Gallic acid_NCI-H460 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in NCI-H460 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PM20D1 peptidase M20 domain containing 1 0.241023
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.179953
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.134118
GDA guanine deaminase 0.126084
COL5A2 collagen, type V, alpha 2 0.124556
DST dystonin 0.105255
BZW1 basic leucine zipper and W2 domains 1 0.0963055
COL8A1 collagen, type VIII, alpha 1 0.0837644
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0764498
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0693282
AHNAK AHNAK nucleoprotein 0.0685857
EEF2 eukaryotic translation elongation factor 2 0.0685003
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0659247
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0651103
MCL1 myeloid cell leukemia 1 0.0638753
KYNU kynureninase 0.0615602
GRAMD1B GRAM domain containing 1B 0.0561656
ENO1 enolase 1, (alpha) 0.0558156
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.0542784
IGF1R insulin-like growth factor 1 receptor 0.0537803
RPL4 ribosomal protein L4 0.0532994
SH3KBP1 SH3-domain kinase binding protein 1 0.0524303
MAML3 mastermind-like 3 (Drosophila) 0.0500914
ACTG1 actin gamma 1 0.0488162
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.047903
SMOC1 SPARC related modular calcium binding 1 0.0467503
RPL23 ribosomal protein L23 0.0460553
EIF4A1 eukaryotic translation initiation factor 4A1 0.0457677
POTEF POTE ankyrin domain family, member F 0.0443863
ANXA2 annexin A2 0.0435564
ZEB2 zinc finger E-box binding homeobox 2 0.0434651
PDE10A phosphodiesterase 10A 0.0416819
PDLIM5 PDZ and LIM domain 5 0.0408905
RPS4X ribosomal protein S4, X-linked 0.0399901
SMAD2 SMAD family member 2 0.0399265
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0398262
CTIF CBP80/20-dependent translation initiation factor 0.0391771
FMNL2 formin-like 2 0.0388898
RAB3B RAB3B, member RAS oncogene family 0.0374379
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0370856
NTN4 netrin 4 0.0357106
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0356209
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 0.0338193
TMSB10 thymosin beta 10 0.0335985
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.0333557
RPLP1 ribosomal protein, large, P1 0.0331504
EZR ezrin 0.0326654
COL4A5 collagen, type IV, alpha 5 0.0322474
NPAS2 neuronal PAS domain protein 2 0.0322214
TGFBR1 transforming growth factor, beta receptor 1 0.0320535
PCBP2 poly(rC) binding protein 2 0.0320476
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0315621
FTH1 ferritin, heavy polypeptide 1 0.0299174
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.0293291
RTN1 reticulon 1 0.0290202
DNER delta/notch-like EGF repeat containing 0.0278481
INTS6 integrator complex subunit 6 0.0278322
EIF4B eukaryotic translation initiation factor 4B 0.0277751
DOCK5 dedicator of cytokinesis 5 0.0272385
KIAA0825 KIAA0825 0.0270992
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0263357
LDHA lactate dehydrogenase A 0.0262321
SAMD4A sterile alpha motif domain containing 4A 0.0260531
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0258795
RPL3 ribosomal protein L3 0.0257461
FAT1 FAT atypical cadherin 1 0.0253228
ZSWIM6 zinc finger, SWIM-type containing 6 0.0248985
MGST1 microsomal glutathione S-transferase 1 0.0244054
RPS4Y1 ribosomal protein S4, Y-linked 1 0.024294
RPS3 ribosomal protein S3 0.0242413
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.0241875
BCAR3 breast cancer anti-estrogen resistance 3 0.0239556
RPS27A ribosomal protein S27a 0.0238211
ANTXR1 anthrax toxin receptor 1 0.0234965
PTPRM protein tyrosine phosphatase, receptor type, M 0.0230501
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0227131
COL4A6 collagen, type IV, alpha 6 0.0226454
EVA1C eva-1 homolog C (C. elegans) 0.0221988
CALR calreticulin 0.0219783
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0217734
HSPA8 heat shock 70kDa protein 8 0.0216628
PHF20 PHD finger protein 20 0.0216548
DISP1 dispatched homolog 1 (Drosophila) 0.0216432
WWTR1 WW domain containing transcription regulator 1 0.0214489
APP amyloid beta (A4) precursor protein 0.0211868
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0211516
NFE2L2 nuclear factor, erythroid 2-like 2 0.0211268
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0209866
SCARA5 scavenger receptor class A, member 5 0.0207083
SORBS2 sorbin and SH3 domain containing 2 0.0206128
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.0206018
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0205438
PGK1 phosphoglycerate kinase 1 0.0204381
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.0203715
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0202716
PRKN parkin RBR E3 ubiquitin protein ligase 0.0202095
CREB3L2 cAMP responsive element binding protein 3-like 2 0.0201332
RPL12 ribosomal protein L12 0.0201201
DUSP4 dual specificity phosphatase 4 0.02001
PBX1 pre-B-cell leukemia homeobox 1 0.0199474

decreased expression

Symbol Name Standardized Value
