Gallic acid_CFPAC-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in CFPAC-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
SAMD4A sterile alpha motif domain containing 4A 0.176012
AHNAK AHNAK nucleoprotein 0.154967
LAMB3 laminin, beta 3 0.117853
SPTBN1 spectrin, beta, non-erythrocytic 1 0.115222
APP amyloid beta (A4) precursor protein 0.112122
CP ceruloplasmin (ferroxidase) 0.110785
SYNE2 spectrin repeat containing, nuclear envelope 2 0.101367
EFNA5 ephrin-A5 0.095749
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0914286
IGFBP3 insulin-like growth factor binding protein 3 0.0857601
ENO1 enolase 1, (alpha) 0.0799757
MCL1 myeloid cell leukemia 1 0.0789618
DST dystonin 0.0771285
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0737369
BZW1 basic leucine zipper and W2 domains 1 0.0727918
FTH1 ferritin, heavy polypeptide 1 0.0701366
LMO7 LIM domain 7 0.0675932
APLP2 amyloid beta (A4) precursor-like protein 2 0.0660427
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0643703
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0641815
FNDC3B fibronectin type III domain containing 3B 0.0621724
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0607817
TMC5 transmembrane channel-like 5 0.0588174
DTNA dystrobrevin, alpha 0.0586614
AHNAK2 AHNAK nucleoprotein 2 0.0585435
MACF1 microtubule-actin crosslinking factor 1 0.0573358
EZR ezrin 0.056655
GRB10 growth factor receptor-bound protein 10 0.0558409
ANXA2 annexin A2 0.0555395
BACE2 beta-site APP-cleaving enzyme 2 0.0554015
LAMC2 laminin, gamma 2 0.0539696
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0531873
BCAR3 breast cancer anti-estrogen resistance 3 0.0526514
PARD3 par-3 family cell polarity regulator 0.051552
PDE4D phosphodiesterase 4D, cAMP-specific 0.0478123
NPEPPS aminopeptidase puromycin sensitive 0.0469963
CANX calnexin 0.0469777
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0461586
GOLGB1 golgin B1 0.0461002
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0460889
MYH9 myosin, heavy chain 9, non-muscle 0.0460133
RNF213 ring finger protein 213 0.0453025
EIF1 eukaryotic translation initiation factor 1 0.0450096
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0449741
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0438117
ASPH aspartate beta-hydroxylase 0.0430233
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0418239
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0417963
IGF1R insulin-like growth factor 1 receptor 0.0417208
KMT2C lysine (K)-specific methyltransferase 2C 0.0409201
OPTN optineurin 0.0407414
SYNRG synergin, gamma 0.0407002
KANSL1 KAT8 regulatory NSL complex subunit 1 0.0404784
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0384846
HLA-E major histocompatibility complex, class I, E 0.0382647
MX1 MX dynamin-like GTPase 1 0.0380549
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.0379636
ESYT2 extended synaptotagmin-like protein 2 0.0373434
UBC ubiquitin C 0.0360682
PHF3 PHD finger protein 3 0.0360049
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0359513
RAB1A RAB1A, member RAS oncogene family 0.0347719
PDIA3 protein disulfide isomerase family A, member 3 0.0345885
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0342378
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0331218
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.0326805
MYO1E myosin IE 0.0326649
PLEC plectin 0.0324704
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0324656
SLC35F5 solute carrier family 35, member F5 0.032275
MYO5B myosin VB 0.0322246
PPARD peroxisome proliferator-activated receptor delta 0.0321596
TSC22D2 TSC22 domain family, member 2 0.0320253
HOOK2 hook microtubule-tethering protein 2 0.0318667
RCOR1 REST corepressor 1 0.0318354
SPAG9 sperm associated antigen 9 0.0315439
NPAS2 neuronal PAS domain protein 2 0.0315384
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0314385
DOCK5 dedicator of cytokinesis 5 0.0312168
NUMB numb homolog (Drosophila) 0.031132
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0308151
CEMIP cell migration inducing protein, hyaluronan binding 0.0306712
LPP LIM domain containing preferred translocation partner in lipoma 0.0305263
TXNIP thioredoxin interacting protein 0.0295092
MEF2A myocyte enhancer factor 2A 0.0292711
MCU mitochondrial calcium uniporter 0.0287607
AFF4 AF4/FMR2 family, member 4 0.0286508
DSPP dentin sialophosphoprotein 0.028335
EXT1 exostosin glycosyltransferase 1 0.0282959
TPM4 tropomyosin 4 0.0281327
PGK1 phosphoglycerate kinase 1 0.0280649
JUN jun proto-oncogene 0.027738
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0277091
EHBP1 EH domain binding protein 1 0.0276844
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0272979
TBC1D22A TBC1 domain family, member 22A 0.0272223
