Gallic acid (hydrate)_SW48 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SW48 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.149597
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.115286
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.102018
HSPA8 heat shock 70kDa protein 8 0.0753057
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0748374
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0743108
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0617039
RPS12 ribosomal protein S12 0.0600262
TPT1 tumor protein, translationally-controlled 1 0.0579516
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0521584
BIRC3 baculoviral IAP repeat containing 3 0.0520779
RPS6 ribosomal protein S6 0.0509416
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0496628
LDHA lactate dehydrogenase A 0.0491137
IER3 immediate early response 3 0.0482577
FHIT fragile histidine triad 0.0471297
SET SET nuclear proto-oncogene 0.0470772
RPS3 ribosomal protein S3 0.0428797
ENO1 enolase 1, (alpha) 0.0386729
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0386269
RPL23 ribosomal protein L23 0.0379863
SQSTM1 sequestosome 1 0.035581
RPL37A ribosomal protein L37a 0.0337373
ANXA1 annexin A1 0.0336199
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.033451
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0321077
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0312249
EIF4B eukaryotic translation initiation factor 4B 0.0305834
RPS8 ribosomal protein S8 0.0304216
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0303566
RPL26 ribosomal protein L26 0.0286888
RPL3 ribosomal protein L3 0.0286688
ZFP36L1 ZFP36 ring finger protein-like 1 0.0286146
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0280318
HILPDA hypoxia inducible lipid droplet-associated 0.0276259
PRRC2C proline-rich coiled-coil 2C 0.0272638
KDM5C lysine (K)-specific demethylase 5C 0.0261921
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0259286
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0258229
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0253761
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0252264
RPL4 ribosomal protein L4 0.0248047
CANX calnexin 0.0246281
RPS7 ribosomal protein S7 0.0242979
MACF1 microtubule-actin crosslinking factor 1 0.0242235
EFNB2 ephrin-B2 0.023868
CHD4 chromodomain helicase DNA binding protein 4 0.0235464
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0234899
WWOX WW domain containing oxidoreductase 0.0234849
RPS27A ribosomal protein S27a 0.0234793
HDLBP high density lipoprotein binding protein 0.0233261
TGFB2 transforming growth factor, beta 2 0.0231692
EEF2 eukaryotic translation elongation factor 2 0.0227082
SAMD4A sterile alpha motif domain containing 4A 0.022638
AHNAK AHNAK nucleoprotein 0.0225818
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0224607
KTN1 kinectin 1 (kinesin receptor) 0.0224488
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.021919
RPL36 ribosomal protein L36 0.0218196
TOP2B topoisomerase (DNA) II beta 180kDa 0.0209378
PLAUR plasminogen activator, urokinase receptor 0.0209067
DIAPH2 diaphanous-related formin 2 0.0208225
SKI SKI proto-oncogene 0.0205778
RAD50 RAD50 homolog (S. cerevisiae) 0.0202175
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0201232
EPCAM epithelial cell adhesion molecule 0.0201185
SRRM2 serine/arginine repetitive matrix 2 0.0200461
AFDN afadin, adherens junction formation factor 0.0200408
LARS1 leucyl-tRNA synthetase 1 0.0199509
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.0199378
RPS17 ribosomal protein S17 0.019342
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.0191014
CEP290 centrosomal protein 290kDa 0.0189987
RPL35A ribosomal protein L35a 0.0189839
MYO5B myosin VB 0.0189202
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.0187778
CLIP2 CAP-GLY domain containing linker protein 2 0.0183304
SAFB2 scaffold attachment factor B2 0.0182927
RCC1 regulator of chromosome condensation 1 0.0181728
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0178772
RPL14 ribosomal protein L14 0.0175382
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.0174952
DUSP6 dual specificity phosphatase 6 0.0173712
SENP5 SUMO1/sentrin specific peptidase 5 0.0172916
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0172255
FOXK1 forkhead box K1 0.0171029
PRELID2 PRELI domain containing 2 0.017016
TCP1 t-complex 1 0.0168812
NCEH1 neutral cholesterol ester hydrolase 1 0.0167622
RPS2 ribosomal protein S2 0.0166943
EIF5B eukaryotic translation initiation factor 5B 0.0166051
ANXA2 annexin A2 0.0165697
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0164368
PNN pinin, desmosome associated protein 0.0162028
KRT18 keratin 18, type I 0.0161933
LOC112694756 uncharaterized LOC112694756 0.0161442
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.0160911
FUBP1 far upstream element (FUSE) binding protein 1 0.0160796
EMP1 epithelial membrane protein 1 0.0160201
