Gallic acid_NCI-H23 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in NCI-H23 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.264545
GRAMD1B GRAM domain containing 1B 0.126439
MCL1 myeloid cell leukemia 1 0.10522
ERRFI1 ERBB receptor feedback inhibitor 1 0.101446
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0615683
PDE4D phosphodiesterase 4D, cAMP-specific 0.0608223
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.0606738
ELL2 elongation factor, RNA polymerase II, 2 0.0585052
POTEF POTE ankyrin domain family, member F 0.0553001
MYH9 myosin, heavy chain 9, non-muscle 0.0499551
YAP1 Yes-associated protein 1 0.0486799
AHNAK AHNAK nucleoprotein 0.0481777
PDE10A phosphodiesterase 10A 0.0481307
TPM3 tropomyosin 3 0.0477499
PCBP2 poly(rC) binding protein 2 0.0465203
CSDE1 cold shock domain containing E1, RNA-binding 0.044948
WWTR1 WW domain containing transcription regulator 1 0.0440382
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0432063
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0412821
EIF4A1 eukaryotic translation initiation factor 4A1 0.0410297
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0405524
PRELID2 PRELI domain containing 2 0.0402245
WWOX WW domain containing oxidoreductase 0.0401825
HSPA8 heat shock 70kDa protein 8 0.0394799
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0391781
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0383245
VMP1 vacuole membrane protein 1 0.0372356
RPL3 ribosomal protein L3 0.0361962
RICTOR RPTOR independent companion of MTOR, complex 2 0.0360096
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0359706
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0352423
CDK17 cyclin-dependent kinase 17 0.0343382
PDLIM5 PDZ and LIM domain 5 0.0342389
COPA coatomer protein complex, subunit alpha 0.033688
ADAR adenosine deaminase, RNA-specific 0.0331888
FMNL2 formin-like 2 0.0330698
CAPRIN2 caprin family member 2 0.0328787
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.032369
DOCK5 dedicator of cytokinesis 5 0.0319507
ACTG1 actin gamma 1 0.0308291
TCIM transcriptional and immune response regulator 0.030519
TLN1 talin 1 0.0302409
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0302175
ATP13A3 ATPase type 13A3 0.0301535
CCNL1 cyclin L1 0.029086
SFPQ splicing factor proline/glutamine-rich 0.0289128
PRKCE protein kinase C, epsilon 0.0285052
EIF4B eukaryotic translation initiation factor 4B 0.0284995
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0284541
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.028068
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0279734
MACF1 microtubule-actin crosslinking factor 1 0.0276757
CAMTA1 calmodulin binding transcription activator 1 0.0270214
AFF3 AF4/FMR2 family, member 3 0.0269168
ENO1 enolase 1, (alpha) 0.0268481
UBAP2L ubiquitin associated protein 2-like 0.0265643
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.0260967
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0257696
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0257506
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0255716
SPTBN1 spectrin, beta, non-erythrocytic 1 0.025426
APP amyloid beta (A4) precursor protein 0.0252094
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0249242
MAN1A2 mannosidase, alpha, class 1A, member 2 0.0248721
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0247589
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.024563
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0243308
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0242378
TRA2A transformer 2 alpha homolog (Drosophila) 0.0240885
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0237673
ZEB1 zinc finger E-box binding homeobox 1 0.0237211
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0234374
LRPPRC leucine-rich pentatricopeptide repeat containing 0.0233392
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0233153
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0230809
DSPP dentin sialophosphoprotein 0.0229385
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0228184
CTNNBL1 catenin, beta like 1 0.0225894
FERMT2 fermitin family member 2 0.0221699
VCP valosin containing protein 0.0217122
OGA O-GlcNAcase 0.0215747
EML4 echinoderm microtubule associated protein like 4 0.021569
IPO7 importin 7 0.0214179
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0213869
CHIC2 cysteine-rich hydrophobic domain 2 0.021369
DSCAM Down syndrome cell adhesion molecule 0.021344
ZSWIM6 zinc finger, SWIM-type containing 6 0.0210992
DNMBP dynamin binding protein 0.020939
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0208272
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.0207382
MCTP1 multiple C2 domains, transmembrane 1 0.0206658
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0201837
GSK3B glycogen synthase kinase 3 beta 0.0200802
SVIL supervillin 0.0198261
BCAP31 B-cell receptor-associated protein 31 0.0195231
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0193935
