Gallic acid_SW1417 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Gallic acid perturbation in SW1417 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Gallic acid_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.111177
BCL2L1 BCL2-like 1 0.0969013
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0922479
FAT1 FAT atypical cadherin 1 0.0898543
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0823755
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0786323
EEF2 eukaryotic translation elongation factor 2 0.0724105
AHNAK AHNAK nucleoprotein 0.0659823
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.065488
DSPP dentin sialophosphoprotein 0.0644719
HSPA8 heat shock 70kDa protein 8 0.0633733
PCBP2 poly(rC) binding protein 2 0.0615944
RPL3 ribosomal protein L3 0.0611207
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0568065
MYH9 myosin, heavy chain 9, non-muscle 0.0538862
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0534284
RPS3 ribosomal protein S3 0.0531342
POTEF POTE ankyrin domain family, member F 0.0528301
RPS12 ribosomal protein S12 0.0524565
APLP2 amyloid beta (A4) precursor-like protein 2 0.0492316
FTH1 ferritin, heavy polypeptide 1 0.048164
MACC1 metastasis associated in colon cancer 1 0.0469155
LDHA lactate dehydrogenase A 0.0468448
SET SET nuclear proto-oncogene 0.046416
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0425018
EIF4B eukaryotic translation initiation factor 4B 0.0418928
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.0418905
OSBPL10 oxysterol binding protein-like 10 0.040914
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0407288
DIAPH1 diaphanous-related formin 1 0.0406174
ARHGAP42 Rho GTPase activating protein 42 0.0401993
ANXA11 annexin A11 0.038452
MACF1 microtubule-actin crosslinking factor 1 0.0383121
ENO1 enolase 1, (alpha) 0.0372769
ACTG1 actin gamma 1 0.0366587
TPM3 tropomyosin 3 0.0354857
BCL9L B-cell CLL/lymphoma 9-like 0.0349483
KMT2C lysine (K)-specific methyltransferase 2C 0.0348703
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0332825
RPS2 ribosomal protein S2 0.033154
RPL4 ribosomal protein L4 0.0330699
TXNIP thioredoxin interacting protein 0.0330275
DPY19L1 dpy-19-like 1 (C. elegans) 0.031067
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0310446
IPO7 importin 7 0.0305572
B2M beta-2-microglobulin 0.0303721
YAP1 Yes-associated protein 1 0.0297864
MCL1 myeloid cell leukemia 1 0.0295872
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.029488
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0292412
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0289057
USP9X ubiquitin specific peptidase 9, X-linked 0.0286824
PLEC plectin 0.0284592
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0281578
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0280626
ITGA6 integrin, alpha 6 0.0280167
CEMIP cell migration inducing protein, hyaluronan binding 0.0279669
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0278377
NEBL nebulette 0.0278062
TMF1 TATA element modulatory factor 1 0.0277617
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0275241
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0274448
BRD2 bromodomain containing 2 0.0272067
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0271522
CALR calreticulin 0.0270846
NFE2L1 nuclear factor, erythroid 2-like 1 0.0267765
KTN1 kinectin 1 (kinesin receptor) 0.0267048
RPL37A ribosomal protein L37a 0.0264796
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0264015
TMEM41B transmembrane protein 41B 0.0256556
MED13L mediator complex subunit 13-like 0.0251617
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0251516
MAN1A1 mannosidase, alpha, class 1A, member 1 0.0251035
FAM120A family with sequence similarity 120A 0.0246682
VMP1 vacuole membrane protein 1 0.0245266
SRRM2 serine/arginine repetitive matrix 2 0.0244988
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0244554
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.0244084
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0242818
USH1C Usher syndrome 1C (autosomal recessive, severe) 0.0242516
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3 0.0241714
GCLC glutamate-cysteine ligase, catalytic subunit 0.0239807
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.0239639
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0239265
FLNA filamin A, alpha 0.0237966
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0236316
GOLGB1 golgin B1 0.0235335
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0233738
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.0233386
VEGFA vascular endothelial growth factor A 0.023311
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0232634
ADAM19 ADAM metallopeptidase domain 19 0.0228265
CTNND1 catenin (cadherin-associated protein), delta 1 0.0227477
TXNRD1 thioredoxin reductase 1 0.0225329
NHSL1 NHS-like 1 0.0222142
HYOU1 hypoxia up-regulated 1 0.0219756
MYOF myoferlin 0.0219151
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 0.0219149
