Gallic acid_H4 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in H4 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.320579
AKAP12 A kinase (PRKA) anchor protein 12 0.074632
ENO1 enolase 1, (alpha) 0.060749
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0576581
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0572758
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0512183
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0500688
POTEF POTE ankyrin domain family, member F 0.0500183
NAV2 neuron navigator 2 0.0488707
NFE2L1 nuclear factor, erythroid 2-like 1 0.0475703
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0465242
MKI67 marker of proliferation Ki-67 0.0455085
MSN moesin 0.045357
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0429645
LDHA lactate dehydrogenase A 0.042543
B2M beta-2-microglobulin 0.0425074
RPL3 ribosomal protein L3 0.0420435
PKM pyruvate kinase, muscle 0.0420268
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0412969
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0407474
ENO2 enolase 2 (gamma, neuronal) 0.0405995
CENPF centromere protein F, 350/400kDa 0.0403902
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0394221
APLP2 amyloid beta (A4) precursor-like protein 2 0.039378
SMAD3 SMAD family member 3 0.0381537
COL5A1 collagen, type V, alpha 1 0.0376931
TPM3 tropomyosin 3 0.0370355
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0366531
MYH9 myosin, heavy chain 9, non-muscle 0.035837
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0356464
EEF2 eukaryotic translation elongation factor 2 0.0345785
PCBP2 poly(rC) binding protein 2 0.0343246
WWTR1 WW domain containing transcription regulator 1 0.034293
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0329626
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0325003
TXNIP thioredoxin interacting protein 0.0316786
MAP1B microtubule-associated protein 1B 0.0305232
YBX1 Y box binding protein 1 0.029881
ANKRD28 ankyrin repeat domain 28 0.0290089
FAM219A family with sequence similarity 219, member A 0.0284585
VEGFA vascular endothelial growth factor A 0.0275086
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.027415
ZNF638 zinc finger protein 638 0.0273385
ZBTB38 zinc finger and BTB domain containing 38 0.0273284
PTPRD protein tyrosine phosphatase, receptor type, D 0.0266613
AHNAK AHNAK nucleoprotein 0.026551
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.025854
ANLN anillin, actin binding protein 0.0255649
AXL AXL receptor tyrosine kinase 0.0255187
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.0254695
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0251027
MCL1 myeloid cell leukemia 1 0.0250858
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0250054
CKAP5 cytoskeleton associated protein 5 0.0249108
METTL15 methyltransferase like 15 0.024909
CALR calreticulin 0.0242916
SPRED1 sprouty-related, EVH1 domain containing 1 0.0238403
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0237353
NIBAN2 niban apoptosis regulator 2 0.0237001
HYOU1 hypoxia up-regulated 1 0.0236358
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0235718
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.0234959
SFPQ splicing factor proline/glutamine-rich 0.0234366
DGKD diacylglycerol kinase, delta 130kDa 0.0234081
MYO10 myosin X 0.0233782
FAT1 FAT atypical cadherin 1 0.0233658
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0233613
DNMBP dynamin binding protein 0.023273
TLN1 talin 1 0.0224235
LAMB1 laminin, beta 1 0.0221364
TNIP1 TNFAIP3 interacting protein 1 0.0220591
ANXA2 annexin A2 0.0216104
TIMP1 TIMP metallopeptidase inhibitor 1 0.0213701
IQGAP3 IQ motif containing GTPase activating protein 3 0.0212348
APP amyloid beta (A4) precursor protein 0.020639
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0202332
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.020207
EIF4B eukaryotic translation initiation factor 4B 0.020199
GRAMD1B GRAM domain containing 1B 0.0200723
PDIA6 protein disulfide isomerase family A, member 6 0.0199667
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.019819
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0194993
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0193809
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.019301
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0191087
SET SET nuclear proto-oncogene 0.0189618
FTH1 ferritin, heavy polypeptide 1 0.0187825
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0187664
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.0187438
FOSL1 FOS-like antigen 1 0.018284
CDC27 cell division cycle 27 0.0182124
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.0180687
VEGFC vascular endothelial growth factor C 0.0177897
DST dystonin 0.0177799
KIF4A kinesin family member 4A 0.0175669
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0173007
CHD1L chromodomain helicase DNA binding protein 1-like 0.0171578
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0171487
SEPTIN7 septin 7 0.0170795
