Gallic acid_SW 900 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SW 900 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ASPH aspartate beta-hydroxylase 0.213023
FN1 fibronectin 1 0.111288
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0866928
NRP1 neuropilin 1 0.0763887
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0720642
MYH9 myosin, heavy chain 9, non-muscle 0.069473
AHNAK AHNAK nucleoprotein 0.0630544
AHR aryl hydrocarbon receptor 0.0509337
APLP2 amyloid beta (A4) precursor-like protein 2 0.048021
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.0466468
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0443542
SEPTIN9 septin 9 0.0436378
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0419916
CAB39 calcium binding protein 39 0.0393199
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0383572
MCTP2 multiple C2 domains, transmembrane 2 0.0374348
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0372969
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0371916
APP amyloid beta (A4) precursor protein 0.0370385
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.036885
HSPA8 heat shock 70kDa protein 8 0.0368096
NRIP1 nuclear receptor interacting protein 1 0.0367329
TMEM156 transmembrane protein 156 0.0336674
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0334136
ANKRD28 ankyrin repeat domain 28 0.0331823
ENO1 enolase 1, (alpha) 0.0331348
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0329472
GLIS3 GLIS family zinc finger 3 0.0326909
DST dystonin 0.0322953
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.03206
RBMS1 RNA binding motif, single stranded interacting protein 1 0.0317672
PTK2 protein tyrosine kinase 2 0.0313463
SMAD3 SMAD family member 3 0.0308776
PCBP2 poly(rC) binding protein 2 0.0306658
IL6ST interleukin 6 signal transducer 0.0298389
OSMR oncostatin M receptor 0.029747
WWTR1 WW domain containing transcription regulator 1 0.0296729
EPS8 epidermal growth factor receptor pathway substrate 8 0.0295708
ELL2 elongation factor, RNA polymerase II, 2 0.0295701
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0295074
VCAN versican 0.0294556
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0293265
YAP1 Yes-associated protein 1 0.0291631
IFI44L interferon-induced protein 44-like 0.0286156
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0285878
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.0279596
TPM3 tropomyosin 3 0.0278658
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 0.0278141
PDE4D phosphodiesterase 4D, cAMP-specific 0.0275925
RUNX2 runt-related transcription factor 2 0.0275883
SPRED1 sprouty-related, EVH1 domain containing 1 0.0275625
MCL1 myeloid cell leukemia 1 0.0272498
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.0272359
ANKRD17 ankyrin repeat domain 17 0.027192
NPAS2 neuronal PAS domain protein 2 0.0266927
ITGAV integrin, alpha V 0.026566
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0265657
RNF145 ring finger protein 145 0.0263683
TXNIP thioredoxin interacting protein 0.0262284
ANXA2 annexin A2 0.0259887
RNF213 ring finger protein 213 0.0258976
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0256138
LTBP1 latent transforming growth factor beta binding protein 1 0.0256036
BICD1 bicaudal D homolog 1 (Drosophila) 0.0252201
ADAR adenosine deaminase, RNA-specific 0.0251019
MACF1 microtubule-actin crosslinking factor 1 0.0248999
BZW1 basic leucine zipper and W2 domains 1 0.0246071
RANBP2 RAN binding protein 2 0.0245298
LIFR leukemia inhibitory factor receptor alpha 0.0245042
FHL2 four and a half LIM domains 2 0.0244709
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.0240726
ZEB1 zinc finger E-box binding homeobox 1 0.0238749
CANX calnexin 0.0237838
SFTPA2 surfactant protein A2 0.0233728
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0233569
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0232879
TTC28 tetratricopeptide repeat domain 28 0.0231261
NTN4 netrin 4 0.023102
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.0230843
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0230449
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0225853
TLN1 talin 1 0.0224999
RDH10 retinol dehydrogenase 10 (all-trans) 0.0224283
ETNK1 ethanolamine kinase 1 0.0223251
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0222061
CALR calreticulin 0.022182
TOP1 topoisomerase (DNA) I 0.0221476
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0221191
N4BP2L2 NEDD4 binding protein 2-like 2 0.0219662
RPS3 ribosomal protein S3 0.0215176
NFE2L1 nuclear factor, erythroid 2-like 1 0.0214404
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.0210046
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0203998
SH3BP4 SH3-domain binding protein 4 0.020326
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0201481
AHNAK2 AHNAK nucleoprotein 2 0.0198593
ENO2 enolase 2 (gamma, neuronal) 0.0197883
EREG epiregulin 0.0196962
FAT1 FAT atypical cadherin 1 0.0196778
SVIL supervillin 0.0195673

decreased expression

Symbol Name Standardized Value
