Gallic acid_HEC-1-A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in HEC-1-A cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MYH9 myosin, heavy chain 9, non-muscle 0.186964
ACTG1 actin gamma 1 0.137868
ENO1 enolase 1, (alpha) 0.134076
POTEF POTE ankyrin domain family, member F 0.125819
AHNAK AHNAK nucleoprotein 0.109725
APP amyloid beta (A4) precursor protein 0.0939812
EEF2 eukaryotic translation elongation factor 2 0.0820289
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0810989
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0794162
RPL3 ribosomal protein L3 0.0775184
PRELID2 PRELI domain containing 2 0.0751233
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0723449
SET SET nuclear proto-oncogene 0.0694396
MACROD2 MACRO domain containing 2 0.0638913
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0633301
PCBP2 poly(rC) binding protein 2 0.0628154
ASPH aspartate beta-hydroxylase 0.061703
FLNA filamin A, alpha 0.0567194
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0535756
HSPA8 heat shock 70kDa protein 8 0.0533866
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0533757
PLEC plectin 0.0513889
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0501197
TPM3 tropomyosin 3 0.0468267
DIAPH1 diaphanous-related formin 1 0.046359
EIF4B eukaryotic translation initiation factor 4B 0.0455921
RPL4 ribosomal protein L4 0.0448662
MYEOV myeloma overexpressed 0.0435664
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0412664
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0402177
PKM pyruvate kinase, muscle 0.0399563
APLP2 amyloid beta (A4) precursor-like protein 2 0.0398512
AXL AXL receptor tyrosine kinase 0.038563
RPS2 ribosomal protein S2 0.0382015
DSPP dentin sialophosphoprotein 0.0381573
CALR calreticulin 0.0381244
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0378402
YBX1 Y box binding protein 1 0.0376838
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0376168
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0373724
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0370936
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0369538
SFPQ splicing factor proline/glutamine-rich 0.0366693
OSBPL10 oxysterol binding protein-like 10 0.0362643
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0358754
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0352175
BBS9 Bardet-Biedl syndrome 9 0.0351844
NRIP1 nuclear receptor interacting protein 1 0.0342773
KDM6A lysine (K)-specific demethylase 6A 0.0342548
SMC1A structural maintenance of chromosomes 1A 0.0341174
USP9X ubiquitin specific peptidase 9, X-linked 0.0339011
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0333906
P4HB prolyl 4-hydroxylase, beta polypeptide 0.03323
ZNF148 zinc finger protein 148 0.0330575
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0329032
SRRM2 serine/arginine repetitive matrix 2 0.0326538
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0322312
SMAD3 SMAD family member 3 0.032231
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.0305447
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0305425
RPS12 ribosomal protein S12 0.0304045
MPRIP myosin phosphatase Rho interacting protein 0.0301283
LDHA lactate dehydrogenase A 0.0299082
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0297697
NFE2L1 nuclear factor, erythroid 2-like 1 0.0296028
ANKRD36 ankyrin repeat domain 36 0.0295616
FTH1 ferritin, heavy polypeptide 1 0.0288374
YAP1 Yes-associated protein 1 0.0286807
CSDE1 cold shock domain containing E1, RNA-binding 0.0284629
WDFY3 WD repeat and FYVE domain containing 3 0.0284493
ATAD2 ATPase family, AAA domain containing 2 0.0283505
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0281721
MACF1 microtubule-actin crosslinking factor 1 0.0281398
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.0280564
SNX9 sorting nexin 9 0.0278913
EIF4H eukaryotic translation initiation factor 4H 0.0277616
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0273365
PICALM phosphatidylinositol binding clathrin assembly protein 0.0272336
FAT1 FAT atypical cadherin 1 0.0268592
AFDN afadin, adherens junction formation factor 0.0263863
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0262939
RAD23B RAD23 homolog B (S. cerevisiae) 0.0262437
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.0261284
TOP2B topoisomerase (DNA) II beta 180kDa 0.0260772
PLS3 plastin 3 0.025932
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0258873
PTEN phosphatase and tensin homolog 0.0258406
SRSF4 serine/arginine-rich splicing factor 4 0.0257521
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.0254326
PARD3B par-3 family cell polarity regulator beta 0.0254324
OGA O-GlcNAcase 0.0252117
HLTF helicase-like transcription factor 0.0251479
WAC WW domain containing adaptor with coiled-coil 0.0243014
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0241978
ADAM9 ADAM metallopeptidase domain 9 0.0241847
GSK3B glycogen synthase kinase 3 beta 0.0239057
WWOX WW domain containing oxidoreductase 0.0238307
CLTC clathrin, heavy chain (Hc) 0.0236737
