Gallic acid_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.203639
ENO1 enolase 1, (alpha) 0.132191
MYOF myoferlin 0.128575
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0788014
FN1 fibronectin 1 0.0786472
PLEC plectin 0.0661145
AOPEP aminopeptidase O (putative) 0.0580158
CEMIP cell migration inducing protein, hyaluronan binding 0.056766
MYH9 myosin, heavy chain 9, non-muscle 0.055227
CD44 CD44 molecule (Indian blood group) 0.0529252
BZW1 basic leucine zipper and W2 domains 1 0.0528939
TPM3 tropomyosin 3 0.0501936
TGM2 transglutaminase 2 0.0500937
DOK5 docking protein 5 0.0497514
LMO7 LIM domain 7 0.0491923
MSN moesin 0.0481718
MCL1 myeloid cell leukemia 1 0.0479144
EEF2 eukaryotic translation elongation factor 2 0.047774
PALM2AKAP2 PALM2 and AKAP2 fusion 0.047298
MACF1 microtubule-actin crosslinking factor 1 0.0467526
SMAD3 SMAD family member 3 0.0456596
EHBP1L1 EH domain binding protein 1-like 1 0.0448547
HSPA8 heat shock 70kDa protein 8 0.044649
FOXP1 forkhead box P1 0.0440143
LDHA lactate dehydrogenase A 0.0412514
PGK1 phosphoglycerate kinase 1 0.0407745
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.040695
APP amyloid beta (A4) precursor protein 0.0402912
TXNIP thioredoxin interacting protein 0.0400183
LAMC2 laminin, gamma 2 0.0398285
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0396455
RPL3 ribosomal protein L3 0.0391672
RABGAP1L RAB GTPase activating protein 1-like 0.0390704
EFNA5 ephrin-A5 0.0388061
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.0384334
DUSP4 dual specificity phosphatase 4 0.0380423
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0378667
AHNAK2 AHNAK nucleoprotein 2 0.0375166
RAI14 retinoic acid induced 14 0.0367627
NIBAN2 niban apoptosis regulator 2 0.0351544
SULF1 sulfatase 1 0.0347564
NEK7 NIMA-related kinase 7 0.0347146
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.0343521
POTEF POTE ankyrin domain family, member F 0.0341866
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.0341853
CUL4B cullin 4B 0.0340323
BCAR3 breast cancer anti-estrogen resistance 3 0.033842
DPYD dihydropyrimidine dehydrogenase 0.0337374
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0328133
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.0326801
DOCK5 dedicator of cytokinesis 5 0.0322582
SULF2 sulfatase 2 0.03208
SRRM2 serine/arginine repetitive matrix 2 0.0315197
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0309573
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0307956
CALB1 calbindin 1, 28kDa 0.0296138
TSC22D1 TSC22 domain family, member 1 0.0292757
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0289935
AFF4 AF4/FMR2 family, member 4 0.0286448
BCL2L1 BCL2-like 1 0.0285432
RPL4 ribosomal protein L4 0.0282486
KIAA0040 KIAA0040 0.0282328
CLMB calcimembrin 0.0280691
NRG1 neuregulin 1 0.0279241
DST dystonin 0.0278515
ANKRD28 ankyrin repeat domain 28 0.0275336
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0275187
SET SET nuclear proto-oncogene 0.0275038
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0273444
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0268381
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0265546
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0265346
AFAP1 actin filament associated protein 1 0.0264971
ADAR adenosine deaminase, RNA-specific 0.0264741
GRAMD1B GRAM domain containing 1B 0.0263541
BLCAP bladder cancer associated protein 0.0263346
PDLIM1 PDZ and LIM domain 1 0.0261157
BMAL2 basic helix-loop-helix ARNT like 2 0.0259953
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.025973
ASPH aspartate beta-hydroxylase 0.0258473
CKAP5 cytoskeleton associated protein 5 0.0256682
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0256402
DPYSL2 dihydropyrimidinase-like 2 0.0254422
TMC5 transmembrane channel-like 5 0.0253712
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0253283
DOCK9 dedicator of cytokinesis 9 0.0253162
LNPEP leucyl/cystinyl aminopeptidase 0.0253092
OGA O-GlcNAcase 0.025271
SERINC3 serine incorporator 3 0.025201
ITGA6 integrin, alpha 6 0.0244772
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0242312
PCDH1 protocadherin 1 0.024046
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0240028
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0239773
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0239674
EIF4B eukaryotic translation initiation factor 4B 0.0239541
TMSB4X thymosin beta 4, X-linked 0.023639
TLN1 talin 1 0.0236243
ACTG1 actin gamma 1 0.0235782
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.023243

decreased expression

Symbol Name Standardized Value
NDRG1 N-myc downstream regulated 1 -0.123741
TIMP3 TIMP metallopeptidase inhibitor 3 -0.104842
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0821049
INTS6 integrator complex subunit 6 -0.0803885
