Gallic acid_C-33 A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in C-33 A cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ACTG1 actin gamma 1 0.151489
STAT1 signal transducer and activator of transcription 1, 91kDa 0.108624
ERBB4 erb-b2 receptor tyrosine kinase 4 0.0911228
MKI67 marker of proliferation Ki-67 0.0892365
ENO1 enolase 1, (alpha) 0.0892199
COL5A2 collagen, type V, alpha 2 0.0851953
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0824702
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0818785
ZNF608 zinc finger protein 608 0.078359
CENPF centromere protein F, 350/400kDa 0.0676123
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.0659529
RPL3 ribosomal protein L3 0.0610083
SHROOM3 shroom family member 3 0.0590128
RAD51B RAD51 paralog B 0.0553878
RPL4 ribosomal protein L4 0.0542819
HSPA8 heat shock 70kDa protein 8 0.0538014
EIF4B eukaryotic translation initiation factor 4B 0.0537072
ADAR adenosine deaminase, RNA-specific 0.052005
OSBPL10 oxysterol binding protein-like 10 0.0477297
USP9X ubiquitin specific peptidase 9, X-linked 0.0474679
CKAP5 cytoskeleton associated protein 5 0.0461138
CDH18 cadherin 18, type 2 0.0459863
TENM3 teneurin transmembrane protein 3 0.0458526
TBC1D5 TBC1 domain family, member 5 0.0446293
WLS wntless Wnt ligand secretion mediator 0.0442836
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.044186
SRSF4 serine/arginine-rich splicing factor 4 0.0434599
DCDC2 doublecortin domain containing 2 0.0425244
TOX thymocyte selection-associated high mobility group box 0.0420088
RRM2 ribonucleotide reductase M2 0.0415398
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0414665
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0414544
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0414185
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0411126
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.0399704
ATG10 autophagy related 10 0.0389561
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0386704
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.0382624
RPS2 ribosomal protein S2 0.0372701
IFI6 interferon, alpha-inducible protein 6 0.036739
PTPRG protein tyrosine phosphatase, receptor type, G 0.0364313
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0363108
NEBL nebulette 0.0350491
CENPE centromere protein E, 312kDa 0.034736
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.03367
MACF1 microtubule-actin crosslinking factor 1 0.0328627
PCM1 pericentriolar material 1 0.0318868
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.031667
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0311877
CARD18 caspase recruitment domain family, member 18 0.031142
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0306448
PGK1 phosphoglycerate kinase 1 0.0302948
POTEF POTE ankyrin domain family, member F 0.0301969
RPS3 ribosomal protein S3 0.0301596
PHACTR4 phosphatase and actin regulator 4 0.0293071
CEP250 centrosomal protein 250kDa 0.0292311
ZNF644 zinc finger protein 644 0.0292224
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0291477
RPLP1 ribosomal protein, large, P1 0.0283805
SMC1A structural maintenance of chromosomes 1A 0.0283348
ZNF146 zinc finger protein 146 0.0280088
TOP2B topoisomerase (DNA) II beta 180kDa 0.0278784
THRAP3 thyroid hormone receptor associated protein 3 0.0275724
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.0274924
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0273163
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0271583
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.0269267
RBBP7 retinoblastoma binding protein 7 0.026908
ATP11A ATPase, class VI, type 11A 0.0267213
PRICKLE1 prickle homolog 1 (Drosophila) 0.0266831
FAT1 FAT atypical cadherin 1 0.0265892
RIGI RNA sensor RIG-I 0.0262005
CEP112 centrosomal protein 112kDa 0.0260822
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.0259625
YAP1 Yes-associated protein 1 0.025877
RNF213 ring finger protein 213 0.0257616
WWOX WW domain containing oxidoreductase 0.0255617
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0252914
NSD1 nuclear receptor binding SET domain protein 1 0.0251271
WNK1 WNK lysine deficient protein kinase 1 0.0250051
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0249698
TPR translocated promoter region, nuclear basket protein 0.024754
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0246763
PRRC2B proline-rich coiled-coil 2B 0.024552
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0244677
RPL27 ribosomal protein L27 0.024431
MATR3 matrin 3 0.0244172
HMGB2 high mobility group box 2 0.0242151
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0241646
ILF3 interleukin enhancer binding factor 3, 90kDa 0.0236914
BABAM2 BRISC and BRCA1 A complex member 2 0.0233215
MNMIP1 manchette microtubule inner protein 1 0.0233085
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0232889
KDM1A lysine (K)-specific demethylase 1A 0.023258
PAQR7 progestin and adipoQ receptor family member VII 0.0231071
KPNB1 karyopherin (importin) beta 1 0.0228586
ATP5F1A ATP synthase F1 subunit alpha 0.022614
CSDE1 cold shock domain containing E1, RNA-binding 0.0225846
