Gallic acid_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SW 1271 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AHNAK AHNAK nucleoprotein 0.179287
SMAD3 SMAD family member 3 0.117313
ERRFI1 ERBB receptor feedback inhibitor 1 0.0975936
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0953841
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0899427
MACF1 microtubule-actin crosslinking factor 1 0.0883602
ENO1 enolase 1, (alpha) 0.0843407
BIRC3 baculoviral IAP repeat containing 3 0.0825479
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.080739
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0799968
DST dystonin 0.0774668
ANKRD28 ankyrin repeat domain 28 0.0773643
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0745517
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0738361
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0688487
ANGPTL4 angiopoietin-like 4 0.0610057
ELL2 elongation factor, RNA polymerase II, 2 0.0603008
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.059997
ASPH aspartate beta-hydroxylase 0.0588798
FMNL2 formin-like 2 0.0582915
MYH9 myosin, heavy chain 9, non-muscle 0.0567858
SMYD3 SET and MYND domain containing 3 0.0564217
FNDC3B fibronectin type III domain containing 3B 0.0541725
YAP1 Yes-associated protein 1 0.0524471
AKAP12 A kinase (PRKA) anchor protein 12 0.0517894
SH3KBP1 SH3-domain kinase binding protein 1 0.0517146
TXNIP thioredoxin interacting protein 0.0511628
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0510488
PKM pyruvate kinase, muscle 0.0476293
DGKD diacylglycerol kinase, delta 130kDa 0.0472625
FAM3C family with sequence similarity 3, member C 0.0468581
CEP250 centrosomal protein 250kDa 0.0462322
WWTR1 WW domain containing transcription regulator 1 0.0458851
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0454323
STK24 serine/threonine kinase 24 0.0451966
ANXA1 annexin A1 0.0445708
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0437982
CD44 CD44 molecule (Indian blood group) 0.0433667
NIBAN2 niban apoptosis regulator 2 0.0428485
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0417836
NAMPT nicotinamide phosphoribosyltransferase 0.0417185
POTEF POTE ankyrin domain family, member F 0.041325
ANO6 anoctamin 6 0.0404409
MCL1 myeloid cell leukemia 1 0.0400606
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0395716
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0395003
CAB39 calcium binding protein 39 0.0392652
RPL4 ribosomal protein L4 0.0390814
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0389904
EEF2 eukaryotic translation elongation factor 2 0.0388009
ADAM17 ADAM metallopeptidase domain 17 0.0379772
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0369583
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0365009
RPL23 ribosomal protein L23 0.0363769
KIF5B kinesin family member 5B 0.0356523
IRAK2 interleukin-1 receptor-associated kinase 2 0.0339002
PER1 period circadian clock 1 0.0338419
PDE4D phosphodiesterase 4D, cAMP-specific 0.03366
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0336228
SET SET nuclear proto-oncogene 0.0334545
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0332747
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0330643
SRRM2 serine/arginine repetitive matrix 2 0.0325105
TMEM245 transmembrane protein 245 0.0323698
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0320509
AHNAK2 AHNAK nucleoprotein 2 0.0320333
SVIL supervillin 0.0319612
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0317555
BCAR3 breast cancer anti-estrogen resistance 3 0.0316046
APLP2 amyloid beta (A4) precursor-like protein 2 0.0313845
APP amyloid beta (A4) precursor protein 0.031351
PCBP2 poly(rC) binding protein 2 0.0311352
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.0307127
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0302656
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0293359
USP34 ubiquitin specific peptidase 34 0.0292434
HSPA8 heat shock 70kDa protein 8 0.0292406
CHD1 chromodomain helicase DNA binding protein 1 0.0289542
EFNA5 ephrin-A5 0.0289119
TXNRD1 thioredoxin reductase 1 0.0286941
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0285329
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0282342
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0278945
JMJD1C jumonji domain containing 1C 0.0276324
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0269973
EIF4B eukaryotic translation initiation factor 4B 0.0268086
MSN moesin 0.0267992
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0266965
ITGB5 integrin, beta 5 0.0266873
AXL AXL receptor tyrosine kinase 0.0265584
DUSP12 dual specificity phosphatase 12 0.0265367
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0264757
TBL1X transducin (beta)-like 1X-linked 0.0263374
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0261582
ATP13A3 ATPase type 13A3 0.0261505
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0261484
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0259994
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0257088