IGF2 insulin-like growth factor 2 -0.0791722
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0766804
RPS21 ribosomal protein S21 -0.0675194
TMSB10 thymosin beta 10 -0.0647071
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0623444
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0601956
RCOR1 REST corepressor 1 -0.0594914
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0582811
LAMA5 laminin, alpha 5 -0.0519792
RBM39 RNA binding motif protein 39 -0.0473283
TPT1 tumor protein, translationally-controlled 1 -0.0466554
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0461483
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0442661
GNAS GNAS complex locus -0.0441917
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0433243
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 -0.0420689
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0406555
ZCCHC7 zinc finger, CCHC domain containing 7 -0.039917
HM13 histocompatibility (minor) 13 -0.03981
UBE2H ubiquitin-conjugating enzyme E2H -0.0395475
S100A10 S100 calcium binding protein A10 -0.0393671
RPS24 ribosomal protein S24 -0.0385358
PSD3 pleckstrin and Sec7 domain containing 3 -0.0384359
SPAG9 sperm associated antigen 9 -0.0381579
RAP1B RAP1B, member of RAS oncogene family -0.0373226
SEC24A SEC24 family member A -0.0361107
RPS6 ribosomal protein S6 -0.0358262
MORF4L2 mortality factor 4 like 2 -0.0352898
PTMA prothymosin, alpha -0.0352007
ARF4 ADP-ribosylation factor 4 -0.0348948
RPLP2 ribosomal protein, large, P2 -0.0348747
MT2A metallothionein 2A -0.0340045
MTSS1 metastasis suppressor 1 -0.0339926
ANKRD11 ankyrin repeat domain 11 -0.0338718
COPA coatomer protein complex, subunit alpha -0.0336581
MT1X metallothionein 1X -0.0333233
RAB2A RAB2A, member RAS oncogene family -0.0323777
SEC31A SEC31 homolog A (S. cerevisiae) -0.0319744
NT5C2 5'-nucleotidase, cytosolic II -0.0319517
COG6 component of oligomeric golgi complex 6 -0.031906
SLC35F3 solute carrier family 35, member F3 -0.0316838
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -0.0313537
TRA2A transformer 2 alpha homolog (Drosophila) -0.0312722
IARS1 isoleucyl-tRNA synthetase 1 -0.0309872
UFM1 ubiquitin-fold modifier 1 -0.0308866
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0306229
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0305336
HMGA1 high mobility group AT-hook 1 -0.0303973
RAB7A RAB7A, member RAS oncogene family -0.0301795
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0296602
GARS1 glycyl-tRNA synthetase 1 -0.0296235
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0294135
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0293485
MBOAT2 membrane bound O-acyltransferase domain containing 2 -0.0293009
SRP54 signal recognition particle 54kDa -0.0290617
PDE4D phosphodiesterase 4D, cAMP-specific -0.0288719
RPL11 ribosomal protein L11 -0.0288138
ITCH itchy E3 ubiquitin protein ligase -0.0283836
TTC3 tetratricopeptide repeat domain 3 -0.0279608
SBF2 SET binding factor 2 -0.0277186
CLINT1 clathrin interactor 1 -0.0275556
H1-0 H1.0 linker histone -0.0272333
HSPG2 heparan sulfate proteoglycan 2 -0.0270696
PFN1 profilin 1 -0.0269654
PNISR PNN-interacting serine/arginine-rich protein -0.0268757
FSCN1 fascin actin-bundling protein 1 -0.0266258
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0261941
SEC24D SEC24 family member D -0.0259966
CDK13 cyclin-dependent kinase 13 -0.0259418
RPL35A ribosomal protein L35a -0.0259243
KMT2E lysine (K)-specific methyltransferase 2E -0.0257469
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0255211
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0253962
STC1 stanniocalcin 1 -0.0252751
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0251298
PDLIM5 PDZ and LIM domain 5 -0.0249147
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0247562
MDK midkine (neurite growth-promoting factor 2) -0.0246607
SCFD1 sec1 family domain containing 1 -0.0245304
LMAN1 lectin, mannose-binding, 1 -0.0244065
TMEM165 transmembrane protein 165 -0.0242788
RPL34 ribosomal protein L34 -0.0238721
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0237663
WSB1 WD repeat and SOCS box containing 1 -0.0236891
SLC38A2 solute carrier family 38, member 2 -0.0234634
JMJD1C jumonji domain containing 1C -0.0234295
ALCAM activated leukocyte cell adhesion molecule -0.0233875
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.0233186
ESYT2 extended synaptotagmin-like protein 2 -0.0232411
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.023164
ABI3BP ABI family, member 3 (NESH) binding protein -0.0230882
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0230705
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0230222
TNS3 tensin 3 -0.0228904
EGFR epidermal growth factor receptor -0.0227413
TBC1D23 TBC1 domain family, member 23 -0.0226487