Gallic acid (hydrate)_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in SW480 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.135293
PTMA prothymosin, alpha 0.11587
NKD1 naked cuticle homolog 1 (Drosophila) 0.111812
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.110147
AKAP12 A kinase (PRKA) anchor protein 12 0.0632453
ENO1 enolase 1, (alpha) 0.061258
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0588882
RPS6 ribosomal protein S6 0.0551748
VIM vimentin 0.0525457
WWOX WW domain containing oxidoreductase 0.0510968
CDK6 cyclin-dependent kinase 6 0.0472616
RPS8 ribosomal protein S8 0.0466298
TPT1 tumor protein, translationally-controlled 1 0.0453529
RPL37A ribosomal protein L37a 0.0440098
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0434138
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0431804
RPS12 ribosomal protein S12 0.0430624
RPL23 ribosomal protein L23 0.0422746
RAD51B RAD51 paralog B 0.0421203
CCND1 cyclin D1 0.0409872
SET SET nuclear proto-oncogene 0.0374822
MT2A metallothionein 2A 0.0362982
RPL35A ribosomal protein L35a 0.0356156
SDK1 sidekick cell adhesion molecule 1 0.0345658
RPL26 ribosomal protein L26 0.034375
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0335748
SKAP1 src kinase associated phosphoprotein 1 0.0335162
CENPF centromere protein F, 350/400kDa 0.032791
ASPH aspartate beta-hydroxylase 0.0320037
PA2G4 proliferation-associated 2G4, 38kDa 0.0316919
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.031164
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0308119
ADGRL2 adhesion G protein-coupled receptor L2 0.0298347
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0293831
SERBP1 SERPINE1 mRNA binding protein 1 0.029376
EXOC4 exocyst complex component 4 0.0291895
RPS17 ribosomal protein S17 0.0287728
PDE4D phosphodiesterase 4D, cAMP-specific 0.0280633
RBP1 retinol binding protein 1, cellular 0.0274577
RPLP2 ribosomal protein, large, P2 0.0271444
SYT1 synaptotagmin I 0.0268533
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.0267776
TUBA1B tubulin, alpha 1b 0.0265996
RPS25 ribosomal protein S25 0.0260415
NAV2 neuron navigator 2 0.02592
TMSB10 thymosin beta 10 0.0248225
SPATA13 spermatogenesis associated 13 0.0247435
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0246843
LDHA lactate dehydrogenase A 0.0246808
RPS13 ribosomal protein S13 0.0240857
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.0239857
RABGAP1L RAB GTPase activating protein 1-like 0.0239552
RPS27A ribosomal protein S27a 0.0238775
KRT18 keratin 18, type I 0.0237757
NOP56 NOP56 ribonucleoprotein 0.0235656
RPL9 ribosomal protein L9 0.0235294
CDH13 cadherin 13 0.0230822
CBX3 chromobox homolog 3 0.0230131
IPO7 importin 7 0.0226685
RPS3 ribosomal protein S3 0.0225801
RPS19 ribosomal protein S19 0.0222177
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0221842
EIF3A eukaryotic translation initiation factor 3, subunit A 0.022168
ZBTB20 zinc finger and BTB domain containing 20 0.0221006
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0220736
NPAS2 neuronal PAS domain protein 2 0.0220225
MRPS6 mitochondrial ribosomal protein S6 0.0219162
TPM4 tropomyosin 4 0.0218995
DSPP dentin sialophosphoprotein 0.0218986
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0217525
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0215614
RPL31 ribosomal protein L31 0.0214343
CD44 CD44 molecule (Indian blood group) 0.0212547
RPL36A ribosomal protein L36a 0.0211722
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0208363
EIF5B eukaryotic translation initiation factor 5B 0.0205733
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0205596
RPL37 ribosomal protein L37 0.0203965
RAN RAN, member RAS oncogene family 0.0203308
TUBB4B tubulin, beta 4B class IVb 0.0200435
TMSB4X thymosin beta 4, X-linked 0.0199335
DIAPH2 diaphanous-related formin 2 0.0199148
RPL10A ribosomal protein L10a 0.0197707
ANO1 anoctamin 1, calcium activated chloride channel 0.0197111
MKI67 marker of proliferation Ki-67 0.0194713
FHIT fragile histidine triad 0.0193642
BACE2 beta-site APP-cleaving enzyme 2 0.0192777
EGFR epidermal growth factor receptor 0.0191209
SMC1A structural maintenance of chromosomes 1A 0.0187696
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.0186694
LOC102724023 ES1 protein homolog, mitochondrial 0.0186239
WDR43 WD repeat domain 43 0.0184846
NTSR1 neurotensin receptor 1 (high affinity) 0.0181924
BCL2L1 BCL2-like 1 0.0180061
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.0179291
FRMD5 FERM domain containing 5 0.0178694
HMGB1 high mobility group box 1 0.0177394
SAMD4A sterile alpha motif domain containing 4A 0.0177183
LRMDA leucine rich melanocyte differentiation associated 0.0174763
TNS3 tensin 3 0.0174686

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.121025
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0521376
ESYT2 extended synaptotagmin-like protein 2 -0.0489402
