Gallic acid_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in COLO 205 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.12033
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0995024
LMO7 LIM domain 7 0.0872069
RNF43 ring finger protein 43 0.0775034
SMAD3 SMAD family member 3 0.0767649
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0761603
RUNX1 runt-related transcription factor 1 0.0715858
FAT1 FAT atypical cadherin 1 0.0691269
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0681885
ITGA6 integrin, alpha 6 0.0667719
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0629053
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0623808
ABHD2 abhydrolase domain containing 2 0.0614365
ATP10B ATPase, class V, type 10B 0.0598981
MYH9 myosin, heavy chain 9, non-muscle 0.0521059
YAP1 Yes-associated protein 1 0.0502709
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0472666
MLPH melanophilin 0.0454066
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0449061
TSC22D1 TSC22 domain family, member 1 0.0443696
AHNAK AHNAK nucleoprotein 0.0440913
IFNGR1 interferon gamma receptor 1 0.0428659
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0426765
ASPH aspartate beta-hydroxylase 0.04262
NRIP1 nuclear receptor interacting protein 1 0.0420206
DST dystonin 0.0413952
PTBP3 polypyrimidine tract binding protein 3 0.0413847
SIPA1L2 signal-induced proliferation-associated 1 like 2 0.0397993
MSI2 musashi RNA-binding protein 2 0.0397323
SPRED1 sprouty-related, EVH1 domain containing 1 0.0387582
AOPEP aminopeptidase O (putative) 0.0384397
SH3PXD2A SH3 and PX domains 2A 0.0383474
PDZD8 PDZ domain containing 8 0.0381309
SORBS1 sorbin and SH3 domain containing 1 0.0365642
EPHB2 EPH receptor B2 0.0349794
TJP2 tight junction protein 2 0.0348677
ENO1 enolase 1, (alpha) 0.0344647
MACF1 microtubule-actin crosslinking factor 1 0.0343093
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0342137
IL20RA interleukin 20 receptor, alpha 0.0336687
PRSS3 protease, serine, 3 0.033567
TC2N tandem C2 domains, nuclear 0.0332003
DUSP16 dual specificity phosphatase 16 0.0330635
ZNRF3 zinc and ring finger 3 0.0323066
DSPP dentin sialophosphoprotein 0.0322566
CDHR2 cadherin-related family member 2 0.03135
ARGLU1 arginine and glutamate rich 1 0.0308021
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 0.0289805
POTEF POTE ankyrin domain family, member F 0.0287401
SHB Src homology 2 domain containing adaptor protein B 0.0285177
RNF149 ring finger protein 149 0.0275864
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0273389
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0272679
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0272661
MEIS2 Meis homeobox 2 0.0270462
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0269096
ADAM10 ADAM metallopeptidase domain 10 0.0266751
NIBAN2 niban apoptosis regulator 2 0.0265962
AFF1 AF4/FMR2 family, member 1 0.0261456
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0257386
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0256904
PLS1 plastin 1 0.025286
CEMIP cell migration inducing protein, hyaluronan binding 0.0252016
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0250477
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.0249144
CEMIP2 cell migration inducing hyaluronidase 2 0.0248517
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.0247574
TMEM62 transmembrane protein 62 0.0244671
ETV6 ets variant 6 0.0242431
PRSS22 protease, serine, 22 0.0240566
TXNIP thioredoxin interacting protein 0.0240199
CTNND1 catenin (cadherin-associated protein), delta 1 0.0238191
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0237304
SLK STE20-like kinase 0.0234058
FTH1 ferritin, heavy polypeptide 1 0.0233313
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0232687
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 0.0230308
TMEM45B transmembrane protein 45B 0.0228951
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0228162
SRRM2 serine/arginine repetitive matrix 2 0.0227584
ARHGAP26 Rho GTPase activating protein 26 0.0227442
DUSP4 dual specificity phosphatase 4 0.0224736
TOX3 TOX high mobility group box family member 3 0.022146
ACSL5 acyl-CoA synthetase long-chain family member 5 0.0220105
MYO5B myosin VB 0.0219351
DIAPH1 diaphanous-related formin 1 0.0217529
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0214645
MAP2K6 mitogen-activated protein kinase kinase 6 0.0213203
LMTK2 lemur tyrosine kinase 2 0.0211502
VEGFA vascular endothelial growth factor A 0.0206608
PELI1 pellino E3 ubiquitin protein ligase 1 0.0205942
ITM2B integral membrane protein 2B 0.0204735
PKM pyruvate kinase, muscle 0.0204207
PPARG peroxisome proliferator-activated receptor gamma 0.0200868
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0198595
RBM26 RNA binding motif protein 26 0.0197164
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.0196779
NCOR2 nuclear receptor corepressor 2 0.0196307
ARHGAP32 Rho GTPase activating protein 32 0.0195727
