Gallic acid (hydrate)_SW1417 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SW1417 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0932125
PTMA prothymosin, alpha 0.0648812
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0571491
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0547596
CENPF centromere protein F, 350/400kDa 0.0537943
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0488896
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0462052
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0441343
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.043865
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0420666
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0416687
TPX2 TPX2, microtubule-associated 0.0392751
RPL23 ribosomal protein L23 0.0388391
RPL21 ribosomal protein L21 0.0370807
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0369807
DSPP dentin sialophosphoprotein 0.0369496
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0361136
RPS12 ribosomal protein S12 0.0358351
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0356554
PDIA3 protein disulfide isomerase family A, member 3 0.0354104
FXR1 fragile X mental retardation, autosomal homolog 1 0.0351669
CANX calnexin 0.0350571
KTN1 kinectin 1 (kinesin receptor) 0.0348634
SDK1 sidekick cell adhesion molecule 1 0.034574
FTL ferritin, light polypeptide 0.0337838
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0336812
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0316181
XPO1 exportin 1 0.0310503
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0287404
SMC4 structural maintenance of chromosomes 4 0.0282256
MED13L mediator complex subunit 13-like 0.0278774
DPY19L1 dpy-19-like 1 (C. elegans) 0.0276207
CD46 CD46 molecule, complement regulatory protein 0.0271943
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0262169
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.025782
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0257178
TOP2B topoisomerase (DNA) II beta 180kDa 0.0255005
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0253774
EIF2A eukaryotic translation initiation factor 2A, 65kDa 0.0251987
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.0250602
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0248519
USP3 ubiquitin specific peptidase 3 0.024834
PDIA6 protein disulfide isomerase family A, member 6 0.0247483
NIPBL Nipped-B homolog (Drosophila) 0.0246978
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0244756
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0244527
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0242051
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.02414
SERINC5 serine incorporator 5 0.0237629
MKI67 marker of proliferation Ki-67 0.0232687
RPL18 ribosomal protein L18 0.0230937
GOLGA4 golgin A4 0.0227481
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0221177
TXNIP thioredoxin interacting protein 0.0220012
ZNF292 zinc finger protein 292 0.0217002
TES testin LIM domain protein 0.0213696
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0211328
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0210181
XRN2 5'-3' exoribonuclease 2 0.0209847
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0209696
VMP1 vacuole membrane protein 1 0.0208457
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0208365
DSTN destrin (actin depolymerizing factor) 0.020673
RAD51B RAD51 paralog B 0.0205743
ADAM10 ADAM metallopeptidase domain 10 0.0205046
CKAP5 cytoskeleton associated protein 5 0.0204962
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0204857
SLTM SAFB-like, transcription modulator 0.0204318
CBX3 chromobox homolog 3 0.0203677
KDM6A lysine (K)-specific demethylase 6A 0.0202283
DDIT4 DNA-damage-inducible transcript 4 0.0201155
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0200575
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.019896
RASA2 RAS p21 protein activator 2 0.01985
FMR1 fragile X mental retardation 1 0.0196973
NAP1L1 nucleosome assembly protein 1-like 1 0.0196944
U2SURP U2 snRNP-associated SURP domain containing 0.0196648
RPS3 ribosomal protein S3 0.0194976
RAD21 RAD21 homolog (S. pombe) 0.0194865
YAP1 Yes-associated protein 1 0.0194684
TM9SF3 transmembrane 9 superfamily member 3 0.0193891
CSDE1 cold shock domain containing E1, RNA-binding 0.0193356
COPB1 coatomer protein complex, subunit beta 1 0.0192899
CLINT1 clathrin interactor 1 0.0192832
FNBP4 formin binding protein 4 0.0192759
NHSL1 NHS-like 1 0.0192376
ECT2 epithelial cell transforming 2 0.0188463
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0186657
RPL26 ribosomal protein L26 0.0186582
RYK receptor-like tyrosine kinase 0.0186212
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.018545
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0184633
CSNK1A1 casein kinase 1, alpha 1 0.0184583
STRN3 striatin, calmodulin binding protein 3 0.0181968
ENO1 enolase 1, (alpha) 0.0181778
RPL10A ribosomal protein L10a 0.0180374
