Gallic acid_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in CHP-212 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.104716
NALF1 NALCN channel auxiliary factor 1 0.0901124
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 0.0825664
ANTXR1 anthrax toxin receptor 1 0.0824488
TRIO trio Rho guanine nucleotide exchange factor 0.0759548
TPST1 tyrosylprotein sulfotransferase 1 0.075893
PTPRD protein tyrosine phosphatase, receptor type, D 0.0681487
EXT1 exostosin glycosyltransferase 1 0.0619288
LSAMP limbic system-associated membrane protein 0.0613
SOS1 son of sevenless homolog 1 (Drosophila) 0.0588972
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.0581117
ITPRID2 ITPR interacting domain containing 2 0.0572104
TENM4 teneurin transmembrane protein 4 0.0523276
PLAT plasminogen activator, tissue 0.0519544
PDE10A phosphodiesterase 10A 0.049768
FMN1 formin 1 0.0484567
THSD4 thrombospondin, type I, domain containing 4 0.0473844
CEMIP cell migration inducing protein, hyaluronan binding 0.0469169
ZBTB20 zinc finger and BTB domain containing 20 0.0459624
RNF213 ring finger protein 213 0.0433904
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0418728
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.041629
ARHGAP9 Rho GTPase activating protein 9 0.0414878
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0412438
DNMBP dynamin binding protein 0.0400868
KLHL13 kelch-like family member 13 0.038357
HSPA8 heat shock 70kDa protein 8 0.037801
EEF2 eukaryotic translation elongation factor 2 0.0373576
IGF1R insulin-like growth factor 1 receptor 0.0373318
NRG1 neuregulin 1 0.0372308
AKAP12 A kinase (PRKA) anchor protein 12 0.0369077
APP amyloid beta (A4) precursor protein 0.0366366
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.0353675
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0352229
PACS1 phosphofurin acidic cluster sorting protein 1 0.0344174
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0342213
PTEN phosphatase and tensin homolog 0.032898
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.0327655
NPAS2 neuronal PAS domain protein 2 0.0325599
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0322048
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.032092
SLITRK6 SLIT and NTRK-like family, member 6 0.0320822
SH3PXD2B SH3 and PX domains 2B 0.0318351
SYT1 synaptotagmin I 0.0318316
PTPRE protein tyrosine phosphatase, receptor type, E 0.0317841
MSI2 musashi RNA-binding protein 2 0.0317346
GREM2 gremlin 2, DAN family BMP antagonist 0.0313346
RPL4 ribosomal protein L4 0.0312944
ADGRG6 adhesion G protein-coupled receptor G6 0.0312874
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.031076
CDH10 cadherin 10, type 2 (T2-cadherin) 0.0310531
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0310296
ZFC3H1 zinc finger, C3H1-type containing 0.0306915
PDE4D phosphodiesterase 4D, cAMP-specific 0.0297483
ANGPT1 angiopoietin 1 0.0292846
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0291266
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0287133
SIK2 salt-inducible kinase 2 0.0285974
PDE3A phosphodiesterase 3A, cGMP-inhibited 0.0283037
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.0281637
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.0279347
FNDC3B fibronectin type III domain containing 3B 0.0274355
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0274295
SMAD3 SMAD family member 3 0.0273638
AMOTL1 angiomotin like 1 0.0271575
DSCAM Down syndrome cell adhesion molecule 0.0270509
PLPP1 phospholipid phosphatase 1 0.027
PCBP3 poly(rC) binding protein 3 0.0268731
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.026856
EIF4A1 eukaryotic translation initiation factor 4A1 0.0267276
MBNL2 muscleblind-like splicing regulator 2 0.0265933
AHR aryl hydrocarbon receptor 0.0261403
ZEB1 zinc finger E-box binding homeobox 1 0.0254583
RAD51B RAD51 paralog B 0.0252921
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.025237
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0252045
ATXN10 ataxin 10 0.0250332
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0247236
AOPEP aminopeptidase O (putative) 0.0244567
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0243256
MICU3 mitochondrial calcium uptake family, member 3 0.0243101
DGKH diacylglycerol kinase, eta 0.0242786
MACF1 microtubule-actin crosslinking factor 1 0.0239035
CHD9 chromodomain helicase DNA binding protein 9 0.0237373
TRPS1 trichorhinophalangeal syndrome I 0.0237261
MAP1B microtubule-associated protein 1B 0.0236431
MYH9 myosin, heavy chain 9, non-muscle 0.0235057
PTPRM protein tyrosine phosphatase, receptor type, M 0.0234389
AHNAK AHNAK nucleoprotein 0.0233282
CEMIP2 cell migration inducing hyaluronidase 2 0.0233087
GSE1 Gse1 coiled-coil protein 0.0231294
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0230422
DST dystonin 0.0230371
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0230311
PCNX1 pecanex 1 0.0229034
STXBP5 syntaxin binding protein 5 (tomosyn) 0.0226773
