Gallic acid_AN3 CA Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in AN3 CA cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PRKG1 protein kinase, cGMP-dependent, type I 0.219638
PDE4D phosphodiesterase 4D, cAMP-specific 0.160869
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.130027
VEGFA vascular endothelial growth factor A 0.0817426
TSHZ2 teashirt zinc finger homeobox 2 0.0764058
CADM2 cell adhesion molecule 2 0.0701558
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.06256
PDE10A phosphodiesterase 10A 0.0617912
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.058859
FGFR1 fibroblast growth factor receptor 1 0.0565325
MEST mesoderm specific transcript 0.0523681
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.050738
PRELID2 PRELI domain containing 2 0.049895
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0492525
ACTG1 actin gamma 1 0.0429892
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.038919
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.0384016
PDE4B phosphodiesterase 4B, cAMP-specific 0.0377015
HMGA2 high mobility group AT-hook 2 0.0371243
ZBTB20 zinc finger and BTB domain containing 20 0.0342661
RPL3 ribosomal protein L3 0.0337138
MYOF myoferlin 0.0337056
THSD4 thrombospondin, type I, domain containing 4 0.0335141
PCM1 pericentriolar material 1 0.0324018
MTUS1 microtubule associated tumor suppressor 1 0.0311489
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.031094
TPK1 thiamin pyrophosphokinase 1 0.0296977
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0290774
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0278588
KANK1 KN motif and ankyrin repeat domains 1 0.0271304
TET1 tet methylcytosine dioxygenase 1 0.0271068
HSPA8 heat shock 70kDa protein 8 0.0267955
FNDC3B fibronectin type III domain containing 3B 0.0254486
DOCK1 dedicator of cytokinesis 1 0.024872
LINGO2 leucine rich repeat and Ig domain containing 2 0.0240449
SOX4 SRY (sex determining region Y)-box 4 0.0239544
ATG10 autophagy related 10 0.0239382
ANO6 anoctamin 6 0.0239169
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0236265
USP9X ubiquitin specific peptidase 9, X-linked 0.0231454
NBEA neurobeachin 0.0225769
CHD3 chromodomain helicase DNA binding protein 3 0.0222883
FNIP1 folliculin interacting protein 1 0.0220422
LPP LIM domain containing preferred translocation partner in lipoma 0.0219638
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0218936
PHF14 PHD finger protein 14 0.0217625
SPRY2 sprouty homolog 2 (Drosophila) 0.0212649
ZMIZ1 zinc finger, MIZ-type containing 1 0.0211587
OPHN1 oligophrenin 1 0.0209962
AOPEP aminopeptidase O (putative) 0.0209452
FAM13A family with sequence similarity 13, member A 0.0208624
RAD51B RAD51 paralog B 0.0203494
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0200087
EIF4H eukaryotic translation initiation factor 4H 0.0199752
EYA1 EYA transcriptional coactivator and phosphatase 1 0.0198685
PRKN parkin RBR E3 ubiquitin protein ligase 0.0196558
UTRN utrophin 0.0196194
NFIB nuclear factor I/B 0.0195379
FBXL7 F-box and leucine-rich repeat protein 7 0.0194708
TRIM9 tripartite motif containing 9 0.0193301
DENND1A DENN/MADD domain containing 1A 0.0193294
WWOX WW domain containing oxidoreductase 0.0192767
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0192061
SFPQ splicing factor proline/glutamine-rich 0.0191471
ARB2A ARB2 cotranscriptional regulator A 0.0191407
CDK19 cyclin-dependent kinase 19 0.0189937
TBC1D5 TBC1 domain family, member 5 0.0189918
FRMD6 FERM domain containing 6 0.0189636
ENO1 enolase 1, (alpha) 0.0186944
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0184599
EIF4B eukaryotic translation initiation factor 4B 0.0182698
RPL4 ribosomal protein L4 0.0181459
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.01812
OGA O-GlcNAcase 0.0178888
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.0174358
COL5A2 collagen, type V, alpha 2 0.0173996
ARHGAP21 Rho GTPase activating protein 21 0.0173981
YEATS2 YEATS domain containing 2 0.0173515
FLNB filamin B, beta 0.0167854
NSD1 nuclear receptor binding SET domain protein 1 0.0167808
FOXN3 forkhead box N3 0.0164344
PLS3 plastin 3 0.016126
PDGFC platelet derived growth factor C 0.0160956
SAMD4A sterile alpha motif domain containing 4A 0.0159965
IGF2 insulin-like growth factor 2 0.015992
NLN neurolysin (metallopeptidase M3 family) 0.0157047
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0156753
ITGAV integrin, alpha V 0.0156342
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.015606
POTEF POTE ankyrin domain family, member F 0.0155288
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.015458
BLTP1 bridge-like lipid transfer protein family member 1 0.0152373
NEMP1 nuclear envelope integral membrane protein 1 0.0152064
ATP11A ATPase, class VI, type 11A 0.0151262
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.0150167
