Gallic acid_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SNU-423 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
COL6A3 collagen, type VI, alpha 3 0.152853
AKAP12 A kinase (PRKA) anchor protein 12 0.104991
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.103344
VEGFA vascular endothelial growth factor A 0.0902988
MYH9 myosin, heavy chain 9, non-muscle 0.0880577
MSN moesin 0.0724129
GLIS3 GLIS family zinc finger 3 0.0686741
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0671429
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0643454
HDAC9 histone deacetylase 9 0.0630883
VCAN versican 0.0572848
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.0529428
APLP2 amyloid beta (A4) precursor-like protein 2 0.052337
AHNAK AHNAK nucleoprotein 0.0516226
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0514908
EEF2 eukaryotic translation elongation factor 2 0.0514472
DST dystonin 0.0497573
COL5A1 collagen, type V, alpha 1 0.0487722
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0474829
UGCG UDP-glucose ceramide glucosyltransferase 0.0462835
PCBP2 poly(rC) binding protein 2 0.0460246
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0451647
ASPH aspartate beta-hydroxylase 0.0446974
MCL1 myeloid cell leukemia 1 0.0433801
FRMD4A FERM domain containing 4A 0.0431841
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0413168
FMNL2 formin-like 2 0.0408418
MACF1 microtubule-actin crosslinking factor 1 0.0399913
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0393999
UBA6 ubiquitin-like modifier activating enzyme 6 0.0382288
SEPTIN9 septin 9 0.0372606
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0365128
VMP1 vacuole membrane protein 1 0.0362212
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0361306
USP9X ubiquitin specific peptidase 9, X-linked 0.0351093
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0350995
RPL3 ribosomal protein L3 0.0348791
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0347491
PLIN2 perilipin 2 0.0342636
ENO1 enolase 1, (alpha) 0.0340541
ZSWIM6 zinc finger, SWIM-type containing 6 0.0335077
CCNL1 cyclin L1 0.0329975
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0327321
MLPH melanophilin 0.0319593
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.031702
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0315918
HMGA2 high mobility group AT-hook 2 0.0313569
FLNB filamin B, beta 0.0306416
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0304982
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0303751
TIMP2 TIMP metallopeptidase inhibitor 2 0.0291012
POTEF POTE ankyrin domain family, member F 0.0278078
EPAS1 endothelial PAS domain protein 1 0.0277981
INTS6 integrator complex subunit 6 0.0275025
EIF4B eukaryotic translation initiation factor 4B 0.0269832
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0267848
MYOF myoferlin 0.0267465
EFNA5 ephrin-A5 0.0258952
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0256571
MED13L mediator complex subunit 13-like 0.0255527
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0252956
MYO10 myosin X 0.0251037
AKAP13 A kinase (PRKA) anchor protein 13 0.0249677
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0249202
SFPQ splicing factor proline/glutamine-rich 0.0248584
WWTR1 WW domain containing transcription regulator 1 0.0246081
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.0244767
GPC6 glypican 6 0.0242255
BRD2 bromodomain containing 2 0.0241065
TNS3 tensin 3 0.0240124
SVIL supervillin 0.0239428
IRAK2 interleukin-1 receptor-associated kinase 2 0.0239038
TGM2 transglutaminase 2 0.0238063
BCL9L B-cell CLL/lymphoma 9-like 0.0235505
TXNIP thioredoxin interacting protein 0.0230643
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0230112
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.0224361
TNIK TRAF2 and NCK interacting kinase 0.0222529
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0219863
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0217954
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0217266
DUSP10 dual specificity phosphatase 10 0.0217225
AHR aryl hydrocarbon receptor 0.0216642
ENO2 enolase 2 (gamma, neuronal) 0.0216391
ATP13A3 ATPase type 13A3 0.0213052
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0210164
YAP1 Yes-associated protein 1 0.020939
TENT5A terminal nucleotidyltransferase 5A 0.0208811
C3 complement component 3 0.0206915
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0206815
SOX9 SRY (sex determining region Y)-box 9 0.0206486
EGFR epidermal growth factor receptor 0.0204488
WDR27 WD repeat domain 27 0.0202964
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.020242
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0200501
F2R coagulation factor II (thrombin) receptor 0.0200035
UBASH3B ubiquitin associated and SH3 domain containing B 0.019936
NFE2L1 nuclear factor, erythroid 2-like 1 0.0199139
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.0199134
TMEM132D transmembrane protein 132D 0.0199008