CNTRL centriolin 0.0225001
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.0224211

decreased expression

Symbol Name Standardized Value
UBC ubiquitin C -0.154185
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.127026
NR4A3 nuclear receptor subfamily 4, group A, member 3 -0.0947701
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0920511
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0835758
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0783902
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0780512
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0698258
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0677605
SLIT2 slit homolog 2 (Drosophila) -0.0643891
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0618621
SPDYA speedy/RINGO cell cycle regulator family member A -0.0573128
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0548386
RPS27A ribosomal protein S27a -0.0508182
TMSB10 thymosin beta 10 -0.0506218
RPS6 ribosomal protein S6 -0.0503413
SLF1 SMC5-SMC6 complex localization factor 1 -0.0483306
RPS5 ribosomal protein S5 -0.0482408
RPL23 ribosomal protein L23 -0.0463209
RPS11 ribosomal protein S11 -0.0450426
RPS24 ribosomal protein S24 -0.0447053
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -0.0443776
WDR45B WD repeat domain 45B -0.0438954
VCL vinculin -0.043275
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0424029
TTC3 tetratricopeptide repeat domain 3 -0.0413387
RPL34 ribosomal protein L34 -0.0402592
HMGA1 high mobility group AT-hook 1 -0.0389623
PDIA3 protein disulfide isomerase family A, member 3 -0.0385676
SLC38A2 solute carrier family 38, member 2 -0.0380818
RPL32 ribosomal protein L32 -0.037764
JUN jun proto-oncogene -0.0373301
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.037132
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.0370906
WSB1 WD repeat and SOCS box containing 1 -0.0369026
NUP58 nucleoporin 58 -0.0365631
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0354345
RAB1A RAB1A, member RAS oncogene family -0.0351681
RAP1B RAP1B, member of RAS oncogene family -0.0351229
SEC31A SEC31 homolog A (S. cerevisiae) -0.0348837
ZFAND3 zinc finger, AN1-type domain 3 -0.0347092
SNX14 sorting nexin 14 -0.0346846
ARB2A ARB2 cotranscriptional regulator A -0.0345449
MCTP1 multiple C2 domains, transmembrane 1 -0.0342213
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0341343
EMP1 epithelial membrane protein 1 -0.03412
VDAC1 voltage-dependent anion channel 1 -0.0340807
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0336802
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0333938
H1-0 H1.0 linker histone -0.033326
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0333095
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.0329158
FOXO3 forkhead box O3 -0.0329034
KMT2E lysine (K)-specific methyltransferase 2E -0.0321771
HMGB1 high mobility group box 1 -0.0320816
TRIO trio Rho guanine nucleotide exchange factor -0.0320484
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0320127
NBEAL1 neurobeachin-like 1 -0.0319294
RPS15 ribosomal protein S15 -0.0317557
EPC1 enhancer of polycomb homolog 1 (Drosophila) -0.0309492
CCNI cyclin I -0.0308766
SSBP2 single-stranded DNA binding protein 2 -0.0307104
HOMER1 homer scaffolding protein 1 -0.0304383
EEF1G eukaryotic translation elongation factor 1 gamma -0.0300803
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0300732
VMP1 vacuole membrane protein 1 -0.0296028
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0292151
EFNA5 ephrin-A5 -0.0289184
TPT1 tumor protein, translationally-controlled 1 -0.028902
RLF rearranged L-myc fusion -0.0288476
TBC1D32 TBC1 domain family, member 32 -0.0288058
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0287678
CALU calumenin -0.0285537
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0283111
FXR1 fragile X mental retardation, autosomal homolog 1 -0.0281435
KIAA1958 KIAA1958 -0.0280524
SETD5 SET domain containing 5 -0.0280243
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0278388
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0278244
RBM25 RNA binding motif protein 25 -0.0277281
ESYT2 extended synaptotagmin-like protein 2 -0.0276986
ATP9A ATPase, class II, type 9A -0.0276448
MED14 mediator complex subunit 14 -0.0274148
RCC1 regulator of chromosome condensation 1 -0.0271115
ANKRD12 ankyrin repeat domain 12 -0.0264299
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.026408
CANX calnexin -0.0263466
JARID2 jumonji, AT rich interactive domain 2 -0.0263298
AEBP2 AE binding protein 2 -0.0262905
SPAG9 sperm associated antigen 9 -0.0262509
FUS FUS RNA binding protein -0.0262076
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0261985
B2M beta-2-microglobulin -0.0261235
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0258274
GARS1 glycyl-tRNA synthetase 1 -0.0258266
STAU1 staufen double-stranded RNA binding protein 1 -0.0254713
TTC17 tetratricopeptide repeat domain 17 -0.025466
RPL9 ribosomal protein L9 -0.0250338
RNMT RNA (guanine-7-) methyltransferase -0.0250301
SBF2 SET binding factor 2 -0.0248719