PDIA6 protein disulfide isomerase family A, member 6 0.0234695
RBBP7 retinoblastoma binding protein 7 0.0233506

decreased expression

Symbol Name Standardized Value
TMSB10 thymosin beta 10 -0.122305
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.114917
IGFBP3 insulin-like growth factor binding protein 3 -0.114044
TPT1 tumor protein, translationally-controlled 1 -0.113051
ALCAM activated leukocyte cell adhesion molecule -0.0879611
CCND1 cyclin D1 -0.0874758
HMGA1 high mobility group AT-hook 1 -0.0794489
NDRG1 N-myc downstream regulated 1 -0.0758911
RPL35A ribosomal protein L35a -0.0731349
DLC1 DLC1 Rho GTPase activating protein -0.0668434
RHEX regulator of hemoglobinization and erythroid cell expansion -0.0593309
RPS6 ribosomal protein S6 -0.0587565
ITGB8 integrin, beta 8 -0.0581574
MT2A metallothionein 2A -0.0578224
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0557975
FTL ferritin, light polypeptide -0.0545841
S100A10 S100 calcium binding protein A10 -0.0535141
HMGA2 high mobility group AT-hook 2 -0.0505502
RPL34 ribosomal protein L34 -0.0492392
RPS24 ribosomal protein S24 -0.0488538
PTMA prothymosin, alpha -0.0475409
CREB5 cAMP responsive element binding protein 5 -0.0450151
VDAC1 voltage-dependent anion channel 1 -0.0445227
GNAS GNAS complex locus -0.0435103
LIMCH1 LIM and calponin homology domains 1 -0.0433121
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0426268
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0409967
RPL32 ribosomal protein L32 -0.0403245
EMP1 epithelial membrane protein 1 -0.040292
HMGB1 high mobility group box 1 -0.0401796
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0391219
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0390104
IER3 immediate early response 3 -0.038336
H1-0 H1.0 linker histone -0.0380534
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0374204
EGFR epidermal growth factor receptor -0.037215
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0354787
MAML2 mastermind-like 2 (Drosophila) -0.0348885
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0347614
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0346231
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -0.0343028
EGR1 early growth response 1 -0.0326633
BICD1 bicaudal D homolog 1 (Drosophila) -0.032403
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.0315251
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0312612
F3 coagulation factor III (thromboplastin, tissue factor) -0.031215
WDR45B WD repeat domain 45B -0.0312088
PAX8 paired box 8 -0.0310825
LMNA lamin A/C -0.0310421
RPS11 ribosomal protein S11 -0.0304622
RPL8 ribosomal protein L8 -0.0302038
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0299103
PTPRK protein tyrosine phosphatase, receptor type, K -0.029802
CLDN1 claudin 1 -0.029708
ANKRD10 ankyrin repeat domain 10 -0.0296853
CD44 CD44 molecule (Indian blood group) -0.0295538
FRAS1 Fraser extracellular matrix complex subunit 1 -0.0286591
RPL31 ribosomal protein L31 -0.0286194
DSCAML1 Down syndrome cell adhesion molecule like 1 -0.0281691
WWC1 WW and C2 domain containing 1 -0.0279949
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0275398
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0274985
KRT19 keratin 19, type I -0.0273617
S100A6 S100 calcium binding protein A6 -0.0272157
SBF2 SET binding factor 2 -0.0269375
PCED1B PC-esterase domain containing 1B -0.0264325
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0262005
ARHGAP26 Rho GTPase activating protein 26 -0.0261962
MAP4 microtubule-associated protein 4 -0.0261062
LITAF lipopolysaccharide-induced TNF factor -0.0258987
ATG7 autophagy related 7 -0.0257014
RSL1D1 ribosomal L1 domain containing 1 -0.0256668
FUS FUS RNA binding protein -0.0256029
MYO1E myosin IE -0.0254106
SCLT1 sodium channel and clathrin linker 1 -0.0253917
FBXL2 F-box and leucine-rich repeat protein 2 -0.0251964
KRT7 keratin 7, type II -0.0250329
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.024604
WSB1 WD repeat and SOCS box containing 1 -0.0245224
LMAN1 lectin, mannose-binding, 1 -0.0245121
DOCK4 dedicator of cytokinesis 4 -0.0244411
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0242445
RPS29 ribosomal protein S29 -0.0242324
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -0.0241684
ANXA2 annexin A2 -0.0239863
S100A9 S100 calcium binding protein A9 -0.023937
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 -0.0239125
LAMA4 laminin, alpha 4 -0.0238457
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -0.0238254
KDM3A lysine (K)-specific demethylase 3A -0.023654
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0234128
SSH2 slingshot protein phosphatase 2 -0.0232267
RPL38 ribosomal protein L38 -0.0232193
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.0231756
RPS14 ribosomal protein S14 -0.0231663
S100A4 S100 calcium binding protein A4 -0.0228525
RPL28 ribosomal protein L28 -0.0227799
ARF1 ADP-ribosylation factor 1 -0.0227565
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0227363
RAB7A RAB7A, member RAS oncogene family -0.0227043