Gallic acid_HT-29 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in HT-29 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LMO7 LIM domain 7 0.078866
AHNAK AHNAK nucleoprotein 0.0767757
FAT1 FAT atypical cadherin 1 0.0478558
BCL2L1 BCL2-like 1 0.0449369
STK24 serine/threonine kinase 24 0.0401909
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0398417
ANXA11 annexin A11 0.0331562
MYH9 myosin, heavy chain 9, non-muscle 0.0316077
WWC1 WW and C2 domain containing 1 0.0301293
POTEF POTE ankyrin domain family, member F 0.028541
ARHGAP23 Rho GTPase activating protein 23 0.0274147
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.026046
NIBAN2 niban apoptosis regulator 2 0.0254755
FTH1 ferritin, heavy polypeptide 1 0.024182
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.023744
RHPN2 rhophilin, Rho GTPase binding protein 2 0.0234315
CLIC5 chloride intracellular channel 5 0.0224949
TJP2 tight junction protein 2 0.0223178
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0211862
RPL3 ribosomal protein L3 0.020421
TGFA transforming growth factor, alpha 0.0200753
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0198415
SEPTIN9 septin 9 0.0195854
ARHGAP42 Rho GTPase activating protein 42 0.0194418
PLK2 polo-like kinase 2 0.0193888
PLEC plectin 0.0189133
NTN4 netrin 4 0.0187656
PPL periplakin 0.0187218
KIAA0232 KIAA0232 0.018476
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.0180388
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.0175379
UTRN utrophin 0.0169932
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0168619
DSPP dentin sialophosphoprotein 0.0165053
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.0162564
FOXO1 forkhead box O1 0.0153631
ITGB4 integrin, beta 4 0.0151804
MSN moesin 0.0151255
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0143732
EPS8L1 EPS8-like 1 0.0142584
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.0140991
CLMN calmin (calponin-like, transmembrane) 0.0140794
PRSS22 protease, serine, 22 0.0140324
BCL9L B-cell CLL/lymphoma 9-like 0.0140306
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.0137934
C1D C1D nuclear receptor corepressor 0.0137837
TMEM45B transmembrane protein 45B 0.0136024
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0134288
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0134152
FLNB filamin B, beta 0.0133358
AGRN agrin 0.0131428
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0131352
PDZD8 PDZ domain containing 8 0.0128843
PPARG peroxisome proliferator-activated receptor gamma 0.0128719
TNS3 tensin 3 0.0128508
TNS4 tensin 4 0.0128334
CAB39 calcium binding protein 39 0.0125005
MYO5B myosin VB 0.0124831
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0124788
SPRED2 sprouty-related, EVH1 domain containing 2 0.0122993
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.0121735
NFE2L1 nuclear factor, erythroid 2-like 1 0.0121613
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.0121354
MYEOV myeloma overexpressed 0.0120293
YPEL2 yippee-like 2 (Drosophila) 0.0119112
DNM2 dynamin 2 0.0117551
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.011737
EIF4B eukaryotic translation initiation factor 4B 0.0115348
GSE1 Gse1 coiled-coil protein 0.0113644
SMAD3 SMAD family member 3 0.0109425
ITPRID2 ITPR interacting domain containing 2 0.0108781
RNF43 ring finger protein 43 0.01085
NCOR2 nuclear receptor corepressor 2 0.0108179
CTTNBP2NL CTTNBP2 N-terminal like 0.0107197
CLMB calcimembrin 0.0106717
LATS2 large tumor suppressor kinase 2 0.0106213
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0106079
CNOT12 CCR4-NOT transcription complex subunit 12 0.0105539
MYOF myoferlin 0.0104601
YAP1 Yes-associated protein 1 0.0104012
TACC2 transforming, acidic coiled-coil containing protein 2 0.0102026
DST dystonin 0.0102017
LRMDA leucine rich melanocyte differentiation associated 0.0101469
NPEPPS aminopeptidase puromycin sensitive 0.0101456
AXIN2 axin 2 0.00976646
MINK1 misshapen-like kinase 1 0.00974916
SPRED1 sprouty-related, EVH1 domain containing 1 0.00974555
MAT2A methionine adenosyltransferase II, alpha 0.00943893
TRAPPC9 trafficking protein particle complex 9 0.00940246
PLXNB2 plexin B2 0.00925688
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0092368
EPHA2 EPH receptor A2 0.00922944
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.00907445
MAN1A1 mannosidase, alpha, class 1A, member 1 0.00904461
CEMIP cell migration inducing protein, hyaluronan binding 0.00892386
DIAPH1 diaphanous-related formin 1 0.00880007
ATP9A ATPase, class II, type 9A 0.00876944
IFFO2 intermediate filament family orphan 2 0.00869836
TNRC18 trinucleotide repeat containing 18 0.00866879
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 0.00857603

