Gallic acid (hydrate)_hTERT-HPNE Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid (hydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid (hydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
STC1 stanniocalcin 1 0.245301
INHBA inhibin, beta A 0.163374
VIM vimentin 0.137778
ASPH aspartate beta-hydroxylase 0.102515
TPT1 tumor protein, translationally-controlled 1 0.0896974
MT2A metallothionein 2A 0.0884382
TMSB10 thymosin beta 10 0.0833836
CXCL8 chemokine (C-X-C motif) ligand 8 0.0830722
RPL23 ribosomal protein L23 0.0804807
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0768556
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 0.0714792
DST dystonin 0.0682492
JARID2 jumonji, AT rich interactive domain 2 0.0672561
FNDC3B fibronectin type III domain containing 3B 0.0635626
HMGA2 high mobility group AT-hook 2 0.0626349
B2M beta-2-microglobulin 0.0618689
RPS12 ribosomal protein S12 0.061173
MYO10 myosin X 0.0589749
HLA-A major histocompatibility complex, class I, A 0.0589212
ZSWIM6 zinc finger, SWIM-type containing 6 0.0545813
FMNL2 formin-like 2 0.0539247
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.053684
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0504876
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0501118
AKAP12 A kinase (PRKA) anchor protein 12 0.0491063
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0467334
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0459874
ENO1 enolase 1, (alpha) 0.0459853
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0457179
RPS3 ribosomal protein S3 0.0451983
RPS8 ribosomal protein S8 0.0448386
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.0441855
ALCAM activated leukocyte cell adhesion molecule 0.0434544
TRIO trio Rho guanine nucleotide exchange factor 0.0429321
VCL vinculin 0.0427983
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.042628
FAM13A family with sequence similarity 13, member A 0.0425387
RUNX1 runt-related transcription factor 1 0.0420987
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.041539
PRELID2 PRELI domain containing 2 0.0404637
LOX lysyl oxidase 0.0402975
ZBTB20 zinc finger and BTB domain containing 20 0.0398098
PRKG1 protein kinase, cGMP-dependent, type I 0.0398006
NALF1 NALCN channel auxiliary factor 1 0.0394696
ZBTB38 zinc finger and BTB domain containing 38 0.038692
CEMIP cell migration inducing protein, hyaluronan binding 0.0386233
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0374155
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0368909
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0366646
HDAC9 histone deacetylase 9 0.0363623
ELL2 elongation factor, RNA polymerase II, 2 0.0356437
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0355209
EXOC4 exocyst complex component 4 0.035118
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0349983
COL8A1 collagen, type VIII, alpha 1 0.0342822
LDHA lactate dehydrogenase A 0.0338468
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0332318
TGFBI transforming growth factor, beta-induced, 68kDa 0.0328451
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0322326
COL4A1 collagen, type IV, alpha 1 0.0321885
GLIS3 GLIS family zinc finger 3 0.0318788
SFPQ splicing factor proline/glutamine-rich 0.0315108
RPLP0 ribosomal protein, large, P0 0.0312756
EHBP1 EH domain binding protein 1 0.0309268
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0307393
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0299928
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0295446
MBD5 methyl-CpG binding domain protein 5 0.0293241
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0290861
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.028813
IGFBP7 insulin-like growth factor binding protein 7 0.0285868
CALU calumenin 0.0284424
RPL9 ribosomal protein L9 0.0282412
RPS17 ribosomal protein S17 0.0281751
ANKRD12 ankyrin repeat domain 12 0.028025
RPL26 ribosomal protein L26 0.0279487
RPL11 ribosomal protein L11 0.0278738
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.0277223
CANX calnexin 0.0276779
PCBP3 poly(rC) binding protein 3 0.0276101
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0276035
RPL34 ribosomal protein L34 0.0275409
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0271514
RPL21 ribosomal protein L21 0.0271461
RPL18 ribosomal protein L18 0.0271306
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0270241
PDE4D phosphodiesterase 4D, cAMP-specific 0.0268097
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0266253
S100A9 S100 calcium binding protein A9 0.0265084
MMP12 matrix metallopeptidase 12 0.0261421
CLIC4 chloride intracellular channel 4 0.0259138
ATP13A3 ATPase type 13A3 0.0258124
CDK6 cyclin-dependent kinase 6 0.0256922
ZFP36L1 ZFP36 ring finger protein-like 1 0.0256047
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0253879
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.0251696
FNIP1 folliculin interacting protein 1 0.0250485