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0178696
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0178435
TRIO trio Rho guanine nucleotide exchange factor 0.0178205
HMGB2 high mobility group box 2 0.0178158

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.1423
TMSB10 thymosin beta 10 -0.0749525
FTH1 ferritin, heavy polypeptide 1 -0.0734213
CCND1 cyclin D1 -0.0613965
LOC102724023 ES1 protein homolog, mitochondrial -0.0605639
KRT8 keratin 8, type II -0.0604245
EIF1 eukaryotic translation initiation factor 1 -0.0592786
ACTG1 actin gamma 1 -0.0587375
MAML2 mastermind-like 2 (Drosophila) -0.054631
CST3 cystatin C -0.054095
RPLP1 ribosomal protein, large, P1 -0.0529314
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0495005
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0468404
ACTN4 actinin, alpha 4 -0.0463067
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0443132
FLNA filamin A, alpha -0.0418449
ZNFX1 zinc finger, NFX1-type containing 1 -0.039351
FUS FUS RNA binding protein -0.0392741
LOC112694756 uncharaterized LOC112694756 -0.0387568
BCL2L1 BCL2-like 1 -0.0360812
HLA-A major histocompatibility complex, class I, A -0.0356814
RPL32 ribosomal protein L32 -0.0354105
EGR1 early growth response 1 -0.0353492
ZBTB20 zinc finger and BTB domain containing 20 -0.0351445
ZMYND8 zinc finger, MYND-type containing 8 -0.0338817
P4HB prolyl 4-hydroxylase, beta polypeptide -0.033037
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0328576
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0324427
RPS15 ribosomal protein S15 -0.0320132
PLEC plectin -0.0318511
GNAS GNAS complex locus -0.031728
RPL13A ribosomal protein L13a -0.0313971
BRD2 bromodomain containing 2 -0.0300161
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0299987
AHNAK AHNAK nucleoprotein -0.0290041
ITGB4 integrin, beta 4 -0.0289699
LMNA lamin A/C -0.0288631
MIDN midnolin -0.0285823
RPS11 ribosomal protein S11 -0.028356
PRRC2B proline-rich coiled-coil 2B -0.0283355
RPL28 ribosomal protein L28 -0.0278143
RPL38 ribosomal protein L38 -0.027735
SEC31A SEC31 homolog A (S. cerevisiae) -0.0272836
RPL35A ribosomal protein L35a -0.027075
PKM pyruvate kinase, muscle -0.0269923
MAP4 microtubule-associated protein 4 -0.026717
MT2A metallothionein 2A -0.0265386
HM13 histocompatibility (minor) 13 -0.0264254
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0263898
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0262367
S100A10 S100 calcium binding protein A10 -0.0258404
DLG1 discs, large homolog 1 (Drosophila) -0.025473
ATP5F1B ATP synthase F1 subunit beta -0.0254077
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0254071
RPS20 ribosomal protein S20 -0.0252369
NDRG1 N-myc downstream regulated 1 -0.0251243
NCOR2 nuclear receptor corepressor 2 -0.0249254
AGO2 argonaute RISC catalytic component 2 -0.0248264
WNK1 WNK lysine deficient protein kinase 1 -0.0241395
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 -0.0240099
CDK13 cyclin-dependent kinase 13 -0.023486
RPL8 ribosomal protein L8 -0.0234197
MYH14 myosin, heavy chain 14, non-muscle -0.0226149
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0225887
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.022564
RPS29 ribosomal protein S29 -0.0222333
MON2 MON2 homolog (S. cerevisiae) -0.021412
HDLBP high density lipoprotein binding protein -0.0213893
RPS23 ribosomal protein S23 -0.0212396
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.0205983
ADNP activity-dependent neuroprotector homeobox -0.020498
ATXN2 ataxin 2 -0.0203937
ZFHX3 zinc finger homeobox 3 -0.0202556
HLA-B major histocompatibility complex, class I, B -0.0201246
CEP95 centrosomal protein 95kDa -0.0200044
DIAPH1 diaphanous-related formin 1 -0.0198985
RPL7A ribosomal protein L7a -0.019891
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0197306
SRRM3 serine/arginine repetitive matrix 3 -0.0196035
HELZ2 helicase with zinc finger 2, transcriptional coactivator -0.0195959
S100A2 S100 calcium binding protein A2 -0.0195805
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0193082
ZFP36 ZFP36 ring finger protein -0.019122
IRF1 interferon regulatory factor 1 -0.0188828
RPS21 ribosomal protein S21 -0.0186496
JMJD1C jumonji domain containing 1C -0.0185586
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -0.018489
ZBTB38 zinc finger and BTB domain containing 38 -0.0184234
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0183856
CLDN4 claudin 4 -0.0183523
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0183181
RPL30 ribosomal protein L30 -0.0182024
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -0.0180851
IER3 immediate early response 3 -0.0180819
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -0.0176032
PPL periplakin -0.0175564
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.017424
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -0.0172602
PLEKHA7 pleckstrin homology domain containing, family A member 7 -0.0172057
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.017119