CALR calreticulin 0.0158502

decreased expression

Symbol Name Standardized Value
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.194917
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.117305
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.102103
EGR1 early growth response 1 -0.0996416
FERMT1 fermitin family member 1 -0.0991363
HMGA2 high mobility group AT-hook 2 -0.0819314
CD36 CD36 molecule (thrombospondin receptor) -0.0803555
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0700303
LMO7 LIM domain 7 -0.0639648
EGFR epidermal growth factor receptor -0.0613501
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0597551
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0512252
RCOR1 REST corepressor 1 -0.0459774
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.044133
PTK2 protein tyrosine kinase 2 -0.040398
EZR ezrin -0.0401116
COG5 component of oligomeric golgi complex 5 -0.0389882
SETD5 SET domain containing 5 -0.0385794
MAP4 microtubule-associated protein 4 -0.0379201
FOSL1 FOS-like antigen 1 -0.0378502
TXNRD1 thioredoxin reductase 1 -0.0356662
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.035568
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0355374
ACTG1 actin gamma 1 -0.0354587
RNF43 ring finger protein 43 -0.0351832
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0349433
S100A10 S100 calcium binding protein A10 -0.0347868
VMP1 vacuole membrane protein 1 -0.0344594
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0343663
LAMC2 laminin, gamma 2 -0.0342784
MTUS1 microtubule associated tumor suppressor 1 -0.0338653
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0335619
MPRIP myosin phosphatase Rho interacting protein -0.0330817
OXR1 oxidation resistance 1 -0.0324751
RUNX2 runt-related transcription factor 2 -0.0319246
NTSR1 neurotensin receptor 1 (high affinity) -0.0314432
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 -0.0312814
ZFAND3 zinc finger, AN1-type domain 3 -0.0311463
AKAP13 A kinase (PRKA) anchor protein 13 -0.030887
DIAPH3 diaphanous-related formin 3 -0.0307224
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0303302
PDE4B phosphodiesterase 4B, cAMP-specific -0.0303
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.0302753
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0300255
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0295384
FBXO11 F-box protein 11 -0.0292138
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -0.0288054
PKP4 plakophilin 4 -0.0285711
ACTN4 actinin, alpha 4 -0.0284224
OSBPL3 oxysterol binding protein-like 3 -0.0279623
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0277055
RPS15 ribosomal protein S15 -0.0275318
GRB10 growth factor receptor-bound protein 10 -0.0274094
PDLIM5 PDZ and LIM domain 5 -0.0273576
SNX9 sorting nexin 9 -0.0267344
LPP LIM domain containing preferred translocation partner in lipoma -0.0266422
CDK13 cyclin-dependent kinase 13 -0.0265338
BRD2 bromodomain containing 2 -0.0262762
RBM25 RNA binding motif protein 25 -0.0260399
RFX7 regulatory factor X, 7 -0.0255782
PARD3 par-3 family cell polarity regulator -0.0255573
HMGA1 high mobility group AT-hook 1 -0.0255469
IARS1 isoleucyl-tRNA synthetase 1 -0.0254021
PTMA prothymosin, alpha -0.02532
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0252749
NBAS neuroblastoma amplified sequence -0.0252492
FHL2 four and a half LIM domains 2 -0.0252018
RPL32 ribosomal protein L32 -0.0249159
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0239966
NUP50 nucleoporin 50kDa -0.0237702
BIRC6 baculoviral IAP repeat containing 6 -0.023674
ANKRD28 ankyrin repeat domain 28 -0.0233392
WASF2 WAS protein family, member 2 -0.0233066
SH3D19 SH3 domain containing 19 -0.023265
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.0230785
ATXN7L1 ataxin 7-like 1 -0.0230616
ACBD6 acyl-CoA binding domain containing 6 -0.0228489
BRD4 bromodomain containing 4 -0.0228401
ENO2 enolase 2 (gamma, neuronal) -0.0227925
ATP5F1B ATP synthase F1 subunit beta -0.0226435
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0225295
MKI67 marker of proliferation Ki-67 -0.0223204
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0222844
CCND1 cyclin D1 -0.0222165
TPM4 tropomyosin 4 -0.0221814
RPS5 ribosomal protein S5 -0.0221047
MBNL1 muscleblind-like splicing regulator 1 -0.0220536
NT5E 5'-nucleotidase, ecto (CD73) -0.0219
FLOT1 flotillin 1 -0.0218313
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.02176
WAC WW domain containing adaptor with coiled-coil -0.0217375
RAP1B RAP1B, member of RAS oncogene family -0.0215751
WNK1 WNK lysine deficient protein kinase 1 -0.0214272
DOCK5 dedicator of cytokinesis 5 -0.0214254
EIF1 eukaryotic translation initiation factor 1 -0.0213771
RPS23 ribosomal protein S23 -0.021343
EHBP1 EH domain binding protein 1 -0.0209355
SPATA13 spermatogenesis associated 13 -0.020798
NEK7 NIMA-related kinase 7 -0.0204516
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0204158