Gallic acid_HOP62 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in HOP62 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.172651
ENO1 enolase 1, (alpha) 0.162958
COL5A1 collagen, type V, alpha 1 0.154449
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.143745
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.131494
CD44 CD44 molecule (Indian blood group) 0.129237
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.120554
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.117996
COL6A3 collagen, type VI, alpha 3 0.116427
MYH9 myosin, heavy chain 9, non-muscle 0.108473
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.101545
NAV1 neuron navigator 1 0.0886787
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0875858
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0834007
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0804302
AKAP12 A kinase (PRKA) anchor protein 12 0.0785285
ACTG1 actin gamma 1 0.0768381
ERRFI1 ERBB receptor feedback inhibitor 1 0.0764256
PLEC plectin 0.0750811
MT2A metallothionein 2A 0.072593
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0689383
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0686679
MYO10 myosin X 0.0677522
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0644547
HMGA2 high mobility group AT-hook 2 0.0600392
MPRIP myosin phosphatase Rho interacting protein 0.0571395
SEPTIN9 septin 9 0.0541647
TRIO trio Rho guanine nucleotide exchange factor 0.0539891
ASPH aspartate beta-hydroxylase 0.0524252
DNMBP dynamin binding protein 0.0520537
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.051142
RFX8 RFX family member 8, lacking RFX DNA binding domain 0.0500519
DST dystonin 0.0498928
AXL AXL receptor tyrosine kinase 0.0493432
EEF2 eukaryotic translation elongation factor 2 0.0480804
TIMP1 TIMP metallopeptidase inhibitor 1 0.0457963
HSPA8 heat shock 70kDa protein 8 0.0453268
WWOX WW domain containing oxidoreductase 0.0451371
VEGFA vascular endothelial growth factor A 0.0440287
RRM2 ribonucleotide reductase M2 0.043792
BICD1 bicaudal D homolog 1 (Drosophila) 0.0435379
ANXA2 annexin A2 0.042198
SMAD3 SMAD family member 3 0.0418293
MCL1 myeloid cell leukemia 1 0.0416903
LAMB3 laminin, beta 3 0.0415073
EFNA5 ephrin-A5 0.0408995
ZBTB38 zinc finger and BTB domain containing 38 0.040286
NIBAN2 niban apoptosis regulator 2 0.0400586
MAP1B microtubule-associated protein 1B 0.0399895
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.039875
GRAMD1B GRAM domain containing 1B 0.0392585
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0391947
MLPH melanophilin 0.0383888
TPM3 tropomyosin 3 0.0383642
PRSS23 protease, serine, 23 0.0379187
RPL3 ribosomal protein L3 0.0376431
NALF1 NALCN channel auxiliary factor 1 0.0367441
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 0.0362909
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0359116
DOCK5 dedicator of cytokinesis 5 0.0357455
PTPRM protein tyrosine phosphatase, receptor type, M 0.03565
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0348916
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0346209
LDHA lactate dehydrogenase A 0.0344695
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0334828
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0333405
APP amyloid beta (A4) precursor protein 0.03289
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0327914
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0322464
ANGPTL4 angiopoietin-like 4 0.0321238
MSN moesin 0.0308788
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0308202
PCBP2 poly(rC) binding protein 2 0.0308178
POTEF POTE ankyrin domain family, member F 0.0306263
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0306048
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0305593
ACTN4 actinin, alpha 4 0.0303505
RPL23 ribosomal protein L23 0.0301627
GPC5 glypican 5 0.0298863
CAPRIN2 caprin family member 2 0.029727
PODXL podocalyxin-like 0.0294871
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0293228
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0293175
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0293055
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0291188
JAG1 jagged 1 0.0290927
ARHGAP22 Rho GTPase activating protein 22 0.0290557
RPS3 ribosomal protein S3 0.0289291
WWTR1 WW domain containing transcription regulator 1 0.0288928
MACF1 microtubule-actin crosslinking factor 1 0.0287482
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0287067
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.028523
KIAA1549L KIAA1549-like 0.027964
RPS12 ribosomal protein S12 0.0278164
VEGFC vascular endothelial growth factor C 0.0275097
ANKRD11 ankyrin repeat domain 11 0.0274608
CALR calreticulin 0.0271459
NFE2L1 nuclear factor, erythroid 2-like 1 0.0271412
FAT1 FAT atypical cadherin 1 0.0269635
RPL4 ribosomal protein L4 0.0262744

