| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Gallic acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Gallic acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.40059 |
| ENO1 | enolase 1, (alpha) | 0.15801 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.147944 |
| VEGFA | vascular endothelial growth factor A | 0.137647 |
| MT2A | metallothionein 2A | 0.135007 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.122493 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.117866 |
| COL5A1 | collagen, type V, alpha 1 | 0.106923 |
| AHNAK | AHNAK nucleoprotein | 0.0954953 |
| NDRG1 | N-myc downstream regulated 1 | 0.0861108 |
| CALR | calreticulin | 0.0858964 |
| CDH13 | cadherin 13 | 0.0823388 |
| ASPH | aspartate beta-hydroxylase | 0.0794486 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0789785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0709634 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0621144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0611539 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0600484 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0569387 |
| APP | amyloid beta (A4) precursor protein | 0.0567302 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0565865 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0554007 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0504316 |
| PLEC | plectin | 0.0490749 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0489026 |
| RUNX1 | runt-related transcription factor 1 | 0.0477268 |
| LOXL2 | lysyl oxidase-like 2 | 0.0461146 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0459459 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0452309 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0443067 |
| POTEF | POTE ankyrin domain family, member F | 0.0442584 |
| RPL3 | ribosomal protein L3 | 0.0430013 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0417685 |
| MYO10 | myosin X | 0.0405851 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0402972 |
| NAV1 | neuron navigator 1 | 0.0399086 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0387349 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.037948 |
| EGFR | epidermal growth factor receptor | 0.037721 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0373226 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0371855 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0366685 |
| NOTCH2 | notch 2 | 0.0365328 |
| EFNA5 | ephrin-A5 | 0.0362575 |
| ACTG1 | actin gamma 1 | 0.0359503 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0347413 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0346522 |
| HYOU1 | hypoxia up-regulated 1 | 0.0342304 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0333068 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0331492 |
| RPS12 | ribosomal protein S12 | 0.0326387 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0313658 |
| NAV2 | neuron navigator 2 | 0.0308565 |
| HAS2 | hyaluronan synthase 2 | 0.0306929 |
| FAT1 | FAT atypical cadherin 1 | 0.0304452 |
| RPS3 | ribosomal protein S3 | 0.0302106 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0300459 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0299168 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0296924 |
| DST | dystonin | 0.029173 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0291657 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0290622 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0283656 |
| MCL1 | myeloid cell leukemia 1 | 0.0277909 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0274405 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0271218 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0270843 |
| TNS1 | tensin 1 | 0.0261114 |
| RPL37A | ribosomal protein L37a | 0.0261 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260645 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0260359 |
| PTK2 | protein tyrosine kinase 2 | 0.0258776 |
| FMNL2 | formin-like 2 | 0.025847 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0256261 |
| PCBP2 | poly(rC) binding protein 2 | 0.0255668 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0254026 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0251574 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0246513 |
| FAM219A | family with sequence similarity 219, member A | 0.0245822 |
| TPM3 | tropomyosin 3 | 0.0244558 |
| SMYD3 | SET and MYND domain containing 3 | 0.0241387 |
| RPL23 | ribosomal protein L23 | 0.0240014 |
| B2M | beta-2-microglobulin | 0.0239779 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0231917 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0229839 |
| TLN1 | talin 1 | 0.0229652 |
| ANGPTL4 | angiopoietin-like 4 | 0.0229198 |
| MSN | moesin | 0.0228129 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0227758 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0224249 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0223813 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0223411 |
| DSPP | dentin sialophosphoprotein | 0.022175 |
| SETBP1 | SET binding protein 1 | 0.0220515 |
| ANXA1 | annexin A1 | 0.0218423 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.021409 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.021177 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0211513 |
| YBX1 | Y box binding protein 1 | 0.0210067 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.020969 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.216623 |
| COL1A1 | collagen, type I, alpha 1 | -0.215362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158785 |
| VIM | vimentin | -0.124796 |
| FN1 | fibronectin 1 | -0.112741 |
| IER3 | immediate early response 3 | -0.0916527 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0877662 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.083182 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0740768 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0674788 |
| PALLD | palladin, cytoskeletal associated protein | -0.0665691 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0599746 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0581771 |
| CALD1 | caldesmon 1 | -0.0567091 |
| VCL | vinculin | -0.0549926 |
| SPAG9 | sperm associated antigen 9 | -0.0506413 |
| CLIC4 | chloride intracellular channel 4 | -0.0499835 |
| EGR1 | early growth response 1 | -0.0481695 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0475648 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0460648 |
| CD44 | CD44 molecule (Indian blood group) | -0.0460428 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0425287 |
| STC1 | stanniocalcin 1 | -0.0421753 |
| RRBP1 | ribosome binding protein 1 | -0.0419256 |
| TMSB10 | thymosin beta 10 | -0.0407696 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0385336 |
| POSTN | periostin, osteoblast specific factor | -0.0383609 |
| OSMR | oncostatin M receptor | -0.0380882 |
| LOX | lysyl oxidase | -0.0378213 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0377592 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0369582 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.036695 |
| MAP1B | microtubule-associated protein 1B | -0.0354076 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0348664 |
| COL1A2 | collagen, type I, alpha 2 | -0.0342643 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0327555 |
| SQLE | squalene epoxidase | -0.0325959 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0313381 |
| THY1 | Thy-1 cell surface antigen | -0.0310157 |
| RIGI | RNA sensor RIG-I | -0.0309117 |
| TMEM263 | transmembrane protein 263 | -0.030502 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0301764 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0287874 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0285942 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0282511 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0281323 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0280638 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0276756 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0274506 |
| H1-0 | H1.0 linker histone | -0.0273575 |
| NREP | neuronal regeneration related protein | -0.0273532 |
| IL6ST | interleukin 6 signal transducer | -0.0270871 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0270862 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0267216 |
| UBC | ubiquitin C | -0.0264958 |
| PXDN | peroxidasin | -0.0264351 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0260259 |
| WASF2 | WAS protein family, member 2 | -0.0258945 |
| TRAM1 | translocation associated membrane protein 1 | -0.0258599 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0258401 |
| SBF2 | SET binding factor 2 | -0.0257152 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0257142 |
| TAPBP | TAP binding protein (tapasin) | -0.0257059 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0254178 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0252517 |
| INHBA | inhibin, beta A | -0.0251865 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0249173 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0246812 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0245127 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.024458 |
| EBF1 | early B-cell factor 1 | -0.0244455 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.024261 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.023875 |
| TFG | TRK-fused gene | -0.023795 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0236098 |
| JAK2 | Janus kinase 2 | -0.0235725 |
| HMGA1 | high mobility group AT-hook 1 | -0.0233253 |
| TMEM39A | transmembrane protein 39A | -0.0231668 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0226742 |
| ARF1 | ADP-ribosylation factor 1 | -0.0225636 |
| SRGN | serglycin | -0.0224717 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0222687 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0222518 |
| TUBB | tubulin, beta class I | -0.0220967 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0220951 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0217993 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0217725 |
| TMEM123 | transmembrane protein 123 | -0.0216777 |
| GOLT1B | golgi transport 1B | -0.0215482 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0213656 |
| HDLBP | high density lipoprotein binding protein | -0.0212888 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0211979 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0211453 |
| CNTN5 | contactin 5 | -0.0210894 |
| MORF4L2 | mortality factor 4 like 2 | -0.0210184 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0208994 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0208143 |
| RHEB | Ras homolog enriched in brain | -0.0208045 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0204149 |
| RASA2 | RAS p21 protein activator 2 | -0.0202197 |