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0256907
SPATS2 spermatogenesis associated, serine-rich 2 0.0256123

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.206362
TMSB10 thymosin beta 10 -0.123423
IGF2 insulin-like growth factor 2 -0.112679
TPT1 tumor protein, translationally-controlled 1 -0.104046
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0988617
PTMA prothymosin, alpha -0.0860372
VIM vimentin -0.0813759
IER3 immediate early response 3 -0.0669259
GNAS GNAS complex locus -0.0648049
HMGA2 high mobility group AT-hook 2 -0.0586533
VCL vinculin -0.0578617
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0546722
RPL35A ribosomal protein L35a -0.0541758
TM4SF1 transmembrane 4 L six family member 1 -0.0539305
EGR1 early growth response 1 -0.0531005
HILPDA hypoxia inducible lipid droplet-associated -0.0525664
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0520929
RIGI RNA sensor RIG-I -0.0477331
SPAG9 sperm associated antigen 9 -0.045399
FUS FUS RNA binding protein -0.0435616
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0428216
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0419682
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0411243
NF1 neurofibromin 1 -0.0409226
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0403022
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0402201
PNISR PNN-interacting serine/arginine-rich protein -0.0401418
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0393495
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0391452
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0382981
RAB2A RAB2A, member RAS oncogene family -0.03783
FNIP1 folliculin interacting protein 1 -0.0375272
PRSS23 protease, serine, 23 -0.037317
RPS13 ribosomal protein S13 -0.037128
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0370615
PODXL podocalyxin-like -0.0368942
INTS6 integrator complex subunit 6 -0.0366442
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -0.0361882
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.0360038
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0354509
NDRG1 N-myc downstream regulated 1 -0.0349955
WSB1 WD repeat and SOCS box containing 1 -0.0349216
PICALM phosphatidylinositol binding clathrin assembly protein -0.0349111
ADM adrenomedullin -0.0348845
CELF1 CUGBP, Elav-like family member 1 -0.0346115
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0345682
SQSTM1 sequestosome 1 -0.0328907
FNDC3A fibronectin type III domain containing 3A -0.0328411
CCDC138 coiled-coil domain containing 138 -0.0328057
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0327445
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0324641
NCOR1 nuclear receptor corepressor 1 -0.0324637
PFN1 profilin 1 -0.0324006
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0321941
GPC6 glypican 6 -0.0321545
BTG1 B-cell translocation gene 1, anti-proliferative -0.0318674
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0312554
MAP1B microtubule-associated protein 1B -0.0310994
HMGA1 high mobility group AT-hook 1 -0.0310203
AKAP10 A kinase (PRKA) anchor protein 10 -0.0308413
RTN4 reticulon 4 -0.0307526
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0307084
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.0302707
WARS1 tryptophanyl-tRNA synthetase 1 -0.0302055
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -0.0296118
COMMD10 COMM domain containing 10 -0.0295939
RNASEH2A ribonuclease H2, subunit A -0.0293336
H3-3B H3.3 histone B -0.0291179
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0290822
CANX calnexin -0.0288888
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0286016
HDLBP high density lipoprotein binding protein -0.0279465
IGFBP3 insulin-like growth factor binding protein 3 -0.0279122
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0276933
OSBPL8 oxysterol binding protein-like 8 -0.027438
TPM4 tropomyosin 4 -0.0274275
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0273013
PRR16 proline rich 16 -0.0268263
NPR2 natriuretic peptide receptor 2 -0.0266346
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0266141
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0264702
ZFAND3 zinc finger, AN1-type domain 3 -0.0263819
BPTF bromodomain PHD finger transcription factor -0.0262272
FLNB filamin B, beta -0.0261279
RPS6 ribosomal protein S6 -0.0261085
IGFBP4 insulin-like growth factor binding protein 4 -0.025947
B2M beta-2-microglobulin -0.0258298
USP53 ubiquitin specific peptidase 53 -0.0258188
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0258146
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0256749
FBXO11 F-box protein 11 -0.0255018
SLC38A2 solute carrier family 38, member 2 -0.0254618
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0253836
TAS2R14 taste receptor, type 2, member 14 -0.0253445
S100A10 S100 calcium binding protein A10 -0.025308
RPL26 ribosomal protein L26 -0.0252555
RPS14 ribosomal protein S14 -0.0249739
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0248501
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0248419
TRIM56 tripartite motif containing 56 -0.0246199