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.270871
IGF2 insulin-like growth factor 2 -0.127703
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.113316
FN1 fibronectin 1 -0.105052
CDH13 cadherin 13 -0.10425
CXCL8 chemokine (C-X-C motif) ligand 8 -0.101423
EGR1 early growth response 1 -0.088494
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0866465
NDRG1 N-myc downstream regulated 1 -0.0786275
VIM vimentin -0.0733025
ELL2 elongation factor, RNA polymerase II, 2 -0.0713848
FNDC3B fibronectin type III domain containing 3B -0.0621382
SPAG9 sperm associated antigen 9 -0.0542859
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0528583
TMSB10 thymosin beta 10 -0.0481015
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0478344
MORF4L2 mortality factor 4 like 2 -0.047217
RRBP1 ribosome binding protein 1 -0.0457089
CD109 CD109 molecule -0.044898
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0448203
LCORL ligand dependent nuclear receptor corepressor-like -0.0446004
SEC31A SEC31 homolog A (S. cerevisiae) -0.044501
IER3 immediate early response 3 -0.0433509
NGLY1 N-glycanase 1 -0.0423609
SETD5 SET domain containing 5 -0.0420124
STC1 stanniocalcin 1 -0.0414579
TGFBI transforming growth factor, beta-induced, 68kDa -0.0414035
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0407402
GOLGA4 golgin A4 -0.0406687
WSB1 WD repeat and SOCS box containing 1 -0.0406535
CCND1 cyclin D1 -0.0405189
HDLBP high density lipoprotein binding protein -0.0393752
SIPA1L3 signal-induced proliferation-associated 1 like 3 -0.0391825
NF1 neurofibromin 1 -0.0387706
SBF2 SET binding factor 2 -0.0387082
RAB1A RAB1A, member RAS oncogene family -0.0381733
TMEM263 transmembrane protein 263 -0.0371725
RNMT RNA (guanine-7-) methyltransferase -0.0370899
WDR45B WD repeat domain 45B -0.0364173
SEC24A SEC24 family member A -0.0354839
CANX calnexin -0.0351512
FAM13A family with sequence similarity 13, member A -0.0341815
NAMPT nicotinamide phosphoribosyltransferase -0.0341582
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0340416
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0338888
FMN1 formin 1 -0.0330156
KDM3A lysine (K)-specific demethylase 3A -0.0326943
IGFBP4 insulin-like growth factor binding protein 4 -0.0317245
PDE10A phosphodiesterase 10A -0.0314307
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0312086
GNAS GNAS complex locus -0.0311727
APOLD1 apolipoprotein L domain containing 1 -0.0310767
BTG1 B-cell translocation gene 1, anti-proliferative -0.0309362
BIRC6 baculoviral IAP repeat containing 6 -0.0304663
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0304659
RTN4 reticulon 4 -0.0303706
LOX lysyl oxidase -0.0302957
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0301074
LMAN1 lectin, mannose-binding, 1 -0.0294507
PTMA prothymosin, alpha -0.029392
SEC24D SEC24 family member D -0.0293816
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.029037
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.028705
TAS2R14 taste receptor, type 2, member 14 -0.028664
WASF2 WAS protein family, member 2 -0.0278938
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0276349
ADM adrenomedullin -0.0273039
INHBA inhibin, beta A -0.0271953
RBM39 RNA binding motif protein 39 -0.0271602
RAP1B RAP1B, member of RAS oncogene family -0.0271544
FNIP1 folliculin interacting protein 1 -0.0271149
COPB1 coatomer protein complex, subunit beta 1 -0.0269719
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0263212
IL1B interleukin 1, beta -0.0262669
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.0262241
ZFAND3 zinc finger, AN1-type domain 3 -0.0261882
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0259266
TTC3 tetratricopeptide repeat domain 3 -0.0257996
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0256379
RLF rearranged L-myc fusion -0.0256298
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0254978
MIMS1 mitochondrial inner membrane scaffold 1 -0.0251343
CALU calumenin -0.0250862
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0250038
USP3 ubiquitin specific peptidase 3 -0.0250029
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0249117
KDM5B lysine (K)-specific demethylase 5B -0.0247993
NABP1 nucleic acid binding protein 1 -0.024426
VCL vinculin -0.0242132
TPX2 TPX2, microtubule-associated -0.0241879
MIS18BP1 MIS18 binding protein 1 -0.0241422
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0239761
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.023877
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0238646
SDK1 sidekick cell adhesion molecule 1 -0.0235738
GOLT1B golgi transport 1B -0.0234622
RAB2A RAB2A, member RAS oncogene family -0.0232971
SRP54 signal recognition particle 54kDa -0.0230743
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.0229745
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0228345