Gallic acid_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PDE4D phosphodiesterase 4D, cAMP-specific 0.114541
PKM pyruvate kinase, muscle 0.107077
AHNAK AHNAK nucleoprotein 0.104327
EGFR epidermal growth factor receptor 0.0812454
PDGFC platelet derived growth factor C 0.0649699
RPL3 ribosomal protein L3 0.0622851
POTEF POTE ankyrin domain family, member F 0.0605642
ENO1 enolase 1, (alpha) 0.0554515
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0554469
B2M beta-2-microglobulin 0.0504167
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0489119
DSCAM Down syndrome cell adhesion molecule 0.0486471
TXNRD1 thioredoxin reductase 1 0.0480435
TBC1D5 TBC1 domain family, member 5 0.0412326
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0410508
DUSP4 dual specificity phosphatase 4 0.0406609
TMSB4X thymosin beta 4, X-linked 0.0404455
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0399506
ADAM10 ADAM metallopeptidase domain 10 0.0399027
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0382031
PCBP2 poly(rC) binding protein 2 0.0380006
VMP1 vacuole membrane protein 1 0.0368805
PYGB phosphorylase, glycogen; brain 0.0367507
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0359339
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.0313612
EIF4B eukaryotic translation initiation factor 4B 0.0306554
ZBTB20 zinc finger and BTB domain containing 20 0.0305174
LDHA lactate dehydrogenase A 0.0302846
EEF2 eukaryotic translation elongation factor 2 0.0293693
PLK2 polo-like kinase 2 0.0285492
VCL vinculin 0.0280721
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0278126
UHMK1 U2AF homology motif (UHM) kinase 1 0.0275314
PITPNB phosphatidylinositol transfer protein, beta 0.027152
ACTG1 actin gamma 1 0.0269994
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0269464
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0266757
ZFAND3 zinc finger, AN1-type domain 3 0.0261715
EZR ezrin 0.0257836
TMEM65 transmembrane protein 65 0.0249362
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.024104
RPL4 ribosomal protein L4 0.0240915
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0238097
RAD21 RAD21 homolog (S. pombe) 0.0236899
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0235254
BCAS3 breast carcinoma amplified sequence 3 0.0234614
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0231033
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0230957
RIGI RNA sensor RIG-I 0.0229603
SQSTM1 sequestosome 1 0.0227774
BBS9 Bardet-Biedl syndrome 9 0.022714
NBAS neuroblastoma amplified sequence 0.0225897
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 0.0225281
ENO2 enolase 2 (gamma, neuronal) 0.022483
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0219124
MED13L mediator complex subunit 13-like 0.0211133
ADAR adenosine deaminase, RNA-specific 0.0208469
PICALM phosphatidylinositol binding clathrin assembly protein 0.0207169
ADAM9 ADAM metallopeptidase domain 9 0.020661
LOXL3 lysyl oxidase-like 3 0.0206451
FAM13B family with sequence similarity 13, member B 0.0198627
ITSN2 intersectin 2 0.0198207
TRAPPC9 trafficking protein particle complex 9 0.019705
AK2 adenylate kinase 2 0.0196374
HIPK3 homeodomain interacting protein kinase 3 0.0196328
OLA1 Obg-like ATPase 1 0.0195643
STAG2 stromal antigen 2 0.0194207
TNIP1 TNFAIP3 interacting protein 1 0.0192955
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0192935
ASPH aspartate beta-hydroxylase 0.0192398
ANK2 ankyrin 2, neuronal 0.019214
RPS18 ribosomal protein S18 0.0190115
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.0190108
ZZZ3 zinc finger, ZZ-type containing 3 0.0189752
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0189132
CEP250 centrosomal protein 250kDa 0.0186843
NQO1 NAD(P)H dehydrogenase, quinone 1 0.0186485
TPM3 tropomyosin 3 0.0185282
ARL15 ADP-ribosylation factor-like 15 0.0184998
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0184888
GDAP2 ganglioside induced differentiation associated protein 2 0.0183596
GARS1 glycyl-tRNA synthetase 1 0.0181265
METTL15 methyltransferase like 15 0.0180594
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.0177793
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.0177709
ELOVL5 ELOVL fatty acid elongase 5 0.0174363
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.0171676
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0169545
ATP9B ATPase, class II, type 9B 0.0168655
FBXO7 F-box protein 7 0.0167621
SRSF4 serine/arginine-rich splicing factor 4 0.0166996
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.0166617
PAQR3 progestin and adipoQ receptor family member III 0.0166154
MIER1 mesoderm induction early response 1, transcriptional regulator 0.0165503
NFE2L1 nuclear factor, erythroid 2-like 1 0.0165139
APLP2 amyloid beta (A4) precursor-like protein 2 0.0164405
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.0164238
EHBP1L1 EH domain binding protein 1-like 1 0.0164192