MKRN1 makorin ring finger protein 1 0.0217337
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0216902

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.0943022
H1-0 H1.0 linker histone -0.0893593
TMSB10 thymosin beta 10 -0.0827727
IER3 immediate early response 3 -0.076533
CCND1 cyclin D1 -0.075993
GNAS GNAS complex locus -0.0685238
RPS21 ribosomal protein S21 -0.0536716
TMEM123 transmembrane protein 123 -0.0508787
MAML2 mastermind-like 2 (Drosophila) -0.0507509
TPT1 tumor protein, translationally-controlled 1 -0.0498678
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.049531
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0493066
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0487514
KDM3A lysine (K)-specific demethylase 3A -0.0483049
FRMD5 FERM domain containing 5 -0.0477487
RPS24 ribosomal protein S24 -0.0456966
DLG1 discs, large homolog 1 (Drosophila) -0.0450154
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.042242
SLC38A1 solute carrier family 38, member 1 -0.0408954
EGR1 early growth response 1 -0.040042
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0397396
RPL35A ribosomal protein L35a -0.039013
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0369511
S100A10 S100 calcium binding protein A10 -0.0368841
WSB1 WD repeat and SOCS box containing 1 -0.0360108
STAU1 staufen double-stranded RNA binding protein 1 -0.0344661
GMDS GDP-mannose 4,6-dehydratase -0.0343525
ZMYND8 zinc finger, MYND-type containing 8 -0.034192
RBM39 RNA binding motif protein 39 -0.0341877
RPS6 ribosomal protein S6 -0.03153
RPL32 ribosomal protein L32 -0.0304421
RPL28 ribosomal protein L28 -0.0302284
FUS FUS RNA binding protein -0.0300649
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0299875
TRA2A transformer 2 alpha homolog (Drosophila) -0.029898
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0298941
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -0.0297673
NF1 neurofibromin 1 -0.0294332
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.029149
RAD21 RAD21 homolog (S. pombe) -0.0289308
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0286217
CTSD cathepsin D -0.0285617
HMGB1 high mobility group box 1 -0.0285505
RPL34 ribosomal protein L34 -0.0278998
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0276998
PERP PERP, TP53 apoptosis effector -0.0270412
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -0.026797
NDFIP1 Nedd4 family interacting protein 1 -0.0267447
SERINC5 serine incorporator 5 -0.0267055
HMGA1 high mobility group AT-hook 1 -0.0266407
ARHGAP12 Rho GTPase activating protein 12 -0.0265651
ANKHD1 ankyrin repeat and KH domain containing 1 -0.026228
RPL8 ribosomal protein L8 -0.0262053
THOC2 THO complex 2 -0.0259091
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0258314
PTPRK protein tyrosine phosphatase, receptor type, K -0.0255868
IFIH1 interferon induced with helicase C domain 1 -0.0254728
SLC38A2 solute carrier family 38, member 2 -0.0249157
EHBP1 EH domain binding protein 1 -0.0247409
H3-3B H3.3 histone B -0.0246114
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.0243667
CUX1 cut-like homeobox 1 -0.0243133
RAB7A RAB7A, member RAS oncogene family -0.0243033
NFIA nuclear factor I/A -0.023975
ZNFX1 zinc finger, NFX1-type containing 1 -0.0239593
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -0.0236797
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.023559
IARS1 isoleucyl-tRNA synthetase 1 -0.023542
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0230559
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0225149
LLGL2 lethal giant larvae homolog 2 (Drosophila) -0.0224871
RAB1A RAB1A, member RAS oncogene family -0.0223993
MAP4 microtubule-associated protein 4 -0.0222027
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 -0.022091
RPS5 ribosomal protein S5 -0.0219932
RHEB Ras homolog enriched in brain -0.0219871
OXSR1 oxidative stress responsive 1 -0.0219551
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0216986
PLSCR1 phospholipid scramblase 1 -0.021678
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0213806
SENP5 SUMO1/sentrin specific peptidase 5 -0.0213719
UBE2I ubiquitin-conjugating enzyme E2I -0.021238
SPAG9 sperm associated antigen 9 -0.0210112
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0208082
VDAC1 voltage-dependent anion channel 1 -0.0207253
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 -0.0207026
EMP1 epithelial membrane protein 1 -0.0206409
MX2 MX dynamin-like GTPase 2 -0.0205062
COBL cordon-bleu WH2 repeat protein -0.0204932
DEK DEK proto-oncogene -0.0204712
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0203287
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0200027
CD2AP CD2-associated protein -0.019992
ARF1 ADP-ribosylation factor 1 -0.0199847
SMC4 structural maintenance of chromosomes 4 -0.0199833
INTS6 integrator complex subunit 6 -0.0198578
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0198572
TUBB tubulin, beta class I -0.0198341
TCF12 transcription factor 12 -0.0198076
TRIM56 tripartite motif containing 56 -0.019721