GIGYF2 GRB10 interacting GYF protein 2 0.017065

decreased expression

Symbol Name Standardized Value
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.278748
NALF1 NALCN channel auxiliary factor 1 -0.16662
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.12854
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.108192
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.106778
TMSB10 thymosin beta 10 -0.0972914
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0882236
TPT1 tumor protein, translationally-controlled 1 -0.0758902
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0757489
EXT1 exostosin glycosyltransferase 1 -0.0728252
NDRG1 N-myc downstream regulated 1 -0.072498
VCL vinculin -0.0721423
PDE4D phosphodiesterase 4D, cAMP-specific -0.0654794
ASPH aspartate beta-hydroxylase -0.0649461
SDK1 sidekick cell adhesion molecule 1 -0.0645898
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.0642394
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0611582
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0601956
CALD1 caldesmon 1 -0.0547217
GARS1 glycyl-tRNA synthetase 1 -0.0543721
RPL35A ribosomal protein L35a -0.0510736
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0504437
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0501727
IGFBP5 insulin-like growth factor binding protein 5 -0.0496313
CADM1 cell adhesion molecule 1 -0.0495443
IGF2 insulin-like growth factor 2 -0.0487718
RPS24 ribosomal protein S24 -0.0476596
LMAN1 lectin, mannose-binding, 1 -0.0469058
STC1 stanniocalcin 1 -0.0466112
CDK13 cyclin-dependent kinase 13 -0.0441367
RAB1A RAB1A, member RAS oncogene family -0.0437433
FNDC3B fibronectin type III domain containing 3B -0.0434394
LPP LIM domain containing preferred translocation partner in lipoma -0.0430149
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0429059
WSB1 WD repeat and SOCS box containing 1 -0.0416681
EGFR epidermal growth factor receptor -0.0412756
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0408868
CANX calnexin -0.0403434
LRRC49 leucine rich repeat containing 49 -0.0397759
RPL34 ribosomal protein L34 -0.0396141
GRB10 growth factor receptor-bound protein 10 -0.0392961
CCND1 cyclin D1 -0.0389
TNNC1 troponin C type 1 (slow) -0.0382566
FTL ferritin, light polypeptide -0.0376606
GNAS GNAS complex locus -0.0365669
ZNF804A zinc finger protein 804A -0.0365391
TMEM263 transmembrane protein 263 -0.0360505
BACE2 beta-site APP-cleaving enzyme 2 -0.0355729
LOX lysyl oxidase -0.0355066
TPM4 tropomyosin 4 -0.0352015
HLA-B major histocompatibility complex, class I, B -0.0351443
ANTXR2 anthrax toxin receptor 2 -0.0346716
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0345522
HIP1 huntingtin interacting protein 1 -0.0345042
RRBP1 ribosome binding protein 1 -0.0344453
S100A6 S100 calcium binding protein A6 -0.0343463
IARS1 isoleucyl-tRNA synthetase 1 -0.0340026
SOX5 SRY (sex determining region Y)-box 5 -0.0331836
FNIP1 folliculin interacting protein 1 -0.0329213
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0325823
S100A10 S100 calcium binding protein A10 -0.0325171
FBXO11 F-box protein 11 -0.0323341
ZBTB20 zinc finger and BTB domain containing 20 -0.0323179
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0322674
AK1 adenylate kinase 1 -0.0322211
TRA2A transformer 2 alpha homolog (Drosophila) -0.0321679
TRIO trio Rho guanine nucleotide exchange factor -0.0308257
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 -0.0306393
INTS6 integrator complex subunit 6 -0.0303393
CAVIN1 caveolae associated protein 1 -0.0302242
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0288464
DTNA dystrobrevin, alpha -0.0286712
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0285154
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0282737
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0281935
VIM vimentin -0.0280873
RPS6 ribosomal protein S6 -0.0280816
RTN4 reticulon 4 -0.0278944
HLA-C major histocompatibility complex, class I, C -0.0278822
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0278557
RAB7A RAB7A, member RAS oncogene family -0.0277777
RPL19 ribosomal protein L19 -0.0276415
RAB2A RAB2A, member RAS oncogene family -0.0275125
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0273753
TTC3 tetratricopeptide repeat domain 3 -0.0271782
GOLGB1 golgin B1 -0.0270295
TPTE transmembrane phosphatase with tensin homology -0.0269316
MYSM1 Myb-like, SWIRM and MPN domains 1 -0.0267859
TMED3 transmembrane emp24 protein transport domain containing 3 -0.0267476
GPR173 G protein-coupled receptor 173 -0.0265848
MAP4 microtubule-associated protein 4 -0.0264022
IGFBP3 insulin-like growth factor binding protein 3 -0.0261705
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -0.0261576
IER3 immediate early response 3 -0.0261525
CREB5 cAMP responsive element binding protein 5 -0.0259643
PTMA prothymosin, alpha -0.0258904
HM13 histocompatibility (minor) 13 -0.0258678
SEC31A SEC31 homolog A (S. cerevisiae) -0.0258643
BBS9 Bardet-Biedl syndrome 9 -0.0258414
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0257131