DAND5 DAN domain family member 5, BMP antagonist 0.0162529
URI1 URI1, prefoldin-like chaperone 0.0161973

decreased expression

Symbol Name Standardized Value
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.200696
PDE4B phosphodiesterase 4B, cAMP-specific -0.191201
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.143492
CPED1 cadherin-like and PC-esterase domain containing 1 -0.110206
PTMA prothymosin, alpha -0.108899
BMP10 bone morphogenetic protein 10 -0.106831
TPT1 tumor protein, translationally-controlled 1 -0.106059
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0901657
RPL35A ribosomal protein L35a -0.0884915
RPS6 ribosomal protein S6 -0.0861494
SSBP2 single-stranded DNA binding protein 2 -0.0836698
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0816604
FOXP1 forkhead box P1 -0.0813202
CAMKMT calmodulin-lysine N-methyltransferase -0.0758542
CCND1 cyclin D1 -0.0684014
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.066369
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0561834
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0542754
NAP1L1 nucleosome assembly protein 1-like 1 -0.0519076
RPS8 ribosomal protein S8 -0.0511201
EFNA5 ephrin-A5 -0.0490102
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0489054
GLI2 GLI family zinc finger 2 -0.0480643
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0460221
KPNB1 karyopherin (importin) beta 1 -0.0450253
GNAS GNAS complex locus -0.0447842
CUX1 cut-like homeobox 1 -0.0441139
DLG1 discs, large homolog 1 (Drosophila) -0.0437592
NFIA nuclear factor I/A -0.0434065
MKI67 marker of proliferation Ki-67 -0.0422842
RPL19 ribosomal protein L19 -0.0422067
WSB1 WD repeat and SOCS box containing 1 -0.0420556
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0413772
MYOF myoferlin -0.0404909
RPL9 ribosomal protein L9 -0.0396906
RPS24 ribosomal protein S24 -0.0392922
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0392613
HSPB1 heat shock 27kDa protein 1 -0.0390465
RPLP2 ribosomal protein, large, P2 -0.038705
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0386955
RRBP1 ribosome binding protein 1 -0.038672
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0383713
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0366379
BCOR BCL6 corepressor -0.0363241
GPHN gephyrin -0.0362161
MYL12B myosin, light chain 12B, regulatory -0.0360972
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0356063
NPAS2 neuronal PAS domain protein 2 -0.0353207
TRIO trio Rho guanine nucleotide exchange factor -0.0352266
NEBL nebulette -0.035155
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0346758
RPL34 ribosomal protein L34 -0.0344593
ASCC3 activating signal cointegrator 1 complex subunit 3 -0.0341623
GLI3 GLI family zinc finger 3 -0.033359
RPL11 ribosomal protein L11 -0.0328544
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -0.0327323
TJP1 tight junction protein 1 -0.0316123
IARS1 isoleucyl-tRNA synthetase 1 -0.0314808
SMC4 structural maintenance of chromosomes 4 -0.0314672
NIPBL Nipped-B homolog (Drosophila) -0.0312652
ZNF438 zinc finger protein 438 -0.0312211
NAV2 neuron navigator 2 -0.0310157
NT5C2 5'-nucleotidase, cytosolic II -0.0309938
FBXO11 F-box protein 11 -0.0306736
RPLP1 ribosomal protein, large, P1 -0.0305063
RPL31 ribosomal protein L31 -0.0303767
RPS19 ribosomal protein S19 -0.0300053
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0298946
RPL38 ribosomal protein L38 -0.0297995
PATJ PATJ crumbs cell polarity complex component -0.0297209
RAB7A RAB7A, member RAS oncogene family -0.0297074
TRERF1 transcriptional regulating factor 1 -0.0294483
ITSN1 intersectin 1 (SH3 domain protein) -0.0291446
MSI2 musashi RNA-binding protein 2 -0.0291435
DPYD dihydropyrimidine dehydrogenase -0.0289545
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0289268
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0283549
ARL4C ADP-ribosylation factor-like 4C -0.0281787
BMP2K BMP2 inducible kinase -0.0281569
PDIA3 protein disulfide isomerase family A, member 3 -0.0278065
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.027706
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0275091
RPL5 ribosomal protein L5 -0.0273541
RPL27A ribosomal protein L27a -0.0272671
MON2 MON2 homolog (S. cerevisiae) -0.0271109
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0269993
INTS6 integrator complex subunit 6 -0.0268228
EVI5 ecotropic viral integration site 5 -0.0267387
FLNB filamin B, beta -0.0267269
DOCK1 dedicator of cytokinesis 1 -0.026683
RPS11 ribosomal protein S11 -0.026673
UNC13A unc-13 homolog A (C. elegans) -0.0265367
CREB5 cAMP responsive element binding protein 5 -0.0264167
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0262339
ZNF609 zinc finger protein 609 -0.0261498
CCNH cyclin H -0.0259344
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0258747
SBF2 SET binding factor 2 -0.0258659
RPL8 ribosomal protein L8 -0.025594
PDE7B phosphodiesterase 7B -0.0255409