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.191587
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.135883
TPT1 tumor protein, translationally-controlled 1 -0.111449
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.110155
HLA-B major histocompatibility complex, class I, B -0.108518
IER3 immediate early response 3 -0.108048
FN1 fibronectin 1 -0.0904628
RPS24 ribosomal protein S24 -0.0762488
NAMPT nicotinamide phosphoribosyltransferase -0.0692855
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0657781
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0651494
TRIO trio Rho guanine nucleotide exchange factor -0.0642157
MKI67 marker of proliferation Ki-67 -0.0627638
SOD2 superoxide dismutase 2, mitochondrial -0.0610193
KDM3A lysine (K)-specific demethylase 3A -0.0606856
GNAS GNAS complex locus -0.0590842
HLA-E major histocompatibility complex, class I, E -0.0585486
TMSB10 thymosin beta 10 -0.0581378
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0545978
TPM4 tropomyosin 4 -0.0525843
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -0.0524191
RPL35A ribosomal protein L35a -0.0509575
CENPF centromere protein F, 350/400kDa -0.0508187
ANLN anillin, actin binding protein -0.050397
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0490641
ZMYND8 zinc finger, MYND-type containing 8 -0.0483619
PGK1 phosphoglycerate kinase 1 -0.0483122
RPS6 ribosomal protein S6 -0.0471514
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0470298
SMC4 structural maintenance of chromosomes 4 -0.0470005
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0460347
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.0460344
TUBB tubulin, beta class I -0.0460118
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0458914
RBM39 RNA binding motif protein 39 -0.0442223
RB1CC1 RB1-inducible coiled-coil 1 -0.0436647
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0428698
KIF4A kinesin family member 4A -0.042385
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0417796
RTN4 reticulon 4 -0.0410695
RRBP1 ribosome binding protein 1 -0.0405729
DEK DEK proto-oncogene -0.0404564
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0404093
WSB1 WD repeat and SOCS box containing 1 -0.0393254
RPL26 ribosomal protein L26 -0.0387113
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0380656
SDCBP syndecan binding protein (syntenin) -0.0375238
OSMR oncostatin M receptor -0.0375063
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.036454
KLF6 Kruppel-like factor 6 -0.0364367
MORF4L2 mortality factor 4 like 2 -0.0361088
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0358094
SLC38A1 solute carrier family 38, member 1 -0.0357681
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0354248
PTMA prothymosin, alpha -0.0342414
RPL36A ribosomal protein L36a -0.0339844
NCOA7 nuclear receptor coactivator 7 -0.0332857
ZFAND3 zinc finger, AN1-type domain 3 -0.0328981
GAS2L3 growth arrest-specific 2 like 3 -0.0328767
RPL34 ribosomal protein L34 -0.0328238
LCORL ligand dependent nuclear receptor corepressor-like -0.0328046
HDLBP high density lipoprotein binding protein -0.0327612
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -0.0327533
RPLP1 ribosomal protein, large, P1 -0.0326349
SRGN serglycin -0.032266
TPX2 TPX2, microtubule-associated -0.0322419
IFI16 interferon, gamma-inducible protein 16 -0.0321812
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0320535
MXI1 MAX interactor 1, dimerization protein -0.031871
RPS8 ribosomal protein S8 -0.031858
CDCP1 CUB domain containing protein 1 -0.0315969
RAD21 RAD21 homolog (S. pombe) -0.0315865
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0313316
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0312141
HLA-C major histocompatibility complex, class I, C -0.0309594
SPAG9 sperm associated antigen 9 -0.0306706
LOC112694756 uncharaterized LOC112694756 -0.030655
BTG1 B-cell translocation gene 1, anti-proliferative -0.0302077
KPNB1 karyopherin (importin) beta 1 -0.029997
VDAC1 voltage-dependent anion channel 1 -0.0297081
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0294876
ARF1 ADP-ribosylation factor 1 -0.0294529
PRR11 proline rich 11 -0.0293151
EIF1 eukaryotic translation initiation factor 1 -0.0289136
RPLP0 ribosomal protein, large, P0 -0.0284972
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0283641
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0283298
CANX calnexin -0.0280381
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0280188
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.0277116
RPL19 ribosomal protein L19 -0.0270656
CEP95 centrosomal protein 95kDa -0.0269916
RPL11 ribosomal protein L11 -0.0269189
RPL32 ribosomal protein L32 -0.0266758
RPL38 ribosomal protein L38 -0.0266204
UBE2I ubiquitin-conjugating enzyme E2I -0.0264738
TMEM263 transmembrane protein 263 -0.0263869
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0260387
MAP4 microtubule-associated protein 4 -0.0259189
CAVIN1 caveolae associated protein 1 -0.0259078