OSBPL10 oxysterol binding protein-like 10 0.0149158
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0147512
TET2 tet methylcytosine dioxygenase 2 0.0146637
TMSB4X thymosin beta 4, X-linked 0.0146239
TRIO trio Rho guanine nucleotide exchange factor 0.0145951

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.146346
PTMA prothymosin, alpha -0.121196
VIM vimentin -0.105643
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0985855
MT2A metallothionein 2A -0.0748623
RPS6 ribosomal protein S6 -0.0729254
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0658501
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0656597
UBC ubiquitin C -0.0655325
RPS8 ribosomal protein S8 -0.0622784
IER3 immediate early response 3 -0.0591374
TMSB10 thymosin beta 10 -0.0558531
RPS27A ribosomal protein S27a -0.0533785
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0529954
RPLP1 ribosomal protein, large, P1 -0.051614
PDIA3 protein disulfide isomerase family A, member 3 -0.0502079
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0451465
TPT1 tumor protein, translationally-controlled 1 -0.0448214
RPS23 ribosomal protein S23 -0.0441153
RPS24 ribosomal protein S24 -0.0439063
RPL23 ribosomal protein L23 -0.0431586
RPL34 ribosomal protein L34 -0.0430249
CANX calnexin -0.0419111
CALR calreticulin -0.0393111
RPLP2 ribosomal protein, large, P2 -0.0379198
B2M beta-2-microglobulin -0.0378668
HMGB2 high mobility group box 2 -0.037841
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0377589
RAD21 RAD21 homolog (S. pombe) -0.0374733
HMGA1 high mobility group AT-hook 1 -0.0371603
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0365416
HMGB1 high mobility group box 1 -0.0350032
GOLGA4 golgin A4 -0.0340596
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0336762
RPL31 ribosomal protein L31 -0.0335792
NAP1L1 nucleosome assembly protein 1-like 1 -0.0321668
RPL35A ribosomal protein L35a -0.0321173
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0315508
RPL12 ribosomal protein L12 -0.0313594
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.031334
PEG10 paternally expressed 10 -0.0313045
RPL37A ribosomal protein L37a -0.0311711
RPL8 ribosomal protein L8 -0.0309041
PTK2 protein tyrosine kinase 2 -0.0307839
KTN1 kinectin 1 (kinesin receptor) -0.0305114
RPS13 ribosomal protein S13 -0.0300463
PDIA6 protein disulfide isomerase family A, member 6 -0.0287925
RPL26 ribosomal protein L26 -0.0287604
MATR3 matrin 3 -0.028601
NT5C2 5'-nucleotidase, cytosolic II -0.0285235
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0283638
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0281026
PUM2 pumilio RNA-binding family member 2 -0.0278115
RPS19 ribosomal protein S19 -0.0273276
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.0273202
DEK DEK proto-oncogene -0.0272077
FTL ferritin, light polypeptide -0.027134
PDIA4 protein disulfide isomerase family A, member 4 -0.0268182
RPL28 ribosomal protein L28 -0.0266863
DLG1 discs, large homolog 1 (Drosophila) -0.0264947
SMC4 structural maintenance of chromosomes 4 -0.0264938
RPL36 ribosomal protein L36 -0.0264402
RPS14 ribosomal protein S14 -0.0262592
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0261154
EIF1 eukaryotic translation initiation factor 1 -0.0260676
RPS10 ribosomal protein S10 -0.0260056
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0252351
CCNI cyclin I -0.0249167
YBX1 Y box binding protein 1 -0.0241792
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0240976
HDLBP high density lipoprotein binding protein -0.0240109
RBM25 RNA binding motif protein 25 -0.0238799
ENAH enabled homolog (Drosophila) -0.023873
RPL32 ribosomal protein L32 -0.0238384
RPL11 ribosomal protein L11 -0.0235605
RPL9 ribosomal protein L9 -0.0235475
NPR2 natriuretic peptide receptor 2 -0.0234946
RPS3 ribosomal protein S3 -0.0233353
H3-3B H3.3 histone B -0.0232708
FUBP1 far upstream element (FUSE) binding protein 1 -0.0232629
RPS25 ribosomal protein S25 -0.022965
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0229643
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0229557
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0228864
HLA-B major histocompatibility complex, class I, B -0.0227728
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.0227472
OSBPL8 oxysterol binding protein-like 8 -0.0225068
FUS FUS RNA binding protein -0.0225051
RHEB Ras homolog enriched in brain -0.0225003
RPS11 ribosomal protein S11 -0.0223834
RPL38 ribosomal protein L38 -0.0222316
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0221479
SEPTIN7 septin 7 -0.0217598
TUBA1B tubulin, alpha 1b -0.0217205
RPL19 ribosomal protein L19 -0.0216285
KMT2E lysine (K)-specific methyltransferase 2E -0.021606
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.021317
TPM4 tropomyosin 4 -0.0213004
ZFAND3 zinc finger, AN1-type domain 3 -0.021255
TPX2 TPX2, microtubule-associated -0.0212446