Gallic acid_SW 1088 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SW 1088 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.159763
FN1 fibronectin 1 0.154804
MYH9 myosin, heavy chain 9, non-muscle 0.149019
ERRFI1 ERBB receptor feedback inhibitor 1 0.146643
COL6A3 collagen, type VI, alpha 3 0.133504
PRELID2 PRELI domain containing 2 0.107407
CD44 CD44 molecule (Indian blood group) 0.0938893
COL5A1 collagen, type V, alpha 1 0.0860486
ENO1 enolase 1, (alpha) 0.0839467
HIP1 huntingtin interacting protein 1 0.0827434
FNDC3B fibronectin type III domain containing 3B 0.0787243
HMGA2 high mobility group AT-hook 2 0.0731186
MACF1 microtubule-actin crosslinking factor 1 0.0679097
KYNU kynureninase 0.0657989
AKAP12 A kinase (PRKA) anchor protein 12 0.0598669
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0598174
COL7A1 collagen, type VII, alpha 1 0.0563628
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0563096
VIM vimentin 0.055643
ANXA2 annexin A2 0.0556337
GLIS3 GLIS family zinc finger 3 0.0536812
FAM20C family with sequence similarity 20, member C 0.0528538
MYOF myoferlin 0.0518091
ALK anaplastic lymphoma receptor tyrosine kinase 0.0511235
HIPK2 homeodomain interacting protein kinase 2 0.0504392
ASPH aspartate beta-hydroxylase 0.0504301
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.0501292
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0500726
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0479866
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0478895
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0474497
OGA O-GlcNAcase 0.0473497
GSE1 Gse1 coiled-coil protein 0.0471029
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0443679
TIMP3 TIMP metallopeptidase inhibitor 3 0.0443138
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0441407
RUNX1 runt-related transcription factor 1 0.0428222
FLNA filamin A, alpha 0.0413587
MCL1 myeloid cell leukemia 1 0.0412367
ABLIM3 actin binding LIM protein family, member 3 0.0409832
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0400389
THBS1 thrombospondin 1 0.039768
IGFBP5 insulin-like growth factor binding protein 5 0.0395395
VEGFC vascular endothelial growth factor C 0.0395328
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.039274
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0390407
DNAH11 dynein, axonemal, heavy chain 11 0.038606
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.0380309
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.03769
NRXN3 neurexin 3 0.0376393
SHB Src homology 2 domain containing adaptor protein B 0.0373502
EXT1 exostosin glycosyltransferase 1 0.0372123
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0360726
TOP1 topoisomerase (DNA) I 0.0360159
NAV1 neuron navigator 1 0.0359241
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0357227
PTK2 protein tyrosine kinase 2 0.0357226
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0353426
PRSS23 protease, serine, 23 0.0347563
FBXL7 F-box and leucine-rich repeat protein 7 0.0347071
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0346863
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.033975
KMT2C lysine (K)-specific methyltransferase 2C 0.0337994
PTPRM protein tyrosine phosphatase, receptor type, M 0.0323504
TNS3 tensin 3 0.0318394
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0313998
TRIO trio Rho guanine nucleotide exchange factor 0.031394
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0309441
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0308504
NIBAN2 niban apoptosis regulator 2 0.0303441
PLEC plectin 0.030224
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0299375
SDC4 syndecan 4 0.0295986
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.028639
TPM3 tropomyosin 3 0.0284371
INTS6 integrator complex subunit 6 0.028413
TNIP1 TNFAIP3 interacting protein 1 0.0282803
ARID5B AT rich interactive domain 5B (MRF1-like) 0.0282719
ITGAV integrin, alpha V 0.0276929
EGFR epidermal growth factor receptor 0.027648
ATXN1 ataxin 1 0.0269828
FAM13A family with sequence similarity 13, member A 0.0269583
CLIP2 CAP-GLY domain containing linker protein 2 0.0269473
ACTN4 actinin, alpha 4 0.0269359
NFE2L1 nuclear factor, erythroid 2-like 1 0.0269198
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0265984
TRIOBP TRIO and F-actin binding protein 0.026515
HSPA8 heat shock 70kDa protein 8 0.0261822
MTERF1 mitochondrial transcription termination factor 1 0.026131
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0260254
ZNF608 zinc finger protein 608 0.0260097
MYO10 myosin X 0.0255911
DST dystonin 0.0252434
ANXA5 annexin A5 0.0249304
RPL3 ribosomal protein L3 0.0248329
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0246362
TMSB4X thymosin beta 4, X-linked 0.0246013
ANKRD12 ankyrin repeat domain 12 0.0245282
MRTFA myocardin related transcription factor A 0.0244806
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0244136

decreased expression

Symbol Name Standardized Value