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.330303
NDRG1 N-myc downstream regulated 1 -0.145929
NRG1 neuregulin 1 -0.137254
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.133034
SQSTM1 sequestosome 1 -0.0998123
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0813362
TMSB10 thymosin beta 10 -0.0799101
STC2 stanniocalcin 2 -0.0787645
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0773326
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.076873
SOX4 SRY (sex determining region Y)-box 4 -0.0674748
LOC102724023 ES1 protein homolog, mitochondrial -0.0616316
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0601471
MRPS6 mitochondrial ribosomal protein S6 -0.0598499
IFI27 interferon, alpha-inducible protein 27 -0.0589988
FTL ferritin, light polypeptide -0.0589962
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.055612
S100A6 S100 calcium binding protein A6 -0.0551127
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0528257
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -0.0509358
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0471015
HLA-B major histocompatibility complex, class I, B -0.0459087
MT2A metallothionein 2A -0.0442917
TPT1 tumor protein, translationally-controlled 1 -0.0426092
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0425737
EFNA5 ephrin-A5 -0.0395463
HMGA2 high mobility group AT-hook 2 -0.0375107
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.037354
HMGA1 high mobility group AT-hook 1 -0.0353051
SPDYA speedy/RINGO cell cycle regulator family member A -0.0352031
ITGA1 integrin, alpha 1 -0.0347203
CTBP2 C-terminal binding protein 2 -0.034106
RAI14 retinoic acid induced 14 -0.0334517
BASP1 brain abundant, membrane attached signal protein 1 -0.0324059
LMNA lamin A/C -0.0324059
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0323749
TFPI2 tissue factor pathway inhibitor 2 -0.031832
SYT1 synaptotagmin I -0.031717
CADM1 cell adhesion molecule 1 -0.0316831
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.0310998
KDM5B lysine (K)-specific demethylase 5B -0.0310371
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0307536
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0306965
GRB10 growth factor receptor-bound protein 10 -0.0305569
WSB1 WD repeat and SOCS box containing 1 -0.0304961
SPAG9 sperm associated antigen 9 -0.0302801
IGFBP3 insulin-like growth factor binding protein 3 -0.029638
ESYT2 extended synaptotagmin-like protein 2 -0.0295055
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0293697
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0291462
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0291221
GNAS GNAS complex locus -0.028606
TMSB4X thymosin beta 4, X-linked -0.0280542
CALU calumenin -0.0277252
B2M beta-2-microglobulin -0.0267721
AHRR aryl-hydrocarbon receptor repressor -0.0266691
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -0.0265498
TRIO trio Rho guanine nucleotide exchange factor -0.0257062
TM4SF1 transmembrane 4 L six family member 1 -0.0254302
JUN jun proto-oncogene -0.0249444
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0246442
ATN1 atrophin 1 -0.0243701
RPL35A ribosomal protein L35a -0.0241034
RTN4 reticulon 4 -0.0237097
HLA-A major histocompatibility complex, class I, A -0.0236786
TRA2A transformer 2 alpha homolog (Drosophila) -0.0235614
PALLD palladin, cytoskeletal associated protein -0.0235355
RSF1 remodeling and spacing factor 1 -0.0234058
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.0228961
CTSD cathepsin D -0.0228885
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.0226981
TNS3 tensin 3 -0.02263
MON2 MON2 homolog (S. cerevisiae) -0.0224833
IER3 immediate early response 3 -0.022187
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0221215
TMEM263 transmembrane protein 263 -0.022097
PTMA prothymosin, alpha -0.022062
TNRC6C trinucleotide repeat containing 6C -0.0217845
VCL vinculin -0.0217435
BLZF1 basic leucine zipper nuclear factor 1 -0.0211995
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0211939
DUSP6 dual specificity phosphatase 6 -0.02091
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0208273
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0207773
RBM25 RNA binding motif protein 25 -0.020703
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0206224
EGR1 early growth response 1 -0.0205986
TMEM165 transmembrane protein 165 -0.0205869
SOX5 SRY (sex determining region Y)-box 5 -0.0205421
RAB7A RAB7A, member RAS oncogene family -0.0202132
FNIP1 folliculin interacting protein 1 -0.0201379
CPEB4 cytoplasmic polyadenylation element binding protein 4 -0.0200209
RPS21 ribosomal protein S21 -0.0200121
TAS2R14 taste receptor, type 2, member 14 -0.0198541
KLHL5 kelch-like family member 5 -0.0197494
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 -0.019743
RPL9 ribosomal protein L9 -0.0196427
HILPDA hypoxia inducible lipid droplet-associated -0.0196421
BTG1 B-cell translocation gene 1, anti-proliferative -0.0196263
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0194944