Gallic acid_SHP-77 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SHP-77 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Gallic acid_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
VGF VGF nerve growth factor inducible 0.123143
SMOC1 SPARC related modular calcium binding 1 0.113292
ENO1 enolase 1, (alpha) 0.0842603
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.060137
ACTG1 actin gamma 1 0.0597687
CHGB chromogranin B 0.056495
CPE carboxypeptidase E 0.0564448
FNDC3A fibronectin type III domain containing 3A 0.0560371
POTEF POTE ankyrin domain family, member F 0.0517916
SCG2 secretogranin II 0.0503175
COL22A1 collagen, type XXII, alpha 1 0.0465335
AOPEP aminopeptidase O (putative) 0.0438957
RNF213 ring finger protein 213 0.0429794
ADAR adenosine deaminase, RNA-specific 0.0413769
DGKD diacylglycerol kinase, delta 130kDa 0.0407479
TMSB4X thymosin beta 4, X-linked 0.0365942
PDE10A phosphodiesterase 10A 0.0360575
ARHGAP26 Rho GTPase activating protein 26 0.0356911
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0353153
MYH9 myosin, heavy chain 9, non-muscle 0.0349464
PAEP progestagen-associated endometrial protein 0.0341989
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0312712
MT2A metallothionein 2A 0.0309112
RPS12 ribosomal protein S12 0.0306888
GRAMD4 GRAM domain containing 4 0.0303699
ASPH aspartate beta-hydroxylase 0.0300678
SIK2 salt-inducible kinase 2 0.029844
FAT1 FAT atypical cadherin 1 0.029469
RPS3 ribosomal protein S3 0.0280564
SVIL supervillin 0.0273977
TMEM255B transmembrane protein 255B 0.0269856
SNAP25 synaptosomal-associated protein, 25kDa 0.0269251
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0264768
HMGB3 high mobility group box 3 0.0264117
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0260254
ASCL1 achaete-scute family bHLH transcription factor 1 0.025682
RPL3 ribosomal protein L3 0.0256676
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.0249541
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0246303
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0245864
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0243677
TPM3 tropomyosin 3 0.0243587
PCM1 pericentriolar material 1 0.0238563
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.0238108
MCL1 myeloid cell leukemia 1 0.0237502
PCBP2 poly(rC) binding protein 2 0.0234635
APLP2 amyloid beta (A4) precursor-like protein 2 0.0234168
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.0233623
ISG15 ISG15 ubiquitin-like modifier 0.023334
EIF4B eukaryotic translation initiation factor 4B 0.0232088
CALR calreticulin 0.0230754
SRSF11 serine/arginine-rich splicing factor 11 0.0225169
RABGAP1 RAB GTPase activating protein 1 0.0213951
STC1 stanniocalcin 1 0.0213355
MACF1 microtubule-actin crosslinking factor 1 0.0213319
SET SET nuclear proto-oncogene 0.0209409
SMC1A structural maintenance of chromosomes 1A 0.020928
NFE2L1 nuclear factor, erythroid 2-like 1 0.0209128
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0209025
RPL4 ribosomal protein L4 0.0207296
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.0202797
EFNA5 ephrin-A5 0.0199913
DST dystonin 0.0198636
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.0197393
WDR26 WD repeat domain 26 0.0196385
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0192011
EEF2 eukaryotic translation elongation factor 2 0.0191531
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.0191103
CEMIP cell migration inducing protein, hyaluronan binding 0.0190991
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.018999
RNF144A ring finger protein 144A 0.0188323
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0185863
GPAT4 glycerol-3-phosphate acyltransferase 4 0.018556
SLC39A11 solute carrier family 39, member 11 0.0184945
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.0184103
ST18 suppression of tumorigenicity 18, zinc finger 0.0182363
LRP5 low density lipoprotein receptor-related protein 5 0.0176711
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2 0.0175514
PHF8 PHD finger protein 8 0.017482
ATF4 activating transcription factor 4 0.0173159
AKAP9 A kinase (PRKA) anchor protein 9 0.0172262
UBE3A ubiquitin protein ligase E3A 0.0171993
GTPBP4 GTP binding protein 4 0.0171989
GRK5 G protein-coupled receptor kinase 5 0.0171823
MSN moesin 0.0171704
DUSP4 dual specificity phosphatase 4 0.0171495
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0170237
DOCK5 dedicator of cytokinesis 5 0.0170145
SFPQ splicing factor proline/glutamine-rich 0.0168589
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.0167145
SRRM2 serine/arginine repetitive matrix 2 0.0165423
TSPYL2 TSPY-like 2 0.01654
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0163191
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.0162779
AKAP12 A kinase (PRKA) anchor protein 12 0.0160361
RSAD2 radical S-adenosyl methionine domain containing 2 0.0160026
SCG3 secretogranin III 0.0159933
MAN1A2 mannosidase, alpha, class 1A, member 2 0.015984
SYT13 synaptotagmin XIII 0.0159045
HDGF hepatoma-derived growth factor 0.0159037

decreased expression

Symbol Name Standardized Value
