Gallic acid_LS 180 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in LS 180 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FAT1 FAT atypical cadherin 1 0.0837979
POTEF POTE ankyrin domain family, member F 0.0607882
VEGFA vascular endothelial growth factor A 0.0565219
LMO7 LIM domain 7 0.0544308
RPL3 ribosomal protein L3 0.0407391
MUC6 mucin 6, oligomeric mucus/gel-forming 0.0380378
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0370936
EEF2 eukaryotic translation elongation factor 2 0.0348223
CALR calreticulin 0.0342493
ACTG1 actin gamma 1 0.0324945
RNF145 ring finger protein 145 0.0324216
FTH1 ferritin, heavy polypeptide 1 0.0303457
ENO2 enolase 2 (gamma, neuronal) 0.0291599
MED13 mediator complex subunit 13 0.0290889
PCBP2 poly(rC) binding protein 2 0.0288879
SFPQ splicing factor proline/glutamine-rich 0.0284216
CEMIP cell migration inducing protein, hyaluronan binding 0.0283361
APLP2 amyloid beta (A4) precursor-like protein 2 0.0278658
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0268498
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0267805
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0237348
CENPF centromere protein F, 350/400kDa 0.0232647
SRRM2 serine/arginine repetitive matrix 2 0.0231898
PTMA prothymosin, alpha 0.0221872
SLK STE20-like kinase 0.0220319
MCL1 myeloid cell leukemia 1 0.0211783
DSPP dentin sialophosphoprotein 0.0210279
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.0206806
MYH9 myosin, heavy chain 9, non-muscle 0.0206622
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0206037
PTEN phosphatase and tensin homolog 0.0203414
EIF4B eukaryotic translation initiation factor 4B 0.0203402
ENO1 enolase 1, (alpha) 0.0202118
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0200958
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.019902
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0195218
ASPH aspartate beta-hydroxylase 0.0194819
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0194155
USP6NL USP6 N-terminal like 0.0193383
PDZD8 PDZ domain containing 8 0.0191985
CTBP2 C-terminal binding protein 2 0.0188874
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0185118
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0183226
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.018252
RPLP2 ribosomal protein, large, P2 0.0181314
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0172929
DPY19L1 dpy-19-like 1 (C. elegans) 0.0172596
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0171888
NCOR2 nuclear receptor corepressor 2 0.0169873
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0169441
ARHGAP42 Rho GTPase activating protein 42 0.0168728
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0168396
EFNA5 ephrin-A5 0.0166021
SRSF11 serine/arginine-rich splicing factor 11 0.0164773
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0164655
SPRED2 sprouty-related, EVH1 domain containing 2 0.0163616
SRP54 signal recognition particle 54kDa 0.0161994
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0161898
PNN pinin, desmosome associated protein 0.0159859
TPM3 tropomyosin 3 0.015969
RPL36 ribosomal protein L36 0.0157904
PCM1 pericentriolar material 1 0.0157845
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.015419
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0152461
PLEC plectin 0.0152181
ZNF148 zinc finger protein 148 0.0151937
ADARB1 adenosine deaminase, RNA-specific, B1 0.0151318
HYOU1 hypoxia up-regulated 1 0.0150512
KRT8 keratin 8, type II 0.0147987
VIM vimentin 0.0147387
EIF4A1 eukaryotic translation initiation factor 4A1 0.0147203
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.0145736
KTN1 kinectin 1 (kinesin receptor) 0.014565
SRSF4 serine/arginine-rich splicing factor 4 0.0142645
ITGA6 integrin, alpha 6 0.0141153
SEC23A Sec23 homolog A (S. cerevisiae) 0.0140765
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0139437
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0138769
MUC13 mucin 13, cell surface associated 0.0137482
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0136545
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.0134878
PRRC2C proline-rich coiled-coil 2C 0.0134681
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 0.0133804
TMF1 TATA element modulatory factor 1 0.0133032
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0132311
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0131771
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0131691
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0131429
RELCH RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing 0.0130766
MINK1 misshapen-like kinase 1 0.0130616
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.0130052
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.0129414
CKAP5 cytoskeleton associated protein 5 0.0128614
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0127884
WNK1 WNK lysine deficient protein kinase 1 0.012679
MYO6 myosin VI 0.0126754
COPA coatomer protein complex, subunit alpha 0.0126644
RPS3 ribosomal protein S3 0.0126361
KMT2D lysine (K)-specific methyltransferase 2D 0.0125903