decreased expression

Symbol Name Standardized Value
TPT1 tumor protein, translationally-controlled 1 -0.184765
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.161934
PTMA prothymosin, alpha -0.148814
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.122064
NDRG1 N-myc downstream regulated 1 -0.119397
MYH14 myosin, heavy chain 14, non-muscle -0.0973798
RPS6 ribosomal protein S6 -0.0960465
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0939891
TMSB10 thymosin beta 10 -0.0884573
PDIA3 protein disulfide isomerase family A, member 3 -0.0848695
GMDS GDP-mannose 4,6-dehydratase -0.0739725
FTL ferritin, light polypeptide -0.0718945
RPS27A ribosomal protein S27a -0.070321
EXT1 exostosin glycosyltransferase 1 -0.069584
FRY furry homolog (Drosophila) -0.0684478
RAD21 RAD21 homolog (S. pombe) -0.0677095
RPLP1 ribosomal protein, large, P1 -0.0643902
RPS24 ribosomal protein S24 -0.0637905
RPS8 ribosomal protein S8 -0.063551
UBC ubiquitin C -0.062812
INTS6 integrator complex subunit 6 -0.06232
RPL23 ribosomal protein L23 -0.0615342
KRT20 keratin 20, type I -0.0609711
GARS1 glycyl-tRNA synthetase 1 -0.0609242
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0569383
SQSTM1 sequestosome 1 -0.0562779
CANX calnexin -0.0557504
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0542484
AGR2 anterior gradient 2 -0.0540175
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0539537
GOLGA4 golgin A4 -0.0539418
PDIA4 protein disulfide isomerase family A, member 4 -0.0530508
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0521499
FNDC3B fibronectin type III domain containing 3B -0.0519672
RPL34 ribosomal protein L34 -0.0513195
LAMA4 laminin, alpha 4 -0.0512196
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0504912
RPS19 ribosomal protein S19 -0.0501418
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0499871
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -0.0489634
RPLP2 ribosomal protein, large, P2 -0.0488219
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0486925
RPS3 ribosomal protein S3 -0.0479197
JUN jun proto-oncogene -0.0474163
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0474069
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0461429
ACTN4 actinin, alpha 4 -0.0455692
EGR1 early growth response 1 -0.0454252
RPL35A ribosomal protein L35a -0.0451124
GNAS GNAS complex locus -0.0449632
RPS13 ribosomal protein S13 -0.0443237
RPS25 ribosomal protein S25 -0.0438624
KDM3A lysine (K)-specific demethylase 3A -0.0437958
RPL9 ribosomal protein L9 -0.0429002
RPS11 ribosomal protein S11 -0.0426513
RPS16 ribosomal protein S16 -0.0425844
ANXA2 annexin A2 -0.0424456
EIF1 eukaryotic translation initiation factor 1 -0.0423904
S100A6 S100 calcium binding protein A6 -0.0423278
NF1 neurofibromin 1 -0.0422883
RTN3 reticulon 3 -0.0422867
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0421866
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.0421396
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0420205
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0418188
RAB7A RAB7A, member RAS oncogene family -0.0414559
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0412722
RPL12 ribosomal protein L12 -0.0409058
RPLP0 ribosomal protein, large, P0 -0.0407602
DIAPH2 diaphanous-related formin 2 -0.0405207
RPS5 ribosomal protein S5 -0.0404931
HM13 histocompatibility (minor) 13 -0.0404761
LYZ lysozyme -0.0400153
RBM39 RNA binding motif protein 39 -0.0399071
ERN1 endoplasmic reticulum to nucleus signaling 1 -0.0397642
RPL27A ribosomal protein L27a -0.039354
ADARB1 adenosine deaminase, RNA-specific, B1 -0.0392297
TOP1 topoisomerase (DNA) I -0.0390824
PTPRK protein tyrosine phosphatase, receptor type, K -0.0386557
CCSER1 coiled-coil serine-rich protein 1 -0.0381844
AREG amphiregulin -0.0380068
ANKRD12 ankyrin repeat domain 12 -0.0379679
TJP1 tight junction protein 1 -0.0379644
IARS1 isoleucyl-tRNA synthetase 1 -0.0379175
RPS12 ribosomal protein S12 -0.0376547
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.037209
SEC31A SEC31 homolog A (S. cerevisiae) -0.0371512
TES testin LIM domain protein -0.0365254
RAB1A RAB1A, member RAS oncogene family -0.0361295
TMEM65 transmembrane protein 65 -0.0360199
PTK2 protein tyrosine kinase 2 -0.035888
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -0.0357384
CD2AP CD2-associated protein -0.0357285
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0353581
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0353215
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0352869
S100A10 S100 calcium binding protein A10 -0.035286
RPL28 ribosomal protein L28 -0.035231
SLC38A2 solute carrier family 38, member 2 -0.0351363
ATXN1 ataxin 1 -0.03495