AFF4 AF4/FMR2 family, member 4 0.0193892
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0193276
TM4SF1 transmembrane 4 L six family member 1 0.019275
FNDC3B fibronectin type III domain containing 3B 0.0191661

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.376595
TFPI2 tissue factor pathway inhibitor 2 -0.16545
VIM vimentin -0.114831
EGR1 early growth response 1 -0.0823749
TRIO trio Rho guanine nucleotide exchange factor -0.065756
TXNRD1 thioredoxin reductase 1 -0.0642008
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0575063
TMSB10 thymosin beta 10 -0.0514434
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0510647
KTN1 kinectin 1 (kinesin receptor) -0.0495992
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0484667
RPS21 ribosomal protein S21 -0.0465178
RPL35A ribosomal protein L35a -0.0457943
ACTR2 ARP2 actin-related protein 2 homolog (yeast) -0.0421262
NCOA7 nuclear receptor coactivator 7 -0.0402845
VDAC1 voltage-dependent anion channel 1 -0.0402376
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0387867
CCND1 cyclin D1 -0.0383415
SMC4 structural maintenance of chromosomes 4 -0.0376474
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0371686
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0353579
RPS15 ribosomal protein S15 -0.0351325
IGF2 insulin-like growth factor 2 -0.0348781
RPL11 ribosomal protein L11 -0.0343457
RPS24 ribosomal protein S24 -0.0343159
BBX bobby sox homolog (Drosophila) -0.0341935
RPL38 ribosomal protein L38 -0.0340172
TAPBP TAP binding protein (tapasin) -0.0336395
PFN1 profilin 1 -0.0333166
RTN4 reticulon 4 -0.0333032
NAP1L1 nucleosome assembly protein 1-like 1 -0.0331195
ATP5F1B ATP synthase F1 subunit beta -0.0329781
BSG basigin (Ok blood group) -0.0329091
RPL26 ribosomal protein L26 -0.0329084
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0326553
SLC38A2 solute carrier family 38, member 2 -0.0322653
RPS8 ribosomal protein S8 -0.0316115
OSBPL8 oxysterol binding protein-like 8 -0.0312947
TAS2R14 taste receptor, type 2, member 14 -0.0312094
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0307462
SPDYA speedy/RINGO cell cycle regulator family member A -0.0305882
NCAPD2 non-SMC condensin I complex, subunit D2 -0.03053
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0303296
MAP4 microtubule-associated protein 4 -0.0302927
ZNFX1 zinc finger, NFX1-type containing 1 -0.0300797
EIF5B eukaryotic translation initiation factor 5B -0.0299599
HMGA1 high mobility group AT-hook 1 -0.0296958
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0289892
RPL34 ribosomal protein L34 -0.0287366
HLA-B major histocompatibility complex, class I, B -0.0285711
EGFR epidermal growth factor receptor -0.0282574
RACK1 receptor for activated C kinase 1 -0.0275416
SBF2 SET binding factor 2 -0.0275346
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0271474
GNAS GNAS complex locus -0.0270658
ATF6 activating transcription factor 6 -0.0269981
PHACTR4 phosphatase and actin regulator 4 -0.0267286
ATXN2 ataxin 2 -0.0266951
NABP1 nucleic acid binding protein 1 -0.0266163
RPL9 ribosomal protein L9 -0.0266086
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0265086
IER3 immediate early response 3 -0.0264094
LOC112694756 uncharaterized LOC112694756 -0.0262831
LDHA lactate dehydrogenase A -0.026203
THSD4 thrombospondin, type I, domain containing 4 -0.0260483
MTPN myotrophin -0.0256458
RAD51B RAD51 paralog B -0.0255502
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.025497
PHIP pleckstrin homology domain interacting protein -0.0251326
PNISR PNN-interacting serine/arginine-rich protein -0.0250878
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0248658
LMAN1 lectin, mannose-binding, 1 -0.024865
GLO1 glyoxalase I -0.0247073
TMEM165 transmembrane protein 165 -0.0246661
ZFAND3 zinc finger, AN1-type domain 3 -0.0243694
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -0.0242163
RPLP0 ribosomal protein, large, P0 -0.0242043
RPL12 ribosomal protein L12 -0.0240616
BABAM2 BRISC and BRCA1 A complex member 2 -0.0240582
SF3B1 splicing factor 3b, subunit 1, 155kDa -0.0239123
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0238624
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0238215
TUBA1B tubulin, alpha 1b -0.0237533
RPL19 ribosomal protein L19 -0.0237248
PCNX1 pecanex 1 -0.0235447
RPS6 ribosomal protein S6 -0.0234366
DEK DEK proto-oncogene -0.0233744
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -0.0233473
RPL8 ribosomal protein L8 -0.0232284
SGO2 shugoshin 2 -0.0232077
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0231982
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0231237
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0229781
ANKRD12 ankyrin repeat domain 12 -0.0226617
WASF2 WAS protein family, member 2 -0.0225576
RPL28 ribosomal protein L28 -0.0225396
MIS18BP1 MIS18 binding protein 1 -0.0223388
SCAF11 SR-related CTD-associated factor 11 -0.0223226
TPI1 triosephosphate isomerase 1 -0.0222763
RBM25 RNA binding motif protein 25 -0.0221302