GPC6 glypican 6 -0.168257
TENM1 teneurin transmembrane protein 1 -0.152183
NALF1 NALCN channel auxiliary factor 1 -0.111283
SNTG1 syntrophin, gamma 1 -0.0868017
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -0.086215
PTMA prothymosin, alpha -0.0816783
DTNA dystrobrevin, alpha -0.0812563
NKAIN2 Na+/K+ transporting ATPase interacting 2 -0.0806919
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0744193
PEG10 paternally expressed 10 -0.0735831
RORA RAR-related orphan receptor A -0.0671556
ADGRL2 adhesion G protein-coupled receptor L2 -0.0660137
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0657802
CENPF centromere protein F, 350/400kDa -0.063022
SYT1 synaptotagmin I -0.0620419
TRIO trio Rho guanine nucleotide exchange factor -0.0612053
MAP1B microtubule-associated protein 1B -0.0609151
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0604155
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.0560462
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0517497
CAMK1D calcium/calmodulin-dependent protein kinase ID -0.0496432
PTCHD4 patched domain containing 4 -0.047577
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0455221
NIPBL Nipped-B homolog (Drosophila) -0.0450237
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0447022
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.0446205
RIMS2 regulating synaptic membrane exocytosis 2 -0.0441889
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0440761
CA8 carbonic anhydrase VIII -0.0439744
TRA2A transformer 2 alpha homolog (Drosophila) -0.0435768
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0433689
CNKSR3 CNKSR family member 3 -0.0432031
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0429236
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 -0.0426471
SMC4 structural maintenance of chromosomes 4 -0.0425541
RERE arginine-glutamic acid dipeptide (RE) repeats -0.0423476
ZNF804A zinc finger protein 804A -0.0418377
CALCA calcitonin-related polypeptide alpha -0.0416853
KLHL29 kelch-like family member 29 -0.0415152
NFIA nuclear factor I/A -0.0401422
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0397669
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0396079
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.0392311
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.039004
NCOR1 nuclear receptor corepressor 1 -0.0388548
EGR1 early growth response 1 -0.038741
TPD52 tumor protein D52 -0.0385729
G2E3 G2/M-phase specific E3 ubiquitin protein ligase -0.0382791
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0380742
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0379387
ZNF292 zinc finger protein 292 -0.0378566
CADM1 cell adhesion molecule 1 -0.0368622
ATF6 activating transcription factor 6 -0.0367252
DENND4A DENN/MADD domain containing 4A -0.0366565
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.0361954
AGMO alkylglycerol monooxygenase -0.035754
CDK13 cyclin-dependent kinase 13 -0.035736
JAM3 junctional adhesion molecule 3 -0.0355369
MBNL2 muscleblind-like splicing regulator 2 -0.0354998
ESRRG estrogen-related receptor gamma -0.0352105
FUS FUS RNA binding protein -0.0351564
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0350517
TPR translocated promoter region, nuclear basket protein -0.0346656
SSBP2 single-stranded DNA binding protein 2 -0.0342632
NAP1L1 nucleosome assembly protein 1-like 1 -0.0341807
GPC5 glypican 5 -0.0337662
GNAS GNAS complex locus -0.0337335
DGKB diacylglycerol kinase, beta 90kDa -0.0333432
HDAC9 histone deacetylase 9 -0.0329908
DENND1A DENN/MADD domain containing 1A -0.0325621
SENP6 SUMO1/sentrin specific peptidase 6 -0.0321352
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0320807
FOXC1 forkhead box C1 -0.0318054
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.0312961
APP amyloid beta (A4) precursor protein -0.031092
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -0.0310905
TSHZ2 teashirt zinc finger homeobox 2 -0.0304932
GRB10 growth factor receptor-bound protein 10 -0.0302753
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.0299506
GLCCI1 glucocorticoid induced 1 -0.029494
FHIT fragile histidine triad -0.0292277
ALCAM activated leukocyte cell adhesion molecule -0.0290209
GAS2L3 growth arrest-specific 2 like 3 -0.0289199
FGF14 fibroblast growth factor 14 -0.0288952
ERO1B endoplasmic reticulum oxidoreductase 1 beta -0.0287054
RAD21 RAD21 homolog (S. pombe) -0.0286922
CDH12 cadherin 12, type 2 (N-cadherin 2) -0.0282865
SINHCAF SIN3-HDAC complex associated factor -0.0280558
JARID2 jumonji, AT rich interactive domain 2 -0.0279548
MARCHF6 membrane associated ring-CH-type finger 6 -0.0279497
TENT5A terminal nucleotidyltransferase 5A -0.027906
MARK3 MAP/microtubule affinity-regulating kinase 3 -0.0277944
FOXO3 forkhead box O3 -0.0275324
EMSY EMSY transcriptional repressor, BRCA2 interacting -0.0272565
KCTD8 potassium channel tetramerization domain containing 8 -0.0272042
HOMER1 homer scaffolding protein 1 -0.0271061
CYRIB CYFIP related Rac1 interactor B -0.0269671
ANKRD17 ankyrin repeat domain 17 -0.0269566
SEPTIN7 septin 7 -0.0267655
EXOC4 exocyst complex component 4 -0.0267246