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.117209
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0854121
NAMPT nicotinamide phosphoribosyltransferase -0.0817165
NDRG1 N-myc downstream regulated 1 -0.0779565
FNDC3B fibronectin type III domain containing 3B -0.0777742
RPS6 ribosomal protein S6 -0.0698686
ESYT2 extended synaptotagmin-like protein 2 -0.0668552
NBEAL1 neurobeachin-like 1 -0.0628741
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0586174
NRCAM neuronal cell adhesion molecule -0.0582875
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0563743
LIMCH1 LIM and calponin homology domains 1 -0.0545736
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0545264
PTPN12 protein tyrosine phosphatase, non-receptor type 12 -0.0542157
IGFBP3 insulin-like growth factor binding protein 3 -0.0490907
KMT2E lysine (K)-specific methyltransferase 2E -0.0461014
RTN4 reticulon 4 -0.0438661
WARS1 tryptophanyl-tRNA synthetase 1 -0.0424478
KTN1 kinectin 1 (kinesin receptor) -0.0410806
PTGR1 prostaglandin reductase 1 -0.0406632
PDE3A phosphodiesterase 3A, cGMP-inhibited -0.0406008
KMT2C lysine (K)-specific methyltransferase 2C -0.0387162
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0386196
PDIA3 protein disulfide isomerase family A, member 3 -0.0380632
SBF2 SET binding factor 2 -0.0375407
GOLGA4 golgin A4 -0.0367882
PCBP3 poly(rC) binding protein 3 -0.0365313
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0347504
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0346654
MYOF myoferlin -0.0345082
UBA6 ubiquitin-like modifier activating enzyme 6 -0.0344886
NALF1 NALCN channel auxiliary factor 1 -0.033259
WSB1 WD repeat and SOCS box containing 1 -0.0330326
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.032738
CTNND2 catenin (cadherin-associated protein), delta 2 -0.0325205
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.032491
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0324572
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0323496
EFNA5 ephrin-A5 -0.0321391
RPS2 ribosomal protein S2 -0.0313131
RPL9 ribosomal protein L9 -0.0312017
FAM13A family with sequence similarity 13, member A -0.0309043
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.0308385
USP34 ubiquitin specific peptidase 34 -0.0306838
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0305423
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0300592
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0298932
LSAMP limbic system-associated membrane protein -0.0298899
FNIP1 folliculin interacting protein 1 -0.0296977
LAMA5 laminin, alpha 5 -0.0296161
SPAG9 sperm associated antigen 9 -0.0294947
NUP58 nucleoporin 58 -0.029321
SLC16A6 solute carrier family 16, member 6 -0.0291783
RGS2 regulator of G-protein signaling 2 -0.0288026
SETD5 SET domain containing 5 -0.0285875
INSIG2 insulin induced gene 2 -0.0285258
MFF mitochondrial fission factor -0.0284904
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) -0.0281572
NCKAP5 NCK-associated protein 5 -0.0279578
CEP170 centrosomal protein 170kDa -0.0277518
CHD1L chromodomain helicase DNA binding protein 1-like -0.0274148
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -0.0271061
AUTS2 autism susceptibility candidate 2 -0.0268547
SUCO SUN domain containing ossification factor -0.0267071
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0264748
NBAS neuroblastoma amplified sequence -0.0264004
ADGRB3 adhesion G protein-coupled receptor B3 -0.0261302
ACBD3 acyl-CoA binding domain containing 3 -0.026043
STC1 stanniocalcin 1 -0.0259537
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0259396
TMEM165 transmembrane protein 165 -0.0258208
NCOR2 nuclear receptor corepressor 2 -0.0254755
MSN moesin -0.0254632
PRKD3 protein kinase D3 -0.0254582
SEC31A SEC31 homolog A (S. cerevisiae) -0.0252472
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -0.025107
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0250254
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.02502
COPA coatomer protein complex, subunit alpha -0.0248898
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 -0.0248105
ZFC3H1 zinc finger, C3H1-type containing -0.0246017
ZNF292 zinc finger protein 292 -0.0243366
ANO6 anoctamin 6 -0.0241671
TGFBI transforming growth factor, beta-induced, 68kDa -0.0240739
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0238127
ZMYND8 zinc finger, MYND-type containing 8 -0.023798
RAD51B RAD51 paralog B -0.0233658
BABAM2 BRISC and BRCA1 A complex member 2 -0.0228858
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0228823
CCDC88A coiled-coil domain containing 88A -0.0226529
PHF21A PHD finger protein 21A -0.0223641
KIF16B kinesin family member 16B -0.0222067
NCOA7 nuclear receptor coactivator 7 -0.0219531
BBX bobby sox homolog (Drosophila) -0.0218401
IFIH1 interferon induced with helicase C domain 1 -0.021754
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0217267
ATP5F1B ATP synthase F1 subunit beta -0.0216964
NGLY1 N-glycanase 1 -0.0216263
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.0216005
RBM25 RNA binding motif protein 25 -0.0215709