Gallic acid_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in J82 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ENO1 enolase 1, (alpha) 0.215077
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.189772
MT2A metallothionein 2A 0.167526
AHNAK AHNAK nucleoprotein 0.150776
POTEF POTE ankyrin domain family, member F 0.125949
MYH9 myosin, heavy chain 9, non-muscle 0.121563
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.111303
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0843778
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0703297
SET SET nuclear proto-oncogene 0.0654494
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0651701
ERBIN erbb2 interacting protein 0.0592312
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0579754
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0568861
ACTG1 actin gamma 1 0.0567998
MCL1 myeloid cell leukemia 1 0.0560759
FLNB filamin B, beta 0.055898
RPL23 ribosomal protein L23 0.0545113
CD44 CD44 molecule (Indian blood group) 0.0534045
ASPH aspartate beta-hydroxylase 0.0529495
CALR calreticulin 0.0504836
TPM3 tropomyosin 3 0.0502403
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0497314
LDHA lactate dehydrogenase A 0.0493427
EEF2 eukaryotic translation elongation factor 2 0.0491661
PCBP2 poly(rC) binding protein 2 0.0481078
ACTN1 actinin, alpha 1 0.0479719
ZNF841 zinc finger protein 841 0.0467879
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0466626
BZW1 basic leucine zipper and W2 domains 1 0.0455388
EIF4A1 eukaryotic translation initiation factor 4A1 0.0438574
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0434245
UBC ubiquitin C 0.0423811
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0405525
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0387455
SFPQ splicing factor proline/glutamine-rich 0.0381972
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0368429
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0367784
RPS3 ribosomal protein S3 0.036525
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.0362488
DST dystonin 0.0361268
CORO1C coronin, actin binding protein, 1C 0.0357604
FLNA filamin A, alpha 0.0355515
RPS27A ribosomal protein S27a 0.0339659
NIBAN2 niban apoptosis regulator 2 0.0339497
SH3RF1 SH3 domain containing ring finger 1 0.0327563
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0324926
SLC12A8 solute carrier family 12, member 8 0.0324475
YBX1 Y box binding protein 1 0.0322474
HSPA8 heat shock 70kDa protein 8 0.0320487
APLP2 amyloid beta (A4) precursor-like protein 2 0.0316699
AKAP12 A kinase (PRKA) anchor protein 12 0.0316601
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.031485
PTPRG protein tyrosine phosphatase, receptor type, G 0.0308991
APP amyloid beta (A4) precursor protein 0.0306777
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0300015
PDLIM5 PDZ and LIM domain 5 0.0296252
RPS12 ribosomal protein S12 0.0295591
DIAPH1 diaphanous-related formin 1 0.0290274
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0285611
RPL37 ribosomal protein L37 0.0283465
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.028088
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028016
PTK2 protein tyrosine kinase 2 0.027949
RPL4 ribosomal protein L4 0.0277432
KRT8 keratin 8, type II 0.0277363
SMC1A structural maintenance of chromosomes 1A 0.0277204
RPL3 ribosomal protein L3 0.0274238
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0270631
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0269429
CSDE1 cold shock domain containing E1, RNA-binding 0.0264934
RPS8 ribosomal protein S8 0.0257596
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0255687
COL5A1 collagen, type V, alpha 1 0.0250176
PTMA prothymosin, alpha 0.0249882
RPS17 ribosomal protein S17 0.0249779
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0249565
PODXL podocalyxin-like 0.0249518
NRIP1 nuclear receptor interacting protein 1 0.0246475
COL7A1 collagen, type VII, alpha 1 0.0245772
MACF1 microtubule-actin crosslinking factor 1 0.0245496
COL3A1 collagen, type III, alpha 1 0.0244645
ARB2A ARB2 cotranscriptional regulator A 0.0242501
SDC4 syndecan 4 0.0239032
MSN moesin 0.0236952
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0230005
ANXA5 annexin A5 0.0226881
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 0.0222499
NFE2L1 nuclear factor, erythroid 2-like 1 0.0216473
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0215231
RAD51B RAD51 paralog B 0.0213423
FBL fibrillarin 0.0212639
EIF4B eukaryotic translation initiation factor 4B 0.0211744
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0210799
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0210434
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.020774
PLEC plectin 0.0204851
IGF1R insulin-like growth factor 1 receptor 0.0203338
CEP250 centrosomal protein 250kDa 0.0201712
AXL AXL receptor tyrosine kinase 0.0200279

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.169688