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0193132

decreased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 -0.225002
INTS6 integrator complex subunit 6 -0.141476
EGR1 early growth response 1 -0.13002
STAT1 signal transducer and activator of transcription 1, 91kDa -0.116445
LYZ lysozyme -0.114828
XAF1 XIAP associated factor 1 -0.112596
RIGI RNA sensor RIG-I -0.109613
VCL vinculin -0.103313
EPSTI1 epithelial stromal interaction 1 (breast) -0.0964836
SP100 SP100 nuclear antigen -0.0947308
RAB7A RAB7A, member RAS oncogene family -0.0915345
PTMA prothymosin, alpha -0.0881658
PLSCR2 phospholipid scramblase 2 -0.0847394
PLSCR1 phospholipid scramblase 1 -0.0800253
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0775675
HLA-B major histocompatibility complex, class I, B -0.0762948
NPSR1 neuropeptide S receptor 1 -0.075717
RNF213 ring finger protein 213 -0.074835
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0725386
ANXA2 annexin A2 -0.0721748
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0685165
SQSTM1 sequestosome 1 -0.068386
ANKRD10 ankyrin repeat domain 10 -0.0667592
NDRG1 N-myc downstream regulated 1 -0.0638753
MX2 MX dynamin-like GTPase 2 -0.0622852
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0607674
MUC20 mucin 20, cell surface associated -0.0595808
EZR ezrin -0.0592955
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0586625
PHF3 PHD finger protein 3 -0.0580524
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0562639
TM4SF1 transmembrane 4 L six family member 1 -0.056204
PERP PERP, TP53 apoptosis effector -0.0551092
TJP1 tight junction protein 1 -0.0541978
IFI6 interferon, alpha-inducible protein 6 -0.0539889
H1-0 H1.0 linker histone -0.049591
AREG amphiregulin -0.0494036
TM4SF19 transmembrane 4 L six family member 19 -0.0489476
SEC31A SEC31 homolog A (S. cerevisiae) -0.047658
RPL35A ribosomal protein L35a -0.0475867
EIF1 eukaryotic translation initiation factor 1 -0.0470077
HLA-E major histocompatibility complex, class I, E -0.046929
AHI1 Abelson helper integration site 1 -0.0462803
RPS6 ribosomal protein S6 -0.0460973
GOLGB1 golgin B1 -0.0457884
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0453897
PMP22 peripheral myelin protein 22 -0.0448881
MORF4L2 mortality factor 4 like 2 -0.0446576
GMDS GDP-mannose 4,6-dehydratase -0.0428743
BLZF1 basic leucine zipper nuclear factor 1 -0.0425524
RPL34 ribosomal protein L34 -0.0424695
RPS24 ribosomal protein S24 -0.0422516
RABGAP1L RAB GTPase activating protein 1-like -0.04193
HM13 histocompatibility (minor) 13 -0.04187
MX1 MX dynamin-like GTPase 1 -0.0417478
NCOA7 nuclear receptor coactivator 7 -0.0404565
IGFBP3 insulin-like growth factor binding protein 3 -0.0403486
HLA-C major histocompatibility complex, class I, C -0.0402934
IFIH1 interferon induced with helicase C domain 1 -0.0399315
SPAG9 sperm associated antigen 9 -0.0395931
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0390333
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0383869
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0383826
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0383442
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0381901
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.0376804
ARF1 ADP-ribosylation factor 1 -0.0373987
NF1 neurofibromin 1 -0.0369826
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0369691
RRBP1 ribosome binding protein 1 -0.0369496
JUN jun proto-oncogene -0.0368226
POU2F2 POU class 2 homeobox 2 -0.0363998
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0363955
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.036214
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0359691
ERBIN erbb2 interacting protein -0.0358774
RBM39 RNA binding motif protein 39 -0.0352162
UBAP2 ubiquitin associated protein 2 -0.035206
GNAS GNAS complex locus -0.0351638
UFM1 ubiquitin-fold modifier 1 -0.0350046
NABP1 nucleic acid binding protein 1 -0.0347921
MCTP1 multiple C2 domains, transmembrane 1 -0.0343968
ZNF292 zinc finger protein 292 -0.0343088
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -0.0342717
FTL ferritin, light polypeptide -0.0342697
RPL7L1 ribosomal protein L7-like 1 -0.0341878
TUFT1 tuftelin 1 -0.0327343
TMSB10 thymosin beta 10 -0.0325481
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0323669
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0322951
OASL 2'-5'-oligoadenylate synthetase-like -0.0319179
SLC38A2 solute carrier family 38, member 2 -0.0316674
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0313245
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0311229
EPCAM epithelial cell adhesion molecule -0.0310417
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0306015
MAP7 microtubule-associated protein 7 -0.0305343
PIBF1 progesterone immunomodulatory binding factor 1 -0.0304779
TSHZ2 teashirt zinc finger homeobox 2 -0.0303423
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0301319