Gallic acid_NCI-H2030 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Gallic acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GRAMD1B GRAM domain containing 1B 0.195968
PM20D1 peptidase M20 domain containing 1 0.145353
THSD4 thrombospondin, type I, domain containing 4 0.115044
PDE4D phosphodiesterase 4D, cAMP-specific 0.107928
AKAP12 A kinase (PRKA) anchor protein 12 0.1024
MCL1 myeloid cell leukemia 1 0.0863806
DOCK4 dedicator of cytokinesis 4 0.084075
AHNAK AHNAK nucleoprotein 0.0799086
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0791795
BASP1 brain abundant, membrane attached signal protein 1 0.0790529
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0790071
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.0785915
ACTG1 actin gamma 1 0.0759484
SMOC1 SPARC related modular calcium binding 1 0.0689403
FLNB filamin B, beta 0.0639659
CMIP c-Maf inducing protein 0.0602627
SAMD4A sterile alpha motif domain containing 4A 0.0513133
DOCK5 dedicator of cytokinesis 5 0.0461098
UBASH3B ubiquitin associated and SH3 domain containing B 0.0458836
KYNU kynureninase 0.0450098
SVIL supervillin 0.0440427
ENO1 enolase 1, (alpha) 0.042582
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0424253
FAM107B family with sequence similarity 107, member B 0.0419608
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0416298
LDHA lactate dehydrogenase A 0.0401132
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0396029
FMNL2 formin-like 2 0.0386551
POTEF POTE ankyrin domain family, member F 0.037973
ACTN1 actinin, alpha 1 0.0367879
MAML3 mastermind-like 3 (Drosophila) 0.0359594
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0358296
EFNA5 ephrin-A5 0.0346153
ARHGAP26 Rho GTPase activating protein 26 0.0339583
BCAR3 breast cancer anti-estrogen resistance 3 0.0331287
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.0329973
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0328302
PYGL phosphorylase, glycogen, liver 0.0325809
BICC1 BicC family RNA binding protein 1 0.0318261
RAD51B RAD51 paralog B 0.0314949
FTH1 ferritin, heavy polypeptide 1 0.0314224
ANGPTL4 angiopoietin-like 4 0.031298
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0310666
NRG1 neuregulin 1 0.0305003
TCIM transcriptional and immune response regulator 0.030395
SFPQ splicing factor proline/glutamine-rich 0.0302588
IGFBP3 insulin-like growth factor binding protein 3 0.0295426
GLIS3 GLIS family zinc finger 3 0.0285619
EXT1 exostosin glycosyltransferase 1 0.0284561
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.027596
ELL2 elongation factor, RNA polymerase II, 2 0.0272305
UTRN utrophin 0.0269517
PTPRM protein tyrosine phosphatase, receptor type, M 0.0267812
HDAC9 histone deacetylase 9 0.0267333
DST dystonin 0.0266666
APP amyloid beta (A4) precursor protein 0.0264929
LAMC2 laminin, gamma 2 0.0262968
EEF2 eukaryotic translation elongation factor 2 0.0261794
NEBL nebulette 0.0253626
EIF4A1 eukaryotic translation initiation factor 4A1 0.0252111
AGO2 argonaute RISC catalytic component 2 0.0250732
EGFR epidermal growth factor receptor 0.0245159
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0244292
ANKRD11 ankyrin repeat domain 11 0.0243416
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0243298
NPAS2 neuronal PAS domain protein 2 0.0243201
RPL3 ribosomal protein L3 0.023435
OSMR oncostatin M receptor 0.0233964
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0233045
TIMP1 TIMP metallopeptidase inhibitor 1 0.0231991
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.0228618
PDE10A phosphodiesterase 10A 0.0226788
MYH9 myosin, heavy chain 9, non-muscle 0.0225604
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.0222768
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0221863
TTC28 tetratricopeptide repeat domain 28 0.0221129
TRIP11 thyroid hormone receptor interactor 11 0.0221083
PTPRG protein tyrosine phosphatase, receptor type, G 0.0220368
FOXP1 forkhead box P1 0.0218767
PLS3 plastin 3 0.0217124
APLP2 amyloid beta (A4) precursor-like protein 2 0.0217025
RNF213 ring finger protein 213 0.0215674
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0213753
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.0213049
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0212976
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.0211967
WWOX WW domain containing oxidoreductase 0.0210124
MACF1 microtubule-actin crosslinking factor 1 0.0209671
PARD3B par-3 family cell polarity regulator beta 0.0209524
AHNAK2 AHNAK nucleoprotein 2 0.0209426
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 0.0207851
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0207752
GRB10 growth factor receptor-bound protein 10 0.0206558
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0206145
NTN4 netrin 4 0.0205154
CTBP2 C-terminal binding protein 2 0.0203594
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0203098
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0198053
