203
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0374691
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.03733
SAMD4A sterile alpha motif domain containing 4A 0.0369479
YAP1 Yes-associated protein 1 0.036766
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0365726
GOLGA4 golgin A4 0.0355211
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0350607
NAMPT nicotinamide phosphoribosyltransferase 0.0346549
NIPBL Nipped-B homolog (Drosophila) 0.0337685
ESYT2 extended synaptotagmin-like protein 2 0.0329095
PPP4R4 protein phosphatase 4, regulatory subunit 4 0.0309375
ATP13A3 ATPase type 13A3 0.030337
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.029888
CALU calumenin 0.0298189
ARRDC3 arrestin domain containing 3 0.0296128
NKTR natural killer cell triggering receptor 0.0294392
CKAP5 cytoskeleton associated protein 5 0.0293376
RASAL2 RAS protein activator like 2 0.0292323
MYOF myoferlin 0.0288337
MED13 mediator complex subunit 13 0.0288126
PBX3 pre-B-cell leukemia homeobox 3 0.0284956
SS18 synovial sarcoma translocation, chromosome 18 0.0284178
RAI1 retinoic acid induced 1 0.0276723
NIBAN2 niban apoptosis regulator 2 0.0272559
TXNRD1 thioredoxin reductase 1 0.0272204
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0271995
ANKRD37 ankyrin repeat domain 37 0.0266399
APLP2 amyloid beta (A4) precursor-like protein 2 0.0262925
BHLHE40 basic helix-loop-helix family, member e40 0.0258985
BASP1 brain abundant, membrane attached signal protein 1 0.0254358
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0253941
LMAN1 lectin, mannose-binding, 1 0.0252947
GSK3B glycogen synthase kinase 3 beta 0.0252811
WAC WW domain containing adaptor with coiled-coil 0.0252347
MED17 mediator complex subunit 17 0.0251016
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.0250673
CD59 CD59 molecule, complement regulatory protein 0.0249534
GIGYF2 GRB10 interacting GYF protein 2 0.0247036
TRA2A transformer 2 alpha homolog (Drosophila) 0.024505
BIRC3 baculoviral IAP repeat containing 3 0.024447
SMYD3 SET and MYND domain containing 3 0.0239224
PRRC2C proline-rich coiled-coil 2C 0.0237699
AFF4 AF4/FMR2 family, member 4 0.0235766
RAB5A RAB5A, member RAS oncogene family 0.0233396
IWS1 IWS1 homolog (S. cerevisiae) 0.0229508
PRPF4B pre-mRNA processing factor 4B 0.022845
SETD5 SET domain containing 5 0.0224121
USP3 ubiquitin specific peptidase 3 0.0224098
TUT4 terminal uridylyl transferase 4 0.0223058
MPRIP myosin phosphatase Rho interacting protein 0.0222539
TXNIP thioredoxin interacting protein 0.0221595
AHCTF1 AT hook containing transcription factor 1 0.022101
OGA O-GlcNAcase 0.0220675
KDM5A lysine (K)-specific demethylase 5A 0.0220455
EMSY EMSY transcriptional repressor, BRCA2 interacting 0.0218943
NBAS neuroblastoma amplified sequence 0.0218087
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0214773
ADAM17 ADAM metallopeptidase domain 17 0.0213674
AHNAK AHNAK nucleoprotein 0.0212932
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0212628
RPLP1 ribosomal protein, large, P1 0.0212617
PGK1 phosphoglycerate kinase 1 0.0211328
TNRC6B trinucleotide repeat containing 6B 0.0210093
TM9SF3 transmembrane 9 superfamily member 3 0.0208248
RRBP1 ribosome binding protein 1 0.0205867
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0204792
MT1X metallothionein 1X 0.0201783
OXSR1 oxidative stress responsive 1 0.0201071
GOLT1B golgi transport 1B 0.020105
KDM5B lysine (K)-specific demethylase 5B 0.0198841
TMEM168 transmembrane protein 168 0.0198676
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.0196074
WBP11 WW domain binding protein 11 0.0195367
SEPTIN2 septin 2 0.0195044
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0193338
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.019248
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0192038
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0190477
NGLY1 N-glycanase 1 0.0190261
FGD6 FYVE, RhoGEF and PH domain containing 6 0.0188899
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0188567
NPAT nuclear protein, ataxia-telangiectasia locus 0.0188225
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0186466

decreased expression

Symbol Name Standardized Value
LDHA lactate dehydrogenase A -0.0768938
HMGA2 high mobility group AT-hook 2 -0.0647214
SLC38A2 solute carrier family 38, member 2 -0.0539377
RIGI RNA sensor RIG-I -0.0505255
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0480821
MBNL1 muscleblind-like splicing regulator 1 -0.0467747
ZBTB20 zinc finger and BTB domain containing 20 -0.0432853