COL4A1 collagen, type IV, alpha 1 0.0222528
COL4A5 collagen, type IV, alpha 5 0.0222086
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0221914
GAB2 GRB2-associated binding protein 2 0.0220201

decreased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 -0.408417
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.153276
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.113493
RPS6 ribosomal protein S6 -0.0884935
PTMA prothymosin, alpha -0.0834692
VIM vimentin -0.0665465
VCL vinculin -0.0661055
RPL35A ribosomal protein L35a -0.062383
TMSB10 thymosin beta 10 -0.0595711
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0584062
RPLP1 ribosomal protein, large, P1 -0.0560334
NDRG1 N-myc downstream regulated 1 -0.0513112
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.050976
RPL34 ribosomal protein L34 -0.0497181
FTL ferritin, light polypeptide -0.0438108
TPT1 tumor protein, translationally-controlled 1 -0.0428908
RPL23 ribosomal protein L23 -0.0427922
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0415945
RPL38 ribosomal protein L38 -0.0403379
GOLGA4 golgin A4 -0.0385101
P4HB prolyl 4-hydroxylase, beta polypeptide -0.037298
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0372384
RPL19 ribosomal protein L19 -0.0366898
EGR1 early growth response 1 -0.0354994
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0345629
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0344416
RPL32 ribosomal protein L32 -0.0343886
RPS19 ribosomal protein S19 -0.0343492
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0342634
RPS15 ribosomal protein S15 -0.0336508
IER3 immediate early response 3 -0.0329605
RPS24 ribosomal protein S24 -0.0323299
RPL31 ribosomal protein L31 -0.0318204
WDR45B WD repeat domain 45B -0.0318182
LMNA lamin A/C -0.0314538
RPL36 ribosomal protein L36 -0.0309551
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0304431
CALD1 caldesmon 1 -0.0298445
MEIS2 Meis homeobox 2 -0.0291894
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0282339
ZCCHC7 zinc finger, CCHC domain containing 7 -0.027887
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -0.0277895
RPS29 ribosomal protein S29 -0.0276424
INTS6 integrator complex subunit 6 -0.0274067
STXBP4 syntaxin binding protein 4 -0.0270598
RAB7A RAB7A, member RAS oncogene family -0.0267282
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D -0.0262932
SQSTM1 sequestosome 1 -0.0261835
DCAF7 DDB1 and CUL4 associated factor 7 -0.0259708
CANX calnexin -0.0259145
RPS11 ribosomal protein S11 -0.0258831
TLE4 transducin-like enhancer of split 4 -0.0256196
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0256102
UBE2B ubiquitin-conjugating enzyme E2B -0.025067
RPL9 ribosomal protein L9 -0.0249653
ARID4B AT rich interactive domain 4B (RBP1-like) -0.024826
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0242374
RPS25 ribosomal protein S25 -0.0241657
HELZ helicase with zinc finger -0.0240719
MBNL1 muscleblind-like splicing regulator 1 -0.0238125
B2M beta-2-microglobulin -0.0236771
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0236726
RTN4 reticulon 4 -0.023624
NME2 NME/NM23 nucleoside diphosphate kinase 2 -0.0235946
MARCKS myristoylated alanine-rich protein kinase C substrate -0.023476
RPLP0 ribosomal protein, large, P0 -0.0232586
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0231578
SEC31A SEC31 homolog A (S. cerevisiae) -0.0229254
MYO1E myosin IE -0.0228333
PDLIM5 PDZ and LIM domain 5 -0.0227295
S100A9 S100 calcium binding protein A9 -0.0226703
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -0.022445
RPS21 ribosomal protein S21 -0.0222515
CCND1 cyclin D1 -0.0221505
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -0.0220329
RPS8 ribosomal protein S8 -0.0219772
ANKRD12 ankyrin repeat domain 12 -0.0216785
RNMT RNA (guanine-7-) methyltransferase -0.0212351
RPL36A ribosomal protein L36a -0.0211996
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 -0.0209764
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -0.0208047
SETD5 SET domain containing 5 -0.0208035
RPL37A ribosomal protein L37a -0.0207428
S100A6 S100 calcium binding protein A6 -0.0204617
NAP1L1 nucleosome assembly protein 1-like 1 -0.0203151
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0201872
JPT1 Jupiter microtubule associated homolog 1 -0.0201377
IGFBP3 insulin-like growth factor binding protein 3 -0.0200821
VDAC1 voltage-dependent anion channel 1 -0.0200636
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0200508
RSRC2 arginine/serine-rich coiled-coil 2 -0.0199886
KMT2E lysine (K)-specific methyltransferase 2E -0.0195231
SCAF11 SR-related CTD-associated factor 11 -0.019343
LIMA1 LIM domain and actin binding 1 -0.0192877
DSTN destrin (actin depolymerizing factor) -0.0191661
TPM4 tropomyosin 4 -0.0190941
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.0189483
NPEPPS aminopeptidase puromycin sensitive -0.0187934
RPS16 ribosomal protein S16 -0.0187758
RPL13A ribosomal protein L13a -0.0187397