Gallic acid (hydrate)_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SW 900 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.108583
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.065381
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0631644
AKAP12 A kinase (PRKA) anchor protein 12 0.0573577
CANX calnexin 0.0546025
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0424081
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0415679
ZCCHC7 zinc finger, CCHC domain containing 7 0.0399834
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0383017
PLIN2 perilipin 2 0.0369067
CALR calreticulin 0.0362425
TPR translocated promoter region, nuclear basket protein 0.0356692
GOLGA4 golgin A4 0.0346867
UBC ubiquitin C 0.0343497
PTMA prothymosin, alpha 0.032274
TMF1 TATA element modulatory factor 1 0.0320914
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0314694
PDIA3 protein disulfide isomerase family A, member 3 0.0310395
ENO1 enolase 1, (alpha) 0.0303034
KTN1 kinectin 1 (kinesin receptor) 0.0284294
CEP350 centrosomal protein 350kDa 0.0275348
PGK1 phosphoglycerate kinase 1 0.0266459
CXCL8 chemokine (C-X-C motif) ligand 8 0.0260753
SCFD1 sec1 family domain containing 1 0.0259152
SRP54 signal recognition particle 54kDa 0.0253465
RPS27A ribosomal protein S27a 0.0253352
SKAP2 src kinase associated phosphoprotein 2 0.0253344
PDIA4 protein disulfide isomerase family A, member 4 0.0251662
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.02506
TTC3 tetratricopeptide repeat domain 3 0.0246708
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0244326
CD109 CD109 molecule 0.0227648
GOLGB1 golgin B1 0.022585
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0220113
TXNIP thioredoxin interacting protein 0.0219262
HMGB3 high mobility group box 3 0.0219242
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0218554
AKAP9 A kinase (PRKA) anchor protein 9 0.0216168
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0213037
SUCO SUN domain containing ossification factor 0.0210733
ARID4B AT rich interactive domain 4B (RBP1-like) 0.0202196
HDGF hepatoma-derived growth factor 0.0201674
EEF2 eukaryotic translation elongation factor 2 0.0198588
KMT2E lysine (K)-specific methyltransferase 2E 0.0193002
COPA coatomer protein complex, subunit alpha 0.0192295
RPS6 ribosomal protein S6 0.0189148
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0187178
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0184611
ITCH itchy E3 ubiquitin protein ligase 0.0183809
MT2A metallothionein 2A 0.0182033
PDE4D phosphodiesterase 4D, cAMP-specific 0.0179494
KDM2A lysine (K)-specific demethylase 2A 0.0178421
DOCK5 dedicator of cytokinesis 5 0.0177098
TPM3 tropomyosin 3 0.0169599
NSD3 nuclear receptor binding SET domain protein 3 0.0167154
CAND1 cullin-associated and neddylation-dissociated 1 0.0166416
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0166172
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0165123
SLC41A2 solute carrier family 41 (magnesium transporter), member 2 0.0163967
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0162537
FMN1 formin 1 0.0160993
MTDH metadherin 0.0159415
YTHDC1 YTH domain containing 1 0.0158894
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0158881
MRPS6 mitochondrial ribosomal protein S6 0.0158454
KDM3A lysine (K)-specific demethylase 3A 0.0158424
RNF145 ring finger protein 145 0.0157698
ARHGAP42 Rho GTPase activating protein 42 0.0157508
DENND4C DENN/MADD domain containing 4C 0.0157313
FAM13A family with sequence similarity 13, member A 0.0157144
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 0.0156433
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 0.0155753
SOS1 son of sevenless homolog 1 (Drosophila) 0.0153849
R3HDM1 R3H domain containing 1 0.0152281
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.0151958
RIC1 RAB6A GEF complex partner 1 0.0151829
RPS3 ribosomal protein S3 0.0149762
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0147777
SRRM1 serine/arginine repetitive matrix 1 0.0146992
EPN2 epsin 2 0.014684
ACBD3 acyl-CoA binding domain containing 3 0.014679
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0146301
SCAF11 SR-related CTD-associated factor 11 0.0145803
SAFB scaffold attachment factor B 0.0145226
KIF16B kinesin family member 16B 0.0145048
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.0144138
ERRFI1 ERBB receptor feedback inhibitor 1 0.0142006
SERINC1 serine incorporator 1 0.0140227
PDIA6 protein disulfide isomerase family A, member 6 0.0140209
SOD2 superoxide dismutase 2, mitochondrial 0.0138905
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.0137449
NKTR natural killer cell triggering receptor 0.013626
CENPF centromere protein F, 350/400kDa 0.0134441
STC1 stanniocalcin 1 0.0133388
ZNF146 zinc finger protein 146 0.0133348
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.0133286
PRPF6 pre-mRNA processing factor 6 0.0132879
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0132562