CFLAR CASP8 and FADD-like apoptosis regulator 0.0198013
NPC1 Niemann-Pick disease, type C1 0.0197396

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.297976
FTL ferritin, light polypeptide -0.118655
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.107878
TFPI2 tissue factor pathway inhibitor 2 -0.105941
RTN4 reticulon 4 -0.0799042
TM4SF1 transmembrane 4 L six family member 1 -0.0793716
IGF2 insulin-like growth factor 2 -0.0757861
RPL19 ribosomal protein L19 -0.0732502
EIF1 eukaryotic translation initiation factor 1 -0.065268
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0630337
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0603486
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0603485
PTMA prothymosin, alpha -0.0600919
MT2A metallothionein 2A -0.0598991
FGB fibrinogen beta chain -0.0593886
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0577677
RPS2 ribosomal protein S2 -0.057078
DENND4A DENN/MADD domain containing 4A -0.0564956
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0528836
ZFAND3 zinc finger, AN1-type domain 3 -0.0503612
RPS6 ribosomal protein S6 -0.0500492
YBX3 Y box binding protein 3 -0.0481816
WDR43 WD repeat domain 43 -0.0480739
RPS25 ribosomal protein S25 -0.0472335
IER3 immediate early response 3 -0.0454304
RBM39 RNA binding motif protein 39 -0.044239
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0440903
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0435134
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.0432949
EIF3H eukaryotic translation initiation factor 3, subunit H -0.0432716
USP3 ubiquitin specific peptidase 3 -0.0419875
RPL7 ribosomal protein L7 -0.0417768
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0409328
NOP58 NOP58 ribonucleoprotein -0.0396529
KHDC4 KH domain containing 4, pre-mRNA splicing factor -0.0392826
GOLT1B golgi transport 1B -0.0389012
NAMPT nicotinamide phosphoribosyltransferase -0.038886
MIS18BP1 MIS18 binding protein 1 -0.0387102
ATP5F1B ATP synthase F1 subunit beta -0.0386481
RAD21 RAD21 homolog (S. pombe) -0.0384929
RPS21 ribosomal protein S21 -0.0383069
SLC38A1 solute carrier family 38, member 1 -0.0369871
ZNF292 zinc finger protein 292 -0.0367454
S100A10 S100 calcium binding protein A10 -0.0363926
RPS23 ribosomal protein S23 -0.0356742
RPS5 ribosomal protein S5 -0.0356713
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -0.0352261
PFDN2 prefoldin subunit 2 -0.0352038
HMGA1 high mobility group AT-hook 1 -0.0349784
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0348127
SPAG9 sperm associated antigen 9 -0.0344519
RHEB Ras homolog enriched in brain -0.0342668
TMEM123 transmembrane protein 123 -0.0339956
CYRIB CYFIP related Rac1 interactor B -0.0336737
RPL8 ribosomal protein L8 -0.0335338
RPS12 ribosomal protein S12 -0.0333707
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.0333028
QKI QKI, KH domain containing, RNA binding -0.0323235
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.031516
NUP58 nucleoporin 58 -0.0310554
SERF2 small EDRK-rich factor 2 -0.0307577
CAMTA1 calmodulin binding transcription activator 1 -0.030575
SRGN serglycin -0.0304956
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0300893
TPX2 TPX2, microtubule-associated -0.0299352
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0295836
PDIA3 protein disulfide isomerase family A, member 3 -0.0295156
TFG TRK-fused gene -0.0292373
KMT2E lysine (K)-specific methyltransferase 2E -0.0291826
TMSB10 thymosin beta 10 -0.0291473
TPD52 tumor protein D52 -0.0291188
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0289632
RPS15 ribosomal protein S15 -0.0289008
BCLAF1 BCL2-associated transcription factor 1 -0.0287227
PFN1 profilin 1 -0.0286211
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0285878
TXNRD1 thioredoxin reductase 1 -0.0281912
TRA2B transformer 2 beta homolog (Drosophila) -0.0281033
LDHB lactate dehydrogenase B -0.0280233
FXR1 fragile X mental retardation, autosomal homolog 1 -0.0279275
TPT1 tumor protein, translationally-controlled 1 -0.0276813
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0276554
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0274893
RPS16 ribosomal protein S16 -0.0274096
RPS29 ribosomal protein S29 -0.0273854
UPP1 uridine phosphorylase 1 -0.0273676
RPL5 ribosomal protein L5 -0.0271891
CCNL1 cyclin L1 -0.027053
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0268809
NUSAP1 nucleolar and spindle associated protein 1 -0.0265305
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.0262713
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.0260117
RFWD3 ring finger and WD repeat domain 3 -0.0256524
TRA2A transformer 2 alpha homolog (Drosophila) -0.0256056
CHN1 chimerin 1 -0.0254183
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0253665
NCEH1 neutral cholesterol ester hydrolase 1 -0.0253398
WTAP Wilms tumor 1 associated protein -0.0251833
KTN1 kinectin 1 (kinesin receptor) -0.0251824
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -0.0251257