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.202397
COL1A2 collagen, type I, alpha 2 -0.135553
COL1A1 collagen, type I, alpha 1 -0.124021
IGFBP3 insulin-like growth factor binding protein 3 -0.115679
LOX lysyl oxidase -0.0723163
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0713678
HLA-B major histocompatibility complex, class I, B -0.0624833
TGFBI transforming growth factor, beta-induced, 68kDa -0.0608418
HLA-C major histocompatibility complex, class I, C -0.0563618
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0528165
PDIA3 protein disulfide isomerase family A, member 3 -0.0520917
COL6A1 collagen, type VI, alpha 1 -0.051651
GOLGA4 golgin A4 -0.0503243
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.0483985
B2M beta-2-microglobulin -0.047486
EGR1 early growth response 1 -0.0462129
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.045988
COL5A2 collagen, type V, alpha 2 -0.045242
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0442271
FTL ferritin, light polypeptide -0.0438156
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0425759
CALU calumenin -0.0425692
CCNI cyclin I -0.0415091
NDRG1 N-myc downstream regulated 1 -0.0409603
TMSB10 thymosin beta 10 -0.0403883
TTC3 tetratricopeptide repeat domain 3 -0.0401317
HLA-A major histocompatibility complex, class I, A -0.0399889
SLC38A2 solute carrier family 38, member 2 -0.0384952
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0377274
NOP58 NOP58 ribonucleoprotein -0.0358071
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0349086
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0348121
LMAN1 lectin, mannose-binding, 1 -0.0341394
PLCB4 phospholipase C, beta 4 -0.0331236
STC1 stanniocalcin 1 -0.0329856
VDAC1 voltage-dependent anion channel 1 -0.0329543
MMP14 matrix metallopeptidase 14 (membrane-inserted) -0.0319769
CDK6 cyclin-dependent kinase 6 -0.0319664
H3-3B H3.3 histone B -0.0313372
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 -0.0301382
TUBA1B tubulin, alpha 1b -0.0301349
GARS1 glycyl-tRNA synthetase 1 -0.0298267
RAB1A RAB1A, member RAS oncogene family -0.0296555
CD99 CD99 molecule -0.0284903
IGFBP7 insulin-like growth factor binding protein 7 -0.0284397
CTSD cathepsin D -0.0283638
PLAUR plasminogen activator, urokinase receptor -0.0279187
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0275989
DIAPH3 diaphanous-related formin 3 -0.0261371
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0259814
DLG1 discs, large homolog 1 (Drosophila) -0.0259545
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 -0.0257842
CENPF centromere protein F, 350/400kDa -0.0257355
COL3A1 collagen, type III, alpha 1 -0.0255887
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0254704
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0251644
GNAS GNAS complex locus -0.0249156
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0248796
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0242636
COPA coatomer protein complex, subunit alpha -0.0237985
THY1 Thy-1 cell surface antigen -0.0237596
TMEM41B transmembrane protein 41B -0.0234493
ITCH itchy E3 ubiquitin protein ligase -0.0234447
TMEM165 transmembrane protein 165 -0.0233846
PTN pleiotrophin -0.0232343
KMT2E lysine (K)-specific methyltransferase 2E -0.0230758
TMED9 transmembrane emp24 protein transport domain containing 9 -0.0229857
THOC2 THO complex 2 -0.0228306
IARS1 isoleucyl-tRNA synthetase 1 -0.0228078
HP1BP3 heterochromatin protein 1, binding protein 3 -0.0225505
HM13 histocompatibility (minor) 13 -0.022329
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0222461
CENPE centromere protein E, 312kDa -0.0221482
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.0220352
SCARB2 scavenger receptor class B, member 2 -0.0216879
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0216633
RLF rearranged L-myc fusion -0.0212352
CD109 CD109 molecule -0.0211013
RPL34 ribosomal protein L34 -0.0210898
S100A10 S100 calcium binding protein A10 -0.0209986
PRRC1 proline-rich coiled-coil 1 -0.020846
TPT1 tumor protein, translationally-controlled 1 -0.0207781
TMEM167A transmembrane protein 167A -0.0207126
NUSAP1 nucleolar and spindle associated protein 1 -0.0205822
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0205742
TNNC1 troponin C type 1 (slow) -0.0204558
MT2A metallothionein 2A -0.0204396
ACBD3 acyl-CoA binding domain containing 3 -0.0204212
RSAD2 radical S-adenosyl methionine domain containing 2 -0.020382
FUS FUS RNA binding protein -0.0203694
ZFHX3 zinc finger homeobox 3 -0.020364
FBN1 fibrillin 1 -0.0203189
RAB7A RAB7A, member RAS oncogene family -0.0202996
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0201441
OSBP oxysterol binding protein -0.0201148
MYADM myeloid-associated differentiation marker -0.0201059
NABP1 nucleic acid binding protein 1 -0.0199879
LAMB3 laminin, beta 3 -0.019953
MARCHF6 membrane associated ring-CH-type finger 6 -0.0198145
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 -0.0196543