GMCL1 germ cell-less, spermatogenesis associated 1 0.0131571
JMY junction mediating and regulatory protein, p53 cofactor 0.0131229

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.203023
FN1 fibronectin 1 -0.177181
NRG1 neuregulin 1 -0.139713
HMGA2 high mobility group AT-hook 2 -0.0815703
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0781573
FNDC3B fibronectin type III domain containing 3B -0.0775729
GRB10 growth factor receptor-bound protein 10 -0.0713016
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0692974
NAMPT nicotinamide phosphoribosyltransferase -0.0677295
IFI27 interferon, alpha-inducible protein 27 -0.0632004
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.061962
SQSTM1 sequestosome 1 -0.0616837
GLIS3 GLIS family zinc finger 3 -0.0602237
EXT1 exostosin glycosyltransferase 1 -0.0588299
NDRG1 N-myc downstream regulated 1 -0.0556602
TRIO trio Rho guanine nucleotide exchange factor -0.0552312
HLA-B major histocompatibility complex, class I, B -0.0527409
VCL vinculin -0.0525783
TMEM156 transmembrane protein 156 -0.0521961
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0470506
LRMDA leucine rich melanocyte differentiation associated -0.0468512
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0464572
TPT1 tumor protein, translationally-controlled 1 -0.0457767
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0442903
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0432708
MAP1B microtubule-associated protein 1B -0.0419862
PTK2 protein tyrosine kinase 2 -0.0399125
AHNAK AHNAK nucleoprotein -0.0352698
RPS24 ribosomal protein S24 -0.0347667
TENM4 teneurin transmembrane protein 4 -0.0346981
RPS21 ribosomal protein S21 -0.034636
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0343968
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.0339057
TMSB10 thymosin beta 10 -0.0339026
DNAH5 dynein, axonemal, heavy chain 5 -0.0320661
EFNA5 ephrin-A5 -0.031836
RAB7A RAB7A, member RAS oncogene family -0.0316864
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0301119
SYT1 synaptotagmin I -0.0299086
NRP1 neuropilin 1 -0.029524
NCOA7 nuclear receptor coactivator 7 -0.0295036
ANKRD11 ankyrin repeat domain 11 -0.0292933
KLHL5 kelch-like family member 5 -0.0290385
LIMCH1 LIM and calponin homology domains 1 -0.0283084
TGFA transforming growth factor, alpha -0.0281439
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0279498
SOX4 SRY (sex determining region Y)-box 4 -0.0277403
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0271332
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 -0.027127
ETV1 ets variant 1 -0.0271243
ACTN4 actinin, alpha 4 -0.0270216
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0269786
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0269472
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0268223
ASPH aspartate beta-hydroxylase -0.0266187
IFI6 interferon, alpha-inducible protein 6 -0.0266117
RPL35A ribosomal protein L35a -0.0265968
SMAD3 SMAD family member 3 -0.0264445
WDR1 WD repeat domain 1 -0.0262572
ITGA1 integrin, alpha 1 -0.0258619
AFF4 AF4/FMR2 family, member 4 -0.025701
GNAS GNAS complex locus -0.025457
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0254072
H1-0 H1.0 linker histone -0.025326
OASL 2'-5'-oligoadenylate synthetase-like -0.0251801
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0249718
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0248125
FTH1 ferritin, heavy polypeptide 1 -0.0242352
UBAP1 ubiquitin associated protein 1 -0.0242225
RUNX1 runt-related transcription factor 1 -0.0241913
CCND1 cyclin D1 -0.0239471
NTN4 netrin 4 -0.0238122
ATXN1 ataxin 1 -0.023485
SFRP1 secreted frizzled-related protein 1 -0.0234755
IGFBP5 insulin-like growth factor binding protein 5 -0.0234548
SFTPA2 surfactant protein A2 -0.023284
SOX5 SRY (sex determining region Y)-box 5 -0.0226154
RPL9 ribosomal protein L9 -0.0223352
RPL12 ribosomal protein L12 -0.0218886
LOC112694756 uncharaterized LOC112694756 -0.021758
TM4SF1 transmembrane 4 L six family member 1 -0.0217489
EGR1 early growth response 1 -0.0217111
RBM39 RNA binding motif protein 39 -0.0216359
RPL26 ribosomal protein L26 -0.0214016
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0213123
MCTP2 multiple C2 domains, transmembrane 2 -0.0210684
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0209872
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0208095
CTSD cathepsin D -0.0207154
NPC1 Niemann-Pick disease, type C1 -0.020501
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0204783
HMGA1 high mobility group AT-hook 1 -0.0203696
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.0201941
RPL38 ribosomal protein L38 -0.0201866
TTC28 tetratricopeptide repeat domain 28 -0.020034
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0199985
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0198743
LY6E lymphocyte antigen 6 complex, locus E -0.0198428
BICD1 bicaudal D homolog 1 (Drosophila) -0.0198135
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.019746