IQGAP3 IQ motif containing GTPase activating protein 3 0.0124761

decreased expression

Symbol Name Standardized Value
NPSR1 neuropeptide S receptor 1 -0.249361
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.21787
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.149099
TPT1 tumor protein, translationally-controlled 1 -0.114516
VCL vinculin -0.11082
MYO1E myosin IE -0.096806
PIGR polymeric immunoglobulin receptor -0.0944052
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0874393
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0850196
ANTXR2 anthrax toxin receptor 2 -0.0834922
NALF1 NALCN channel auxiliary factor 1 -0.0819813
ANXA2 annexin A2 -0.0780596
TMSB10 thymosin beta 10 -0.0730768
ALCAM activated leukocyte cell adhesion molecule -0.0724533
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0658771
GMDS GDP-mannose 4,6-dehydratase -0.064427
TPM4 tropomyosin 4 -0.0616514
PTPRK protein tyrosine phosphatase, receptor type, K -0.0591178
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0584344
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0582711
GPHN gephyrin -0.0581903
PATJ PATJ crumbs cell polarity complex component -0.0577686
GREB1L growth regulation by estrogen in breast cancer-like -0.0573967
SLC35F3 solute carrier family 35, member F3 -0.0552906
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -0.0548918
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0546689
FHIT fragile histidine triad -0.0526556
CCSER1 coiled-coil serine-rich protein 1 -0.0519615
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0517129
PTPRB protein tyrosine phosphatase, receptor type, B -0.0511794
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.04766
PDLIM5 PDZ and LIM domain 5 -0.0456888
KLF6 Kruppel-like factor 6 -0.0455525
GCC2 GRIP and coiled-coil domain containing 2 -0.0445265
PDE4D phosphodiesterase 4D, cAMP-specific -0.0445006
MAML2 mastermind-like 2 (Drosophila) -0.0444592
ONECUT3 one cut homeobox 3 -0.0442089
TAS2R14 taste receptor, type 2, member 14 -0.0438322
PALLD palladin, cytoskeletal associated protein -0.0435944
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0431897
RPLP0 ribosomal protein, large, P0 -0.0426109
PRELID2 PRELI domain containing 2 -0.042044
LPP LIM domain containing preferred translocation partner in lipoma -0.0408959
EPCAM epithelial cell adhesion molecule -0.0408258
ARHGAP5 Rho GTPase activating protein 5 -0.0407341
DENND1A DENN/MADD domain containing 1A -0.0406396
MBNL2 muscleblind-like splicing regulator 2 -0.0399543
RIGI RNA sensor RIG-I -0.0397672
MAML3 mastermind-like 3 (Drosophila) -0.0386761
H1-0 H1.0 linker histone -0.0382253
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0380703
CADPS Ca++-dependent secretion activator -0.0378479
RPS24 ribosomal protein S24 -0.0376408
DIAPH2 diaphanous-related formin 2 -0.0375573
GRB10 growth factor receptor-bound protein 10 -0.0375447
PPARG peroxisome proliferator-activated receptor gamma -0.0369068
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -0.0365557
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.0364399
FERMT1 fermitin family member 1 -0.0363456
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 -0.0359629
KLF5 Kruppel-like factor 5 (intestinal) -0.0359396
S100A6 S100 calcium binding protein A6 -0.035386
AGR2 anterior gradient 2 -0.0353706
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0352414
POF1B premature ovarian failure, 1B -0.034999
BIRC6 baculoviral IAP repeat containing 6 -0.0340956
RTN3 reticulon 3 -0.0335872
ERRFI1 ERBB receptor feedback inhibitor 1 -0.0335025
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0333828
RPL34 ribosomal protein L34 -0.0333642
ARHGAP6 Rho GTPase activating protein 6 -0.033145
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.0325638
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough -0.0323185
EXT1 exostosin glycosyltransferase 1 -0.0322676
NFIA nuclear factor I/A -0.0322613
FNDC3B fibronectin type III domain containing 3B -0.0322542
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.0321124
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0319999
BACE2 beta-site APP-cleaving enzyme 2 -0.0316771
NDRG1 N-myc downstream regulated 1 -0.0316491
IER3 immediate early response 3 -0.0315031
TMEM123 transmembrane protein 123 -0.0312689
SAMD5 sterile alpha motif domain containing 5 -0.031129
RAP1B RAP1B, member of RAS oncogene family -0.0309037
PKP2 plakophilin 2 -0.0306248
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0304166
ARF1 ADP-ribosylation factor 1 -0.0301729
CCND1 cyclin D1 -0.0301327
NEBL nebulette -0.0300274
SBF2 SET binding factor 2 -0.0298447
NRN1 neuritin 1 -0.0297956
CANX calnexin -0.0296963
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0293696
RPS6 ribosomal protein S6 -0.0291604
CDK13 cyclin-dependent kinase 13 -0.028814
MBD5 methyl-CpG binding domain protein 5 -0.0282226
ANKRD17 ankyrin repeat domain 17 -0.0281973
BZW1 basic leucine zipper and W2 domains 1 -0.0281957
FAAH2 fatty acid amide hydrolase 2 -0.0281779
RPL26 ribosomal protein L26 -0.0280664