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0445252
MORF4L2 mortality factor 4 like 2 -0.0406248
RBM39 RNA binding motif protein 39 -0.0363408
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0335619
GOLGA4 golgin A4 -0.0335017
ARF4 ADP-ribosylation factor 4 -0.033388
EEF2 eukaryotic translation elongation factor 2 -0.0332203
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0324026
GARS1 glycyl-tRNA synthetase 1 -0.0306565
EZR ezrin -0.0303926
PCBP2 poly(rC) binding protein 2 -0.0301532
UBA6 ubiquitin-like modifier activating enzyme 6 -0.029459
OGA O-GlcNAcase -0.0291033
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0283309
BIRC6 baculoviral IAP repeat containing 6 -0.0277619
ETNK1 ethanolamine kinase 1 -0.0272984
KMT2E lysine (K)-specific methyltransferase 2E -0.0269709
KMT2C lysine (K)-specific methyltransferase 2C -0.0264159
SEC31A SEC31 homolog A (S. cerevisiae) -0.0259541
TRA2A transformer 2 alpha homolog (Drosophila) -0.0259234
IARS1 isoleucyl-tRNA synthetase 1 -0.025846
MARCHF6 membrane associated ring-CH-type finger 6 -0.0256673
NDRG1 N-myc downstream regulated 1 -0.0256231
DDIT4 DNA-damage-inducible transcript 4 -0.02459
EGR1 early growth response 1 -0.0244518
SETD5 SET domain containing 5 -0.0244192
PDE8A phosphodiesterase 8A -0.0243628
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0241507
CEMIP2 cell migration inducing hyaluronidase 2 -0.0237914
BRWD3 bromodomain and WD repeat domain containing 3 -0.0235452
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0234559
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.023047
HELZ helicase with zinc finger -0.0227469
GLG1 golgi glycoprotein 1 -0.0226896
COG5 component of oligomeric golgi complex 5 -0.0226729
NUP58 nucleoporin 58 -0.0225675
H1-0 H1.0 linker histone -0.0225561
RAB6A RAB6A, member RAS oncogene family -0.0223208
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.022025
COPA coatomer protein complex, subunit alpha -0.0218604
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0208902
JMJD1C jumonji domain containing 1C -0.0208735
RAB1A RAB1A, member RAS oncogene family -0.0205374
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0203331
WDR45B WD repeat domain 45B -0.0199722
MON2 MON2 homolog (S. cerevisiae) -0.0199251
KDM3A lysine (K)-specific demethylase 3A -0.0198537
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.0196668
MXD1 MAX dimerization protein 1 -0.0195736
WDFY2 WD repeat and FYVE domain containing 2 -0.0192989
BAZ2A bromodomain adjacent to zinc finger domain, 2A -0.0192718
WASF2 WAS protein family, member 2 -0.0192386
COPB1 coatomer protein complex, subunit beta 1 -0.0189403
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0186742
ADAM17 ADAM metallopeptidase domain 17 -0.0186394
CEP95 centrosomal protein 95kDa -0.0185013
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0184124
TMEM41B transmembrane protein 41B -0.0183228
ZNF292 zinc finger protein 292 -0.0181268
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0180768
NF1 neurofibromin 1 -0.0180088
SRP54 signal recognition particle 54kDa -0.0179858
ZMYM2 zinc finger, MYM-type 2 -0.0177172
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0176683
PAN3 PAN3 poly(A) specific ribonuclease subunit -0.0175867
NKTR natural killer cell triggering receptor -0.0175466
SUCO SUN domain containing ossification factor -0.0174894
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.0173164
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0172972
SBF2 SET binding factor 2 -0.017255
BHLHE40 basic helix-loop-helix family, member e40 -0.0171432
FHIP1A FHF complex subunit HOOK interacting protein 1A -0.0170111
ACBD3 acyl-CoA binding domain containing 3 -0.016646
ABHD2 abhydrolase domain containing 2 -0.0165962
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.0165946
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0163769
RIOK3 RIO kinase 3 -0.0162043
NPTN neuroplastin -0.016138
USP34 ubiquitin specific peptidase 34 -0.0160792
RLF rearranged L-myc fusion -0.0160533
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0160404
IFRD1 interferon-related developmental regulator 1 -0.0159988
EFNB2 ephrin-B2 -0.0159691
PDGFA platelet-derived growth factor alpha polypeptide -0.0159457
SPAG9 sperm associated antigen 9 -0.0158571
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0158142
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0156882
WDR26 WD repeat domain 26 -0.0153804
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0153549
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0152659
DIAPH3 diaphanous-related formin 3 -0.0152632
DLG1 discs, large homolog 1 (Drosophila) -0.0152168
AFDN afadin, adherens junction formation factor -0.0151034
DDIT3 DNA-damage-inducible transcript 3 -0.0150735
UBC ubiquitin C -0.0149875
HDLBP high density lipoprotein binding protein -0.0149484
LCORL ligand dependent nuclear receptor corepressor-like -0.0149274