Gallic acid_C32 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in C32 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FN1 fibronectin 1 0.302414
GPC6 glypican 6 0.0955726
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0856352
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0616661
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.0574869
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0509994
FMN1 formin 1 0.0470954
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.0469539
WWTR1 WW domain containing transcription regulator 1 0.0464235
NPAS2 neuronal PAS domain protein 2 0.0453911
PRELID2 PRELI domain containing 2 0.0432882
ENO1 enolase 1, (alpha) 0.0424953
LEF1 lymphoid enhancer-binding factor 1 0.0406023
AHNAK AHNAK nucleoprotein 0.0400327
SETBP1 SET binding protein 1 0.0376694
NPC1 Niemann-Pick disease, type C1 0.0374705
MYH9 myosin, heavy chain 9, non-muscle 0.0358352
PHC2 polyhomeotic homolog 2 (Drosophila) 0.0349132
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0342183
ITGB8 integrin, beta 8 0.032357
ZYX zyxin 0.0311012
IGFBP3 insulin-like growth factor binding protein 3 0.0307724
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0303603
ACTN1 actinin, alpha 1 0.0301545
PI15 peptidase inhibitor 15 0.029974
DST dystonin 0.0299506
AFDN afadin, adherens junction formation factor 0.029187
APP amyloid beta (A4) precursor protein 0.0281904
ASPH aspartate beta-hydroxylase 0.0270587
AHR aryl hydrocarbon receptor 0.0253538
RCAN1 regulator of calcineurin 1 0.0248349
SMYD3 SET and MYND domain containing 3 0.0247226
MACF1 microtubule-actin crosslinking factor 1 0.0244346
MCL1 myeloid cell leukemia 1 0.0244049
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 0.0243475
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0243223
EXOC4 exocyst complex component 4 0.0230349
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.022968
NFE2L1 nuclear factor, erythroid 2-like 1 0.0229591
TSC22D1 TSC22 domain family, member 1 0.0223802
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0223762
LRMDA leucine rich melanocyte differentiation associated 0.0221218
ACTG1 actin gamma 1 0.0216458
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0211568
UTRN utrophin 0.0208629
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0204165
STRIP2 striatin interacting protein 2 0.02011
SPRED1 sprouty-related, EVH1 domain containing 1 0.0199301
COL19A1 collagen, type XIX, alpha 1 0.0195012
OSBPL10 oxysterol binding protein-like 10 0.0191083
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0190945
TNNC1 troponin C type 1 (slow) 0.0186032
RPL3 ribosomal protein L3 0.018271
CDH19 cadherin 19, type 2 0.018141
EFCAB13 EF-hand calcium binding domain 13 0.0179122
RAD51B RAD51 paralog B 0.0177162
TPR translocated promoter region, nuclear basket protein 0.0171926
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0170798
APLP2 amyloid beta (A4) precursor-like protein 2 0.0168769
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0162547
ADAM19 ADAM metallopeptidase domain 19 0.0162276
SHROOM4 shroom family member 4 0.0161647
FRMD4A FERM domain containing 4A 0.0160518
RUNX1 runt-related transcription factor 1 0.0158813
SAMD4A sterile alpha motif domain containing 4A 0.0157742
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.015739
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.0154723
VCL vinculin 0.015346
PLEC plectin 0.0153433
SOX13 SRY (sex determining region Y)-box 13 0.0152687
NRP2 neuropilin 2 0.0152686
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.0151954
YAP1 Yes-associated protein 1 0.0151523
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 0.0150246
ABHD17C abhydrolase domain containing 17C 0.0148831
VMP1 vacuole membrane protein 1 0.0146174
NIBAN2 niban apoptosis regulator 2 0.0144845
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.014363
ZNF608 zinc finger protein 608 0.0142904
TMEM255B transmembrane protein 255B 0.0141426
IL6ST interleukin 6 signal transducer 0.0140905
EIF4H eukaryotic translation initiation factor 4H 0.0140628
SVIL supervillin 0.014025
BZW1 basic leucine zipper and W2 domains 1 0.0136173
BACE2 beta-site APP-cleaving enzyme 2 0.0136005
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.013329
ERRFI1 ERBB receptor feedback inhibitor 1 0.0130972
FMNL2 formin-like 2 0.0129728
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0129352
DSTYK dual serine/threonine and tyrosine protein kinase 0.0126984
LPP LIM domain containing preferred translocation partner in lipoma 0.0125916
AOPEP aminopeptidase O (putative) 0.0125051
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0124512
NRIP1 nuclear receptor interacting protein 1 0.0124032
ETV6 ets variant 6 0.0122616
PDLIM5 PDZ and LIM domain 5 0.0122398
MBD5 methyl-CpG binding domain protein 5 0.0122081
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0121514