TRIO trio Rho guanine nucleotide exchange factor -0.143494
FN1 fibronectin 1 -0.13933
ABI3BP ABI family, member 3 (NESH) binding protein -0.136167
HLA-B major histocompatibility complex, class I, B -0.126444
UGCG UDP-glucose ceramide glucosyltransferase -0.114692
NDRG1 N-myc downstream regulated 1 -0.114273
IGFBP3 insulin-like growth factor binding protein 3 -0.105643
DLG1 discs, large homolog 1 (Drosophila) -0.104136
FTL ferritin, light polypeptide -0.0953802
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0756271
PLCB4 phospholipase C, beta 4 -0.0671525
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0560328
CTSD cathepsin D -0.0550329
NALF1 NALCN channel auxiliary factor 1 -0.0543908
ARF4 ADP-ribosylation factor 4 -0.0531305
CCBE1 collagen and calcium binding EGF domains 1 -0.0520008
GOLGA4 golgin A4 -0.0497238
FNDC3B fibronectin type III domain containing 3B -0.0492438
NUP58 nucleoporin 58 -0.047143
F3 coagulation factor III (thromboplastin, tissue factor) -0.0464326
TGFB2 transforming growth factor, beta 2 -0.0456732
RBM39 RNA binding motif protein 39 -0.0456546
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0435208
POSTN periostin, osteoblast specific factor -0.0433314
SPAG9 sperm associated antigen 9 -0.0431738
TRAM1 translocation associated membrane protein 1 -0.043089
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0427704
TSC22D2 TSC22 domain family, member 2 -0.0410387
DIAPH3 diaphanous-related formin 3 -0.0399044
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0389218
ADM adrenomedullin -0.0389127
SUCO SUN domain containing ossification factor -0.0379691
TXNRD1 thioredoxin reductase 1 -0.03726
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0371732
SBF2 SET binding factor 2 -0.0371131
ZNF292 zinc finger protein 292 -0.0364965
GOLT1B golgi transport 1B -0.0362167
WSB1 WD repeat and SOCS box containing 1 -0.035835
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0356384
PDIA3 protein disulfide isomerase family A, member 3 -0.0354301
LMAN1 lectin, mannose-binding, 1 -0.0353672
FTH1 ferritin, heavy polypeptide 1 -0.0351237
SULF1 sulfatase 1 -0.0350919
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0350443
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0343783
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0341905
NOP58 NOP58 ribonucleoprotein -0.0340128
TPD52 tumor protein D52 -0.0338822
ZNF432 zinc finger protein 432 -0.0335578
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0333673
ITCH itchy E3 ubiquitin protein ligase -0.0331618
KMT2E lysine (K)-specific methyltransferase 2E -0.0330016
COPB1 coatomer protein complex, subunit beta 1 -0.0328976
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.0323378
RLF rearranged L-myc fusion -0.0320871
ELL2 elongation factor, RNA polymerase II, 2 -0.0316558
PTBP3 polypyrimidine tract binding protein 3 -0.0316403
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0315887
PHACTR1 phosphatase and actin regulator 1 -0.0311026
BBX bobby sox homolog (Drosophila) -0.0310389
MORF4L2 mortality factor 4 like 2 -0.0310266
UFM1 ubiquitin-fold modifier 1 -0.0309901
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0306735
RAB6A RAB6A, member RAS oncogene family -0.0304767
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.029984
SEC31A SEC31 homolog A (S. cerevisiae) -0.0296439
SAMD12 sterile alpha motif domain containing 12 -0.0294619
SEC24A SEC24 family member A -0.0294218
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0289853
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0288395
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0287509
ZNF804A zinc finger protein 804A -0.0286953
NUP98 nucleoporin 98kDa -0.0286041
TUBB tubulin, beta class I -0.0283206
SRP54 signal recognition particle 54kDa -0.0282829
GNAS GNAS complex locus -0.0281738
SOD2 superoxide dismutase 2, mitochondrial -0.0279954
CCNL1 cyclin L1 -0.0278993
RPS6 ribosomal protein S6 -0.0276063
LCORL ligand dependent nuclear receptor corepressor-like -0.0274704
IL6ST interleukin 6 signal transducer -0.0273345
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0272897
STK4 serine/threonine kinase 4 -0.0272819
PHF21A PHD finger protein 21A -0.0268335
NAMPT nicotinamide phosphoribosyltransferase -0.0268119
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0264681
PFN1 profilin 1 -0.0263414
SCAF11 SR-related CTD-associated factor 11 -0.0260333
CCDC80 coiled-coil domain containing 80 -0.0259634
ANKRD10 ankyrin repeat domain 10 -0.0259555
GLIS3 GLIS family zinc finger 3 -0.0254997
QKI QKI, KH domain containing, RNA binding -0.0253473
KMT2C lysine (K)-specific methyltransferase 2C -0.0252094
MAP4 microtubule-associated protein 4 -0.0250037
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 -0.0249955
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.0248436
NSD3 nuclear receptor binding SET domain protein 3 -0.0247783
ARF1 ADP-ribosylation factor 1 -0.0246509
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0244396