TMOD3 tropomodulin 3 (ubiquitous) 0.0249312
ATXN1 ataxin 1 0.0247304
SON SON DNA binding protein 0.0247152

decreased expression

Symbol Name Standardized Value
FN1 fibronectin 1 -0.142955
COL1A1 collagen, type I, alpha 1 -0.130702
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.099812
ACTG1 actin gamma 1 -0.0775741
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0413829
LOXL2 lysyl oxidase-like 2 -0.0360114
KIAA1549L KIAA1549-like -0.0346069
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0331595
ADGRB3 adhesion G protein-coupled receptor B3 -0.0327334
FTH1 ferritin, heavy polypeptide 1 -0.0325818
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0314576
TPM4 tropomyosin 4 -0.0275652
ARHGAP21 Rho GTPase activating protein 21 -0.0275554
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0271906
CCND1 cyclin D1 -0.0256884
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0246297
IGF2 insulin-like growth factor 2 -0.0236013
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0233589
COL1A2 collagen, type I, alpha 2 -0.0231935
PKM pyruvate kinase, muscle -0.0217968
EEF2 eukaryotic translation elongation factor 2 -0.0203397
FLNA filamin A, alpha -0.0201757
ATP5F1B ATP synthase F1 subunit beta -0.0200656
PDGFRB platelet-derived growth factor receptor, beta polypeptide -0.0199001
RPS16 ribosomal protein S16 -0.0197738
RAB6A RAB6A, member RAS oncogene family -0.0197366
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 -0.0196555
GPHN gephyrin -0.0186277
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.018535
DUSP10 dual specificity phosphatase 10 -0.0183796
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0181197
SEPTIN9 septin 9 -0.0176972
BRD2 bromodomain containing 2 -0.017556
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0173225
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0172869
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0171576
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0168545
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -0.0168311
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0166536
HSPB6 heat shock protein, alpha-crystallin-related, B6 -0.0166187
HAS2 hyaluronan synthase 2 -0.0162703
PPIB peptidylprolyl isomerase B (cyclophilin B) -0.0154864
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0153423
MEF2D myocyte enhancer factor 2D -0.015109
RHOA ras homolog family member A -0.0149799
AAK1 AP2 associated kinase 1 -0.0148405
IARS1 isoleucyl-tRNA synthetase 1 -0.0145522
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0145373
RBMX RNA binding motif protein, X-linked -0.0145216
G0S2 G0/G1 switch 2 -0.0143441
ECE1 endothelin converting enzyme 1 -0.0140421
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.013783
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0137327
MYH9 myosin, heavy chain 9, non-muscle -0.0135296
MEIS1 Meis homeobox 1 -0.0132922
CD44 CD44 molecule (Indian blood group) -0.0132643
COL6A2 collagen, type VI, alpha 2 -0.0131718
RTN4 reticulon 4 -0.0131074
PRRX1 paired related homeobox 1 -0.013023
UBC ubiquitin C -0.0129415
EMP1 epithelial membrane protein 1 -0.0129401
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0129386
GLI2 GLI family zinc finger 2 -0.0129023
VEGFA vascular endothelial growth factor A -0.0128169
IL33 interleukin 33 -0.0125875
PRPF8 pre-mRNA processing factor 8 -0.0125007
MON2 MON2 homolog (S. cerevisiae) -0.0124357
ATXN2 ataxin 2 -0.0122852
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0122479
SMAP2 small ArfGAP2 -0.0121899
COL5A3 collagen, type V, alpha 3 -0.0120605
NID2 nidogen 2 (osteonidogen) -0.0120515
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0120356
HSPG2 heparan sulfate proteoglycan 2 -0.0120325
BRAF B-Raf proto-oncogene, serine/threonine kinase -0.0119303
PGM3 phosphoglucomutase 3 -0.0118782
FRMPD4 FERM and PDZ domain containing 4 -0.0118531
MARCHF7 membrane associated ring-CH-type finger 7 -0.0117987
ZMYND8 zinc finger, MYND-type containing 8 -0.0117872
MAX MYC associated factor X -0.0117343
CCNK cyclin K -0.0117001
PER1 period circadian clock 1 -0.0116866
FTL ferritin, light polypeptide -0.0116563
WARS1 tryptophanyl-tRNA synthetase 1 -0.0116508
EGFR epidermal growth factor receptor -0.0116152
KMT2E lysine (K)-specific methyltransferase 2E -0.0115026
SOCS5 suppressor of cytokine signaling 5 -0.011368
RPS15 ribosomal protein S15 -0.0113471
KPNB1 karyopherin (importin) beta 1 -0.0112852
MAP2K1 mitogen-activated protein kinase kinase 1 -0.0112111
SEPTIN11 septin 11 -0.0111675
XPO6 exportin 6 -0.0111245
MARK4 MAP/microtubule affinity-regulating kinase 4 -0.0111151
GRN granulin -0.0110694
TUBB6 tubulin, beta 6 class V -0.0110125
UGCG UDP-glucose ceramide glucosyltransferase -0.0110033
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -0.0109981
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0109363
SCAF11 SR-related CTD-associated factor 11 -0.0109044
PPP1R18 protein phosphatase 1, regulatory subunit 18 -0.0108784