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0269812
BARX2 BARX homeobox 2 0.0269368
KDM2A lysine (K)-specific demethylase 2A 0.0269151
CFLAR CASP8 and FADD-like apoptosis regulator 0.0264915

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -0.174886
TMSB10 thymosin beta 10 -0.145831
NDRG1 N-myc downstream regulated 1 -0.11568
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0990623
HMGA1 high mobility group AT-hook 1 -0.0818857
RPL23 ribosomal protein L23 -0.0792888
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0620492
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0612426
RPL9 ribosomal protein L9 -0.0589226
TPM1 tropomyosin 1 (alpha) -0.0575281
RPLP1 ribosomal protein, large, P1 -0.0540987
TOP1 topoisomerase (DNA) I -0.0521531
RPS24 ribosomal protein S24 -0.051725
RPS8 ribosomal protein S8 -0.0507077
RPL11 ribosomal protein L11 -0.0504908
RPL35A ribosomal protein L35a -0.0498728
RPL34 ribosomal protein L34 -0.049123
CCNL1 cyclin L1 -0.0489186
TPT1 tumor protein, translationally-controlled 1 -0.0486465
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0477853
RPS19 ribosomal protein S19 -0.0456215
RTN4 reticulon 4 -0.045145
RPL19 ribosomal protein L19 -0.0443718
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0436203
ISG15 ISG15 ubiquitin-like modifier -0.0435802
RPS23 ribosomal protein S23 -0.0421898
MCTP1 multiple C2 domains, transmembrane 1 -0.042042
FAM162A family with sequence similarity 162, member A -0.0416104
RPS6 ribosomal protein S6 -0.0413294
RPLP0 ribosomal protein, large, P0 -0.04121
ALCAM activated leukocyte cell adhesion molecule -0.0389608
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0383196
IFI27 interferon, alpha-inducible protein 27 -0.0380415
AREG amphiregulin -0.0378745
RPS21 ribosomal protein S21 -0.0363294
TMSB4X thymosin beta 4, X-linked -0.0360555
ACTG1 actin gamma 1 -0.0352016
MT1X metallothionein 1X -0.0351065
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0346234
KLF6 Kruppel-like factor 6 -0.034602
RBM25 RNA binding motif protein 25 -0.034493
RPS29 ribosomal protein S29 -0.0335131
RPL26 ribosomal protein L26 -0.0333953
IER3 immediate early response 3 -0.0333516
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0316688
TXNRD1 thioredoxin reductase 1 -0.0316156
EREG epiregulin -0.0315197
RACK1 receptor for activated C kinase 1 -0.0310885
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.0307342
PFN1 profilin 1 -0.0304297
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -0.0303689
SMC4 structural maintenance of chromosomes 4 -0.0295376
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.0294411
RPL5 ribosomal protein L5 -0.0278107
HPCAL1 hippocalcin-like 1 -0.026769
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0267647
TMBIM6 transmembrane BAX inhibitor motif containing 6 -0.0267485
RPS25 ribosomal protein S25 -0.0266868
RPLP2 ribosomal protein, large, P2 -0.0266823
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0265175
AGRN agrin -0.0262142
CENPF centromere protein F, 350/400kDa -0.0262103
LAMA5 laminin, alpha 5 -0.0261515
PTMA prothymosin, alpha -0.0256885
CENPE centromere protein E, 312kDa -0.0256091
ADAM9 ADAM metallopeptidase domain 9 -0.0255611
ARHGAP26 Rho GTPase activating protein 26 -0.025545
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0254459
LAMA4 laminin, alpha 4 -0.0253361
RPS14 ribosomal protein S14 -0.025125
PABPN1 poly(A) binding protein, nuclear 1 -0.0247142
SLC38A2 solute carrier family 38, member 2 -0.0246147
RPS17 ribosomal protein S17 -0.0244642
GNAS GNAS complex locus -0.0243229
ATP5F1E ATP synthase F1 subunit epsilon -0.024281
RPS5 ribosomal protein S5 -0.0242734
EEF1G eukaryotic translation elongation factor 1 gamma -0.0242079
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.0241733
DUSP5 dual specificity phosphatase 5 -0.023977
LMNA lamin A/C -0.0238476
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0231595
GARS1 glycyl-tRNA synthetase 1 -0.0230018
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0229779
LOC102724023 ES1 protein homolog, mitochondrial -0.0228251
S100A6 S100 calcium binding protein A6 -0.0227152
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0226699
TUBB tubulin, beta class I -0.022626
RPS3 ribosomal protein S3 -0.0226049
RPS16 ribosomal protein S16 -0.0224392
FOSL1 FOS-like antigen 1 -0.0224274
FTL ferritin, light polypeptide -0.022362
DEK DEK proto-oncogene -0.0222631
F3 coagulation factor III (thromboplastin, tissue factor) -0.0221376
LY6E lymphocyte antigen 6 complex, locus E -0.0219542
FRMD5 FERM domain containing 5 -0.0218927
RPS12 ribosomal protein S12 -0.0218169
FBXL5 F-box and leucine-rich repeat protein 5 -0.0217217
MIS18BP1 MIS18 binding protein 1 -0.0216368
GLS2 glutaminase 2 (liver, mitochondrial) -0.0213528
RPS27A ribosomal protein S27a -0.0212449