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0431864
PRR16 proline rich 16 -0.0423216
INTS6 integrator complex subunit 6 -0.0419047
DNER delta/notch-like EGF repeat containing -0.0411771
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.0404705
CD44 CD44 molecule (Indian blood group) -0.0396208
VCL vinculin -0.0394712
GPC5 glypican 5 -0.0388786
IGF2 insulin-like growth factor 2 -0.0372508
FBXL7 F-box and leucine-rich repeat protein 7 -0.0368707
POTEF POTE ankyrin domain family, member F -0.0359298
FTH1 ferritin, heavy polypeptide 1 -0.0351923
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0347519
TPM4 tropomyosin 4 -0.0342618
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0334253
ATM ATM serine/threonine kinase -0.0332993
AEBP2 AE binding protein 2 -0.0326105
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0322092
EGR1 early growth response 1 -0.03204
PCNX4 pecanex 4 -0.0319271
SVIL supervillin -0.0306625
TM4SF1 transmembrane 4 L six family member 1 -0.0306505
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0306421
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0291715
ACTG1 actin gamma 1 -0.0287394
GPC6 glypican 6 -0.0287344
BABAM2 BRISC and BRCA1 A complex member 2 -0.0283253
ATXN1 ataxin 1 -0.0281579
EFNA5 ephrin-A5 -0.0273555
FAM3C family with sequence similarity 3, member C -0.0264039
AGO2 argonaute RISC catalytic component 2 -0.026396
TAPBP TAP binding protein (tapasin) -0.0258133
GLS2 glutaminase 2 (liver, mitochondrial) -0.0258096
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0256341
ATG7 autophagy related 7 -0.0249434
SATB2 SATB homeobox 2 -0.0249009
LRRC49 leucine rich repeat containing 49 -0.0247086
NT5E 5'-nucleotidase, ecto (CD73) -0.0241284
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0241229
STAU2 staufen double-stranded RNA binding protein 2 -0.0239716
FMN1 formin 1 -0.0237856
SCLT1 sodium channel and clathrin linker 1 -0.0229269
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0229174
PRSS23 protease, serine, 23 -0.0228502
MACF1 microtubule-actin crosslinking factor 1 -0.0224522
ITPRID2 ITPR interacting domain containing 2 -0.0223816
ZNF609 zinc finger protein 609 -0.0218716
NPAS2 neuronal PAS domain protein 2 -0.0218351
EXOC4 exocyst complex component 4 -0.0217156
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0212165
SPDL1 spindle apparatus coiled-coil protein 1 -0.021127
DEK DEK proto-oncogene -0.0209644
PRELID2 PRELI domain containing 2 -0.0208743
DST dystonin -0.0208278
TBC1D5 TBC1 domain family, member 5 -0.0207898
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -0.0206943
VDAC1 voltage-dependent anion channel 1 -0.0204439
PTPRG protein tyrosine phosphatase, receptor type, G -0.0203405
RANBP17 RAN binding protein 17 -0.0203353
MAP4 microtubule-associated protein 4 -0.0202375
SLC35E3 solute carrier family 35, member E3 -0.0202231
NAV2 neuron navigator 2 -0.0200481
EHBP1 EH domain binding protein 1 -0.0198299
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.0197718
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0197231
DOCK4 dedicator of cytokinesis 4 -0.0196606
PTS 6-pyruvoyltetrahydropterin synthase -0.019519
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0194856
DENND5B DENN/MADD domain containing 5B -0.019438
NABP1 nucleic acid binding protein 1 -0.019434
TLE4 transducin-like enhancer of split 4 -0.0191658
LRP6 low density lipoprotein receptor-related protein 6 -0.0190902
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0190321
WWOX WW domain containing oxidoreductase -0.0190233
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -0.0188384
ENO1 enolase 1, (alpha) -0.0187602
MBNL2 muscleblind-like splicing regulator 2 -0.0186336
MBD5 methyl-CpG binding domain protein 5 -0.0185887
CENPF centromere protein F, 350/400kDa -0.0185599
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0185144
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.018341
SOGA1 suppressor of glucose, autophagy associated 1 -0.0183292
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -0.0182461
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0182141
HLA-C major histocompatibility complex, class I, C -0.0182058
AVIL advillin -0.0181516
RABGAP1L RAB GTPase activating protein 1-like -0.0180926
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0180431
CCDC88A coiled-coil domain containing 88A -0.0180399
BIRC6 baculoviral IAP repeat containing 6 -0.0178601
ZFAND5 zinc finger, AN1-type domain 5 -0.0178546
N4BP2L2 NEDD4 binding protein 2-like 2 -0.017854
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.0177059