CEMIP2 cell migration inducing hyaluronidase 2 0.0121264
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0120763

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.46156
VIM vimentin -0.171904
NDRG1 N-myc downstream regulated 1 -0.0910285
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.089807
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0889263
TMSB10 thymosin beta 10 -0.0855415
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0819162
DCT dopachrome tautomerase -0.0802183
HLA-B major histocompatibility complex, class I, B -0.0772791
S100A6 S100 calcium binding protein A6 -0.0743123
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0674933
HILPDA hypoxia inducible lipid droplet-associated -0.062094
VGF VGF nerve growth factor inducible -0.0620384
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0597168
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0560514
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0551567
PTMA prothymosin, alpha -0.0523835
GDF15 growth differentiation factor 15 -0.0499908
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0479672
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0448037
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.0432352
TAGLN2 transgelin 2 -0.0427914
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0424813
PHF21A PHD finger protein 21A -0.0421208
WSB1 WD repeat and SOCS box containing 1 -0.0420536
PDIA3 protein disulfide isomerase family A, member 3 -0.041839
TPI1 triosephosphate isomerase 1 -0.0417588
FTL ferritin, light polypeptide -0.0414884
INSIG1 insulin induced gene 1 -0.0405925
CALD1 caldesmon 1 -0.040487
CTSD cathepsin D -0.0404092
S100A9 S100 calcium binding protein A9 -0.0401192
VDAC1 voltage-dependent anion channel 1 -0.0393333
GNAS GNAS complex locus -0.0391576
IER3 immediate early response 3 -0.0376629
RNF24 ring finger protein 24 -0.0373621
TRIM2 tripartite motif containing 2 -0.0369022
TMEM123 transmembrane protein 123 -0.0366403
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0359372
LGALS3 lectin, galactoside-binding, soluble, 3 -0.0356613
KMT2E lysine (K)-specific methyltransferase 2E -0.0351438
CENPF centromere protein F, 350/400kDa -0.0348062
PKM pyruvate kinase, muscle -0.0346961
HSPB1 heat shock 27kDa protein 1 -0.0346594
WDR45B WD repeat domain 45B -0.0344571
RHEB Ras homolog enriched in brain -0.033731
CDC73 cell division cycle 73 -0.0331976
NLGN1 neuroligin 1 -0.0329242
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0329109
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0324372
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0324111
TPT1 tumor protein, translationally-controlled 1 -0.0319929
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0315619
LMNA lamin A/C -0.031234
RPLP1 ribosomal protein, large, P1 -0.0310047
CALU calumenin -0.030768
RPL35A ribosomal protein L35a -0.0303663
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0298956
PGK1 phosphoglycerate kinase 1 -0.0296585
EGR1 early growth response 1 -0.0296199
IFITM3 interferon induced transmembrane protein 3 -0.0294108
RPS19 ribosomal protein S19 -0.0286552
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0280165
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0279771
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.0279686
RPS8 ribosomal protein S8 -0.0279113
KMT2C lysine (K)-specific methyltransferase 2C -0.0279045
MTPN myotrophin -0.027847
B2M beta-2-microglobulin -0.0276557
RPL34 ribosomal protein L34 -0.0274132
CD109 CD109 molecule -0.0273107
ZNF292 zinc finger protein 292 -0.0272575
FYN FYN proto-oncogene, Src family tyrosine kinase -0.0271512
RPS6 ribosomal protein S6 -0.0269528
UBC ubiquitin C -0.0268334
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0268063
KDM5B lysine (K)-specific demethylase 5B -0.0265974
ADM adrenomedullin -0.0263992
GOLGA4 golgin A4 -0.0262505
NPR2 natriuretic peptide receptor 2 -0.0260128
SETD5 SET domain containing 5 -0.0258018
PTK2 protein tyrosine kinase 2 -0.0256445
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0255182
S100A10 S100 calcium binding protein A10 -0.0252285
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0250827
CYB5R3 cytochrome b5 reductase 3 -0.0249649
MTDH metadherin -0.0247129
NAV3 neuron navigator 3 -0.0245775
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0243851
SCARB1 scavenger receptor class B, member 1 -0.0242223
MFSD12 major facilitator superfamily domain containing 12 -0.0241042
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.024042
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.023926
PFN1 profilin 1 -0.0236095
HMGA1 high mobility group AT-hook 1 -0.023478
RAB7A RAB7A, member RAS oncogene family -0.0234162
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.023361
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0233343
RPS24 ribosomal protein S24 -0.0233335
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0231823